Peter A.C. ’t Hoen - Publications, H-index & Citations

Peter A.C. ’t Hoen

radboud university

73H指数

504论文数

4.7W被引数

收录论文 143

发表时间

Transcription-based identification of uncharacterized genes in the human immune response 基于转录的人类免疫应答中未鉴定基因的识别

European Journal of Human Genetics

IF4.6

2026-05-12

PREAI

Emil E. Vorsteveld; Simone Kersten; Charlotte Kaffa; Annet Simons; Peter A. C. ’t Hoen; Mihai G. Netea; Alexander Hoischen

Integrative transcriptomics and electrophysiological profiling of hiPSC-derived neurons identifies novel druggable pathways in Koolen-de Vries Syndrome 整合转录组学和电生理学分析鉴定出Koolen-de Vries综合征中的新型可靶向药物通路

Molecular Psychiatry

IF10.1

2026-02-12

OAAI

A. H. A. Verboven; S. Puvogel; B. L. Latour; N. Kolsters; E. I. Lewerissa; R. Mijdam; E. Dyke; D. Duineveld; M. Zoodsma; W. J. J. Claassen; A. Oudakker; C. Schoenmaker; D. A. Koolen; B. B. A. de Vries; P. A. C. ’t Hoen; K. Linda; N. Nadif Kasri

287th ENMC International Workshop: Harmonization and federated analysis of myotonic dystrophy registries to model heterogeneous disease trajectories. Hoofddorp, The Netherlands, 28-30 March 2025.第287届ENMC国际研讨会：肌营养不良登记系统的协调与联邦分析，以模拟异质性疾病轨迹。荷兰霍夫多普，2025年3月28日至30日。

Neuromuscular Disorders

IF2.8

2025-10-24

PREAI

Leandre A. la Fontaine; Daniël van As; Guillaume Bassez; Nicholas E. Johnson; Catharina G. Faber; Peter A.C. ’t Hoen

The use of knowledge graphs for drug repurposing: From classical machine learning algorithms to graph neural networks 使用知识图进行药物再利用: 从经典的机器学习算法到图形神经网络

Computers in Biology and Medicine

IF6.3

2025-08-09

OAAI

Siqi Wei; Christo Sasi; Jelle Piepenbrock; Martijn A. Huynen; Peter A.C. ’t Hoen

Ribosome profiling shows variable sensitivity to detect open reading frames for conventional and different types of cryptic T cell antigens 核糖体定位分析显示，在检测常规型和不同类型的隐匿T细胞抗原开放阅读框时，其敏感性存在差异。

MOLECULAR THERAPY METHODS & CLINICAL DEVELOPMENT

IF4.7

2025-03-01

PREAI

Fuchs, Kyra J.; Thomaidou, Sofia; Slik, Arno R. van der; van de Meent, Marian; Hoen, Peter A. C. ' t; Falkenburg, J. H. Frederik; Zaldumbide, Arnaud

SIMPATHIC: Accelerating drug repurposing for rare diseases by exploiting SIMilarities in clinical and molecular PATHology SIMPATHIC: 通过利用临床和分子病理学的相似性来加速罕见疾病的药物再利用

MOLECULAR GENETICS AND METABOLISM

IF3.5

2025-03-01

PREAI

van Karnebeek, Clara D. M.; Muller, Annelieke R.; Benkemoun, Laura; Boussaad, Ibrahim; Cornel, Martina C.; Inthout, Joanna; de Kort, Martin; Martins, Sofia de Oliveira; Prigione, Alessandro; Rigter, Tessel; Roes, Kit C. B.; Sanchez, Anna; Schipper, Raymond; Wilkinson, Mark D.; 't Hoen, Peter A. C.

Multi-omics analysis in inclusion body myositis identifies mir-16 responsible for HLA overexpression

ORPHANET JOURNAL OF RARE DISEASES

IF3.5

2025-01-15

OAAI

Wijnbergen, Daphne; Johari, Mridul; Ozisik, Ozan; 't Hoen, Peter A. C.; Ehrhart, Friederike; Baudot, Anais; Evelo, Chris T.; Udd, Bjarne; Roos, Marco; Mina, Eleni

Integrative analysis of multi-omics data reveals importance of collagen and the PI3K AKT signalling pathway in CAKUT

SCIENTIFIC REPORTS

IF3.9

2024-09-05

OAAI

Bayjanov, Jumamurat R.; Doornbos, Cenna; Ozisik, Ozan; Shin, Woosub; Queralt-Rosinach, Nuria; Wijnbergen, Daphne; Saulnier-Blache, Jean-Sebastien; Schanstra, Joost P.; Buffin-Meyer, Benedicte; Klein, Julie; Fernandez, Jose M.; Kaliyaperumal, Rajaram; Baudot, Anais; 't Hoen, Peter A. C.; Ehrhart, Friederike

Whole-body Ndufs4 knockout mice with isolated complex I deficiency engage a futile adaptive brain response 具有孤立的复合物I缺陷的全身Ndufs4敲除小鼠会产生徒劳的适应性大脑反应

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

IF2.7

2024-09-01

PREAI

van de Wal, Melissa A. E.; Doornbos, Cenna; Bibbe, Janne; Homberg, Judith R.; van Karnebeek, Clara; Huijnen, Martijn; Keijer, Jaap; van Schothorst, Evert M.; T Hoen, Peter A. C. '; Janssen, Mirian C. H.; Adjobo-Hermans, Merel J. W.; Wieckowski, Mariusz R.; Koopman, Werner J. H.

Drug repurposing in Rett and Rett-like syndromes: a promising yet underrated opportunity?

FRONTIERS IN MEDICINE

IF3

2024-07-29

OAAI

Fuchs, Claudia; 't Hoen, Peter A. C.; Mueller, Annelieke R.; Ehrhart, Friederike; Van Karnebeek, Clara D. M.

Network-based integrative multi-omics approach reveals biosignatures specific to COVID-19 disease phases

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2024-07-08

OAAI

Agamah, Francis E.; Ederveen, Thomas H. A.; Skelton, Michelle; Martin, Darren P.; Chimusa, Emile R.; 't Hoen, Peter A. C.

Rare disease research workflow using multilayer networks elucidates the molecular determinants of severity in Congenital Myasthenic Syndromes

NATURE COMMUNICATIONS

IF15.7

2024-02-28

OAAI

Nunez-Carpintero, Iker; Rigau, Maria; Bosio, Mattia; O'Connor, Emily; Spendiff, Sally; Azuma, Yoshiteru; Topf, Ana; Thompson, Rachel; 't Hoen, Peter A. C.; Chamova, Teodora; Tournev, Ivailo; Guergueltcheva, Velina; Laurie, Steven; Beltran, Sergi; Capella-Gutierrez, Salvador; Cirillo, Davide; Lochmueller, Hanns; Valencia, Alfonso

EURO-NMD registry: federated FAIR infrastructure, innovative technologies and concepts of a patient-centred registry for rare neuromuscular disorders Euro-nmd注册表: 联邦公平基础设施，创新技术和以患者为中心的罕见神经肌肉疾病注册表的概念

ORPHANET JOURNAL OF RARE DISEASES

IF3.5

2024-02-14

OAAI

Atalaia, Antonio; Wandrei, Dagmar; Lalout, Nawel; Thompson, Rachel; Tassoni, Adrian; 't Hoen, Peter A. C.; Athanasiou, Dimitrios; Baker, Suzie-Ann; Sakellariou, Paraskevi; Paliouras, Georgios; D'Angelo, Carla; Horvath, Rita; Mancuso, Michelangelo; van der Beek, Nadine; Kornblum, Cornelia; Kirschner, Janbernd; Pareyson, Davide; Bassez, Guillaume; Blacas, Laura; Jacoupy, Maxime; Eng, Catherine; Lamy, Francois; Plancon, Jean-Philippe; Haberlova, Jana; Brusse, Esther; Hoeijmakers, Janneke G. J.; de Visser, Marianne; Claeys, Kristl G.; Paradas, Carmen; Toscano, Antonio; Silani, Vincenzo; Gyenge, Melinda; Reviers, Evy; Hamroun, Dalil; Vroom, Elisabeth; Wilkinson, Mark D.; Lochmuller, Hanns; Evangelista, Teresinha

Drug repurposing for rare: progress and opportunities for the rare disease community

FRONTIERS IN MEDICINE

IF3

2024-01-17

OAAI

Jonker, Anneliene Hechtelt; O'Connor, Daniel; Cavaller-Bellaubi, Maria; Fetro, Christine; Gogou, Maria; Hoen, Peter A. C. T.; de Kort, Martin; Stone, Heather; Valentine, Nivedita; Pasmooij, Anna Maria Gerdina

A multi-omics data analysis workflow packaged as a FAIR Digital Object 包装为公平数字对象的多组学数据分析工作流程

GIGASCIENCE

IF3.9

2024-01-13

OAAI

Niehues, Anna; de Visser, Casper; Hagenbeek, Fiona A.; Kulkarni, Purva; Pool, Rene; Karu, Naama; Kindt, Alida S. D.; Singh, Gurnoor; Vermeiren, Robert R. J. M.; Boomsma, Dorret, I; van Dongen, Jenny; 't Hoen, Peter A. C.; van Gool, Alain J.

PANDORA v2.0: Benchmarking peptide-MHC II models and software improvements

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-12-08

OAAI

Parizi, Farzaneh M.; Marzella, Dario F.; Ramakrishnan, Gayatri; 't Hoen, Peter A. C.; Karimi-Jafari, Mohammad Hossein; Xue, Li C.

SUsPECT: a pipeline for variant effect prediction based on custom long-read transcriptomes for improved clinical variant annotation

BMC GENOMICS

IF3.7

2023-06-06

OAAI

Salz, Renee; Saraiva-Agostinho, Nuno; Vorsteveld, Emil; van der Made, Caspar I.; Kersten, Simone; Stemerdink, Merel; Allen, Jamie; Volders, Pieter-Jan; Hunt, Sarah E.; Hoischen, Alexander; 't Hoen, Peter A. C.

Towards FAIRification of sensitive and fragmented rare disease patient data: challenges and solutions in European reference network registries 走向敏感和零散的罕见疾病患者数据的fairiification: 欧洲参考网络注册中心的挑战和解决方案

ORPHANET JOURNAL OF RARE DISEASES

IF3.5

2022-12-14

OAAI

Vieira, Bruna dos Santos; Bernabe, Cesar H.; Zhang, Shuxin; Abaza, Haitham; Benis, Nirupama; Camara, Alberto; Cornet, Ronald; Le Cornec, Clemence M. A.; 't Hoen, Peter A. C.; Schaefer, Franz; van der Velde, K. Joeri; Swertz, Morris A.; Wilkinson, Mark D.; Jacobsen, Annika; Roos, Marco

Computational approaches for network-based integrative multi-omics analysis 基于网络的综合多组学分析的计算方法

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2022-11-14

OAAI

Agamah, Francis E.; Bayjanov, Jumamurat R.; Niehues, Anna; Njoku, Kelechi F.; Skelton, Michelle; Mazandu, Gaston K.; Ederveen, Thomas H. A.; Mulder, Nicola; Chimusa, Emile R.; 't Hoen, Peter A. C.

Clinical improvement of DM1 patients reflected by reversal of disease-induced gene expression in blood

BMC MEDICINE

IF8.3

2022-11-10

OAAI

van Cruchten, Remco T. P.; van As, Daniel; Glennon, Jeffrey C.; van Engelen, Baziel G. M.; 't Hoen, Peter A. C.

研究方向