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M

Murat Iskar

guardant health, inc
H指数:45
被引数:1.8万

个人简介

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教育背景

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工作经历

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荣誉奖项

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Pipeline Olympics: continuable benchmarking of computational workflows for DNA methylation sequencing data against an experimental gold standard

Pipeline Olympics：针对DNA甲基化测序数据，基于实验金标准的可延续性计算工作流基准测试

NUCLEIC ACIDS RESEARCH
IF13.1
2025-10-280
OAAI
Lin, Yu-Yu; Breuer, Kersten; Weichenhan, Dieter; Lafrenz, Pascal; Sarnataro, Antonella; Wilk, Agata; Chepeleva, Maryna; Mucke, Oliver; Schonung, Maximilian; Petermann, Franziska; Kensche, Philip Reiner; Weiser, Lena; Thommen, Frank; Giacomelli, Gideon; Nordstroem, Karl; Gonzalez-Avalos, Edahi; Merkel, Angelika; Kretzmer, Helene; Fischer, Jonas; Kramer, Stephen; Iskar, Murat; Wolf, Stephan; Buchhalter, Ivo; Esteller, Manel; Lawerenz, Christian; Twardziok, Sven; Zapatka, Marc; Hovestadt, Volker; Schlesner, Matthias; Schulz, Marcel H.; Hoffmann, Steve; Gerhauser, Clarissa; Walter, Jorn; Hartmann, Mark; Lipka, Daniel B.; Assenov, Yassen; Bock, Christoph; Plass, Christoph; Toth, Reka; Lutsik, Pavlo
Integrative multi-omics reveals a regulatory and exhausted T-cell landscape in CLL and identifies galectin-9 as an immunotherapy target

整合多组学揭示CLL中调节性及耗竭性T细胞景观，并鉴定出galectin-9作为免疫治疗靶点

Nature Communications
IF15.7
2025-08-070
OA
L. Llaó-Cid; JKL Wong; I. Fernandez Botana; Y. Paul; M. Wierz; L-M Pilger; A. Floerchinger; CL Tan; S. Gonder; G. Pagano; M. Chazotte; K. Bestak; C. Schifflers; M. Iskar; T. Roider; F. Czernilofsky; P-M Bruch; JP Mallm; A. Cosma; DE Campton; E. Gerhard-Hartmann; A. Rosenwald; D. Colomer; E. Campo; D. Schapiro; EW Green; S. Dietrich; P. Lichter; E. Moussay; J. Paggetti; M. Zapatka; M. Seiffert
Integration of transcriptomics, proteomics and loss-of-function screening reveals WEE1 as a target for combination with dasatinib against proneural glioblastoma
CANCER LETTERS
IF10.1
2024-11-010
OA
Alhalabi, Obada T.; Goettmann, Mona; Gold, Maxwell P.; Schlue, Silja; Hielscher, Thomas; Iskar, Murat; Kessler, Tobias; Hai, Ling; Lokumcu, Tolga; Cousins, Clara C.; Herold-Mende, Christel; Hessling, Bernd; Horschitz, Sandra; Jabali, Ammar; Koch, Philipp; Baumgartner, Ulrich; Day, Bryan W.; Wick, Wolfgang; Sahm, Felix; Krieg, Sandro M.; Fraenkel, Ernest; Phillips, Emma; Goidts, Violaine
Proteomic, Metabolomic, and Fatty Acid Profiling of Small Extracellular Vesicles from Glioblastoma Stem-Like Cells and Their Role in Tumor Heterogeneity

胶质母细胞瘤干样细胞小胞外囊泡的蛋白质组学、代谢组学和脂肪酸谱及其在肿瘤异质性中的作用

ACS NANO
IF16
2024-01-1110
OAAI
Lokumcu, Tolga; Iskar, Murat; Schneider, Martin; Helm, Dominic; Klinke, Glynis; Schlicker, Lisa; Bethke, Frederic; Mu''ller, Gabriele; Richter, Karsten; Poschet, Gernot; Phillips, Emma; Goidts, Violaine
Proteogenomics refines the molecular classification of chronic lymphocytic leukemia
NATURE COMMUNICATIONS
IF15.7
2022-10-2020
OAAI
Herbst, Sophie A.; Vesterlund, Mattias; Helmboldt, Alexander J.; Jafari, Rozbeh; Siavelis, Ioannis; Stahl, Matthias; Schitter, Eva C.; Liebers, Nora; Brinkmann, Berit J.; Czernilofsky, Felix; Roider, Tobias; Bruch, Peter-Martin; Iskar, Murat; Kittai, Adam; Huang, Ying; Lu, Junyan; Richter, Sarah; Mermelekas, Georgios; Umer, Husen Muhammad; Knoll, Mareike; Kolb, Carolin; Lenze, Angela; Cao, Xiaofang; Osterholm, Cecilia; Wahnschaffe, Linus; Herling, Carmen; Scheinost, Sebastian; Ganzinger, Matthias; Mansouri, Larry; Kriegsmann, Katharina; Kriegsmann, Mark; Anders, Simon; Zapatka, Marc; Del Poeta, Giovanni; Zucchetto, Antonella; Bomben, Riccardo; Gattei, Valter; Dreger, Peter; Woyach, Jennifer; Herling, Marco; Muller-Tidow, Carsten; Rosenquist, Richard; Stilgenbauer, Stephan; Zenz, Thorsten; Huber, Wolfgang; Tausch, Eugen; Lehtioe, Janne; Dietrich, Sascha
A synergistic interaction between HDAC- and PARP inhibitors in childhood tumors with chromothripsis
INTERNATIONAL JOURNAL OF CANCER
IF4.7
2022-04-286
OA
Khalid, Umar; Simovic, Milena; Hammann, Linda A.; Iskar, Murat; Wong, John K. L.; Kumar, Rithu; Jugold, Manfred; Sill, Martin; Bolkestein, Michiel; Kolb, Thorsten; Hergt, Michaela; Devens, Frauke; Ecker, Jonas; Kool, Marcel; Milde, Till; Westermann, Frank; Benner, Axel; Lewis, Joe; Dietrich, Sascha; Pfister, Stefan M.; Lichter, Peter; Zapatka, Marc; Ernst, Aurelie
Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity
IMMUNITY
IF26.3
2021-12-0172
OAAI
Hanna, Bola S.; Llao-Cid, Laura; Iskar, Murat; Roessner, Philipp M.; Klett, Lara C.; Wong, John K. L.; Paul, Yashna; Ioannou, Nikolaos; Ozturk, Selcen; Mack, Norman; Kalter, Verena; Colomer, Dolors; Campo, Elias; Bloehdorn, Johannes; Stilgenbauer, Stephan; Dietrich, Sascha; Schmidt, Manfred; Gabriel, Richard; Rippe, Karsten; Feuerer, Markus; Ramsay, Alan G.; Lichter, Peter; Zapatka, Marc; Seiffert, Martina
Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations

原发性松果体实质肿瘤的分子亚组揭示了与临床参数和遗传改变相关的不同亚型

ACTA NEUROPATHOLOGICA
IF9.3
2019-11-2549
OAAI
Pfaff, Elke; Aichmueller, Christian; Sill, Martin; Stichel, Damian; Snuderl, Matija; Karajannis, Matthias A.; Schuhmann, Martin U.; Schittenhelm, Jens; Hasselblatt, Martin; Thomas, Christian; Korshunov, Andrey; Rhizova, Marina; Wittmann, Andrea; Kaufhold, Anna; Iskar, Murat; Ketteler, Petra; Lohmann, Dietmar; Orr, Brent A.; Ellison, David W.; von Hoff, Katja; Mynarek, Martin; Rutkowski, Stefan; Sahm, Felix; von Deimling, Andreas; Lichter, Peter; Kool, Marcel; Zapatka, Marc; Pfister, Stefan M.; Jones, David T. W.
Identification and Analyses of Extra-Cranial and Cranial Rhabdoid Tumor Molecular Subgroups Reveal Tumors with Cytotoxic T Cell Infiltration
CELL REPORTS
IF6.9
2019-11-0176
OAAI
Chun, Hye-Jung E.; Johann, Pascal D.; Milne, Katy; Zapatka, Marc; Buellesbach, Annette; Ishaque, Naveed; Iskar, Murat; Erkek, Serap; Wei, Lisa; Tessier-Cloutier, Basile; Lever, Jake; Titmuss, Emma; Topham, James T.; Bowlby, Reanne; Chuah, Eric; Mungall, Karen L.; Ma, Yussanne; Mungall, Andrew J.; Moore, Richard A.; Taylor, Michael D.; Gerhard, Daniela S.; Jones, Steven J. M.; Korshunov, Andrey; Gessler, Manfred; Kerl, Kornelius; Hasselblatt, Martin; Fruehwald, Michael C.; Perlman, Elizabeth J.; Nelson, Brad H.; Pfister, Stefan M.; Marra, Marco A.; Kool, Marcel
Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks
MOLECULAR SYSTEMS BIOLOGY
IF7.7
2019-05-2234
OAAI
Mallm, Jan-Philipp; Iskar, Murat; Ishaque, Naveed; Klett, Lara C.; Kugler, Sabrina J.; Muino, Jose M.; Teif, Vladimir B.; Poos, Alexandra M.; Grossmann, Sebastian; Erdel, Fabian; Tavernari, Daniele; Koser, Sandra D.; Schumacher, Sabrina; Brors, Benedikt; Koenig, Rainer; Remondini, Daniel; Vingron, Martin; Stilgenbauer, Stephan; Lichter, Peter; Zapatka, Marc; Mertens, Daniel; Rippe, Karsten
Tumor-derived exosomes modulate PD-L1 expression in monocytes

肿瘤来源的外泌体调节单核细胞中的PD-L1表达

SCIENCE IMMUNOLOGY
IF16.3
2017-07-21266
OAAI
Haderk, Franziska; Schulz, Ralph; Iskar, Murat; Cid, Laura Llao; Worst, Thomas; Willmund, Karolin V.; Schulz, Angela; Warnken, Uwe; Seiler, Jana; Benner, Axel; Nessling, Michelle; Zenz, Thorsten; Gobel, Maria; Durig, Jan; Diederichs, Sven; Paggetti, Jerome; Moussay, Etienne; Stilgenbauer, Stephan; Zapatka, Marc; Lichter, Peter; Seiffert, Martina

研究方向

暂未获取到该数据
M
Marc Zapatka
H 指数:63论文数:306被引数:3.5万
P
Peter Lichter
H 指数:146论文数:1,017被引数:9.8万
P
Peer Bork
H 指数:233论文数:961被引数:37.8万
S
Stefan M. Pfister
H 指数:159论文数:2,105被引数:12.7万
M
Martin Beck
H 指数:72论文数:262被引数:1.8万
A
Alessandro Ori‬‬
H 指数:46论文数:199被引数:8,027
M
Marcel Kool
H 指数:119论文数:957被引数:8.4万
D
Dirk Schübeler
H 指数:83论文数:168被引数:2.9万
S
Stephan Stilgenbauer
H 指数:126论文数:1,220被引数:7.3万
S
Sascha Dietrich
H 指数:48论文数:375被引数:1.0万