Izumu Saito - Publications, H-index & Citations

Izumu Saito

Juntendo University Graduate School of Medicine

49H指数

180论文数

1.0W被引数

收录论文 36

发表时间

Adenovirus Vector-Mediated In Vivo Knock-in Treatment of Neonatal Phenylketonuria Mice Using Terminally Cleaved Donor DNA 腺病毒载体介导的在体基因敲入治疗新生苯丙酮尿症小鼠：使用末端切割的供体DNA

Journal of Gene Medicine

IF2.2

2026-09-30

OAAI

Megumi Yamaji; Hirotaka Tabata; Mariko Nakamura; Ryoko Fuse; Tadashi Okada; Shun-Ichi Ohba; Tomokazu Ohishi; Manabu Kawada; Izumu Saito; Shigeto Sato; Tomoko Nakanishi

Infection with measles virus induces leukopenia and rash in a humanized immune system mouse model 感染麻疹病毒在人类化免疫系统小鼠模型中诱导白细胞减少和皮疹

Scientific Reports

IF3.9

2026-08-12

OAAI

Tomoko Nakanishi; Misako Yoneda; Tomoko Fujiyuki; Yosuke Amagai; Izumu Saito; Chieko Kai

Disruption of Human Papillomavirus 16 E6/E7 Genes Using All-in-One Adenovirus Vectors Expressing Eight Double-Nicking Guide RNAs 使用表达八种双切割引导RNA的全一型腺病毒载体干扰人乳头瘤病毒16型E6/E7基因

International Journal of Molecular Sciences 2025, Vol. 26, Page 8685

IF4.9

2025-09-06

OAAI

Megumi Yamaji; Tomomi Nakahara; Tomoko Nakanishi; Satomi Aoyama-Kikawa; Kiyoshi Yamaguchi; Yoichi Furukawa; Mariko Nakamura; Tadashi Okada; Hirotaka Tabata; Ryoko Fuse; Eigo Shimizu; Rika Kasajima; Seiya Imoto; Iwao Kukimoto; Izumu Saito; Tohru Kiyono

Construction of adenovirus vectors simultaneously expressing four multiplex, double-nicking guide RNAs of CRISPR/Cas9 and in vivo genome editing

SCIENTIFIC REPORTS

IF3.9

2021-02-17

OAAI

Nakanishi, Tomoko; Maekawa, Aya; Suzuki, Mariko; Tabata, Hirotaka; Sato, Kumiko; Mori, Mai; Saito, Izumu

Highly multiplex guide RNA expression units of CRISPR/Cas9 were completely stable using cosmid amplification in a novel polygonal structure

JOURNAL OF GENE MEDICINE

IF2.2

2019-10-29

OAAI

Nakanishi, Tomoko; Maekawa, Aya; Tabata, Hirotaka; Yoshioka, Takashi; Pei, Zheng; Sato, Kumiko; Mori, Mai; Kato, Masaya; Saito, Izumu

Autophagy regulates lipid metabolism through selective turnover of NCoR1

NATURE COMMUNICATIONS

IF15.7

2019-04-05

154

OAAI

Saito, Tetsuya; Kuma, Akiko; Sugiura, Yuki; Ichimura, Yoshinobu; Obata, Miki; Kitamura, Hiroshi; Okuda, Shujiro; Lee, Hyeon-Cheol; Ikeda, Kazutaka; Kanegae, Yumi; Saito, Izumu; Auwerx, Johan; Motohashi, Hozumi; Suematsu, Makoto; Soga, Tomoyoshi; Yokomizo, Takehiko; Waguri, Satoshi; Mizushima, Noboru; Komatsu, Masaaki

Efficient genome replication of hepatitis B virus using adenovirus vector: a compact pregenomic RNA-expression unit

SCIENTIFIC REPORTS

IF3.9

2017-02-03

OAAI

Suzuki, Mariko; Kondo, Saki; Yamasaki, Manabu; Matsuda, Norie; Nomoto, Akio; Suzuki, Tetsuro; Saito, Izumu; Kanegae, Yumi

Single-domain intrabodies against hepatitis C virus core inhibit viral propagation and core-induced NFκB activation

JOURNAL OF GENERAL VIROLOGY

IF4.3

2016-04-01

OAAI

Suzuki, Ryosuke; Saito, Kenji; Matsuda, Mami; Sato, Mitsuru; Kanegae, Yumi; Shi, Guoli; Watashi, Koichi; Aizaki, Hideki; Chiba, Joe; Saito, Izumu; Wakita, Takaji; Suzuki, Tetsuro

Amphipathic α-Helices in Apolipoproteins Are Crucial to the Formation of Infectious Hepatitis C Virus Particles

PLOS PATHOGENS

IF4.9

2014-12-11

OAAI

Fukuhara, Takasuke; Wada, Masami; Nakamura, Shota; Ono, Chikako; Shiokawa, Mai; Yamamoto, Satomi; Motomura, Takashi; Okamoto, Toru; Okuzaki, Daisuke; Yamamoto, Masahiro; Saito, Izumu; Wakita, Takaji; Koike, Kazuhiko; Matsuura, Yoshiharu

Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B-positive structures

EMBO REPORTS

IF6.2

2014-03-25

OAAI

Lystad, Alf Hakon; Ichimura, Yoshinobu; Takagi, Kenji; Yang, Yinjie; Pankiv, Serhiy; Kanegae, Yumi; Kageyama, Shun; Suzuki, Mariko; Saito, Izumu; Mizushima, Tsunehiro; Komatsu, Masaaki; Simonsen, Anne

Adenovirus vectors lacking virus-associated RNA expression enhance shRNA activity to suppress hepatitis C virus replication

SCIENTIFIC REPORTS

IF3.9

2013-12-20

OAAI

Pei, Zheng; Shi, Guoli; Kondo, Saki; Ito, Masahiko; Maekawa, Aya; Suzuki, Mariko; Saito, Izumu; Suzuki, Tetsuro; Kanegae, Yumi

Efficient production of adenovirus vector lacking genes of virus-associated RNAs that disturb cellular RNAi machinery

SCIENTIFIC REPORTS

IF3.9

2013-01-25

OAAI

Maekawa, Aya; Pei, Zheng; Suzuki, Mariko; Fukuda, Hiromitsu; Ono, Yohei; Kondo, Saki; Saito, Izumu; Kanegae, Yumi

Keratinocyte Growth Factor Gene Transduction Ameliorates Pulmonary Fibrosis Induced by Bleomycin in Mice

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

IF5.3

2011-09-01

PREAI

Sakamoto, Seiko; Yazawa, Takuya; Baba, Yasuko; Sato, Hanako; Kanegae, Yumi; Hirai, Toyohiro; Saito, Izumu; Goto, Takahisa; Kurahashi, Kiyoyasu

BabA-mediated Adherence Is a Potentiator of the Helicobacter pylori Type IV Secretion System Activity BabA介导的粘附是幽门螺杆菌IV型分泌系统活性的增强剂

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2011-07-01

156

OAAI

Ishijima, Nozomi; Suzuki, Masato; Ashida, Hiroshi; Ichikawa, Yusuke; Kanegae, Yumi; Saito, Izumu; Boren, Thomas; Haas, Rainer; Sasakawa, Chihiro; Mimuro, Hitomi

High-level expression by tissue/cancer-specific promoter with strict specificity using a single-adenoviral vector

NUCLEIC ACIDS RESEARCH

IF13.1

2010-11-04

OAAI

Kanegae, Yumi; Terashima, Miho; Kondo, Saki; Fukuda, Hiromitsu; Maekawa, Aya; Pei, Zheng; Saito, Izumu

α-catenin is essential in intestinal adenoma formation

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2007-11-13

OAAI

Shibata, Hiroyuki; Takano, Hiroshi; Ito, Masaki; Shioya, Hisashi; Hirota, Morihisa; Matsumoto, Hiroshi; Kakudo, Yuichi; Ishioka, Chikashi; Akiyama, Tetsu; Kanegae, Yumi; Saito, Izumu; Noda, Tetsuo

Ductal origin of pancreatic adenocarcinomas induced by conditional activation of a human Ha-ras oncogene in rat pancreas

CARCINOGENESIS

IF2.9

2006-06-13

OAAI

Ueda, Shinobu; Fukamachi, Katsumi; Matsuoka, Yoichiro; Takasuka, Nobuo; Takeshita, Fumitaka; Naito, Akihiro; Iigo, Masaaki; Alexander, David B.; Moore, Malcolm A.; Saito, Izumu; Ochiya, Takahiro; Tsuda, Hiroyuki

Diverse DNA methylation statuses at alternative promoters of human genes in various tissues

DNA RESEARCH

IF2.9

2006-01-01

OAAI

Cheong, Jieun; Yamada, Yoichi; Yamashita, Riu; Irie, Takuma; Kanai, Akinori; Wakaguri, Hiroyuki; Nakai, Kenta; Ito, Takashi; Saito, Izumu; Sugano, Smuio; Suzuki, Yutaka

A database of recombinant viruses and recombinant viral vectors available from the RIKEN DNA bank 可从RIKEN DNA库获得的重组病毒和重组病毒载体数据库

JOURNAL OF GENE MEDICINE

IF2.2

2005-06-09

PREAI

Ugai, H; Murata, T; Nagamura, Y; Ugawa, Y; Suzuki, E; Nakata, H; Kujime, Y; Inamoto, S; Hirose, M; Inabe, K; Terashima, M; Yamasaki, T; Liu, BB; Nakade, K; Pan, JZ; Kimura, M; Saito, I; Hamada, H; Obata, Y; Yokoyama, KK

Ligand-independent signaling by overexpressed CD30 drives NF-κB activation in Hodgkin-Reed-Sternberg cells 通过过度表达的CD30驱动hodgkin-reed-sternberg细胞中nf-κb活化的配体非依赖性信号传导

ONCOGENE

IF7.3

2002-04-18

191

PREAI

Horie, R; Watanabe, T; Morishita, Y; Ito, K; Ishida, T; Kanegae, Y; Saito, I; Higashihara, M; Mori, S; Kadin, ME; Watanabe, T

研究方向