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M

Mark Roest

department of platelet pathophysiology

33H指数
175论文数
4.1K被引数
收录论文 67
发表时间
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Thrombin dynamics and clinical events in cirrhosis: low prothrombin conversion predicts bleeding risk凝血酶动力学与肝硬化临床事件：低凝血酶原转化率预测出血风险
errFrontiers in Cell and Developmental Biology
IF4.3
err2026-09-02
err0
errOAAI
errRA Ruth Anne Laura Willems †; AZ Alberto Zanetto †; EC Elena Campello; JK Joke Konings; CB Cristiana Bulato; MK Matthijs Kramer; FP Francesco Paolo Russo; MR Mark Roest; MS Marco Senzolo; PB Patrizia Burra; HT Hugo ten Cate; JD Judith de Vos-Geelen; BD Bas de Laat; PS Paolo Simioni; RD Romy de Laat-Kremers
err分享
err收藏
HMB-002: A Monovalent Antibody that Elevates Circulating VWF and FVIII Levels for Treatment of Von Willebrand Disease
errBlood Advances
IF7.1
err2026-01-29
err0
errOAAI
errMattias Häger; Minka Zivkovic; Prafull S. Gandhi; Caroline Rasmussen; Cécile Bonvoisin; Rane A. Harrison; Emil Poulsen; Dana Huskens; Mark Roest; Fortunato Ferrara; Anais Naretto; Lionel Renaud; Ole H. Olsen; Nicolas O. Eskesen; Lars Holten-Andersen; Ruthvik Malladi; Catherine J. Rea; Benny Sørensen; Rolf T. Urbanus; Henrik Østergaard
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Effects of Continuation versus Interruption of Oral Anticoagulation during TAVI on Hemostasis Function继续与中断经皮主动脉瓣置换术期间口服抗凝治疗对止血功能的影响
errJournal of Thrombosis and Haemostasis
IF5
err2025-12-03
err0
PREAI
errDirk Jan van Ginkel; Hendrik Stragier; Willem L. Bor; Liesbeth Rosseel; Joke Konings; Marisa Ninivaggi; Ilaria de Simone; Dana Huskens; Mark Roest; Iris van Lenthe; Daniel C. Overduin; Errol W. Aarnink; Maxim J.P. Rooijakkers; Joyce Peper; Jorn Brouwer; Vincent J. Nijenhuis; Benno J.W.M. Rensing; Leo Timmers; Martin J. Swaans; Chris M. Hackeng
err分享
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Elevated levels of (active) von Willebrand factor during anticoagulation are associated with early recurrence of venous thromboembolism抗凝期间升高的(活性)冯·维勒布兰德因子水平与静脉血栓栓塞症的早期复发相关
errJournal of Thrombosis and Haemostasis
IF5
err2025-05-13
err0
errOAAI
errGeke C. Poolen; Rolf T. Urbanus; Mark Roest; Geert–Jan Geersing; Bas de Laat; Roger E.G. Schutgens
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Patients with cirrhosis have a disbalance between coagulation and fibrinolysis resulting in a prothrombotic phenotype肝硬化患者存在凝血与纤溶之间的失衡，导致血栓前表型。
errJournal of Thrombosis and Haemostasis
IF5
err2025-03-06
err0
PREAI
errRuth Anne Laura Willems; Alberto Zanetto; Elena Campello; Ilaria de Simone; Cristiana Bulato; Joke Konings; Matthijs Kramer; Samia Tufaha; Francesco Paolo Russo; Marco Senzolo; Patrizia Burra; Hugo ten Cate; Judith de Vos-Geelen; Mark Roest; Paolo Simioni; Bas de Laat; Dana Huskens
err分享
err收藏
High Prevalence of Acquired Platelet Secretion Defects in Multiple Myeloma多发性骨髓瘤中获得的血小板分泌缺陷的高发病率
errHAMOSTASEOLOGIE
IF2.4
err2025-02-11
err0
errOAAI
errSwieringa, Frauke; Sang, Yaqiu; Remijn, Jasper A.; Fijnheer, Rob; Korporaal, Suzanne J. A.; Urbanus, Rolf T.; Huskens, Dana; Konings, Joke; Li, Li; de Laat, Bas; Roest, Mark
err分享
err收藏
No correlation between thrombin generation and emicizumab levels: implications for monitoring emicizumab therapy
errRESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS
IF3.4
err2025-01-01
err0
errOAAI
errvan der Zwet, Konrad; Roest, Mark; Huskens, Dana; Schutgens, Roger E. G.; Vulpen, Lize F. D. van; Fischer, Kathelijn; Urbanus, Rolf T.
err分享
err收藏
Functionally distinct anticoagulant mechanisms of endothelial cells
errTHROMBOSIS RESEARCH
IF3.4
err2024-12-01
err0
PREAI
errSchoenichen, Claudia; Sun, Siyu; Middelveld, Harmen; Huskens, Dana; de Groot, Philip G.; Heemskerk, Johan W. M.; Roest, Mark; de Laat, Bas
err分享
err收藏
Low thrombin inactivation capacity is associated with an increased risk of recurrent ischemic events after ischemic stroke at a young age
errJOURNAL OF THROMBOSIS AND HAEMOSTASIS
IF5
err2024-12-01
err0
errOAAI
errSpiegelenberg, Janneke P.; De Laat-Kremers, Romy; Roest, Mark; de Laat, Bas; van Gelder, Marleen M. H. J.; Tuladhar, Anil M.; Middeldorp, Saskia; de Leeuw, Frank-Erik; Leentjens, Jenneke
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Evaluating the Clinical Relevance of Thrombin Generation Potential during Emicizumab Therapy评估emicizumab治疗期间凝血酶生成潜能的临床相关性
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errvan der Zwet, Konrad; Roest, Mark; Huskens, Dana; Van Beers, Eduard J.; Fischer, Kathelijn; Van Vulpen, Lize Fie Ditteke; Schutgens, Roger E. G.; Urbanus, Rolf T.
err分享
err收藏
Plasma kallikrein supports FXII-independent thrombin generation in mouse whole blood
errBLOOD ADVANCES
IF7.1
err2024-06-12
err0
errOAAI
errWan, Jun; Dhrolia, Sophia; Kasthuri, Rohan R.; Prokopenko, Yuriy; Ilich, Anton; Saha, Prakash; Roest, Mark; Wolberg, Alisa S.; Key, Nigel S.; Pawlinski, Rafal; Bendapudi, Pavan K.; Mackman, Nigel; Grover, Steven P.
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Endogenous thrombin potential and time-dependent thrombingeneration parameters are independent risk factors formortality in the general population内源性凝血酶潜能和时间依赖性血小板生成参数是普通人群的独立危险因素
errJOURNAL OF THROMBOSIS AND HAEMOSTASIS
IF5
err2024-06-01
err0
PREAI
errde Laat-Kremers, Romy; Costanzo, Simona; Roest, Mark; De Curtis, Amalia; Huskens, Dana; Di Castelnuovo, Augusto; Ninivaggi, Marisa; Cerletti, Chiara; Donati, Maria Benedetta; de Laat, Bas; Iacoviello, Licia
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Altered whole blood thrombin generation and hyperresponsive platelets in patients with pancreatic cancer
errJOURNAL OF THROMBOSIS AND HAEMOSTASIS
IF5
err2024-04-01
err1
PREAI
errWillems, Ruth Anne Laura; Konings, Joke; Huskens, Dana; Middelveld, Harmen; Pepels-Aarts, Nicol; Verbeet, Lisa; de Groot, Phillip Gerrit; Heemskerk, Johan Willem Marie; ten Cate, Hugo; de Vos-Geelen, Judith; de Laat, Bas; Roest, Mark
err分享
err收藏
Exercise and hypoxia-induced hypercoagulability is counterbalanced in women in part by decreased platelet reactivity
errTHROMBOSIS RESEARCH
IF3.4
err2024-02-01
err2
PREAI
errNinivaggi, M.; Swieringa, F.; Middelveld, H.; Schmalschlager, V.; Roest, M.; de Laat-Kremers, R.; de Laat, B.
err分享
err收藏
Whole blood thrombin generation shows a significant hypocoagulable state in patients with decompensated cirrhosis
errJOURNAL OF THROMBOSIS AND HAEMOSTASIS
IF5
err2024-02-01
err12
PREAI
errZanetto, Alberto; Campello, Elena; Bulato, Cristiana; Willems, Ruth; Konings, Joke; Roest, Mark; Gavasso, Sabrina; Nuozzi, Giorgia; Toffanin, Serena; Zanaga, Paola; Burra, Patrizia; Russo, Francesco Paolo; Senzolo, Marco; de Laat, Bas; Simioni, Paolo
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err收藏
yWhole blood thrombin generation improves the understanding of cirrhotic coagulopathy and predicts clinical outcomes in patients with cirrhosis: a prospective cohort study
errDIGESTIVE AND LIVER DISEASE
IF3.8
err2024-02-01
err0
PREAI
errZanetto, A.; Campello, E.; Bulato, C.; Willems, R.; Konings, J.; Roest, M.; Gavasso, S.; Nuozzi, G.; Toffanin, S.; Zanaga, P.; Burra, P.; Russo, F. P.; de Laat, B.; Simioni, P.; Senzolo, M.
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Cellular Components Contributing to the Development of Venous Thrombosis in Patients with Pancreatic Cancer
errSEMINARS IN THROMBOSIS AND HEMOSTASIS
IF4.1
err2023-12-04
err3
PREAI
errWillems, Ruth Anne Laura; Biesmans, Charlotte; Campello, Elena; Simioni, Paolo; de Laat, Bas; de Vos-Geelen, Judith; Roest, Mark; ten Cate, Hugo
err分享
err收藏
Crucial roles of red blood cells and platelets in whole blood thrombin generation
errBLOOD ADVANCES
IF7.1
err2023-11-02
err9
errOAAI
errSun, Siyu; Campello, Elena; Zou, Jinmi; Konings, Joke; Huskens, Dana; Wan, Jun; Fernandez, Delia I.; Reutelingsperger, Chris P. M.; ten Cate, Hugo; Toffanin, Serena; Bulato, Cristiana; Groot, Philip G. de; de Laat, Bas; Simioni, Paolo; Heemskerk, Johan W. M.; Roest, Mark
err分享
err收藏
High-throughput assessment identifying major platelet Ca2+entry pathways via tyrosine kinase-linked and G protein-coupled receptors
errCELL CALCIUM
IF4
err2023-06-01
err9
errOAAI
errCheung, Hilaire Yam Fung; Zou, Jinmi; Tantiwong, Chukiat; Fernandez, Delia I.; Huang, Jingnan; Ahrends, Robert; Roest, Mark; Cavill, Rachel; Gibbins, Jon; Heemskerk, Johan W. M.
err分享
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A novel mouse whole blood thrombin generation assay sensitive to FXI- and FIX-mediated amplification of coagulation
errBLOOD ADVANCES
IF7.1
err2023-05-09
err4
errOAAI
errWan, Jun; Tanratana, Pansakorn; Roest, Mark; Gruber, Andras; Pawlinski, Rafal; Wolberg, Alisa S.; Mackman, Nigel; Grover, Steven P.
err分享
err收藏

研究方向

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