Charles H. Williams - Publications, H-index & Citations

Charles H. Williams

Michigan State University

55H指数

409论文数

1.1W被引数

收录论文 50

发表时间

Zebrafish swimming towards cures: a scalable NAM platform for drug discovery 斑马鱼游向疗法：一种可扩展的NAM平台用于药物发现

Drug Discovery Today

IF7.5

2026-07-01

PREAI

Cutinho, Veona; Williams, Charles H.

Inhibition of GPR68 induces ferroptosis in diffuse intrinsic pontine gliomas 抑制GPR68可诱导弥漫性内生性脑桥胶质瘤发生铁死亡

Frontiers in Oncology

IF3.3

2026-05-13

OAAI

LR Leif R. Neitzel; AH Aaron H. Wasserman; RH Rintaro Hashizume †; CH Charles H. Williams; CC Charles C. Hong

Beyond Membrane Remodeling: Organelle Crosstalk and Convergent Pathology in Centronuclear Myopathy 超越膜重塑：中心体肌病中细胞器互作与病理汇聚

Muscles

IF0

2026-05-08

OAAI

Abolibdeh, Bana; Williams, Charles H.

Inhibition of proton sensor GPR68 suppresses endothelial dysfunction and acute lung injury caused by Staphylococcus aureus bacterial particles

FASEB JOURNAL

IF4.2

2025-02-05

OAAI

Karki, Pratap; Ke, Yunbo; Zhang, Chen-Ou; Promnares, Kamoltip; Li, Yue; Williams, Charles H.; Hong, Charles C.; Birukov, Konstantin G.; Birukova, Anna A.

Inhibition of GPR68 induces ferroptosis and radiosensitivity in diverse cancer cell types

SCIENTIFIC REPORTS

IF3.9

2025-02-03

OAAI

Neitzel, Leif R.; Fuller, Daniela T.; Cornell, Jessica; Rea, Samantha; de Aguiar Ferreira, Carolina; Williams, Charles H.; Hong, Charles C.

GPR68 Mediates Lung Endothelial Dysfunction Caused by Bacterial Inflammation and Tissue Acidification

CELLS

IF5.2

2024-12-22

OAAI

Karki, Pratap; Ke, Yunbo; Zhang, Chenou; Promnares, Kamoltip; Li, Yue; Williams, Charles H.; Hong, Charles C.; Birukov, Konstantin G.; Birukova, Anna A.

Simulating the Motion Underlying the Mechanism of Thioredoxin Reductase

ACS OMEGA

IF4.3

2024-06-25

OAAI

Zuiderweg, Erik R. P.; Case, David A.; Williams Jr, Charles H.

GPR68-ATF4 signaling is a novel prosurvival pathway in glioblastoma activated by acidic extracellular microenvironment GPR68-ATF4信号通路是酸性细胞外微环境激活的胶质母细胞瘤的一个新的促生存途径

hematology oncology

IF13.5

2024-01-31

OAAI

Williams, Charles H.; Neitzel, Leif R.; Cornell, Jessica; Rea, Samantha; Mills, Ian; Silver, Maya S.; Ahmad, Jovanni D.; Birukov, Konstantin G.; Birukova, Anna; Brem, Henry; Tyler, Betty; Bar, Eli E.; Hong, Charles C.

C5ORF51/RIMOC1-A Novel Regulator of Cardiogenesis

CIRCULATION

IF38.6

2023-11-07

PREAI

Zhang, Xueyang; Gandhi, Alay; Ratakonda, Gayatri; Williams, Charles H.; Sun, Lingfei; Li, Feng; Ward, Christopher W.; Hong, Charles C.; Gladwin, Mark T.; Yechoor, Vijay K.; Liu, Ruya

Impaired Reorganization of Centrosome Structure Underlies Human Infantile Dilated Cardiomyopathy

CIRCULATION

IF38.6

2023-04-25

OAAI

Chun, Young Wook; Miyamoto, Matthew; Williams, Charles H.; Neitzel, Leif R.; Silver-Isenstadt, Maya; Cadar, Adrian G.; Fuller, Daniela T.; Fong, Daniel C.; Liu, Hanhan; Lease, Robert; Kim, Sungseek; Katagiri, Mikako; Durbin, Matthew D.; Wang, Kuo-Chen; Feaster, Tromondae K.; Sheng, Calvin C.; Neely, M. Diana; Sreenivasan, Urmila; Cortes-Gutierrez, Marcia; Finn, Aloke V.; Schot, Rachel; Mancini, Grazia M. S.; Ament, Seth A.; Ess, Kevin C.; Bowman, Aaron B.; Han, Zhe; Bichell, David P.; Su, Yan Ru; Hong, Charles C.

Therapeutic targeting of GPR68 activated by acidic extracellular microenvironment induces ferroptosis in glioblastoma cells

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Williams, Charles H.; Neitzel, Leif R.; Cornell, Jessica; Rea, Samantha; Mills, Ian; Silver-Isenstadt, Maya; Ahmad, Jovanni D.; Brem, Henry; Tyler, Betty; Bar, Eli E.; Hong, Charles C.

Inhibition of GPR68 signaling activated downstream of the Warburg effect induces cell death and enhances radiosensitivity in diverse cancer cell types

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Neitzel, Leif R.; Lee, Han G.; Shukla, Hem; Mahmood, Javed; Williams, Charles H.; Hong, Charles C.

Surveying Cancer Cell Type Susceptibility to Ferroptotic Cell Death Via GPR68 Inhibition

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-01-01

OAAI

Kocinsky, Sona; Neitzel, Leif; Williams, Charles; Hong, Charles

The Casein kinase 1α agonist pyrvinium attenuates Wnt-mediated CK1α degradation via interaction with the E3 ubiquitin ligase component Cereblon

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-08-01

OAAI

Shen, Chen; Nayak, Anmada; Neitzel, Leif R.; Yang, Fan; Li, Bin; Williams, Charles H.; Hong, Charles C.; Ahmed, Yashi; Lee, Ethan; Robbins, David J.

GPR68 Inhibition with a Novel Group of Ogremorphin Inhibitors Upregulate Endothelial Barrier Function and Protect Against Bacterial Pathogens or Acidosis-induced Inflammation in Lung Endothelium

FASEB JOURNAL

IF4.2

2022-05-13

PREAI

Karki, Pratap; Ke, Yunbo; Williams, Charles H.; Hong, Charles C.; Birukov, Konstantin G.; Birukova, Anna A.

COMPARISON OF THE LUNG MICROBIOME IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND IN HEALTH: AN IN SILICO STUDY

THORAX

IF7.7

2021-11-08

OAAI

Short, B.; Delaney, C.; Butcher, M. C.; Litherland, G.; Williams, C.; Martin, L.; Thornbury, K.; Mackay, W. G.; Ramage, G.

The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling E3泛素连接酶组分Cereblon是Wnt信号的进化保守调节剂

NATURE COMMUNICATIONS

IF15.7

2021-09-06

OAAI

Shen, Chen; Nayak, Anmada; Neitzel, Leif R.; Adams, Amber A.; Silver-Isenstadt, Maya; Sawyer, Leah M.; Benchabane, Hassina; Wang, Huilan; Bunnag, Nawat; Li, Bin; Wynn, Daniel T.; Yang, Fan; Garcia-Contreras, Marta; Williams, Charles H.; Dakshanamurthy, Sivanesan; Hong, Charles C.; Ayad, Nagi G.; Capobianco, Anthony J.; Ahmed, Yashi; Lee, Ethan; Robbins, David J.

Risk Loci of Hypertrophic Cardiomyopathy Identified via the UK Biobank

CIRCULATION

IF38.6

2020-11-17

PREAI

Gyftopoulos, Alex; Chen, Yi-Ju; Wang, Libin; Williams, Charles H.; Chun, Young Wook; Perry, James A.; Hong, Charles C.

Cyclin Dependent Kinase Inhibitor A1 Identified as a Potential Risk Locus for Hypertrophic Cardiomyopathy

CIRCULATION RESEARCH

IF16.2

2020-07-31

PREAI

Gyftopoulos, Alex; Chen, Yi-Ju; Wang, Libin; Williams, Charles H.; Chun, Young Wook; Perry, James A.; Hong, Charles C.