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Integration of CTCF loops, methylome, and transcriptome in differentiating LUHMES as a model for imprinting dynamics of the 15q11-q13 locus in human neurons Fugon, Orangel J. Gutierrez; Sharifi, Osman; Heath, Nicholas; Soto, Daniela C.; Gomez, J. Antonio; Yasui, Dag H.; Mendiola, Aron Judd P.; O'Geen, Henriette; Beitnere, Ulrika; Tomkova, Marketa; Haghani, Viktoria; Dillon, Greg; Segal, David J.; LaSalle, Janine M. 分享 收藏
Transcriptional reprogramming restores UBE3A brain-wide and rescues behavioral phenotypes in an Angelman syndrome mouse model 转录重编程在Angelman综合征小鼠模型中恢复UBE3A全脑范围并挽救行为表型 O'Geen, Henriette; Beitnere, Ulrika; Garcia, Miranda S.; Adhikari, Anna; Cameron, David L.; Fenton, Timothy A.; Copping, Nycole A.; Deng, Peter; Lock, Samantha; Halmai, Julian A. N. M.; Villegas, Isaac J.; Liu, Jiajian; Wang, Danhui; Fink, Kyle D.; Silverman, Jill L.; Segal, David J. 分享 收藏
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Unique Features of the Gut Microbiome Characterized in Animal Models of Angelman Syndrome Beitnere, Ulrika; Vilanova-Cuevas, Brayan; Christian, Sarah G.; Taylor, Clint; Berg, Elizabeth L.; Copping, Nycole A.; Dindot, Scott V.; Silverman, Jill L.; Gareau, Melanie G.; Segal, David J. 分享 收藏
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An in vivo Cell-Based Delivery Platform for Zinc Finger Artificial Transcription Factors in Pre-clinical Animal Models Deng, Peter; Halmai, Julian A. N. M.; Beitnere, Ulrika; Cameron, David; Martinez, Michele L.; Lee, Charles C.; Waldo, Jennifer J.; Thongphanh, Krista; Adhikari, Anna; Copping, Nycole; Petkova, Stela P.; Lee, Ruth D.; Lock, Samantha; Palomares, Miranda; O'Geen, Henriette; Carter, Jasmine; Gonzalez, Casiana E.; Buchanan, Fiona K. B.; Anderson, Johnathan D.; Fierro, Fernando A.; Nolta, Jan A.; Tarantal, Alice F.; Silverman, Jill L.; Segal, David J.; Fink, Kyle D. 分享 收藏
Functional rescue in an Angelman syndrome model following treatment with lentivector transduced hematopoietic stem cells Adhikari, Anna; Copping, Nycole A.; Beegle, Julie; Cameron, David L.; Deng, Peter; O'Geen, Henriette; Segal, David J.; Fink, Kyle D.; Silverman, Jill L.; Anderson, Joseph S. 分享 收藏
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Positron emission tomography imaging of novel AAV capsids maps rapid brain accumulation Seo, Jai Woong; Ingham, Elizabeth S.; Mahakian, Lisa; Tumbale, Spencer; Wu, Bo; Aghevlian, Sadaf; Shams, Shahin; Baikoghli, Mo; Jain, Poorva; Ding, Xiaozhe; Goeden, Nick; Dobreva, Tatyana; Flytzanis, Nicholas C.; Chavez, Michael; Singhal, Kratika; Leib, Ryan; James, Michelle L.; Segal, David J.; Cheng, R. Holland; Silva, Eduardo A.; Gradinaru, Viviana; Ferrara, Katherine W. 分享 收藏
Translational outcomes in a full gene deletion of ubiquitin protein ligase E3A rat model of Angelman syndrome Berg, E. L.; Pride, M. C.; Petkova, S. P.; Lee, R. D.; Copping, N. A.; Shen, Y.; Adhikari, A.; Fenton, T. A.; Pedersen, L. R.; Noakes, L. S.; Nieman, B. J.; Lerch, J. P.; Harris, S.; Born, H. A.; Peters, M. M.; Deng, P.; Cameron, D. L.; Fink, K. D.; Beitnere, U.; O'Geen, H.; Anderson, A. E.; Dindot, S., V; Nash, K. R.; Weeber, E. J.; Woehr, M.; Ellegood, J.; Segal, D. J.; Silverman, J. L. 分享 收藏
Generation of a Novel Rat Model of Angelman Syndrome with a Complete Ube3a Gene Deletion Dodge, Andie; Peters, Melinda M.; Greene, Hayden E.; Dietrick, Clifton; Botelho, Robert; Chung, Diana; Willman, Jonathan; Nenninger, Austin W.; Ciarlone, Stephanie; Kamath, Siddharth G.; Houdek, Pavel; Sumova, Alena; Anderson, Anne E.; Dindot, Scott V.; Berg, Elizabeth L.; O'Geen, Henriette; Segal, David J.; Silverman, Jill L.; Weeber, Edwin J.; Nash, Kevin R. 分享 收藏
Artificial escape from XCI by DNA methylation editing of the CDKL5 gene Halmai, Julian A. N. M.; Deng, Peter; Gonzalez, Casiana E.; Coggins, Nicole B.; Cameron, David; Carter, Jasmine L.; Buchanan, Fiona K. B.; Waldo, Jennifer J.; Lock, Samantha R.; Anderson, Johnathon D.; O'Geen, Henriette; Segal, David J.; Nolta, Jan; Fink, Kyle D. 分享 收藏
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