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J

Johannes V. Swinnen

KU Leuven
H指数:76
被引数:2.1万

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Surface Plasmon Resonance as a Potential Diagnostic Tool for the Detection of CXC Chemokine Receptor 4 (CXCR4) on Extracellular Vesicles

表面等离激元共振作为检测细胞外囊泡上CXC趋化因子受体4（CXCR4）的潜在诊断工具

Biosensors
IF5.6
2026-03-280
OAAI
Kaat Verleye; Sam Noppen; Arnaud Boonen; Yagmur Yildizhan; Tom Van Loy; Cindy Heens; Frank Vanderhoydonc; Cláudio Pinheiro; Paula M. Pincela Lins; Annelies Bronckaers; An Hendrix; Johannes V. Swinnen; Dragana Spasic; Jeroen Lammertyn; Christophe Pannecouque; Dominique Schols
AMP-activated protein kinase-driven lipid droplet dynamics govern melanoma sensitivity to polyunsaturated fatty acid and iron-induced ferroptosis

AMP激活蛋白激酶驱动的脂滴动力学调控黑素瘤对多不饱和脂肪酸和铁诱导的铁死亡敏感性

Nature Communications
IF15.7
2025-12-170
OAAI
Sahar Motamedi; Nina Ravoet; Jonas Dehairs; Frank Vanderhoydonc; Abril Escamilla-Ayala; Malgorzata A. Sliwinska; Shuncong Wang; Jakub Idkowiak; Stefaan Soenen; Patrizia Agostinis; Jean-Christophe Marine; Johannes V. Swinnen
Dual lipid modulation overcomes ferroptosis resistance in high-risk neuroblastoma

双重脂质调控克服高危神经母细胞瘤的铁死亡抵抗

Cell Death & Differentiation
IF0
2025-11-260
OAAI
Ine Koeken; Magali Walravens; Roberto Fernández-Acosta; Ruben Van Hoyweghen; Iuliana Vintea; Yingyi Kong; Bianka Golba; Jonas Dehairs; Ali Talebi; Johannes V. Swinnen; Kaat Durinck; Adriana Mañas; Shinya Toyokuni; Gerben Menschaert; Maria Fedorova; Bruno G. De Geest; Behrouz Hassannia; Tom Vanden Berghe
Best practices and tools in R and Python for statistical processing and visualization of lipidomics and metabolomics data

脂组学和代谢组学数据统计分析与可视化的R和Python最佳实践及工具

Nature Communications
IF15.7
2025-09-300
OAAI
Jakub Idkowiak; Jonas Dehairs; Jana Schwarzerová; Dominika Olešová; Jacob X. M. Truong; Aleš Kvasnička; Marios Eftychiou; Ruben Cools; Xander Spotbeen; Robert Jirásko; Vullnet Veseli; Marco Giampà; Vincent de Laat; Lisa M. Butler; Wolfram Weckwerth; David Friedecký; Jonas Demeulemeester; Karel Hron; Johannes V. Swinnen; Michal Holčapek
Author Correction: Endoplasmic reticulum–mitochondria contacts are prime hotspots of phospholipid peroxidation driving ferroptosis

作者更正: 内质网-线粒体接触是磷脂过氧化驱动铁死亡的主要热点

Nature Cell Biology
IF19.1
2025-08-040
OAAI
Maria Livia Sassano; Yulia Y. Tyurina; Antigoni Diokmetzidou; Ellen Vervoort; Vladimir A. Tyurin; Sanket More; Rita La Rovere; Francesca Giordano; Geert Bultynck; Benjamin Pavie; Johan V. Swinnen; Hülya Bayir; Valerian E. Kagan; Luca Scorrano; Patrizia Agostinis
Glycosphingolipid synthesis is impaired in SLC35A2-CDG and improves with galactose supplementation

SLC35A2-CDG中糖鞘脂合成受损，且可通过添加半乳糖得到改善。

Cellular and Molecular Life Sciences
IF6.2
2025-06-270
OAAI
Andrea Jáñez Pedrayes; Sam De Craemer; Jakub Idkowiak; Dries Verdegem; Christian Thiel; Rita Barone; Mercedes Serrano; Tomáš Honzík; Eva Morava; Pieter Vermeersch; François Foulquier; Willy Morelle; Johannes V. Swinnen; Daisy Rymen; David Cassiman; Bart Ghesquière; Peter Witters
Early plasma ceramide and sphingomyelin levels reflect APOE genotype but not familial Alzheimer's disease gene mutations in female 5xFAD mice , with brain-region specific sphingolipid alterations

早期血浆鞘氨醇和神经鞘磷脂水平反映APOE基因型，而非家族性阿尔茨海默病基因突变，在雌性5xFAD小鼠中，伴有脑区特异性的鞘脂改变。

NEUROBIOLOGY OF DISEASE
IF5.6
2025-06-010
OAAI
van Kruining, Daan; Losen, Mario; Dehairs, Jonas; Swinnen, Johannes, V; Waelkens, Etienne; Honing, Maarten; Martinez-Martinez, Pilar
Targeting ELOVL6 to disrupt c-MYC driven lipid metabolism in pancreatic cancer enhances chemosensitivity

靶向ELOVL6以破坏胰腺癌中c-MYC驱动的脂质代谢，可增强化疗敏感性

NATURE COMMUNICATIONS
IF15.7
2025-02-160
OA
Garcia, Ana Garcia; Aporta, Maria Ferrer; Palma, German Vallejo; Trujillo, Antonio Giraldez; Castillo-Gonzalez, Raquel; Lozano, David Calzon; Perdiguero, Alberto; Munoz Velasco, Raul; Colina Castro, Miguel; de Simone Benito, Elena; Torres-Ruiz, Raul; Rodriguez-Perales, Sandra; Dehairs, Jonas; Swinnen, Johannes V.; Garcia-Canaveras, Juan Carlos; Lahoz, Agustin; Quiros, Sandra Montalvo; del Pozo-Rojas, Carlos; Luque Rioja, Clara; Monroy, Francisco; Herraez-Aguilar, Diego; Riano, Marina Alonso; Rodriguez Peralto, Jose Luis
Single cell and spatial transcriptomics highlight the interaction of club-like cells with immunosuppressive myeloid cells in prostate cancer
NATURE COMMUNICATIONS
IF15.7
2024-11-160
OAAI
Kiviaho, Antti; Eerola, Sini K.; Kallio, Heini M. L.; Andersen, Maria K.; Hoikka, Miina; Tiihonen, Aliisa M.; Salonen, Iida; Spotbeen, Xander; Giesen, Alexander; Parker, Charles T. A.; Taavitsainen, Sinja; Hantula, Olli; Marttinen, Mikael; Hermelo, Ismail; Ismail, Mazlina; Midtbust, Elise; Wess, Maximilian; Devlies, Wout; Sharma, Abhibhav; Krossa, Sebastian; Hakkinen, Tomi; Afyounian, Ebrahim; Vandereyken, Katy; Kint, Sam; Kesseli, Juha; Tolonen, Teemu; Tammela, Teuvo L. J.; Viset, Trond; Storkersen, Oystein; Giskeodegard, Guro F.; Rye, Morten B.; Murtola, Teemu; Erickson, Andrew; Latonen, Leena; Bova, G. Steven; Mills, Ian G.; Joniau, Steven; Swinnen, Johannes V.; Voet, Thierry; Mirtti, Tuomas; Attard, Gerhardt; Claessens, Frank; Visakorpi, Tapio; Rautajoki, Kirsi J.; Tessem, May-Britt; Urbanucci, Alfonso; Nykter, Matti
Secreted Apoe rewires melanoma cell state vulnerability to ferroptosis

分泌的Apoe重新连接黑色素瘤细胞状态对铁死亡的脆弱性

SCIENCE ADVANCES
IF12.5
2024-10-181
OAAI
More, Sanket; Bonnereau, Julie; Wouters, David; Spotbeen, Xander; Karras, Panagiotis; Rizzollo, Francesca; Killian, Theo; Venken, Tom; Naulaerts, Stefan; Vervoort, Ellen; Ganne, Maarten; Nittner, David; Verhoeven, Jelle; Bechter, Oliver; Bosisio, Francesca; Lambrechts, Diether; Sifrim, Alejandro; Stockwell, Brent R.; Swinnen, Johannes V.; Marine, Jean Christophe; Agostinis, Patrizia
Intrinsic temperature increase drives lipid metabolism towards ferroptosis evasion and chemotherapy resistance in pancreatic cancer

内在性温度升高促使脂质代谢向铁死亡逃逸和胰腺癌化疗耐药方向发展

NATURE COMMUNICATIONS
IF15.7
2024-10-020
OAAI
de Laat, Vincent; Topal, Halit; Spotbeen, Xander; Talebi, Ali; Dehairs, Jonas; Idkowiak, Jakub; Vanderhoydonc, Frank; Ostyn, Tessa; Zhao, Peihua; Jacquemyn, Maarten; Woelk, Michele; Sablina, Anna; Augustyns, Koen; Vanden Berghe, Tom; Roskams, Tania; Daelemans, Dirk; Fedorova, Maria; Topal, Baki; Swinnen, Johannes V.
A deep phenotyping study in mouse and iPSC models to understand the role of oligodendroglia in optic neuropathy in Wolfram syndrome
ACTA NEUROPATHOLOGICA COMMUNICATIONS
IF5.7
2024-08-280
OAAI
Ahuja, K.; Vandenabeele, M.; Nami, F.; Lefevere, E.; Van Hoecke, J.; Bergmans, S.; Claes, M.; Vervliet, T.; Neyrinck, K.; Burg, T.; De Herdt, D.; Bhaskar, P.; Zhu, Y.; Looser, Z. J.; Loncke, J.; Gsell, W.; Plaas, M.; Agostinis, P.; Swinnen, J. V.; van den Bosch, L.; Bultynck, G.; Saab, A. S.; Wolfs, E.; Chai, Y. C.; Himmelreich, U.; Verfaillie, C.; Moons, L.; De Groef, L.
Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs (vol 147, 6, 2024)

来自hipsc的突变FUS少突胶质祖细胞中MAM完整性的破坏 (147卷，6，2024)

ACTA NEUROPATHOLOGICA
IF9.3
2024-06-130
OAAI
Zhu, Yingli; Burg, Thibaut; Neyrinck, Katrien; Vervliet, Tim; Nami, Fatemeharefeh; Vervoort, Ellen; Ahuja, Karan; Sassano, Maria Livia; Chai, Yoke Chin; Tharkeshwar, Arun Kumar; De Smedt, Jonathan; Hu, Haibo; Bultynck, Geert; Agostinis, Patrizia; Swinnen, Johannes V.; van den Bosch, Ludo; da Costa, Rodrigo Furtado Madeiro; Verfaillie, Catherine
PMP22 duplication dysregulates lipid homeostasis and plasma membrane organization in developing human Schwann cells

PMP22复制在发育中的人类雪旺氏细胞中异常调节脂质稳态和质膜组织

BRAIN
IF11.7
2024-05-143
OAAI
Prior, Robert; Silva, Alessio; Vangansewinkel, Tim; Idkowiak, Jakub; Tharkeshwar, Arun Kumar; Hellings, Tom P.; Michailidou, Iliana; Vreijling, Jeroen; Loos, Maarten; Koopmans, Bastijn; Vlek, Nina; Agaser, Cedrick; Kuipers, Thomas B.; Michiels, Christine; Rossaert, Elisabeth; Verschoren, Stijn; Vermeire, Wendy; de Laat, Vincent; Dehairs, Jonas; Eggermont, Kristel; van den Biggelaar, Diede; Bademosi, Adekunle T.; Meunier, Frederic A.; Vandeven, Martin; Van Damme, Philip; Mei, Hailiang; Swinnen, Johannes, V; Lambrichts, Ivo; Baas, Frank; Fluiter, Kees; Wolfs, Esther; van den Bosch, Ludo
ACSM1 and ACSM3 Regulate Fatty Acid Metabolism to Support Prostate Cancer Growth and Constrain Ferroptosis

ACSM1和ACSM3调节脂肪酸代谢以支持前列腺癌生长并抑制铁死亡

CANCER RESEARCH
IF16.6
2024-04-242
PRE
Shrestha, Raj K.; Nassar, Zeyad D.; Hanson, Adrienne R.; Iggo, Richard; Townley, Scott L.; Dehairs, Jonas; Mah, Chui Y.; Helm, Madison; Alizadeh-Ghodsi, Mohammadreza; Pickering, Marie; Ghesquiere, Bart; Watt, Matthew J.; Quek, Lake-Ee; Hoy, Andrew J.; Tilley, Wayne D.; Swinnen, Johannes V.; Butler, Lisa M.; Selth, Luke A.

研究方向

暂未获取到该数据
J
Jonas Dehairs
H 指数:30论文数:373被引数:4,249
G
Guido Verhoeven
H 指数:70论文数:413被引数:1.5万
P
Patrizia Agostinis
H 指数:99论文数:472被引数:6.2万
L
Lisa M. Butler
H 指数:56论文数:535被引数:1.1万
F
Frank Vanderhoydonc
H 指数:21论文数:95被引数:2,661
W
Walter Heyns
H 指数:43论文数:243被引数:7,944
R
Rita Derua
H 指数:45论文数:232被引数:6,788
Z
Zeyad D. Nassar
H 指数:29论文数:186被引数:1,889
E
Etienne Waelkens
H 指数:58论文数:428被引数:1.0万
A
Ali Talebi
H 指数:16论文数:37被引数:3,471