José M. de Pereda

consejo superior de investigaciones cientificas and universidad de salamanca

H指数:31

被引数:5,347

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High-resolution cryo-EM structure of integrin αIIbβ3 bound to disease-causing maternal HPA-1a antibody that blocks integrin activation

整合素αIIbβ3与致病性母源HPA-1a抗体结合的高分辨率冷冻电镜结构，该抗体阻断整合素激活

Science Advances

IF12.5

2026-07-170

Maternal anti-HPA-1a antibodies block αIIbβ3 and αvβ3 integrin activation which correlates with FNAIT disease severity

母体抗HPA-1a抗体阻断αIIbβ3和αvβ3整合素激活，这与FNAIT疾病严重程度相关

Blood

IF23.1

2026-04-160

HPA-1a antibodies in FNAIT do not distinguish αvβ3 from αIIbβ3 and bind inactive integrins more strongly than active integrins

FNAIT中的HPA-1a抗体不能区分 αvβ3和 αIIbβ3，并且比活性整合素更强地结合非活性整合素

Blood

IF23.1

2025-08-140

LYP regulates SLP76 and other adaptor proteins in T cells

LYP调节T细胞中的SLP76和其他衔接蛋白

BIOLOGICAL RESEARCH

IF4.6

2024-09-280

OAAI

Pathogen-specific structural features of Candida albicans Ras1 activation complex: uncovering new antifungal drug targets

MBIO

IF4.7

2023-08-011

OAAI

Fetal and neonatal alloimmune thrombocytopenia: Current pathophysiological insights and perspectives for future diagnostics and treatment

BLOOD REVIEWS

IF5.7

2023-05-0110

OAAI

Crk proteins activate the Rap1 guanine nucleotide exchange factor C3G by segregated adaptor-dependent and -independent mechanisms

CELL COMMUNICATION AND SIGNALING

IF8.9

2023-02-037

OAAI

PSTPIP1-LYP phosphatase interaction: structural basis and implications for autoinflammatory disorders

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2022-02-127

OAAI

Regulation of hemidesmosome dynamics and cell signaling by integrin α6β4

JOURNAL OF CELL SCIENCE

IF3.6

2021-09-153

EGFR-dependent tyrosine phosphorylation of integrin β4 is not required for downstream signaling events in cancer cell lines

SCIENTIFIC REPORTS

IF3.9

2021-04-210

OAAI

Mechanisms of autoregulation of C3G, activator of the GTPase Rap1, and its catalytic deregulation in lymphomas

SCIENCE SIGNALING

IF6.6

2020-09-0112

OAAI

A mutation in p62 protein (p. R321C), associated to Paget's disease of bone, causes a blockade of autophagy and an activation of NF-kB pathway

BONE

IF3.6

2020-04-0115

PREAI

C3G, through its GEF activity, induces megakaryocytic differentiation and proplatelet formation

CELL COMMUNICATION AND SIGNALING

IF8.9

2018-12-1920

OAAI

Ferredoxin-linked flavoenzyme defines a family of pyridine nucleotide-independent thioredoxin reductases

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-12-0313

OAAI

Unprecedented pathway of reducing equivalents in a diflavin-linked disulfide oxidoreductase

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-11-1312

A nucleotide-controlled conformational switch modulates the activity of eukaryotic IMP dehydrogenases

SCIENTIFIC REPORTS

IF3.9

2017-06-0145

OAAI

A New Member of the Thioredoxin Reductase Family from Early Oxygenic Photosynthetic Organisms

MOLECULAR PLANT

IF24.1

2017-01-0116

OAAI

The Structure of the Plakin Domain of Plectin Reveals an Extended Rod-like Shape

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2016-09-0136

OAAI

Guanine nucleotide binding to the Bateman domain mediates the allosteric inhibition of eukaryotic IMP dehydrogenases

NATURE COMMUNICATIONS

IF15.7

2015-11-1269

OAAI

Increased riboflavin production by manipulation of inosine 5'-monophosphate dehydrogenase in Ashbya gossypii

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

IF4.3

2015-07-0732

PREAI

José M. de Pereda

个人简介

教育背景

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