未登录Targeting therapy-resistant SOX9-positive cells with a cytotoxic gene therapy in glioblastoma使用细胞毒性基因疗法靶向治疗胶质母细胞瘤中具有治疗抵抗性的SOX9阳性细胞
Vikstrom, Elin; Lin, Tong; Kissa, Eleftheria; Holmberg, Karl; Bergstrom, Tobias; Rosen, Gabriela; Badillo-Godinez, Oscar; Dalmo, Erika; Essand, Magnus; Westermark, Bengt; Hellstrom, Mats; Giraud, Geraldine; Rendo, Veronica; Swartling, Fredrik .png)
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收藏分享 收藏 分享 收藏 分享 收藏 PRRX1 induced by BMP signaling decreases tumorigenesis by epigenetically regulating glioma-initiating cell properties via DNA methyltransferase 3ATanabe, Ryo; Miyazono, Kohei; Todo, Tomoki; Saito, Nobuhito; Iwata, Caname; Komuro, Akiyoshi; Sakai, Satoshi; Raja, Erna; Koinuma, Daizo; Morikawa, Masato; Westermark, Bengt; Heldin, Carl-Henrik 分享 收藏 A human cell type similar to murine central nervous system perivascular fibroblastsLiu, Jianping; He, Liqun; Muhl, Lars; Mocci, Giuseppe; Gustavsson, Sonja; Buyandelger, Byambajav; Vanlandewijck, Michael; Betsholtz, Christer; Westermark, Bengt; Andrae, Johanna 分享 收藏 分享 收藏 BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cellsCancer, Matko; Drews, Lisa F.; Bengtsson, Johan; Bolin, Sara; Rosen, Gabriela; Westermark, Bengt; Nelander, Sven; Forsberg-Nilsson, Karin; Uhrbom, Lene; Weishaupt, Holger; Swartling, Fredrik J. 分享 收藏 Mesenchymal transition and increased therapy resistance of glioblastoma cells is related to astrocyte reactivity胶质母细胞瘤细胞的间质转化和治疗抵抗增加与星形胶质细胞反应性有关Niklasson, Mia; Bergstrom, Tobias; Jarvius, Malin; Sundstrom, Anders; Nyberg, Frida; Haglund, Caroline; Larsson, Rolf; Westermark, Bengt; Segerman, Bo; Segerman, Anna 分享 收藏 Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumorsKaffes, Ioannis; Szulzewsky, Frank; Chen, Zhihong; Herting, Cameron J.; Gabanic, Ben; Vega, Jose E. Velazquez; Shelton, Jennifer; Switchenko, Jeffrey M.; Ross, James L.; McSwain, Leon F.; Huse, Jason T.; Westermark, Bengt; Nelander, Sven; Forsberg-Nilsson, Karin; Uhrbom, Lene; Maturi, Naga Prathyusha; Cimino, Patrick J.; Holland, Eric C.; Kettenmann, Helmut; Brennan, Cameron W.; Brat, Daniel J.; Hambardzumyan, Dolores 分享 收藏 分享 收藏 分享 收藏 Targeting of a mesenchymal profile in order to sensitize multitherapy resistant glioblastoma clonesNiklasson, Mia; Jarvius, Malin; Haglund, Caroline; Chantzi, Efthymia; Bergstrom, Tobias; Nyberg, Frida; Hermansson, Annika; Fryknas, Marten; Gustafsson, Mats; Segerman, Bo; Larsson, Rolf; Westermark, Bengt; Segerman, Anna 分享 收藏 Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal TransitionSegerman, Anna; Niklasson, Mia; Haglund, Caroline; Bergstrom, Tobias; Jarvius, Malin; Xie, Yuan; Westermark, Ann; Sonmez, Demet; Hermansson, Annika; Kastemar, Marianne; Naimaie-Ali, Zeinab; Nyberg, Frida; Berglund, Malin; Sundstrom, Magnus; Hesselager, Goran; Uhrbom, Lene; Gustafsson, Mats; Larsson, Rolf; Fryknas, Marten; Segerman, Bo; Westermark, Bengt 分享 收藏 分享 收藏 ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cellsWee, Boyoung; Pietras, Alexander; Ozawa, Tatsuya; Bazzoli, Elena; Podlaha, Ondrej; Antczak, Christophe; Westermark, Bengt; Nelander, Sven; Uhrbom, Lene; Forsberg-Nilsson, Karin; Djaballah, Hakim; Michor, Franziska; Holland, Eric C. 分享 收藏 GBM exhibits phenotypic microheterogeneity and harbors pre-existing multi resistant clones with a mesenchymal transition signatureSegerman, Anna; Niklasson, Maria; Haglund, Caroline; Bergstrom, Tobias; Jarvius, Malin; Xie, Yuan; Simov, Demet Caglayan; Hermansson, Annika; Kastemar, Marianne; Naimaie-Ali, Zeinab; Berglund, Malin; Westermark, Ann; Sundstrom, Magnus; Hesselager, Goran; Uhrbom, Lene; Gustafsson, Mats; Larsson, Rolf; Fryknas, Marten; Segerman, Bo; Westermark, Bengt 分享 收藏 Simultaneous Multiplexed Measurement of RNA and Proteins in Single CellsDarmanis, Spyros; Gallant, Caroline Julie; Marinescu, Voichita Dana; Niklasson, Mia; Segerman, Anna; Flamourakis, Georgios; Fredriksson, Simon; Assarsson, Erika; Lundberg, Martin; Nelander, Sven; Westermark, Bengt; Landegren, Ulf 分享 收藏 The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular SubtypesXie, Yuan; Bergstrom, Tobias; Jiang, Yiwen; Johansson, Patrik; Marinescu, Voichita Dana; Lindberg, Nanna; Segerman, Anna; Wicher, Grzegorz; Niklasson, Mia; Baskaran, Sathishkumar; Sreedharan, Smitha; Everlien, Isabelle; Kastemar, Marianne; Hermansson, Annika; Elfineh, Lioudmila; Libard, Sylwia; Holland, Eric Charles; Hesselager, Goran; Alafuzoff, Irina; Westermark, Bengt; Nelander, Sven; Forsberg-Nilsson, Karin; Uhrbom, Lene 分享 收藏 分享 收藏 
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