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Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease models Kataura, Tetsushi; Sedlackova, Lucia; Sun, Congxin; Kocak, Gamze; Wilson, Niall; Banks, Peter; Hayat, Faisal; Trushin, Sergey; Trushina, Eugenia; Maddocks, Oliver D. K.; Oblong, John E.; Miwa, Satomi; Imoto, Masaya; Saiki, Shinji; Erskine, Daniel; Migaud, Marie E.; Sarkar, Sovan; Korolchuk, Viktor I. 分享 收藏
The glutamate/aspartate transporter EAAT1 is crucial for T-cell acute lymphoblastic leukemia proliferation and survival Stanulovic, Vesna S.; Al Omair, Shorog; Reed, Michelle A. C.; Roberts, Jennie; Potluri, Sandeep; Fulton-Ward, Taylor; Gudgeon, Nancy; Bishop, Emma L.; Roels, Juliette; Perry, Tracey A.; Sarkar, Sovan; Pratt, Guy; Taghon, Tom; Dimeloe, Sarah; Guenther, Ulrich L.; Ludwig, Christian; Hoogenkamp, Maarten 分享 收藏
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Depletion of WFS1 compromises mitochondrial function in hiPSC-derived neuronal models of Wolfram syndrome Zatyka, Malgorzata; Rosenstock, Tatiana R.; Sun, Congxin; Palhegyi, Adina M.; Hughes, Georgina W.; Lara-Reyna, Samuel; Astuti, Dewi; di Maio, Alessandro; Sciauvaud, Axel; Korsgen, Miriam E.; Stanulovic, Vesna; Kocak, Gamze; Rak, Malgorzata; Pourtoy-Brasselet, Sandra; Winter, Katherine; Varga, Thiago; Jarrige, Margot; Polveche, Helene; Correia, Joao; Frickel, Eva-Maria; Hoogenkamp, Maarten; Ward, Douglas G.; Aubry, Laetitia; Barrett, Timothy; Sarkar, Sovan 分享 收藏
NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency NAD耗竭介导自噬缺乏的人神经元的细胞毒性 Sun, Congxin; Seranova, Elena; Cohen, Malkiel A.; Chipara, Miruna; Roberts, Jennie; Astuti, Dewi; Palhegyi, Adina M.; Acharjee, Animesh; Sedlackova, Lucia; Kataura, Tetsushi; Otten, Elsje G.; Panda, Prashanta K.; Lara-Reyna, Samuel; Korsgen, Miriam E.; Kauffman, Kevin J.; Huerta-Uribe, Alejandro; Zatyka, Malgorzata; Silva, Luiz F. S. E.; Torresi, Jorge; Zhang, Shupei; Hughes, Georgina W.; Ward, Carl; Kuechler, Erich R.; Cartwright, David; Trushin, Sergey; Trushina, Eugenia; Sahay, Gaurav; Buganim, Yosef; Lavery, Gareth G.; Gsponer, Joerg; Anderson, Daniel G.; Frickel, Eva-Maria; Rosenstock, Tatiana R.; Barrett, Timothy; Maddocks, Oliver D. K.; Tennant, Daniel A.; Wang, Haoyi; Jaenisch, Rudolf; Korolchuk, Viktor I.; Sarkar, Sovan 分享 收藏
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Autophagy promotes cell survival by maintaining NAD levels 自噬通过维持NAD水平促进细胞存活 Kataura, Tetsushi; Sedlackova, Lucia; Otten, Elsje G.; Kumari, Ruchika; Shapira, David; Scialo, Filippo; Stefanatos, Rhoda; Ishikawa, Kei-ichi; Kelly, George; Seranova, Elena; Sun, Congxin; Maetzel, Dorothea; Kenneth, Niall; Trushin, Sergey; Zhang, Tong; Trushina, Eugenia; Bascom, Charles C.; Tasseff, Ryan; Isfort, Robert J.; Oblong, John E.; Miwa, Satomi; Lazarou, Michael; Jaenisch, Rudolf; Imoto, Masaya; Saiki, Shinji; Papamichos-Chronakis, Manolis; Manjithaya, Ravi; Maddocks, Oliver D. K.; Sanz, Alberto; Sarkar, Sovan; Korolchuk, Viktor I. 分享 收藏
Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity (vol 5, e11058, 201226) Carroll, Bernadette; Maetzel, Dorothea; Maddocks, Oliver D. K.; Otten, Gisela; Ratcliff, Matthew; Smith, Graham R.; Dunlop, Elaine A.; Passos, Joao F.; Davies, Owen Richard; Jaenisch, Rudolf; Tee, Andrew R.; Sarkar, Sovan; Korolchuk, Viktor I. 分享 收藏
Trehalose limits opportunistic mycobacterial survival during HIV co-infection by reversing HIV-mediated autophagy block Sharma, Vartika; Makhdoomi, Muzamil; Singh, Lakshyaveer; Kumar, Purnima; Khan, Nabab; Singh, Sarman; Verma, H. N.; Luthra, Kalpana; Sarkar, Sovan; Kumar, Dhiraj 分享 收藏
Autophagy modulator scoring system: a user-friendly tool for quantitative analysis of methodological integrity of chemical autophagy modulator studies Dong, Yu; Hu, Yuanjia; Sarkar, Sovan; Zong, Wei-Xing; Li, Min; Feng, Du; Song, Ju-Xian; Medina, Diego L.; Tan, Jieqiong; Zhang, Zhuohua; Yue, Zhenyu; Lu, Jia-Hong 分享 收藏
Homologous recombination repair intermediates promote efficient de novo telomere addition at DNA double-strand breaks Dave, Anoushka; Pai, Chen-Chun; Durley, Samuel C.; Hulme, Lydia; Sarkar, Sovan; Wee, Boon-Yu; Prudden, John; Tinline-Purvis, Helen; Cullen, Jason K.; Walker, Carol; Watson, Adam; Carr, Antony M.; Murray, Johanne M.; Humphrey, Timothy C. 分享 收藏
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Resistance exercise initiates mechanistic target of rapamycin (mTOR) translocation and protein complex co-localisation in human skeletal muscle Song, Zhe; Moore, Daniel R.; Hodson, Nathan; Ward, Carl; Dent, Jessica R.; O'Leary, Mary F.; Shaw, Andrew M.; Hamilton, D. Lee; Sarkar, Sovan; Gangloff, Yann-Gael; Hornberger, Troy A.; Spriet, Lawrence L.; Heigenhauser, George J.; Philp, Andrew 分享 收藏
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