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H

Hiroaki Okamoto

Jichi Medical University

98H指数
1.0K论文数
4.3W被引数
收录论文 230
发表时间
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Targeting the 3C Protease of Hepatitis A Virus Subgenotype IB: Virtual Screening and Identification of Potent Lead Candidates靶向甲型肝炎病毒亚基因型IB的3C蛋白酶：虚拟筛选和强效先导化合物的鉴定
errMicroorganisms
IF4.2
err2026-09-09
err0
errOAAI
errTatsuo Kanda; Reina Sasaki-Tanaka; Hiroaki Okamoto; Shuji Terai; Cole D. Cwiklowski; Kalyan C. Nagulapalli Venkata
err分享
err收藏
Prospective Seroepidemiological Study of Hepatitis E Virus Infection in an Occupational Health-Checkup Cohort in Mie Prefecture, Japan日本三重县职业健康检查队列中戊型肝炎病毒感染的血清流行病学前瞻性研究
errHepatology Research
IF3.4
err2026-07-07
err0
PREAI
errTatsunori Nakano; Masaharu Takahashi; Yoshinori Itani; Kiriha Suzaki; Kaho Tanaka; Rune Fujimoto; Kazumoto Murata; Hiroaki Okamoto
err分享
err收藏
Elbasvir Inhibits Hepatitis E Virus Internalization and, in Combination with Ribavirin, Achieves Sustained Viral Suppression In VitroElbasvir抑制戊型肝炎病毒内化，并与利巴韦林联合使用时，在体外实现持续病毒抑制
errPathogens
IF3.3
err2026-06-05
err0
errOAAI
errPutu Prathiwi Primadharsini; Shigeo Nagashima; Masaharu Takahashi; Kazumoto Murata; Hiroaki Okamoto
err分享
err收藏
Nationwide Detection and Molecular Characterization of Hepatitis E Virus RNA in Retail Pork Meat in Japan全国范围内对日本零售猪肉中戊型肝炎病毒RNA的检测及分子特征分析
errViruses
IF3.5
err2026-05-29
err0
errOAAI
errMasaharu Takahashi; Manri Kawakami; Yukihiro Sato; Tatsunori Nakano; Jun Inoue; Junichi Koyama; Hitoshi Mizuo; Tomoya Koda; Kazumi Yamasaki; Hiroshi Okano; Akio Miyasaka; Shunji Watanabe; Norio Isoda; Tomofumi Takagi; Shinji Fujiwara; Hiroshi Ohnishi; Putu Prathiwi Primadharsini; Shigeo Nagashima; Kazumoto Murata; Hiroaki Okamoto
err分享
err收藏
Azathioprine Inhibits Hepatitis A Virus Replication In Vitro硫唑嘌呤在体外抑制甲型肝炎病毒复制
errPathogens
IF3.3
err2026-02-27
err0
errOAAI
errTatsuo Kanda; Reina Sasaki-Tanaka; Hiroyuki Abe; Takeshi Yokoo; Akira Sakamaki; Kazunao Hayashi; Hiroteru Kamimura; Kenya Kamimura; Ryota Masuzaki; Hirofumi Kogure; Hiroaki Okamoto; Shuji Terai
err分享
err收藏
Development of a hypersensitive digital ELISA system for hepatitis B core antigen乙型肝炎核心抗原超敏数字ELISA检测系统的研制
errAnalytical and Bioanalytical Chemistry
IF3.8
err2026-01-22
err0
PREAI
errYuki Nakaya; Takema Hasegawa; Yuji Hoshi; Daichi Onomura; Tomoko Yamagata; Hiroaki Okamoto; Kazumoto Murata; Megumi Kato
err分享
err收藏
Hepatitis E virus subtype 3f infections: rare but increasingly identified in Japan戊型肝炎病毒3f亚型感染：罕见但在日本被越来越多地识别
errARCHIVES OF VIROLOGY
IF2.5
err2025-11-15
err0
PREAI
errNakano, Tatsunori; Okano, Hiroshi; Uraki, Satoko; Ono, Takahiro; Shimizu, Atsuya; Takahashi, Masaharu; Nagashima, Shigeo; Murata, Kazumoto; Okamoto, Hiroaki
err分享
err收藏
Postpartum Hepatitis B Exacerbation Following Discontinuation of Nucleotide Analogue Therapy: A Case Report停用核苷类似物治疗后出现的产后乙型肝炎加重：一例病例报告
errINTERNAL MEDICINE
IF1.1
err2025-11-01
err0
PREAI
errTakada, Ryo; Shimizu, Soichiro; Yamazaki, Yuichi; Tateyama, Yumeo; Fukuchi, Toru; Murakami, Tatsuma; Tojima, Hiroki; Okamoto, Hiroaki; Uraoka, Toshio
err分享
err收藏
Zinc Acetate Inhibits Hepatitis a Virus Replication: Possible Treatment for Patients with Type A Acute-on-Chronic Liver Failure醋酸锌抑制甲型肝炎病毒复制：可能是治疗慢性肝病急性发作型患者的潜在方法
errPathogens 2025, Vol. 14, Page 882
IF3.3
err2025-09-04
err0
errOAAI
errTatsuo Kanda; Reina Sasaki-Tanaka; Hiroyuki Abe; Takeshi Yokoo; Akira Sakamaki; Kazunao Hayashi; Hiroteru Kamimura; Atsunori Tsuchiya; Ryota Masuzaki; Hirofumi Kogure; Hiroaki Okamoto; Shuji Terai
err分享
err收藏
Thermal Inactivation of Hepatitis E Virus: A Narrative Review乙型肝炎病毒的热灭活：一项叙述性综述
errVIRUSES-BASEL
IF3.5
err2025-05-14
err0
errOAAI
errKanda, Tatsuo; Okamoto, Hiroaki
err分享
err收藏
Plasmid-Based Reverse Genetics System Enabling One-Step Generation of Genotype 3 Hepatitis E Virus基于质粒的反向遗传学系统，实现基因型3型戊型肝炎病毒的一步法生成
errVIRUSES-BASEL
IF3.5
err2025-05-03
err0
errOAAI
errKobayashi, Tominari; Nishiyama, Takashi; Yamada, Kentaro; Murata, Kazumoto; Okamoto, Hiroaki
err分享
err收藏
Identification of novel antiviral host factors by functional gene expression analysis using in vitro HBV infection assay systems通过功能基因表达分析，利用体外HBV感染检测系统鉴定新型抗病毒宿主因子
errPLOS ONE
IF2.6
err2025-03-06
err0
errOAAI
errNosaka, Takuto; Naito, Tatsushi; Akazawa, Yu; Takahashi, Kazuto; Matsuda, Hidetaka; Ohtani, Masahiro; Nishizawa, Tsutomu; Okamoto, Hiroaki; Nakamoto, Yasunari
err分享
err收藏
Role of Rab13, Protein Kinase A, and Zonula Occludens-1 in Hepatitis E Virus Entry and Cell-to-Cell Spread: Comparative Analysis of Quasi-Enveloped and Non-Enveloped FormsRab13，蛋白激酶A和Zonula Occludens-1在戊型肝炎病毒进入和细胞间传播中的作用: 准包膜和非包膜形式的比较分析
errPATHOGENS
IF3.3
err2024-12-20
err0
errOAAI
errNagashima, Shigeo; Primadharsini, Putu Prathiwi; Takahashi, Masaharu; Nishiyama, Takashi; Murata, Kazumoto; Okamoto, Hiroaki
err分享
err收藏
Production and Characterization of Self-Assembled Virus-like Particles Comprising Capsid Proteins from Genotypes 3 and 4 Hepatitis E Virus (HEV) and Rabbit HEV Expressed in Escherichia coli在大肠杆菌中表达的包含来自基因型3和4的戊型肝炎病毒 (HEV) 和兔HEV的衣壳蛋白的自组装病毒样颗粒的生产和表征
errVIRUSES-BASEL
IF3.5
err2024-08-31
err1
errOAAI
errKobayashi, Tominari; Takahashi, Masaharu; Ohta, Satoshi; Hoshino, Yu; Yamada, Kentaro; Jirintai, Suljid; Primadharsini, Putu Prathiwi; Nagashima, Shigeo; Murata, Kazumoto; Okamoto, Hiroaki
err分享
err收藏
Establishment of a Hepatitis B Virus Reporter System Harboring an HiBiT-Tag in the PreS2 Region
errJOURNAL OF INFECTIOUS DISEASES
IF4.5
err2024-07-11
err1
PREAI
errNakaya, Yuki; Onomura, Daichi; Hoshi, Yuji; Yamagata, Tomoko; Morita, Hiromi; Okamoto, Hiroaki; Murata, Kazumoto
err分享
err收藏
Recent advances in hepatitis E virus research and the Japanese clinical practice guidelines for hepatitis E virus infection
errHEPATOLOGY RESEARCH
IF3.4
err2024-06-14
err2
errOAAI
errKanda, Tatsuo; Li, Tian-Cheng; Takahashi, Masaharu; Nagashima, Shigeo; Primadharsini, Putu Prathiwi; Kunita, Satoshi; Sasaki-Tanaka, Reina; Inoue, Jun; Tsuchiya, Atsunori; Nakamoto, Shingo; Abe, Ryuzo; Fujiwara, Keiichi; Yokosuka, Osamu; Suzuki, Ryosuke; Ishii, Koji; Yotsuyanagi, Hiroshi; Okamoto, Hiroaki
err分享
err收藏
The Full-Genome Analysis and Generation of an Infectious cDNA Clone of a Genotype 6 Hepatitis E Virus Variant Obtained from a Japanese Wild Boar: In Vitro Cultivation in Human Cell Lines从日本野猪获得的基因型6戊型肝炎病毒变体的全基因组分析和感染性cDNA克隆的产生: 人类细胞系的体外培养
errVIRUSES-BASEL
IF3.5
err2024-05-24
err8
errOAAI
errPrimadharsini, Putu Prathiwi; Takahashi, Masaharu; Nishizawa, Tsutomu; Sato, Yukihiro; Nagashima, Shigeo; Murata, Kazumoto; Okamoto, Hiroaki
err分享
err收藏
Recent advances in hepatitis A virus research and clinical practice guidelines for hepatitis A virus infection in Japan
errHEPATOLOGY RESEARCH
IF3.4
err2023-11-15
err4
PREAI
errKanda, Tatsuo; Sasaki-Tanaka, Reina; Ishii, Koji; Suzuki, Ryosuke; Inoue, Jun; Tsuchiya, Atsunori; Nakamoto, Shingo; Abe, Ryuzo; Fujiwara, Keiichi; Yokosuka, Osamu; Li, Tian-Cheng; Kunita, Satoshi; Yotsuyanagi, Hiroshi; Okamoto, Hiroaki
err分享
err收藏
Development of a HiBiT-tagged reporter hepatitis E virus and its utility as an antiviral drug screening platformHiBiT标记的报告戊型肝炎病毒的开发及其作为抗病毒药物筛选平台的效用
errJOURNAL OF VIROLOGY
IF3.8
err2023-09-28
err8
errOAAI
errNagashima, Shigeo; Primadharsini, Putu Prathiwi; Nishiyama, Takashi; Takahashi, Masaharu; Murata, Kazumoto; Okamoto, Hiroaki
err分享
err收藏
Three Distinct Reporter Systems of Hepatitis E Virus and Their Utility as Drug Screening Platforms戊型肝炎病毒的三个不同的报告系统及其作为药物筛选平台的效用
errVIRUSES-BASEL
IF3.5
err2023-09-23
err1
errOAAI
errPrimadharsini, Putu Prathiwi; Nagashima, Shigeo; Nishiyama, Takashi; Okamoto, Hiroaki
err分享
err收藏

研究方向

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合作学者
合作期刊
王
王军 (Jun Wang)
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Y
Yoichiro Iwakura
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O
Oliver G. Pybus
H 指数: 128 · 论文数: 615
E
Edward H. Oldfield
H 指数: 108 · 论文数: 693
T
Tooru Shimosegawa
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