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Serum protein profiles differ with adalimumab and ustekinumab treatment in moderately to severely active Crohn's disease 血清蛋白谱在阿达木单抗和乌司奴单抗治疗中度至重度活动性克罗恩病中存在差异 Venkat, Swati; Zeeman, Martha; Hart, Amy; Bhagat, Sunita; Galbraith, David A.; Hoops, Timothy; Ufberg, Paul J.; Izanec, James; Freeman, Tom C.; Mcrae, Bradford; Shinzaki, Shinichiro; Jairath, Vipul; Panaccione, Remo; Sands, Bruce E.; Branigan, Patrick 分享 收藏
Guselkumab binding to CD64+ IL-23-producing myeloid cells enhances potency for neutralizing IL-23 signaling Guselkumab结合CD64+ IL-23产生髓系细胞，增强了中和IL-23信号的能力 Sachen, Kacey L.; Hammaker, Deepa; Sarabia, Indra; Stoveken, Brian; Hartman, John; Leppard, Kristin L.; Manieri, Nicholas A.; Bao, Phuc; Greving, Carrie; Lacy, Eilyn R.; Duprie, Matthew; Wertheimer, Joshua; Deming, Janise D.; Brown, Joseph; Hart, Amy; Li, He (Hurley); Freeman, Tom C.; Keyes, Brice; Kohler, Kristen; White, Ian; Karpowich, Nathan; Steele, Ruth; Elloso, M. Merle; Fakharzadeh, Steven; Goyal, Kavitha; Lavie, Frederic; Abreu, Maria T.; Allez, Matthieu; Atreya, Raja; Bissonnette, Robert; Eyerich, Kilian; Krueger, James G.; Mcgonagle, Dennis; Mcinnes, Iain B.; Ritchlin, Christopher; Fourie, Anne M. 分享 收藏
DOP069 Guselkumab maintenance therapy mediates further improvements in intestinal immune homeostasis and mucosal healing in patients with ulcerative colitis Hart, A.; Sridhar, S.; Venkat, S.; Huang, K. H. G.; Yarandi, S.; Germinaro, M.; Vetter, M. L.; Rubin, D. T.; Dignass, A.; Cua, D.; Freeman, T.; Waterworth, D.; Mcrae, B.; Verstockt, B.; Branigan, P. 分享 收藏
Guselkumab induction therapy results in molecular resolution of inflammation in moderately to severely active Ulcerative Colitis: results from the Phase 3 QUASAR induction study Sridhar, S.; Hart, A.; Venkat, S.; Huang, K. H. G.; Yarandi, S.; Germinaro, M.; Vetter, M.; Rubin, D. T.; Dignass, A.; Cua, D.; Freeman, T.; Waterworth, D.; Mcrae, B.; Verstockt, B.; Branigan, P. 分享 收藏
Guselkumab Decreases Key Cellular Inflammatory Processes Across Ileum and Colon Tissue in Crohn's Disease Richards, Dylan; Venkat, Swati; Ruane, Darren; Zeeman, Martha; Terry, Natalie A.; Vetter, Marion; Gomez, Mario; Cua, Daniel; Freeman, Tom C.; Mcrae, Bradford; Feagan, Brian G.; Reinisch, Walter; Branigan, Patrick 分享 收藏
Guselkumab Binding to CD64+IL-23-Producing Myeloid Cells Enhances Potency for Neutralizing IL-23 Signaling Allegretti, Jessica R.; Atreya, Raja; Abreu, Maria T.; Hart, Amy; Li, He (Hurley); Freeman, Tom C.; Lacy, Eilyn; Duprie, Matthew; Bao, Phuc; Smets, Tina; Wertheimer, Joshua; Sarabia, Indra; Kohler, Kristen; Fourie, Anne; Sachen, Kacey 分享 收藏
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GUSELKUMAB INDUCTION RESTORES INTESTINAL IMMUNE HOMEOSTASIS AND PROMOTES EPITHELIAL REPAIR IN MODERATELY TO SEVERELY ACTIVE ULCERATIVE COLITIS GUSELKUMAB诱导恢复中度至重度活动性溃疡性结肠炎的肠道免疫稳态并促进上皮修复 Sridhar, S.; Hart, A.; Venkat, S.; Ruane, D.; Horowitz, D.; Lee, T.; Waterworth, D.; Huang, K. H. G.; Germinaro, M.; Vetter, M.; Cua, D.; Freeman, T. C.; Sisk, C.; Mcrae, B.; Verstockt, B.; Rubin, D. T.; Sands, B. E.; Branigan, P. 分享 收藏
GUSELKUMAB AND GOLIMUMAB COMBINATION INDUCTION THERAPY IN ULCERATIVE COLITIS RESULTS IN EARLY LOCAL TISSUE HEALING THAT IS SUSTAINED THROUGH GUSELKUMAB MAINTENANCE THERAPY Guselkumab和Golimumab联合诱导治疗在溃疡性结肠炎中可导致早期局部组织愈合，并通过Guselkumab维持治疗得到持续。 Richards, D.; Vetter, M.; Germinaro, M.; Verstockt, B.; Atreya, R.; Panes, J.; Sands, B. E.; Feagan, B.; Mcrae, B.; Cua, D.; Branigan, P.; Freeman, T. C. 分享 收藏
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Multiclonal human origin and global expansion of an endemic bacterial pathogen of livestock Yebra, Gonzalo; Harling-Lee, Joshua D.; Lycett, Samantha; Aarestrup, Frank M.; Larsen, Gunhild; Cavaco, Lina M.; Seo, Keun Seok; Abraham, Sam; Norris, Jacqueline M.; Schmidt, Tracy; Ehlers, Marthie M.; Sordelli, Daniel O.; Buzzola, Fernanda R.; Gebreyes, Wondwossen A.; Goncalves, Juliano L.; Dos Santos, Marcos, V; Zakaria, Zunita; Rall, Vera L. M.; Keane, Orla M.; Niedziela, Dagmara A.; Paterson, Gavin K.; Holmes, Mark A.; Freeman, Tom C.; Fitzgerald, J. Ross 分享 收藏
COVID19 Disease Map, a computational knowledge repository of virus-host interaction mechanisms COVID19疾病图谱，病毒-宿主相互作用机制的计算知识库 Ostaszewski, Marek; Niarakis, Anna; Mazein, Alexander; Kuperstein, Inna; Phair, Robert; Orta-Resendiz, Aurelio; Singh, Vidisha; Aghamiri, Sara Sadat; Acencio, Marcio Luis; Glaab, Enrico; Ruepp, Andreas; Fobo, Gisela; Montrone, Corinna; Brauner, Barbara; Frishman, Goar; Gomez, Luis Cristobal Monraz; Somers, Julia; Hoch, Matti; Gupta, Shailendra Kumar; Scheel, Julia; Borlinghaus, Hanna; Czauderna, Tobias; Schreiber, Falk; Montagud, Arnau; de Leon, Miguel Ponce; Funahashi, Akira; Hiki, Yusuke; Hiroi, Noriko; Yamada, Takahiro G.; Draeger, Andreas; Renz, Alina; Naveez, Muhammad; Bocskei, Zsolt; Messina, Francesco; Boernigen, Daniela; Fergusson, Liam; Conti, Marta; Rameil, Marius; Nakonecnij, Vanessa; Vanhoefer, Jakob; Schmiester, Leonard; Wang, Muying; Ackerman, Emily E.; Shoemaker, Jason E.; Zucker, Jeremy; Oxford, Kristie; Teuton, Jeremy; Kocakaya, Ebru; Summak, Gokce Yagmur; Hanspers, Kristina; Kutmon, Martina; Coort, Susan; Eijssen, Lars; Ehrhart, Friederike; Rex, Devasahayam Arokia Balaya; Slenter, Denise; Martens, Marvin; Nhung Pham; Haw, Robin; Jassal, Bijay; Matthews, Lisa; Orlic-Milacic, Marija; Ribeiro, Andrea Senff; Rothfels, Karen; Shamovsky, Veronica; Stephan, Ralf; Sevilla, Cristoffer; Varusai, Thawfeek; Ravel, Jean-Marie; Fraser, Rupsha; Ortseifen, Vera; Marchesi, Silvia; Gawron, Piotr; Smula, Ewa; Heirendt, Laurent; Satagopam, Venkata; Wu, Guanming; Riutta, Anders; Golebiewski, Martin; Owen, Stuart; Goble, Carole; Hu, Xiaoming; Overall, Rupert W.; Maier, Dieter; Bauch, Angela; Gyori, Benjamin M.; Bachman, John A.; Vega, Carlos; Groues, Valentin; Vazquez, Miguel; Porras, Pablo; Licata, Luana; Iannuccelli, Marta; Sacco, Francesca; Nesterova, Anastasia; Yuryev, Anton; de Waard, Anita; Turei, Denes; Luna, Augustin; Babur, Ozgun; Soliman, Sylvain; Valdeolivas, Alberto; Esteban-Medina, Marina; Pena-Chilet, Maria; Rian, Kinza; Helikar, Tomas; Puniya, Bhanwar Lal; Modos, Dezso; Treveil, Agatha; Olbei, Marton; De Meulder, Bertrand; Ballereau, Stephane; Dugourd, Aurelien; Naldi, Aurelien; Noel, Vincent; Calzone, Laurence; Sander, Chris; Demir, Emek; Korcsmaros, Tamas; Freeman, Tom C.; Auge, Franck; Beckmann, Jacques S.; Hasenauer, Jan; Wolkenhauer, Olaf; Wilighagen, Egon L.; Pico, Alexander R.; Evelo, Chris T.; Gillespie, Marc E.; Stein, Lincoln D.; Hermjakob, Henning; D'Eustachio, Peter; Saez-Rodriguez, Julio; Dopazo, Joaquin; Valencia, Alfonso; Kitano, Hiroaki; Barillot, Emmanuel; Auffray, Charles; Balling, Rudi; Schneider, Reinhard 分享 收藏
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Recruitment of inflammatory monocytes by senescent fibroblasts inhibits antigen-specific tissue immunity during human aging Chambers, Emma S.; Vukmanovic-Stejic, Milica; Shih, Barbara B.; Trahair, Hugh; Subramanian, Priya; Devine, Oliver P.; Glanville, James; Gilroy, Derek; Rustin, Malcolm H. A.; Freeman, Tom C.; Mabbott, Neil A.; Akbar, Arne N. 分享 收藏
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Vitamin D3 replacement enhances antigen-specific immunity in older adults Chambers, Emma S.; Vukmanovic-Stejic, Milica; Turner, Carolin T.; Shih, Barbara B.; Trahair, Hugh; Pollara, Gabriele; Tsaliki, Evdokia; Rustin, Malcolm; Freeman, Tom C.; Mabbott, Neil A.; Noursadeghi, Mahdad; Martineau, Adrian R.; Akbar, Arne N. 分享 收藏
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Setting the basis of best practices and standards for curation and annotation of logical models in biology-highlights of the [BC]2 2019 CoLoMoTo/SysMod Workshop Niarakis, Anna; Kuiper, Martin; Ostaszewski, Marek; Sheriff, Rahuman S. Malik; Casals-Casas, Cristina; Thieffry, Denis; Freeman, Tom C.; Thomas, Paul; Toure, Vasundra; Noel, Vincent; Stoll, Gautier; Saez-Rodriguez, Julio; Naldi, Aurelien; Oshurko, Eugenia; Xenarios, Ioannis; Soliman, Sylvain; Chaouiya, Claudine; Helikar, Tomas; Calzone, Laurence 分享 收藏
Identification of Complex Rumen Microbiome Interaction Within Diverse Functional Niches as Mechanisms Affecting the Variation of Methane Emissions in Bovine Martinez-Alvaro, Marina; Auffret, Marc D.; Stewart, Robert D.; Dewhurst, Richard J.; Duthie, Carol-Anne; Rooke, John A.; Wallace, R. John; Shih, Barbara; Freeman, Tom C.; Watson, Mick; Roehe, Rainer 分享 收藏
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