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Toshio Kitamura

foundation for biomedical research innovation at kobe

86H指数
563论文数
3.7W被引数
收录论文 177
发表时间
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MECOM promotes leukemia progression and inhibits mast cell differentiation through functional competition with GATA2MECOM通过功能竞争GATA2促进白血病进展并抑制肥大细胞分化
errLeukemia
IF13.4
err2026-05-05
err0
errOAAI
errKohei Iida; Mayuko Nakanishi; Jakushin Nakahara; Shuhei Asada; Tomoya Isobe; Tomohiro Yabushita; Tsuyoshi Fukushima; Yosuke Tanaka; Manabu Ozawa; Yasuhiro Yamada; Toshio Kitamura; Keita Yamamoto; Susumu Goyama
err分享
err收藏
Recruitment of BRD4 to the ASXL1 genomic targets depends on the extra-terminal domain of BRD4BRD4募集到ASXL1基因组靶点依赖于BRD4的末端结构域
errNature Communications
IF15.7
err2026-02-17
err0
errOAAI
errKarthik Selvam; Shuang Lu; Clémence Messmer; Yakun Pang; Soumi Biswas; Moustafa Khalil; Peng Zhang; Rima Tulaiha; Ming-Ming Zhou; Toshio Kitamura; Shannon M. Lauberth; M. Andres Blanco; Feng-Chun Yang; El Bachir Affar; Zibo Zhao; Lei Zeng; Lu Wang; Tatiana G. Kutateladze
err分享
err收藏
Prospective isolation of mouse and human hematopoietic stem cells using PLXDC2使用PLXDC2对小鼠和人造血干细胞进行前瞻性分离
errCommunications Biology
IF5.1
err2025-12-10
err0
errOAAI
errYosuke Tanaka; Yasushi Kubota; Riko Kikuchi; Tomohiro Yabushita; Takaharu Kimura; Ivo Lieberam; Jillian L. Barlow; Josh W. Bramley; Tsuyoshi Fukushima; Chiaki Sakuma; Takashi Shibata; Masataka Nakagawa; Yasunori Kurosawa; Toshiaki Maruyama; C. J. Okumura; Yuichiro Arima; Yoshinori Sato; Yasuo Ono; Teruo Akuta; Hidenobu Mizuno; David G. Kent; Thomas M. Jessell; Susumu Goyama; Hidekazu Nishikii; Shinya Kimura; Satoshi Yamazaki; Toshio Suda; Toshio Kitamura
err分享
err收藏
Breakdown of blood–brain barrier, astrocytic endfeet swelling, and abnormal behaviors by blockade of TROY signaling in TROY-Fc transgenic mice血脑屏障破坏、星形胶质细胞终足肿胀及异常行为：TROY-Fc转基因小鼠中TROY信号阻滞的效应
errbrain behavior and immunity
IF0
err2025-08-18
err0
PREAI
errTadasuke Komori; Tomoko Hisaoka; Emi Kuriyama; Mizuki Kajimoto; Naoyuki Nakao; Toshio Kitamura; Yoshihiro Morikawa
err分享
err收藏
Machine Learning-Based Predictive Modeling Maximizes the Efficacy of mTOR/p53 Co-Targeting Therapy Against AML基于机器学习的预测模型最大化mTOR/p53协同靶向疗法对AML的疗效
errCancer Science
IF4.3
err2025-08-11
err0
errOAAI
errJingmei Li; Emi Sugimoto; Keita Yamamoto; Yutong Dai; Wenyu Zhang; Yu-Hsuan Chang; Jakushin Nakahara; Tomohiro Yabushita; Toshio Kitamura; Sung-Joon Park; Kenta Nakai; Susumu Goyama
err分享
err收藏
Clonal hematopoiesis-related mutant ASXL1 promotes atherosclerosis in mice via dysregulated innate immunity
errcardiovascular research
IF10.8
err2024-12-09
err0
PREAI
errSato, Naru; Goyama, Susumu; Chang, Yu-Hsuan; Miyawaki, Masashi; Fujino, Takeshi; Koide, Shuhei; Denda, Tamami; Liu, Xiaoxiao; Ueda, Koji; Yamamoto, Keita; Asada, Shuhei; Takeda, Reina; Yonezawa, Taishi; Tanaka, Yosuke; Honda, Hiroaki; Ota, Yasunori; Shibata, Takuma; Sekiya, Motohiro; Isobe, Tomoya; Lamagna, Chrystelle; Masuda, Esteban; Iwama, Atsushi; Shimano, Hitoshi; Inoue, Jun-ichiro; Miyake, Kensuke; Kitamura, Toshio
err分享
err收藏
Structural basis for the effects of Ser387 phosphorylation of MgcRacGAP on its GTPase-activating activities for CDC42 and RHOA
errJOURNAL OF STRUCTURAL BIOLOGY
IF5.1
err2024-12-01
err0
PREAI
errMurayama, Kazutaka; Kato-Murayama, Miyuki; Hosaka, Toshiaki; Kitamura, Toshio; Yokoyama, Shigeyuki; Shirouzu, Mikako
err分享
err收藏
PCYT1A Is a Metabolic Vulnerability in Monocytic Acute Myeloid LeukemiaPCYT1A 是单核细胞急性髓系白血病中的代谢脆弱性。
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errNakahara, Jakushin; Yamamoto, Keita; Yabushita, Tomohiro; Chinen, Takumi; Ito, Kei; Takeda, Yutaka; Kitagawa, Daiju; Kitamura, Toshio; Goyama, Susumu
err分享
err收藏
Prostaglandin E2-EP2/EP4 signaling induces immunosuppression in human cancer by impairing bioenergetics and ribosome biogenesis in immune cells前列腺素E2-EP2/EP4信号通过损害免疫细胞中的生物能学和核糖体生物合成来诱导人类癌症的免疫抑制
errNATURE COMMUNICATIONS
IF15.7
err2024-11-01
err0
errOAAI
errPunyawatthananukool, Siwakorn; Matsuura, Ryuma; Wongchang, Thamrong; Katsurada, Nao; Tsuruyama, Tatsuaki; Tajima, Masaki; Enomoto, Yutaka; Kitamura, Toshio; Kawashima, Masahiro; Toi, Masakazu; Yamanoi, Koji; Hamanishi, Junzo; Hisamori, Shigeo; Obama, Kazutaka; Charoensawan, Varodom; Thumkeo, Dean; Narumiya, Shuh
err分享
err收藏
NPM1-fusion proteins promote myeloid leukemogenesis through XPO1-dependent HOX activation
errLEUKEMIA
IF13.4
err2024-10-23
err0
errOAAI
errShimosato, Yuko; Yamamoto, Keita; Jia, Yuhan; Zhang, Wenyu; Shiba, Norio; Hayashi, Yasuhide; Ito, Shuichi; Kitamura, Toshio; Goyama, Susumu
err分享
err收藏
HDAC7 is a potential therapeutic target in acute erythroid leukemia
errLEUKEMIA
IF13.4
err2024-09-15
err0
errOAAI
errZhang, Wenyu; Yamamoto, Keita; Chang, Yu-Hsuan; Yabushita, Tomohiro; Hao, Yangying; Shimura, Ruka; Nakahara, Jakushin; Shikata, Shiori; Iida, Kohei; Chen, Qianyi; Zhang, Xichen; Kitamura, Toshio; Goyama, Susumu
err分享
err收藏
Hyperactive Natural Killer cells in Rag2 knockout mice inhibit the development of acute myeloid leukemia
errCOMMUNICATIONS BIOLOGY
IF5.1
err2023-12-21
err6
errOAAI
errSugimoto, Emi; Li, Jingmei; Hayashi, Yasutaka; Iida, Kohei; Asada, Shuhei; Fukushima, Tsuyoshi; Tamura, Moe; Shikata, Shiori; Zhang, Wenyu; Yamamoto, Keita; Kawabata, Kimihito Cojin; Kawase, Tatsuya; Saito, Takeshi; Yoshida, Taku; Yamazaki, Satoshi; Kaito, Yuta; Imai, Yoichi; Denda, Tamami; Ota, Yasunori; Fukuyama, Tomofusa; Tanaka, Yosuke; Enomoto, Yutaka; Kitamura, Toshio; Goyama, Susumu
err分享
err收藏
BRD9 determines the cell fate of hematopoietic stem cells by regulating chromatin state
errNATURE COMMUNICATIONS
IF15.7
err2023-12-15
err10
errOAAI
errXiao, Muran; Kondo, Shinji; Nomura, Masaki; Kato, Shinichiro; Nishimura, Koutarou; Zang, Weijia; Zhang, Yifan; Akashi, Tomohiro; Viny, Aaron; Shigehiro, Tsukasa; Ikawa, Tomokatsu; Yamazaki, Hiromi; Fukumoto, Miki; Tanaka, Atsushi; Hayashi, Yasutaka; Koike, Yui; Aoyama, Yumi; Ito, Hiromi; Nishikawa, Hiroyoshi; Kitamura, Toshio; Kanai, Akinori; Yokoyama, Akihiko; Fujiwara, Tohru; Goyama, Susumu; Noguchi, Hideki; Lee, Stanley C.; Toyoda, Atsushi; Hinohara, Kunihiko; Abdel-Wahab, Omar; Inoue, Daichi
err分享
err收藏
Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment有丝分裂扰动是地西他滨治疗髓系肿瘤的关键作用机制
errCELL REPORTS
IF6.9
err2023-09-01
err4
errOAAI
errYabushita, Tomohiro; Chinen, Takumi; Nishiyama, Atsuya; Asada, Shuhei; Shimura, Ruka; Isobe, Tomoya; Yamamoto, Keita; Sato, Naru; Enomoto, Yutaka; Tanaka, Yosuke; Fukuyama, Tomofusa; Satoh, Hitoshi; Kato, Keiko; Saitoh, Kaori; Ishikawa, Takamasa; Soga, Tomoyoshi; Nannya, Yasuhito; Fukagawa, Tatsuo; Nakanishi, Makoto; Kitagawa, Daiju; Kitamura, Toshio; Goyama, Susumu
err分享
err收藏
The E3 ligase DTX2 inhibits RUNX1 function by binding its C terminus and prevents the growth of RUNX1-dependent leukemia cellsE3连接酶DTX2通过结合其C末端抑制RUNX1功能并阻止RUNX1-dependent白血病细胞的生长
errFEBS JOURNAL
IF4.2
err2023-08-23
err3
errOAAI
errYonezawa, Taishi; Takahashi, Hirotaka; Hao, Yangying; Furukawa, Chie; Tsuchiya, Akiho; Zhang, Wenyu; Fukushima, Tsuyoshi; Fukuyama, Tomofusa; Sawasaki, Tatsuya; Kitamura, Toshio; Goyama, Susumu
err分享
err收藏
SETBP1 is dispensable for normal and malignant hematopoiesis
errLEUKEMIA
IF13.4
err2023-07-18
err3
errOAAI
errTanaka, Atsushi; Nishimura, Koutarou; Saika, Wataru; Kon, Ayana; Koike, Yui; Tatsumi, Hiromi; Takeda, June; Nomura, Masaki; Zang, Weijia; Nakayama, Manabu; Matsuda, Masashi; Yamazaki, Hiromi; Fukumoto, Miki; Ito, Hiromi; Hayashi, Yasutaka; Kitamura, Toshio; Kawamoto, Hiroshi; Takaori-Kondo, Akifumi; Koseki, Haruhiko; Ogawa, Seishi; Inoue, Daichi
err分享
err收藏
TLR7/8 stress response drives histiocytosis in SLC29A3 disordersTLR7/8应激反应驱动SLC29A3疾病中的组织细胞增生症
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2023-07-18
err8
errOAAI
errShibata, Takuma; Sato, Ryota; Taoka, Masato; Saitoh, Shin-Ichiroh; Komine, Mayumi; Yamaguchi, Kiyoshi; Goyama, Susumu; Motoi, Yuji; Kitaura, Jiro; Izawa, Kumi; Yamauchi, Yoshio; Tsukamoto, Yumiko; Ichinohe, Takeshi; Fujita, Etsuko; Hiranuma, Ryosuke; Fukui, Ryutaro; Furukawa, Yoichi; Kitamura, Toshio; Takai, Toshiyuki; Tojo, Arinobu; Ohtsuki, Mamitaro; Ohto, Umeharu; Shimizu, Toshiyuki; Ozawa, Manabu; Yoshida, Nobuaki; Isobe, Toshiaki; Latz, Eicke; Mukai, Kojiro; Taguchi, Tomohiko; Hemmi, Hiroaki; Akira, Shizuo; Miyake, Kensuke
err分享
err收藏
Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err394
errOAAI
errOnishi, M; Nosaka, T; Misawa, K; Mui, ALF; Gorman, D; McMahon, M; Miyajima, A; Kitamura, T
err分享
err收藏
Infertility with defective spermiogenesis in mice lacking AF5q31, the target of chromosomal translocation in human infant leukemia
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err29
errOAAI
errUrano, A; Endoh, M; Wada, T; Morikawa, Y; Itoh, M; Kataoka, Y; Taki, T; Akazawa, H; Nakajima, H; Komuro, I; Yoshida, N; Hayashi, Y; Handa, H; Kitamura, T; Nosaka, T
err分享
err收藏
Mammalian twisted gastrulation is essential for skeleto-lymphogenesis
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err86
errOAAI
errNosaka, T; Morita, S; Kitamura, H; Nakajima, H; Shibata, F; Morikawa, Y; Kataoka, Y; Ebihara, Y; Kawashima, T; Itoh, T; Ozaki, K; Senba, E; Tsuji, K; Makishima, F; Yoshida, N; Kitamura, T
err分享
err收藏

研究方向

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