Juan C. Sáez - Publications, H-index & Citations

Juan C. Sáez

universidad de valparaíso

74H指数

303论文数

1.9W被引数

收录论文 108

发表时间

Large-Pore Channels at the Maternal–Fetal Interface: Progress and Open Research Avenues 母胎界面上的大孔通道：进展与待研究课题

Biology-Basel

IF3.5

2026-09-08

OAAI

José L. Vega; Antonia Moral; Camila Gutiérrez; Juan C. Sáez

High Activity of Hemichannels Permeable to Calcium Ions Leads to ROS Generation and Reduced Cell Viability 钙离子通透性半通道的高活性导致ROS生成和细胞活力下降

International Journal of Molecular Sciences

IF4.9

2026-02-10

OAAI

Walter Vásquez; Carolina Urrutia; Ximena López; Luis A. Cea; José L. Vega; Viviana M. Berthoud; Juan C. Sáez

Oral administration of boldine reduces neuropathic pain After spared nerve injury in female mice

PAIN Reports

IF3.1

2026-01-09

OAAI

Pan, Jiangpinga; Toro, Carlos A.a, b, c; Chow, Christinea; Duarte, Yorleyd, e; Sáez, Juan C.e; Cardozo, Christopher P.a, b, f; Zhao, Weia, b

Boldo leaves reduce seizures, neuroinflammation, and hemichannel activity in a murine model of chronic epilepsy 鼠李茶（Boldo leaves）可减少慢性癫痫小鼠模型中的癫痫发作、神经炎症和缝隙连接通道活性。

Biological Research

IF4.6

2025-12-07

OAAI

Claudia García-Rodríguez; Carolina Flores-Muñoz; Paola Fernández; Marcela Escobar; Álvaro O. Ardiles; Ana M. Cardenas; Juan C. Sáez

Boldo Restores Vascularization and Reduces Skeletal Muscle Inflammation in Symptomatic Mice with Dysferlinopathy 博尔多（Boldo）恢复血管生成并减少肌营养不良相关症状小鼠骨骼肌炎症

International Journal of Molecular Sciences 2025, Vol. 26, Page 9945

IF0

2025-10-13

OAAI

Walter Vásquez; Felipe Troncoso; Andrea Lira; Carlos Escudero; Juan C. Sáez

Boldine as a neuroprotective agent against motor neuron degeneration in models of amyotrophic lateral sclerosis Boldine作为神经保护剂，用于对抗运动神经元退行性变，在肌萎缩侧索硬化症模型中。

Frontiers in Cellular Neuroscience

IF4

2025-09-27

OAAI

Carlos A. Toro†‡; Wei Zhao†‡; Patricio Garcia Silva†; Daniela Retamal-Santibáñez; Fabiola Rojas; Jiangping Pan; Nicholas Johnson‡; Yorley Duarte‡; Christopher P. Cardozo‡; Juan C. Sáez; Brigitte van Zundert‡

Connexin and Pannexin Hemichannels: Broad-Spectrum Players in Neuroinflammatory Signaling 连接蛋白和泛连接蛋白半通道：神经炎症信号传导中的广谱参与者

Journal of Neurochemistry

IF4

2025-09-16

PREAI

Juan C. Sáez; Francisco J. Ocaranza; Juan Prieto-Villalobos; Juan A. Orellana

Connexin hemichannels and early atrophic signaling in muscle during sepsis

FRONTIERS IN PHYSIOLOGY

IF3.4

2025-02-24

OAAI

Balboa, Elisa; Saavedra, Fujiko; Cea, Luis A.; Vargas, Anibal A.; Regueira, Tomas; Saez, Juan C.

Poly (I:C)-induced inflammation requires the activation of toll-like receptor 3/Ca2+/CaMKII/pannexin 1-dependent signaling Poly (I:C)诱导的炎症需要Toll样受体3/Ca2+/CaMKII/连接蛋白1依赖性信号通路的激活。

THERANOSTICS

IF13.3

2025-01-20

OAAI

Salgado, Magdiel; Sepulveda-Arriagada, Vania; Konar-Nie, Macarena; Garcia-Robles, Maria A.; Saez, Juan C.

Lack of canonical activities of connexins in highly aggressive human prostate cancer cells

BIOLOGICAL RESEARCH

IF4.6

2024-12-19

OAAI

Asencio, Catalina; Veliz, Loreto; Flores-Faundez, Emilia; Azocar, Lorena; Echeverria, Carolina E.; Torres-Estay, Veronica; Orellana, Viviana; Ramirez-Santelices, Catalina; Sotomayor, Paula; Cancino, Jorge; Kerr, Bredford; Fernandez-Olivares, Ainoa; Retamal, Mauricio A.; Saez, Juan C.; Godoy, Alejandro S.

Pathophysiological role of connexin and pannexin hemichannels in neuromuscular disorders 缝隙连接蛋白和泛连接蛋白半通道在神经肌肉疾病中的病理生理学作用

physiology

IF0

2024-08-22

PREAI

Walter Vásquez; Carlos A. Toro; Christopher P. Cardozo; Luis A. Cea; Juan C. Sáez

Inhibition of astroglial hemichannels prevents synaptic transmission decline during spreading depression 抑制星形胶质半通道可防止扩散抑制期间突触传递下降

BIOLOGICAL RESEARCH

IF4.6

2024-06-12

OAAI

Tichauer, Juan E.; Lira, Matias; Cerpa, Waldo; Orellana, Juan A.; Saez, Juan C.; Rovegno, Maximiliano

Ca2+ permeation through C-terminal cleaved, but not full- length human Pannexin1 hemichannels, mediates cell death

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-06-11

OAAI

Salgado, Magdiel; Marquez-Miranda, Valeria; Ferrada, Luciano; Rojas, Maximiliano; Poblete-Flores, Gonzalo; Gonzalez-Nilo, Fernando D.; Ardiles, Alvaro O.; Saez, Juan C.

Autocrine activation of P2X7 receptors mediates catecholamine secretion in chromaffin cells

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2024-04-28

PREAI

Maldifassi, Maria Constanza; Guerra-Fernandez, Maria Jose; Ponce, Daniela; Alfonso-Bueno, Samuel; Maripillan, Jaime; Vielma, Alex H.; Baez-Matus, Ximena; Marengo, Fernando D.; Acuna-Castillo, Claudio; Saez, Juan C.; Martinez, Agustin D.; Cardenas, Ana M.

Cx43 hemichannels and panx1 channels contribute to ethanol-induced astrocyte dysfunction and damage

BIOLOGICAL RESEARCH

IF4.6

2024-04-04

OAAI

Gomez, Gonzalo I.; Alvear, Tanhia F.; Roa, Daniela A.; Farias-Pasten, Arantza; Vergara, Sergio A.; Mellado, Luis A.; Martinez-Araya, Claudio J.; Prieto-Villalobos, Juan; Garcia-Rodriguez, Claudia; Sanchez, Natalia; Saez, Juan C.; Ortiz, Fernando C.; Orellana, Juan A.

Michael V. L. Bennett (1931 to 2023): A world- renowned authority in the field of electrical synapses in the nervous system

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-02-26

OAAI

Saez, Juan C.

The connexin hemichannel inhibitor D4 produces rapid antidepressant-like effects in mice

JOURNAL OF NEUROINFLAMMATION

IF10.1

2023-08-20

OAAI

Li, Huanhuan; Guo, Anni; Salgado, Magdiel; Saez, Juan C.; Lau, Chunyue Geoffrey

Antiproliferative effect of boldine on neural progenitor cells and on glioblastoma cells

FRONTIERS IN NEUROSCIENCE

IF3.2

2023-08-16

OAAI

Jimenez-Madrona, Enrique; Morado-Diaz, Camilo J.; Talaveron, Rocio; Tabernero, Arantxa; Pastor, Angel M.; Saez, Juan C.; Matarredona, Esperanza R.

Unnexin is a protein subunit of a large- pore channel expressed by unicellular organisms

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-07-24

OAAI

Guiza, Juan; Solis, Francisco; Valenzuela, Bernardita; Arancibia, Duxan; Zamorano, Pedro; Gonzalez, Jorge; Saavedra, Jonathan; Neely, Alan; Salgado, Magdiel; Martinez, Agustin D.; Saez, Juan C.; Vega, Jose L.

Boldine modulates glial transcription and functional recovery in a murine model of contusion spinal cord injury

FRONTIERS IN CELLULAR NEUROSCIENCE

IF4

2023-06-21

OAAI

Toro, Carlos A.; Johnson, Kaitlin; Hansen, Jens; Siddiq, Mustafa M.; Vasquez, Walter; Zhao, Wei; Graham, Zachary A.; Saez, Juan C.; Iyengar, Ravi; Cardozo, Christopher P.

研究方向