Youngchang Kim - Publications, H-index & Citations

Youngchang Kim

structural biology center

53H指数

334论文数

1.1W被引数

收录论文 76

发表时间

Structural basis for substrate-assisted catalysis and small-molecule inhibition of alphavirus macrodomains α病毒巨结构域的底物辅助催化和小分子抑制的结构基础

Communications Chemistry

IF6.2

2026-09-17

OAAI

Youngchang Kim; Nazar Gora; Changsoo Chang; Lucy Stols; Michael Endres; Zamal Ahmed; Darin E. Jones; Todd M. Link; Cody J. Cris; Subhash C. Verma; Gyorgy Babnigg; Karolina Michalska; John A. Tainer; Greg L. Hura; Andrzej Joachimiak

Targeted Discovery of β-Branched Conjugated Polyketides from Bacteria Based on Genomic and Metabolomic Hallmarks 基于基因组学和代谢组学特征，靶向发现细菌来源的β-支链共轭聚酮类化合物。

JACS Au

IF8.7

2026-03-03

OAAI

Jinsheng Cui; Ilnam Kang; Haewon Lee; Bo Eun Heo; Suhyun Ye; Jayho Lee; Dong Hyun Moon; Eun Seo Bae; Chae Won Ock; Daniel Shin; Joon Soo An; Hahk-Soo Kang; Sang Kook Lee; Ki-Bong Oh; Illhwan Cho; Hye Yun Kim; YoungSoo Kim; Jichan Jang; Jang-Cheon Cho; Dong-Chan Oh

Bacteria export alarmone synthetases that produce (p)ppApp and (p)ppGpp 细菌分泌产生(p)ppApp和(p)ppGpp的警报素合成酶。

MBIO

IF4.7

2025-11-01

PREAI

Ahmad, Shehryar; Guedez, Andrea G.; Manisa, Berti; Adewale, Abdulmalik; Tsang, Kara K.; Schiefer, Vanessa; Bullen, Nathan P.; Thakar, Harmy; Kim, Youngchang; Wang, Boyuan; Whitney, John C.

Antibacterial ADP-ribosyl cyclase toxins inhibit bacterial growth by rapidly depleting NAD(P)+抗菌ADP核糖基环化酶毒素通过快速耗尽NAD(P)+来抑制细菌生长

Journal of Biological Chemistry

IF3.9

2025-07-16

OAAI

Jake Colautti; Youngchang Kim; John C. Whitney

A conserved chaperone protein is required for the formation of a noncanonical type VI secretion system spike tip complex

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2025-03-01

OAAI

Sachar, Kartik; Kanarek, Katarzyna; Colautti, Jake; Kim, Youngchang; Bosis, Eran; Prehna, Gerd; Salomon, Dor; Whitney, John C.

Role of the Mobile Active Site Flap in IMP Dehydrogenase Inhibitor Binding

ACS INFECTIOUS DISEASES

IF3.8

2025-01-29

PREAI

Wang, Xingyou; Rosenberg, Masha M.; Kim, Youngchang; Maltseva, Natalia; Cuny, Gregory D.; Joachimiak, Andrzej; Kuzmic, Petr; Hedstrom, Lizbeth

Revealing reaction intermediates in one-carbon elongation by thiamine diphosphate/CoA-dependent enzyme family

COMMUNICATIONS CHEMISTRY

IF6.2

2024-07-21

OAAI

Kim, Youngchang; Lee, Seung Hwan; Gade, Priyanka; Nattermann, Maren; Maltseva, Natalia; Endres, Michael; Chen, Jing; Wichmann, Philipp; Hu, Yang; Marchal, Daniel G.; Yoshikuni, Yasuo; Erb, Tobias J.; Gonzalez, Ramon; Michalska, Karolina; Joachimiak, Andrzej

Structure of a tripartite protein complex that targets toxins to the type VII secretion system 将毒素靶向VII型分泌系统的三部分蛋白质复合物的结构

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-01-09

OAAI

Klein, Timothy A.; Shah, Prakhar Y.; Gkragkopoulou, Polyniki; Grebenc, Dirk W.; Kim, Youngchang; Whitney, John C.

Structure and enzymatic characterization of CelD endoglucanase from the anaerobic fungus Piromyces finnis

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

IF4.3

2023-08-07

OAAI

Dementiev, Alexey; Lillington, Stephen P.; Jin, Shiyan; Kim, Youngchang; Jedrzejczak, Robert; Michalska, Karolina; Joachimiak, Andrzej; O'Malley, Michelle A.

Identification of a broadly conserved family of enzymes that hydrolyze (p)ppApp

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-03-29

OAAI

Ahmad, Shehryar; Gordon, Isis J.; Tsang, Kara K.; Alexei, Andrea G.; Sychantha, David; Colautti, Jake; Trilesky, Sarah L.; Kim, Youngchang; Wang, Boyuan; Whitney, John C.

Raf Kinase Inhibitory Protein Function Is Regulated via a Flexible Pocket and Novel Phosphorylation-Dependent Mechanism

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-21

OAAI

Granovsky, Alexey E.; Clark, Matthew C.; McElheny, Dan; Heil, Gary; Hong, Jia; Liu, Xuedong; Kim, Youngchang; Joachimiak, Grazyna; Joachimiak, Andrzej; Koide, Shohei; Rosner, Marsha Rich

Structure and Dimerization Properties of the Aryl Hydrocarbon Receptor PAS-A Domain

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

OAAI

Wu, Dalei; Potluri, Nalini; Kim, Youngchang; Rastinejad, Fraydoon

Time-resolved β-lactam cleavage by L1 metallo-β-lactamase

NATURE COMMUNICATIONS

IF15.7

2022-11-30

OAAI

Wilamowski, M.; Sherrell, D. A.; Kim, Y.; Lavens, A.; Henning, R. W.; Lazarski, K.; Shigemoto, A.; Endres, M.; Maltseva, N.; Babnigg, G.; Burdette, S. C.; Srajer, V.; Joachimiak, A.

Dual Targeting Factors Are Required for LXG Toxin Export by the Bacterial Type VIIb Secretion System

MBIO

IF4.7

2022-10-26

OAAI

Klein, Timothy A.; Grebenc, Dirk W.; Shah, Prakhar Y.; McArthur, Owen D.; Dickson, Brandon H.; Surette, Michael G.; Kim, Youngchang; Whitney, John C.

Crystal structure of Campylobacter jejuni lipoprotein Cj1090c

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2022-10-17

OAAI

Paek, Seonghee; Kawai, Fumihiro; Venisetty, Nilamani; Kim, Youngchang; Yeo, Hye-Jeong

The first crystal structure of a xylobiose-bound xylobiohydrolase with high functional specificity from the bacterial glycoside hydrolase family 30, subfamily 10

FEBS LETTERS

IF3

2022-08-04

OAAI

St John, Franz J.; Crooks, Casey; Kim, Youngchang; Tan, Kemin; Joachimiak, Andrzej

Functional and Structural Characterization of Diverse NfsB Chloramphenicol Reductase Enzymes from Human Pathogens

MICROBIOLOGY SPECTRUM

IF3.8

2022-04-27

OAAI

Mullowney, Michael W.; Maltseva, Natalia, I; Endres, Michael; Kim, Youngchang; Joachimiak, Andrzej; Crofts, Terence S.

Target highlights in CASP14: Analysis of models by structure providers CASP14中的目标亮点: 结构提供者对模型的分析

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2021-10-10

OAAI

Alexander, Leila T.; Lepore, Rosalba; Kryshtafovych, Andriy; Adamopoulos, Athanassios; Alahuhta, Markus; Arvin, Ann M.; Bomble, Yannick J.; Bottcher, Bettina; Breyton, Cecile; Chiarini, Valerio; Chinnam, Naga Babu; Chiu, Wah; Fidelis, Krzysztof; Grinter, Rhys; Gupta, Gagan D.; Hartmann, Marcus D.; Hayes, Christopher S.; Heidebrecht, Tatjana; Ilari, Andrea; Joachimiak, Andrzej; Kim, Youngchang; Linares, Romain; Lovering, Andrew L.; Lunin, Vladimir V.; Lupas, Andrei N.; Makbul, Cihan; Michalska, Karolina; Moult, John; Mukherjee, Prasun K.; Nutt, William Sam; Oliver, Stefan L.; Perrakis, Anastassis; Stols, Lucy; Tainer, John A.; Topf, Maya; Tsutakawa, Susan E.; Valdivia-Delgado, Mauricio; Schwede, Torsten

The Enzymatic Activity of Inosine 5′-Monophosphate Dehydrogenase May Not Be a Vulnerable Target for Staphylococcus aureus Infections

ACS INFECTIOUS DISEASES

IF3.8

2021-09-30

OAAI

Modi, Gyan; Marqus, Gary M.; Vippila, Mohana Rao; Gollapalli, Deviprasad R.; Kim, Youngchang; Manna, Adhar C.; Chacko, Shibin; Maltseva, Natalia; Wang, Xingyou; Cullinane, Ryan T.; Zhang, Yubo; Kotler, Judy L. M.; Kuzmic, Petr; Zhang, Minjia; Lawson, Ann P.; Joachimiak, Andrzej; Cheung, Ambrose; Snider, Barry B.; Rothstein, David M.; Cuny, Gregory D.; Hedstrom, Lizbeth

Transient and stabilized complexes of Nsp7, Nsp8, and Nsp12 in SARS-CoV-2 replication

BIOPHYSICAL JOURNAL

IF3.1

2021-08-01

OAAI

Wilamowski, Mateusz; Hammel, Michal; Leite, Wellington; Zhang, Qiu; Kim, Youngchang; Weiss, Kevin L.; Jedrzejczak, Robert; Rosenberg, Daniel J.; Fan, Yichong; Wower, Jacek; Bierma, Jan C.; Sarker, Altaf H.; Tsutakawa, Susan E.; Pingali, Sai Venkatesh; O'Neill, Hugh M.; Joachimiak, Andrzej; Hura, Greg L.

研究方向