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收藏分享 收藏 分享 收藏 A Phase I/II Clinical Trial of Intradermal, Controllable Self-Replicating Ribonucleic Acid Vaccine EXG-5003 against SARS-CoV-2针对SARS-CoV-2的皮内，可控的自我复制核糖核酸疫苗EXG-5003的I/II期临床试验
Koseki, Takenao; Teramachi, Mayumi; Koga, Minako; Ko, Minoru S. H.; Amano, Tomokazu; Yu, Hong; Amano, Misa; Leyder, Erica; Badiola, Maria; Ray, Priyanka; Kim, Jiyoung; Ko, Akihiro C.; Achour, Achouak; Weng, Nan-ping; Imai, Takumi; Yoshida, Hisako; Taniuchi, Satsuki; Shintani, Ayumi; Fujigaki, Hidetsugu; Kondo, Masashi; Doi, Yohei 分享 收藏 SARS-CoV-2 infection establishes a stable and age-independent CD8+ T cell response against a dominant nucleocapsid epitope using restricted T cell receptorsChoy, Cecily; Chen, Joseph; Li, Jiangyuan; Gallagher, D. Travis; Lu, Jian; Wu, Daichao; Zou, Ainslee; Hemani, Humza; Baptiste, Beverly A.; Wichmann, Emily; Yang, Qian; Ciffelo, Jeffrey; Yin, Rui; Mckelvy, Julia; Melvin, Denise; Wallace, Tonya; Dunn, Christopher; Nguyen, Cuong; Chia, Chee W.; Fan, Jinshui; Ruffolo, Jeannie; Zukley, Linda; Shi, Guixin; Amano, Tomokazu; An, Yang; Meirelles, Osorio; Wu, Wells W.; Chou, Chao-Kai; Shen, Rong-Fong; Willis, Richard A.; Ko, Minoru S. H.; Liu, Yu-Tsueng; De, Supriyo; Pierce, Brian G.; Ferrucci, Luigi; Egan, Josephine; Mariuzza, Roy; Weng, Nan-Ping 分享 收藏 Functional and long-lived melanocytes from human pluripotent stem cells with transient ectopic expression of JMJD3具有JMJD3瞬时异位表达的人类多能干细胞的功能性和长寿命黑素细胞Kobori, Chie; Takagi, Ryo; Yokomizo, Ryo; Yoshihara, Sakie; Mori, Mai; Takahashi, Hiroto; Javaregowda, Palaksha Kanive; Akiyama, Tomohiko; Ko, Minoru S. H.; Kishi, Kazuo; Umezawa, Akihiro 分享 收藏 Klf4 cooperates with Oct3/4 and Sox2 to activate the Lefty1 core promoter in embryonic stem cellsKlf4与10月3/4和Sox2协同激活胚胎干细胞中的Lefty1核心启动子Nakatake, Yuhki; Fukui, Nobutaka; Iwamatsu, Yuko; Masui, Shinji; Takahashi, Kadue; Yagi, Rika; Yagi, Kiyohito; Miyazaki, Jun-ichi; Matoba, Ryo; Ko, Minoru S. H.; Niwa, Hitoshi 分享 收藏 Dax1 Binds to Oct3/4 and Inhibits Its Transcriptional Activity in Embryonic Stem CellsDax1与10月3/4结合并抑制其在胚胎干细胞中的转录活性Sun, Chuanhai; Nakatake, Yuhki; Akagi, Tadayuki; Ura, Hiroki; Matsuda, Takahiko; Nishiyama, Akira; Koide, Hiroshi; Ko, Minoru S. H.; Niwa, Hitoshi; Yokota, Takashi 分享 收藏 Unbiased, comprehensive analysis of Japanese health checkup data reveals a protective effect of light to moderate alcohol consumption on lung function对日本健康检查数据进行无偏见的综合分析，揭示了轻度至中度饮酒对肺功能的保护作用Makino, Kanako; Shimizu-Hirota, Ryoko; Goda, Norio; Hashimoto, Masahiro; Kawada, Ichiro; Kashiwagi, Kazuhiro; Hirota, Yasushi; Itoh, Hiroshi; Jinzaki, Masahiro; Iwao, Yasushi; Ko, Minoru; Ko, Shigeru; Takaishi, Hiromasa 分享 收藏 分享 收藏 Generation and Profiling of 2,135 Human ESC Lines for the Systematic Analyses of Cell States Perturbed by Inducing Single Transcription FactorsNakatake, Yuhki; Ko, Shigeru B. H.; Sharov, Alexei A.; Wakabayashi, Shunichi; Murakami, Miyako; Sakota, Miki; Chikazawa, Nana; Ookura, Chiaki; Sato, Saeko; Ito, Noriko; Ishikawa-Hirayama, Madoka; Mak, Siu Shan; Jakt, Lars Martin; Ueno, Tomoo; Hiratsuka, Ken; Matsushita, Misako; Goparaju, Sravan Kumar; Akiyama, Tomohiko; Ishiguro, Kei-ichiro; Oda, Mayumi; Gouda, Norio; Umezawa, Akihiro; Akutsu, Hidenori; Nishimura, Kunihiro; Matoba, Ryo; Ohara, Osamu; Ko, Minoru S. H. 分享 收藏 MEIOSIN Directs the Switch from Mitosis to Meiosis in Mammalian Germ CellsIshiguro, Kei-ichiro; Matsuura, Kumi; Tani, Naoki; Takeda, Naoki; Usuki, Shingo; Yamane, Mariko; Sugimoto, Michihiko; Fujimura, Sayoko; Hosokawa, Mihoko; Chuma, Shinichiro; Ko, Minoru S. H.; Araki, Kimi; Niwa, Hitoshi 分享 收藏 Induced Pluripotent Stem Cells Reprogrammed with Three Inhibitors Show Accelerated Differentiation Potentials with High Levels of 2-Cell Stage Marker ExpressionNishihara, Koji; Shiga, Takahiro; Nakamura, Eri; Akiyama, Tomohiko; Sasaki, Takashi; Suzuki, Sadafumi; Ko, Minoru S. H.; Tada, Norihiro; Okano, Hideyuki; Akamatsu, Wado 分享 收藏 Induction of human pluripotent stem cells into kidney tissues by synthetic mRNAs encoding transcription factorsHiratsuka, Ken; Monkawa, Toshiaki; Akiyama, Tomohiko; Nakatake, Yuhki; Oda, Mayumi; Goparaju, Sravan Kumar; Kimura, Hiromi; Chikazawa-Nohtomi, Nana; Sato, Saeko; Ishiguro, Keiichiro; Yamaguchi, Shintaro; Suzuki, Sayuri; Morizane, Ryuji; Ko, Shigeru B. H.; Itoh, Hiroshi; Ko, Minoru S. H. 分享 收藏 Establishment of a rapid and footprint-free protocol for differentiation of human embryonic stem cells into pancreatic endocrine cells with synthetic mRNAs encoding transcription factorsIda, Hideomi; Akiyama, Tomohiko; Ishiguro, Keiichiro; Goparaju, Sravan K.; Nakatake, Yuhki; Chikazawa-Nohtomi, Nana; Sato, Saeko; Kimura, Hiromi; Yokoyama, Yukihiro; Nagino, Masato; Ko, Minoru S. H.; Ko, Shigeru B. H. 分享 收藏 分享 收藏 Salt suppresses IFNγ inducible chemokines through the IFNγ-JAK1-STAT1 signaling pathway in proximal tubular cellsArai, Yohei; Takahashi, Daiei; Asano, Kenichi; Tanaka, Masato; Oda, Mayumi; Ko, Shigeru B. H.; Ko, Minoru S. H.; Mandai, Shintaro; Nomura, Naohiro; Rai, Tatemitsu; Uchida, Shinichi; Sohara, Eisei 分享 收藏 Rapid differentiation of human pluripotent stem cells into functional neurons by mRNAs encoding transcription factorsGoparaju, Sravan Kumar; Kohda, Kazuhisa; Ibata, Keiji; Soma, Atsumi; Nakatake, Yukhi; Akiyama, Tomohiko; Wakabayashi, Shunichi; Matsushita, Misako; Sakota, Miki; Kimura, Hiromi; Yuzaki, Michisuke; Ko, Shigeru B. H.; Ko, Minoru S. H. 分享 收藏 Epigenetic Manipulation Facilitates the Generation of Skeletal Muscle Cells from Pluripotent Stem CellsAkiyama, Tomohiko; Wakabayashi, Shunichi; Soma, Atsumi; Sato, Saeko; Nakatake, Yuhki; Oda, Mayumi; Murakami, Miyako; Sakota, Miki; Chikazawa-Nohtomi, Nana; Ko, Shigeru B. H.; Ko, Minoru S. H. 分享 收藏 Transient ectopic expression of the histone demethylase JMJD3 accelerates the differentiation of human pluripotent stem cellsleAkiyama, Tomohiko; Wakabayashi, Shunichi; Soma, Atsumi; Sato, Saeko; Nakatake, Yuhki; Oda, Mayumi; Murakami, Miyako; Sakota, Miki; Chikazawa-Nohtomi, Nana; Ko, Shigeru B. H.; Ko, Minoru S. H. 分享 收藏 
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