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T

Timo Grimmer

TUM University Hospital
H指数:53
被引数:9,784

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Microglial dynamics associate with the spatial pattern of tau deposition in early Alzheimer’s disease

小胶质细胞动力学与早期阿尔茨海默病中tau蛋白沉积的空间模式相关

Alzheimers Research & Therapy
IF7.6
2026-10-120
OA
Marco Öchsner; Matthias Brendel; Nicolai Franzmeier; Lena Trappmann; Mirlind Zaganjori; Ersin Ersoezlue; Carolin Kurz; Jan Haeckert; Julia Utecht; Philine Marie Schirge; Boris Papazov; Oliver Pogarell; Daniel Janowitz; Katharina Buerger; Michael Ewers; Carla Palleis; Endy Weidinger; Gloria Biechele; Sebastian Schuster; Anika Finze; Florian Eckenweber; Rainer Rupprecht; Axel Rominger; Oliver Goldhardt; Timo Grimmer; Daniel Keeser; Sophia Stoecklein; Olaf Dietrich; Peter Bartenstein; Johannes Levin; Günter Höglinger; Robert Perneczky; Boris-Stephan Rauchmann
Herpes simplex virus and kallikrein-related peptidases – a functional connection in Alzheimer‘s disease

单纯疱疹病毒和激肽释放酶相关肽酶——阿尔茨海默病中的功能联系

Alzheimers Research & Therapy
IF7.6
2026-09-240
OAAI
Oliver Goldhardt; Cinthia Mella Robles; Matthias Eberl; Tobias Dreyer; Antoninus Soosaipillai; Eleftherios P. Diamandis; Josef Priller; Dieter Hoffmann; Jochen M. Wettengel; Hianara Aracelly Bustamante; Paula Salazar; Markus Thaler; Carola Otth; Ingrid Pamela Ehrenfeld Slater; Timo Grimmer
APOE-stratified genome-wide association analyses provide insights into the genetic etiology of Alzheimers’s disease

APOE分层的全基因组关联分析为阿尔茨海默病的遗传病因提供了见解

Nature Genetics
IF29
2026-09-140
OAAI
Jesper Qvist Thomassen; Hampton Leonard; Brittany Ulms; Benjamin Grenier-Boley; Sami Heikkinen; Pablo Garcia-González; Atahualapa Castillo-Morales; Masataka Kikuchi; Jungsoo Gim; Han Cao; Fahri Küçükali; Najaf Amin; Dabin Yoon; Itziar de Rojas; Pilar Alvarez Jerez; Victoria Alvarez; Beatrice Arosio; Céline Bellenguez; Sverre Bergh; Kimberley Billingsley; Cornelis Blauwendraat; Merce Boada; Barbara Borroni; Paola Bossù; María J. Bullido; Antonio Daniele; Ángel Carracedo; Alexandre de Mendonça; Mark Cookson; Jürgen Deckert; Martin Dichgans; Srdjan Djurovic; Oriol Dols-Icardo; Carole Dufouil; Emrah Düzel; Valentina Escott-Price; Tormod Fladby; Laura Fratiglioni; Amy K. Y. Fu; Daniela Galimberti; Jose Maria García-Alberca; Vilmantas Giedraitis; Guillermo Garcia-Ribas; Caroline Graff; Timo Grimmer; Edna Grünblatt; Olivier Hanon; Lucrezia Hausner; Stefanie Heilmann-Heimbach; Jakub Hort; Frank Jessen; Kendall Jensen; Caroline Jonson; Yoontae Kim; Nicole Kuznetsov; Ville Leinonen; Anssi Lipponen; Jiao Luo; Mary Makarious; Henna Martiskainen; Carlo Masullo; Patrizia Mecocci; Shima Mehrabian; Pablo Mir; Akinori Miyashita; Susanne Moebus; Kin Y. Mok; Laura Molina Porcel; Fermin Moreno; Benedetta Nacmias; Lucilla Parnetti; Pau Pastor; Jordi Pérez-Tur; Oliver Peters; Yolande A. L. Pijnenburg; Gerard Piñol-Ripoll; Julius Popp; Innocenzo Rainero; Luis M. Real; Steffi Riedel-Heller; Eloy Rodriguez-Rodriguez; Arvid Rongve; Giacomina Rossi; Jose Luis Royo; Dan Rujescu; Ingvild Saltvedt; María Eugenia Sáez; Raquel Sánchez-Valle; Florentino Sanchez-Garcia; Nicolai Sandau; Nikolaos Scarmeas; Katja Scheffler; Norbert Scherbaum; Anja Schneider; Geir Selbæk; Davide Seripa; Vincenzo Solfrizzi; Marco Spallazzi; Alessio Squassina; Eystein Stordal; Niccoló Tesi; Lucio Tremolizzo; Kumar P. Tripathi; Wiesje M. van der Flier; Julie Williams; Jens Wiltfang; Dag Aarsland; Andrew B. Singleton; Philippe Amouyel; Stéphanie Debette; Magda Tsolaki; Gael Nicolas; Sven van der Lee; Henne Holstege; Maria Victoria Fernandez; Patrick Gavin Kehoe; Kristel Sleegers; Martin Ingelsson; Roberta Ghidoni; Ole A. Andreassen; Peter A. Holmans; Pascual Sánchez-Juan; Rebecca Sims; Nancy Y. Ip; Kun Ho Lee; Takeshi Ikeuchi; Alfredo Ramirez; Agustin Ruiz; Mikko Hiltunen; Jean-Charles Lambert; Cornelia van Duijn; Mike Nalls; Ruth Frikke-Schmidt
Neuronal and oligodendroglial, but not astroglial, tau translates to in vivo tau PET signals in individuals with primary tauopathies

神经元和少突胶质细胞的tau，而非星形胶质细胞的tau，与原发性tau蛋白病患者体内的tau PET信号相关。

ACTA NEUROPATHOLOGICA
IF9.3
2024-11-240
OA
Slemann, L; Gnörich, J; Hummel, S; Bartos, LM; Klaus, C; Kling, A; Kusche-Palenga, J; Kunte, ST; Kunze, LH; Englert, AL; Li, YL; Vogler, L; Katzdobler, S; Palleis, C; Bernhardt, A; Jäck, A; Zwergal, A; Hopfner, F; Roemer-Cassiano, SN; Biechele, G; Stöcklein, S; Bischof, G; van Eimeren, T; Drzezga, A; Sabri, O; Barthel, H; Respondek, G; Grimmer, T; Levin, J; Herms, J; Paeger, L; Willroider, M; Beyer, L; Höglinger, GU; Roeber, S; Franzmeier, N; Brendel, M
Associations between sex, body mass index and the individual microglial response in Alzheimer's disease
JOURNAL OF NEUROINFLAMMATION
IF10.1
2024-01-235
OAAI
Biechele, Gloria; Rauchmann, Boris-Stephan; Janowitz, Daniel; Buerger, Katharina; Franzmeier, Nicolai; Weidinger, Endy; Guersel, Selim; Schuster, Sebastian; Finze, Anika; Harris, Stefanie; Lindner, Simon; Albert, Nathalie L.; Wetzel, Christian; Rupprecht, Rainer; Rominger, Axel; Palleis, Carla; Katzdobler, Sabrina; Burow, Lena; Kurz, Carolin; Zaganjori, Mirlind; Trappmann, Lena-Katharina; Goldhardt, Oliver; Grimmer, Timo; Haeckert, Jan; Keeser, Daniel; Stoecklein, Sophia; Morenas-Rodriguez, Estrella; Bartenstein, Peter; Levin, Johannes; Hoeglinger, Guenter U.; Simons, Mikael; Perneczky, Robert; Brendel, Matthias
Two Phase 3 Trials of Gantenerumab in Early Alzheimer's Disease

Gantenerumab在早期阿尔茨海默氏病中的两项3期试验

NEW ENGLAND JOURNAL OF MEDICINE
IF78.5
2023-11-1683
OA
Bateman, Randall J.; Smith, Janice; Donohue, Michael C.; Delmar, Paul; Abbas, Rachid; Salloway, Stephen; Wojtowicz, Jakub; Blennow, Kaj; Bittner, Tobias; Black, Sandra E.; Klein, Gregory; Boada, Merce; Grimmer, Timo; Tamaoka, Akira; Perry, Richard J.; Turner, R. Scott; Watson, David; Woodward, Michael; Thanasopoulou, Angeliki; Lane, Christopher; Baudler, Monika; Fox, Nick C.; Cummings, Jeffrey L.; Fontoura, Paulo; Doody, Rachelle S.
Automated antigen assays display a high heterogeneity for the detection of SARS-CoV-2 variants of concern, including several Omicron sublineages
MEDICAL MICROBIOLOGY AND IMMUNOLOGY
IF3
2023-08-101
OAAI
Osterman, Andreas; Krenn, Franziska; Iglhaut, Maximilian; Badell, Irina; Lehner, Andreas; Spaeth, Patricia M. M.; Stern, Marcel; Both, Hanna; Bender, Sabine; Muenchhoff, Maximilian; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Grimmer, Timo; Durner, Juergen; Czibere, Ludwig; Daechert, Christopher; Grzimek-Koschewa, Natascha; Protzer, Ulrike; Kaderali, Lars; Baldauf, Hanna-Mari; Keppler, Oliver T. T.
Individual regional associations between Aβ-, tau- and neurodegeneration (ATN) with microglial activation in patients with primary and secondary tauopathies
MOLECULAR PSYCHIATRY
IF10.1
2023-07-2613
OAAI
Finze, Anika; Biechele, Gloria; Rauchmann, Boris-Stephan; Franzmeier, Nicolai; Palleis, Carla; Katzdobler, Sabrina; Weidinger, Endy; Guersel, Selim; Schuster, Sebastian; Harris, Stefanie; Schmitt, Julia; Beyer, Leonie; Gnoerich, Johannes; Lindner, Simon; Albert, Nathalie L.; Wetzel, Christian H.; Rupprecht, Rainer; Rominger, Axel; Danek, Adrian; Burow, Lena; Kurz, Carolin; Tato, Maia; Utecht, Julia; Papazov, Boris; Zaganjori, Mirlind; Trappmann, Lena-Katharina; Goldhardt, Oliver; Grimmer, Timo; Haeckert, Jan; Janowitz, Daniel; Buerger, Katharina; Keeser, Daniel; Stoecklein, Sophia; Dietrich, Olaf; Morenas-Rodriguez, Estrella; Barthel, Henryk; Sabri, Osama; Bartenstein, Peter; Simons, Mikael; Haass, Christian; Hoeglinger, Gunter U.; Levin, Johannes; Perneczky, Robert; Brendel, Matthias
Elecsys Cerebrospinal Fluid Immunoassays Accurately Detect Alzheimer's Disease Regardless of Concomitant Small Vessel Disease

Elecsys脑脊液免疫测定法可准确检测阿尔茨海默氏病，而与伴随的小血管疾病无关

JOURNAL OF ALZHEIMERS DISEASE
IF3.1
2023-05-163
OAAI
Ortner, Marion; Lanz, Korbinian; Goldhardt, Oliver; Mueller-Sarnowski, Felix; Diehl-Schmid, Janine; Foerstl, Hans; Hedderich, Dennis M.; Yakushev, Igor; Logan, Chad A.; Weinberger, Jan-Philipp; Simon, Maryline; Grimmer, Timo
GRADUATE I AND II: Findings of Two Phase III Randomized Placebo-controlled Studies Assessing the Efficacy and Safety of Subcutaneous Gantenerumab in Early Alzheimer's Disease (AD)
NEUROLOGY
IF8.5
2023-04-253
PRE
Smith, Janice; Donohue, Michael C.; Gruendl, Elisabeth; Grimmer, Timo; Perry, Richard J.; Black, Sandra E.; Salloway, Stephen; Lyons, Marco; Rutten-Jacobs, Loes; Bittner, Tobias; Blennow, Kaj; Pelentrides, Chris; Barkhof, Frederik; Tonietto, Matteo; Baudler-Klein, Monika; Fontoura, Paulo; Doody, Rachelle S.

研究方向

暂未获取到该数据
A
Alexander Drzezga
H 指数:86论文数:762被引数:2.9万
J
Janine Diehl‐Schmid
H 指数:55论文数:314被引数:1.8万
H
Hans Förstl
H 指数:71论文数:668被引数:2.0万
C
Christian Sorg
H 指数:56论文数:435被引数:1.4万
R
Robert Perneczky
H 指数:71论文数:596被引数:2.0万
Y
Yakushev, Igor
H 指数:0论文数:4被引数:97
A
Alexander Kurz
H 指数:65论文数:360被引数:2.0万
P
Panagiotis Alexopoulos
H 指数:40论文数:215被引数:5,328
M
Marion Ortner
H 指数:18论文数:83被引数:1,066
S
Stefan Förster
H 指数:43论文数:210被引数:9,014