Yi‐Jen Chen - Publications, H-index & Citations

Yi‐Jen Chen

taipei medical university

46H指数

293论文数

9.0K被引数

收录论文 101

发表时间

Vericiguat, a soluble guanylate cyclase stimulator, regulates heart failure–enhanced atrial and pulmonary vein arrhythmogenesis 维利沙新，一种可溶性鸟苷酸环化酶刺激剂，调控心力衰竭增强的心房和肺静脉心律失常发生

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2026-06-17

OAAI

Chao-Shun Chan; Yen-Yu Lu; Fong-Jhih Lin; Yao-Chang Chen; Satoshi Higa; Yu-Hsun Kao; Shih-Ann Chen; Yi-Jen Chen

Bradykinin Modulates Endothelin-1–Enhanced and Monocrotaline-induced Pulmonary Arterial Hypertension–associated Arrhythmogenesis in Rabbit Right Ventricular Outflow Tract via a Nitric Oxide-dependent Pathway 缓激肽通过一氧化氮依赖途径调节内皮素-1增强和 monocrotaline 诱导的肺动脉高压相关的心律失常发生，在兔右心室流出道中的作用

European Journal of Pharmacology

IF4.7

2026-04-24

PREAI

Yen-Yu Lu; Fong-Jhih Lin; Yao-Chang Chen; Chye-Gen Chin; Chao-Shun Chan; Satoshi Higa; Yi-Jen Chen

ZFHX3 Knockdown Enhances Metabolic Distress in Atrial Myocytes Through Mitochondrial and Calcium Dysregulation: Mitigation by Trimetazidine ZFHX3敲低通过线粒体和钙离子失调增强心房肌细胞代谢应激：曲美他嗪的缓解作用

International Journal of Molecular Sciences

IF4.9

2026-03-03

OAAI

Baigalmaa Lkhagva; Shuen-Hsin Liu; Satoshi Higa; Yu-Hsun Kao; Yi-Jen Chen

Calcitriol deficiency reduces myocardial ATP production with disturbed mitochondrial dynamics and increased uncoupling protein 2 expression 钙三醇缺乏会减少心肌ATP的产生，伴随线粒体动力学的紊乱和 uncoupling protein 2 表达的增加。

European Journal of Pharmacology

IF4.7

2025-06-18

PREAI

Ting-Wei Lee; Ting-I Lee; Satoshi Higa; Yu-Hsun Kao; Yi-Jen Chen

Neuregulin 1β enhances pulmonary vein arrhythmogenesis by modulating electrophysiological characteristics, calcium and sodium homeostasis via the AKT/CaMKII pathway Neuregulin 1β通过调节电生理特性、钙和钠稳态，经由AKT/CaMKII通路增强肺静脉的致心律失常作用。

European Journal of Clinical Investigation

IF3.6

2025-06-02

PREAI

Yao-Chang Chen; Wei-Shiang Lin; Shih-Yu Huang; Yen-Yu Lu; Satoshi Higa; Shih-Ann Chen; Yi-Jen Chen

Indoxyl Sulfate Induces Ventricular Arrhythmias Attenuated by Secretoneurin in Right Ventricular Outflow Tract Cardiomyocytes

CARDIOVASCULAR TOXICOLOGY

IF3.7

2025-01-21

OAAI

Hung, Yuan; Cheng, Chen-Chuan; Lu, Yen-Yu; Huang, Shih-Yu; Chen, Yao-Chang; Lin, Fong-Jhih; Lin, Wei-Shiang; Kao, Yu-Hsun; Lin, Yung-Kuo; Chen, Shih-Ann; Chen, Yi-Jen

Spike Protein Impairs Mitochondrial Function in Human Cardiomyocytes: Mechanisms Underlying Cardiac Injury in COVID-19 (vol 12, 877, 2023)

CELLS

IF5.2

2024-11-11

OAAI

Huynh, Tin Van; Rethi, Lekha; Lee, Ting-Wei; Higa, Satoshi; Kao, Yu-Hsun; Chen, Yi-Jen

Spike Protein of SARS-CoV-2 Activates Cardiac Fibrogenesis through NLRP3 Inflammasomes and NF-κB Signaling

CELLS

IF5.2

2024-08-11

OAAI

Tin, Huynh Van; Rethi, Lekha; Higa, Satoshi; Kao, Yu-Hsun; Chen, Yi-Jen

Ibrutinib, a Bruton's tyrosine kinase inhibitor, regulates ventricular electromechanical activities and enhances arrhythmogenesis

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2024-08-01

PREAI

Liu, Chih-Min; Lin, Fong-Jhih; Chhay, Chheng; Chen, Yao-Chang; Lin, Yung-Kuo; Lu, Yen -Yu; Chan, Chao -Shun; Higa, Satoshi; Chen, Shih-Ann; Chen, Yi-Jen

Interleukin-33/ST2 axis involvement in atrial remodeling and arrhythmogenesis

TRANSLATIONAL RESEARCH

IF5.9

2024-06-01

PREAI

Cheng, Tzu-Yu; Chen, Yao-Chang; Li, Shao-Jung; Lin, Fong-Jhih; Lu, Yen-Yu; Lee, Ting-, I; Lee, Ting-Wei; Higa, Satoshi; Kao, Yu-Hsun; Chen, Yi-Jen

Targeting NLRP3 signaling reduces myocarditis-induced arrhythmogenesis and cardiac remodeling

JOURNAL OF BIOMEDICAL SCIENCE

IF12.1

2024-04-22

OAAI

Chin, Chye-Gen; Chen, Yao-Chang; Lin, Fong-Jhih; Lin, Yung-Kuo; Lu, Yen-Yu; Cheng, Tzu-Yu; Chen, Shih-Ann; Chen, Yi-Jen

The Complex Interplay between Imbalanced Mitochondrial Dynamics and Metabolic Disorders in Type 2 Diabetes

CELLS

IF5.2

2023-04-23

OAAI

Huynh, Tin Van; Rethi, Lekha; Rethi, Lekshmi; Chen, Chih-Hwa; Chen, Yi-Jen; Kao, Yu-Hsun

Spike Protein Impairs Mitochondrial Function in Human Cardiomyocytes: Mechanisms Underlying Cardiac Injury in COVID-19

CELLS

IF5.2

2023-03-11

OAAI

Van Huynh, Tin; Rethi, Lekha; Lee, Ting-Wei; Higa, Satoshi; Kao, Yu-Hsun; Chen, Yi-Jen

Editorial: Transcription factors and arrhythmogenesis

FRONTIERS IN PHYSIOLOGY

IF3.4

2023-02-28

OAAI

Kao, Yu-Hsun; Chen, Yi-Jen; Higa, Satoshi; Chattipakorn, Nipon; Santulli, Gaetano

Empagliflozin suppressed cardiac fibrogenesis through sodium-hydrogen exchanger inhibition and modulation of the calcium homeostasis

CARDIOVASCULAR DIABETOLOGY

IF10.6

2023-02-06

OAAI

Chung, Cheng-Chih; Lin, Yung-Kuo; Chen, Yao-Chang; Kao, Yu-Hsun; Yeh, Yung-Hsin; Trang, Nguyen Ngoc; Chen, Yi-Jen

Modulation of post-pacing action potential duration and contractile responses on ventricular arrhythmogenesis in chloroquine-induced long QT syndrome

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2023-02-01

PREAI

Liu, Chih-Min; Lin, Fong-Jhih; Chen, Yao-Chang; Lin, Yung-Kuo; Lu, Yen-Yu; Chan, Chao-Shun; Higa, Satoshi; Chen, Shih-Ann; Chen, Yi-Jen

Gender Difference in Lithium-Induced Sodium Current Dysregulation and Ventricular Arrhythmogenesis in Right Ventricular Outflow Tract Cardiomyocytes

BIOMEDICINES

IF3.9

2022-10-28

OAAI

Liu, Ching-Han; Chen, Yao-Chang; Lu, Yen-Yu; Lin, Yung-Kuo; Higa, Satoshi; Chen, Shih-Ann; Chen, Yi-Jen

Disturbed Cardiac Metabolism Triggers Atrial Arrhythmogenesis in Diabetes Mellitus: Energy Substrate Alternate as a Potential Therapeutic Intervention

CELLS

IF5.2

2022-09-18

OAAI

Lkhagva, Baigalmaa; Lee, Ting-Wei; Lin, Yung-Kuo; Chen, Yao-Chang; Chung, Cheng-Chih; Higa, Satoshi; Chen, Yi-Jen

Effect of macrophage migration inhibitory factor on pulmonary vein arrhythmogenesis through late sodium current

EUROPACE

IF7.4

2022-09-03

OAAI

Chin, Chye-Gen; Chen, Yao-Chang; Lin, Yung-Kuo; Lu, Yen-Yu; Cheng, Wan-Li; Chung, Cheng-Chih; Chen, Shih-Ann; Chen, Yi-Jen

Sex and Age Differences Modulate Association of Vitamin D with Serum Triglyceride Levels

JOURNAL OF PERSONALIZED MEDICINE

IF3

2022-03-11

OAAI

Cheng, Ying-Lien; Lee, Ting-Wei; Lee, Ting-, I; Kao, Yu-Hsun; Wu, Chih-Yin; Chen, Yi-Jen

研究方向