Paul J. Tesar - Publications, H-index & Citations

Paul J. Tesar

case western reserve university school of medicine

41H指数

119论文数

9.7K被引数

收录论文 54

发表时间

Transient gene melting governs the timing of oligodendrocyte maturation 瞬时基因融解调控少突胶质细胞成熟的时机

Cell

IF42.5

2025-08-25

PREAI

Kevin C. Allan; Jesse J. Zhan; Andrew R. Morton; Erin F. Cohn; Marissa A. Scavuzzo; Anushka Nikhil; Matthew S. Elitt; Benjamin L.L. Clayton; Lucille R. Hu; H. Elizabeth Shick; Jost K. Vrabic; Hannah E. Olsen; Daniel C. Factor; Jonathan E. Henninger; Gemma Bachmann; Berit E. Powers; Richard A. Young; Charles Y. Lin; Peter C. Scacheri; Tyler E. Miller; Paul J. Tesar

Plasticity of the mammalian integrated stress response 哺乳动物整合应激反应的塑性

NATURE

IF48.5

2025-03-26

OAAI

Chen, Chien-Wen; Papadopoli, David; Szkop, Krzysztof J.; Guan, Bo-Jhih; Alzahrani, Mohammed; Wu, Jing; Jobava, Raul; Asraf, Mais M.; Krokowski, Dawid; Vourekas, Anastasios; Merrick, William C.; Komar, Anton A.; Koromilas, Antonis E.; Gorospe, Myriam; Payea, Matthew J.; Wang, Fangfang; Clayton, Benjamin L. L.; Tesar, Paul J.; Schaffer, Ashleigh; Miron, Alexander; Bederman, Ilya; Jankowsky, Eckhard; Vogel, Christine; Valasek, Leos Shivaya; Dinman, Jonathan D.; Zhang, Youwei; Tirosh, Boaz; Larsson, Ola; Topisirovic, Ivan; Hatzoglou, Maria

Astrocyte and oligodendrocyte pathology in Alzheimer's disease 星形胶质细胞和少突胶质细胞在阿尔茨海默病中的病理变化

NEUROTHERAPEUTICS

IF6.9

2025-02-01

OAAI

Ziar, Rania; Tesar, Paul J.; Clayton, Benjamin L. L.

Patient iPSC models reveal glia-intrinsic phenotypes in multiple sclerosis 患者iPSC模型揭示多发性硬化症中的神经胶质固有表型

CELL STEM CELL

IF20.4

2024-11-01

OAAI

Clayton, Benjamin L. L.; Barbar, Lilianne; Sapar, Maria; Kalpana, Kriti; Rao, Chandrika; Migliori, Bianca; Rusielewicz, Tomasz; Paull, Daniel; Brenner, Katie; Moroziewicz, Dorota; Sand, Ilana Katz; Casaccia, Patrizia; Tesar, Paul J.; Fossati, Valentina

Pelizaeus-Merzbacher disease: on the cusp of myelin medicine

Trends in Molecular Medicine

IF13.8

2024-05-01

PREAI

Elitt, Matthew S.; Tesar, Paul J.

Discovery and Optimization of Selective Brain-Penetrant EBP Inhibitors that Enhance Oligodendrocyte Formation

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-03-12

PREAI

Dorel, Ruth; Sun, Dawei; Carruthers, Nicholas; Castanedo, Georgette M.; Ung, Peter M. U.; Factor, Daniel C.; Li, Tianbo; Baumann, Hannah; Janota, Danielle; Pang, Jodie; Salphati, Laurent; Meklemburg, Robert; Korman, Allison J.; Harper, Halie E.; Stubblefield, Samantha; Payandeh, Jian; Mchugh, Daniel; Lang, Bradley T.; Tesar, Paul J.; Dere, Edward; Masureel, Matthieu; Adams, Drew J.; Volgraf, Matthew; Braun, Marie-Gabrielle

RETRACTION: NPTX1 Regulates Neural Lineage Specification from Human Pluripotent Stem Cells (Retraction of Vol 6, Pg 724, 2014)

CELL REPORTS

IF6.9

2024-01-01

OAAI

Boles, Nathan C.; Hirsch, Sarah E.; Le, Sheila; Corneo, Barbara; Najm, Fadi; Minotti, Andrew P.; Wang, Qingjie; Lotz, Steven; Tesar, Paul J.; Fasano, Christopher A.

Oligodendrocyte differentiation alters tRNA modifications and codon optimality-mediated mRNA decay

NATURE COMMUNICATIONS

IF15.7

2022-08-25

OAAI

Martin, Sophie; Allan, Kevin C.; Pinkard, Otis; Sweet, Thomas; Tesar, Paul J.; Coller, Jeff

Inhibition of SC4MOL and HSD17B7 shifts cellular sterol composition and promotes oligodendrocyte formation

RSC CHEMICAL BIOLOGY

IF3.1

2022-01-01

OAAI

Pleshinger, Matthew J.; Friedrich, Ryan M.; Hubler, Zita; Rivera-Leon, Adrianna M.; Gao, Farrah; Yan, David; Sax, Joel L.; Srinivasan, Ramya; Bederman, Ilya; Shick, H. Elizabeth; Tesar, Paul J.; Adams, Drew J.

Oligodendrocyte progenitor cell fate and function in development and disease

CURRENT OPINION IN CELL BIOLOGY

IF4.3

2021-12-01

OAAI

Clayton, Benjamin L. L.; Tesar, Paul J.

Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function

CELL STEM CELL

IF20.4

2021-02-01

OAAI

Allan, Kevin C.; Hu, Lucille R.; Scavuzzo, Marissa A.; Morton, Andrew R.; Gevorgyan, Artur S.; Cohn, Erin F.; Clayton, Benjamin L. L.; Bederman, Ilya R.; Hung, Stevephen; Bartels, Cynthia F.; Madhavan, Mayur; Tesar, Paul J.

Pathogenic Prion Protein Isoforms Are Not Present in Cerebral Organoids Generated from Asymptomatic Donors Carrying the E200K Mutation Associated with Familial Prion Disease

PATHOGENS

IF3.3

2020-06-18

OAAI

Foliaki, Simote T.; Groveman, Bradley R.; Yuan, Jue; Walters, Ryan; Zhang, Shulin; Tesar, Paul; Zou, Wenquan; Haigh, Cathryn L.

Oligodendrocyte Intrinsic miR-27a Controls Myelination and Remyelination

CELL REPORTS

IF6.9

2019-10-01

OAAI

Tripathi, Ajai; Volsko, Christina; Garcia, Jessie P.; Agirre, Eneritz; Allan, Kevin C.; Tesar, Paul J.; Trapp, Bruce D.; Castelo-Branco, Goncalo; Sim, Fraser J.; Dutta, Ranjan

The Chromatin Environment Around Interneuron Genes in Oligodendrocyte Precursor Cells and Their Potential for Interneuron Reprograming

FRONTIERS IN NEUROSCIENCE

IF3.2

2019-08-08

OAAI

Boshans, Linda L.; Factor, Daniel C.; Singh, Vijender; Liu, Jia; Zhao, Chuntao; Mandoiu, Ion; Lu, Q. Richard; Casaccia, Patrizia; Tesar, Paul J.; Nishiyama, Akiko

Developing therapeutic strategies to promote myelin repair in multiple sclerosis

EXPERT REVIEW OF NEUROTHERAPEUTICS

IF3.4

2019-06-20

PREAI

Baldassari, Laura E.; Feng, Jenny; Clayton, Benjamin L. L.; Oh, Se-Hong; Sakaie, Ken; Tesar, Paul J.; Wang, Yanming; Cohen, Jeffrey A.

Dysregulated Glial Differentiation in Schizophrenia May Be Relieved by Suppression of SMAD4-and REST-Dependent Signaling 精神分裂症的神经胶质细胞分化失调可能通过抑制SMAD4-and的休息依赖性信号来缓解

CELL REPORTS

IF6.9

2019-06-01

OAAI

Liu, Zhengshan; Osipovitch, Mikhail; Benraiss, Abdellatif; Huynh, Nguyen P. T.; Foti, Rossana; Bates, Janna; Chandler-Militello, Devin; Findling, Robert L.; Tesar, Paul J.; Nedergaard, Maiken; Windrem, Martha S.; Goldman, Steven A.

Diverse Chemical Scaffolds Enhance Oligodendrocyte Formation by Inhibiting CYP51, TM7SF2, or EBP

CELL CHEMICAL BIOLOGY

IF7.2

2019-04-01

OAAI

Allimuthu, Dharmaraja; Hubler, Zita; Najm, Fadi J.; Tang, Hong; Bederman, Ilya; Seibel, William; Tesar, Paul J.; Adams, Drew J.

NG2 expression in NG2 glia is regulated by binding of SoxE and bHLH transcription factors to a Cspg4 intronic enhancer

GLIA

IF5.1

2018-10-10

OAAI

Gotoh, Hitoshi; Wood, William M.; Patel, Kiran D.; Factor, Daniel C.; Boshans, Linda L.; Nomura, Tadashi; Tesar, Paul J.; Ono, Katsuhiko; Nishiyama, Akiko

Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells

NATURE COMMUNICATIONS

IF15.7

2018-09-13

OAAI

Lager, Angela M.; Corradin, Olivia G.; Cregg, Jared M.; Elitt, Matthew S.; Shick, H. Elizabeth; Clayton, Benjamin L. L.; Allan, Kevin C.; Olsen, Hannah E.; Madhavan, Mayur; Tesar, Paul J.

Chemical Screening Identifies Enhancers of Mutant Oligodendrocyte Survival and Unmasks a Distinct Pathological Phase in Pelizaeus-Merzbacher Disease

STEM CELL REPORTS

IF5.1

2018-09-01

OAAI

Elitt, Matthew S.; Shick, H. Elizabeth; Madhavan, Mayur; Allan, Kevin C.; Clayton, Benjamin L. L.; Weng, Chen; Miller, Tyler E.; Factor, Daniel C.; Barbar, Lilianne; Nawash, Baraa S.; Nevin, Zachary S.; Lager, Angela M.; Li, Yan; Jin, Fulai; Adams, Drew J.; Tesar, Paul J.

研究方向