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R

Raymond G. Sierra

SLAC National Accelerator Laboratory
H指数:45
被引数:1.1万

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Structural Mechanism of an Efficacy Photoswitch Targeting the β2-adrenergic Receptor

靶向β2-肾上腺素受体的效应光开关的结构机制

Angewandte Chemie International Edition
IF16.9
2026-03-180
OAAI
Robin Stipp; Quentin Bertrand; Matilde Trabuco; Anna Duran-Corbera; Maria Tindara Ignazzitto; Hannah Glover; Fabienne Stierli; Juanlo Catena; Melissa Carrillo; Sina Hartmann; Hans-Peter Seidel; Matthias Mulder; Thomas Mason; Yasushi Kondo; Maximillian Wranik; Martin Appleby; Christoph Sager; Raymond Sierra; Gregory Gate; Pamela Schleissner; Xinxin Cheng; Tobias Weinert; Robert Cheng; Sandra Mous; John H. Beale; Michal Kepa; Amadeu Llebaria; Michael Hennig; Xavier Rovira; Joerg Standfuss
Changes in an enzyme ensemble during catalysis observed by high-resolution XFEL crystallography
SCIENCE ADVANCES
IF12.5
2024-03-292
OAAI
Smith, Nathan; Dasgupta, Medhanjali; Wych, David C.; Dolamore, Cole; Sierra, Raymond G.; Lisova, Stella; Marchany-Rivera, Darya; Cohen, Aina E.; Boutet, Sebastien; Hunter, Mark S.; Kupitz, Christopher; Poitevin, Frederic; Moss III, Frank R.; Mittan-Moreau, David W.; Brewster, Aaron S.; Sauter, Nicholas K.; Young, Iris D.; Wolff, Alexander M.; Tiwari, Virendra K.; Kumar, Nivesh; Berkowitz, David B.; Hadt, Ryan G.; Thompson, Michael C.; Follmer, Alec H.; Wall, Michael E.; Wilson, Mark A.
Engineering Supramolecular Hybrid Architectures with Directional Organofluorine Bonds
SMALL SCIENCE
IF8.3
2023-12-134
OAAI
Kotei, Patience A.; Paley, Daniel W.; Oklejas, Vanessa; Mittan-Moreau, David W.; Schriber, Elyse A.; Aleksich, Mariya; Willson, Maggie C.; Inoue, Ichiro; Owada, Shigeki; Tono, Kensuke; Sugahara, Michihiro; Inaba-Inoue, Satomi; Aquila, Andrew; Poitevin, Frederic; Blaschke, Johannes P.; Lisova, Stella; Hunter, Mark S.; Sierra, Raymond G.; Gascon, Jose A.; Sauter, Nicholas K.; Brewster, Aaron S.; Hohman, James Nathan
Heterogeneity in M. tuberculosis β-lactamase inhibition by Sulbactam
NATURE COMMUNICATIONS
IF15.7
2023-09-0710
OAAI
Malla, Tek Narsingh; Zielinski, Kara; Aldama, Luis; Bajt, Sasa; Feliz, Denisse; Hayes, Brendon; Hunter, Mark; Kupitz, Christopher; Lisova, Stella; Knoska, Juraj; Martin-Garcia, Jose Manuel; Mariani, Valerio; Pandey, Suraj; Poudyal, Ishwor; Sierra, Raymond G.; Tolstikova, Alexandra; Yefanov, Oleksandr; Yoon, Chung Hong; Ourmazd, Abbas; Fromme, Petra; Schwander, Peter; Barty, Anton; Chapman, Henry N.; Stojkovic, Emina A.; Batyuk, Alexander; Boutet, Sebastien; Phillips, George N.; Pollack, Lois; Schmidt, Marius
XFEL Microcrystallography of Self-Assembling Silver n-Alkanethiolates
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
2023-07-3113
PRE
Aleksich, Mariya; Paley, Daniel W.; Schriber, Elyse A.; Linthicum, Will; Oklejas, Vanessa; Mittan-Moreau, David W.; Kelly, Ryan P.; Kotei, Patience A.; Ghodsi, Anita; Sierra, Raymond G.; Aquila, Andrew; Poitevin, Freïdeïric; Blaschke, Johannes P.; Vakili, Mohammad; Milne, Christopher J.; Dall'Antonia, Fabio; Khakhulin, Dmitry; Ardana-Lamas, Fernando; Lima, Frederico; Valerio, Joana; Han, Huijong; Gallo, Tamires; Yousef, Hazem; Turkot, Oleksii; Macias, Ivette J. Bermudez J.; Kluyver, Thomas; Schmidt, Philipp; Gelisio, Luca; Round, Adam R.; Jiang, Yifeng; Vinci, Doriana; Uemura, Yohei; Kloos, Marco; Hunter, Mark; Mancuso, Adrian P.; Huey, Bryan D.; Parent, Lucas R.; Sauter, Nicholas K.; Brewster, Aaron S.; Hohman, J. Nathan
Modular droplet injector for sample conservation providing new structural insight for the conformational heterogeneity in the disease-associated NQO1 enzyme
LAB ON A CHIP
IF5.4
2023-01-014
PRE
Doppler, Diandra; Sonker, Mukul; Egatz-Gomez, Ana; Grieco, Alice; Zaare, Sahba; Jernigan, Rebecca; Meza-Aguilar, Jose Domingo; Rabbani, Mohammad T. T.; Manna, Abhik; Alvarez, Roberto C. C.; Karpos, Konstantinos; Cruz Villarreal, Jorvani C.; Nelson, Garrett; Yang, Jay-How; Carrion, Jackson; Morin, Katherine; Ketawala, Gihan K. K.; Pey, Angel L. L.; Ruiz-Fresneda, Miguel Angel; Pacheco-Garcia, Juan Luis; Hermoso, Juan A. A.; Nazari, Reza; Sierra, Raymond; Hunter, Mark S. S.; Batyuk, Alexander; Kupitz, Christopher J. J.; Sublett, Robert E. E.; Lisova, Stella; Mariani, Valerio; Boutet, Sebastien; Fromme, Raimund; Grant, Thomas D. D.; Botha, Sabine; Fromme, Petra; Kirian, Richard A. A.; Martin-Garcia, Jose Manuel; Ros, Alexandra
Endogenous Retroviral Elements Generate Pathologic Neutrophils in Pulmonary Arterial Hypertension
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
IF19.4
2022-10-1517
OAAI
Taylor, Shalina; Isobe, Sarasa; Cao, Aiqin; Contrepois, Kevin; Benayoun, Berenice A.; Jiang, Lihua; Wang, Lingli; Melemenidis, Stavros; Ozen, Mehmet O.; Otsuki, Shoichiro; Shinohara, Tsutomu; Sweatt, Andrew J.; Kaplan, Jordan; Moonen, Jan-Renier; Marciano, David P.; Gu, Mingxia; Miyagawa, Kazuya; Hayes, Brandon; Sierra, Raymond G.; Kupitz, Christopher J.; Del Rosario, Patricia A.; Hsi, Andrew; Thompson, A. A. Roger; Ariza, Maria E.; Demirci, Utkan; Zamanian, Roham T.; Haddad, Francois; Nicolls, Mark R.; Snyder, Michael P.; Rabinovitch, Marlene
De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals
NATURE COMMUNICATIONS
IF15.7
2022-07-2816
OAAI
Tetreau, Guillaume; Sawaya, Michael R.; De Zitter, Elke; Andreeva, Elena A.; Banneville, Anne-Sophie; Schibrowsky, Natalie A.; Coquelle, Nicolas; Brewster, Aaron S.; Gruenbein, Marie Luise; Kovacs, Gabriela Nass; Hunter, Mark S.; Kloos, Marco; Sierra, Raymond G.; Schiro, Giorgio; Qiao, Pei; Stricker, Myriam; Bideshi, Dennis; Young, Iris D.; Zala, Ninon; Engilberge, Sylvain; Gorel, Alexander; Signor, Luca; Teulon, Jean-Marie; Hilpert, Mario; Foucar, Lutz; Bielecki, Johan; Bean, Richard; de Wijn, Raphael; Sato, Tokushi; Kirkwood, Henry; Letrun, Romain; Batyuk, Alexander; Snigireva, Irina; Fenel, Daphna; Schubert, Robin; Canfield, Ethan J.; Alba, Mario M.; Laporte, Frederic; Despres, Laurence; Bacia, Maria; Roux, Amandine; Chapelle, Christian; Riobe, Francois; Maury, Olivier; Ling, Wai Li; Boutet, Sebastien; Mancuso, Adrian; Gutsche, Irina; Girard, Eric; Barends, Thomas R. M.; Pellequer, Jean-Luc; Park, Hyun-Woo; Laganowsky, Arthur D.; Rodriguez, Jose; Burghammer, Manfred; Shoeman, Robert L.; Doak, R. Bruce; Weik, Martin; Sauter, Nicholas K.; Federici, Brian; Cascio, Duilio; Schlichting, Ilme; Colletier, Jacques-Philippe
Intersubunit Coupling Enables Fast CO2-Fixation by Reductive Carboxylases
ACS CENTRAL SCIENCE
IF10.4
2022-04-2510
OAAI
DeMirci, Hasan; Rao, Yashas; Stoffel, Gabriele M.; Vogeli, Bastian; Schell, Kristina; Gomez, Aharon; Batyuk, Alexander; Gati, Cornelius; Sierra, Raymond G.; Hunter, Mark S.; Dao, E. Han; Ciftci, Halil, I; Hayes, Brandon; Poitevin, Fredric; Li, Po-Nan; Kaur, Manat; Tono, Kensuke; Saez, David Adrian; Deutsch, Samuel; Yoshikuni, Yasuo; Grubmueller, Helmut; Erb, Tobias J.; Vohringer-Martinez, Esteban; Wakatsuki, Soichi
Cooperative allostery and structural dynamics of streptavidin at cryogenic- and ambient-temperature
COMMUNICATIONS BIOLOGY
IF5.1
2022-01-206
OAAI
Ayan, Esra; Yuksel, Busra; Destan, Ebru; Ertem, Fatma Betul; Yildirim, Gunseli; Eren, Meryem; Yefanov, Oleksandr M.; Barty, Anton; Tolstikova, Alexandra; Ketawala, Gihan K.; Botha, Sabine; Dao, E. Han; Hayes, Brandon; Liang, Mengning; Seaberg, Matthew H.; Hunter, Mark S.; Batyuk, Alexander; Mariani, Valerio; Su, Zhen; Poitevin, Frederic; Yoon, Chun Hong; Kupitz, Christopher; Cohen, Aina; Doukov, Tzanko; Sierra, Raymond G.; Dag, Cagdas; DeMirci, Hasan
Chemical crystallography by serial femtosecond X-ray diffraction
Nature
IF48.5
2022-01-190
OAAI
Elyse A. Schriber; Daniel W. Paley; Robert Bolotovsky; Daniel J. Rosenberg; Raymond G. Sierra; Andrew Aquila; Derek Mendez; Frédéric Poitevin; Johannes P. Blaschke; Asmit Bhowmick; Ryan P. Kelly; Mark Hunter; Brandon Hayes; Derek C. Popple; Matthew Yeung; Carina Pareja-Rivera; Stella Lisova; Kensuke Tono; Michihiro Sugahara; Shigeki Owada; Tevye Kuykendall; Kaiyuan Yao; P. James Schuck; Diego Solis-Ibarra; Nicholas K. Sauter; Aaron S. Brewster; J. Nathan Hohman
Structural insight into host plasma membrane association and assembly of HIV-1 matrix protein
SCIENTIFIC REPORTS
IF3.9
2021-08-049
OAAI
Ciftci, Halilibrahim; Tateishi, Hiroshi; Koiwai, Kotaro; Koga, Ryoko; Anraku, Kensaku; Monde, Kazuaki; Dag, Cagdas; Destan, Ebru; Yuksel, Busra; Ayan, Esra; Yildirim, Gunseli; Yigin, Merve; Ertem, F. Betul; Shafiei, Alaleh; Guven, Omur; Besler, Sabri O.; Sierra, Raymond G.; Yoon, Chun Hong; Su, Zhen; Liang, Mengling; Acar, Burcin; Haliloglu, Turkan; Otsuka, Masami; Yumoto, Fumiaki; Fujita, Mikako; Senda, Toshiya; DeMirci, Hasan
Early-stage dynamics of chloride ion-pumping rhodopsin revealed by a femtosecond X-ray laser
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2021-03-2247
OAAI
Yun, Ji-Hye; Li, Xuanxuan; Yue, Jianing; Park, Jae-Hyun; Jin, Zeyu; Li, Chufeng; Hu, Hao; Shi, Yingchen; Pandey, Suraj; Carbajo, Sergio; Boutet, Sebastien; Hunter, Mark S.; Liang, Mengning; Sierra, Raymond G.; Lane, Thomas J.; Zhou, Liang; Weierstall, Uwe; Zatsepin, Nadia A.; Ohki, Mio; Tame, Jeremy R. H.; Park, Sam-Yong; Spence, John C. H.; Zhang, Wenkai; Schmidt, Marius; Lee, Weontae; Liu, Haiguang
Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade
NATURE COMMUNICATIONS
IF15.7
2020-03-0227
OAAI
Tetreau, Guillaume; Banneville, Anne-Sophie; Andreeva, Elena A.; Brewster, Aaron S.; Hunter, Mark S.; Sierra, Raymond G.; Teulon, Jean-Marie; Young, Iris D.; Burke, Niamh; Grunewald, Tilman A.; Beaudouin, Joel; Snigireva, Irina; Fernandez-Luna, Maria Teresa; Burt, Alister; Park, Hyun-Woo; Signor, Luca; Bafna, Jayesh A.; Sadir, Rabia; Fenel, Daphna; Boeri-Erba, Elisabetta; Bacia, Maria; Zala, Ninon; Laporte, Frederic; Despres, Laurence; Weik, Martin; Boutet, Sebastien; Rosenthal, Martin; Coquelle, Nicolas; Burghammer, Manfred; Cascio, Duilio; Sawaya, Michael R.; Winterhalter, Mathias; Gratton, Enrico; Gutsche, Irina; Federici, Brian; Pellequer, Jean-Luc; Sauter, Nicholas K.; Colletier, Jacques-Philippe
Mix-and-inject XFEL crystallography reveals gated conformational dynamics during enzyme catalysis
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2019-12-0457
OAAI
Dasgupta, Medhanjali; Budday, Dominik; de Oliveira, Saulo H. P.; Madzelan, Peter; Marchany-Rivera, Darya; Seravalli, Javier; Hayes, Brandon; Sierra, Raymond G.; Boutet, Sebastien; Hunter, Mark S.; Alonso-Mori, Roberto; Batyuk, Alexander; Wierman, Jennifer; Lyubimov, Artem; Brewster, Aaron S.; Sauter, Nicholas K.; Applegate, Gregory A.; Tiwari, Virendra K.; Berkowitz, David B.; Thompson, Michael C.; Cohen, Aina E.; Fraser, James S.; Wall, Michael E.; van den Bedem, Henry; Wilson, Mark A.

研究方向

暂未获取到该数据
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H 指数:56论文数:247被引数:1.4万
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H 指数:74论文数:334被引数:2.3万
M
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H 指数:48论文数:151被引数:1.3万
N
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H 指数:54论文数:266被引数:1.7万
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H 指数:57论文数:234被引数:1.5万
A
Anton Barty
H 指数:78论文数:396被引数:2.4万
S
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H 指数:61论文数:505被引数:1.7万
K
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H 指数:39论文数:143被引数:1.0万