Hugues Aschard - Publications, H-index & Citations

Hugues Aschard

pasteur institute

45H指数

212论文数

1.3W被引数

收录论文 70

发表时间

A versatile multi-components mixed model for bacterial-Genome Wide association studies 一种用于细菌全基因组关联研究的通用多组分混合模型

Nature Communications

IF15.7

2026-05-07

OAAI

Arthur Frouin; Fabien Laporte; Lukas Hafner; Mylène Maury; Zachary R. McCaw; Hanna Julienne; Léo Henches; Alexandre Leclercq; Rayan Chikhi; Marc Lecuit; Hugues Aschard

The influence of environment on bacterial co-abundance in the gut microbiomes of healthy human individuals 环境对健康人类个体肠道微生物组中细菌共丰度的影响

Communications Biology

IF5.1

2025-11-06

OAAI

Christophe Boetto; Violeta Basten Romero; Léo Henches; Arthur Frouin; Antoine Auvergne; Etienne Patin; Marius Bredon; Sean P. Kennedy; Darragh Duffy; Lluis Quintana-Murci; Harry Sokol; Hugues Aschard

Unraveling shared genetics across asthma subtypes and 81 asthma-related traits 解析哮喘亚型及81种哮喘相关性状的共享遗传学

Journal of Allergy and Clinical Immunology

IF11.2

2025-09-12

PREAI

Raphaël Vernet; Christophe Linhard; Anja Estermann; Yuka Suzuki; Florence Demenais; Hugues Aschard; Hanna Julienne; Emmanuelle Bouzigon

Polygenic risk score prediction accuracy convergence 多基因风险评分预测准确性的收敛

Human Genetics and Genomics Advances

IF3.6

2025-05-14

OAAI

Léo Henches; Jihye Kim; Zhiyu Yang; Simone Rubinacci; Gabriel Pires; Clara Albiñana; Christophe Boetto; Hanna Julienne; Arthur Frouin; Antoine Auvergne; Yuka Suzuki; Sarah Djebali; Olivier Delaneau; Andrea Ganna; Bjarni Vilhjálmsson; Florian Privé; Hugues Aschard

Pitfalls in performing genome-wide association studies on ratio traits 对比率性状进行全基因组关联研究的陷阱

HUMAN GENETICS AND GENOMICS ADVANCES

IF3.6

2025-04-01

OAAI

Mccaw, Zachary R.; Dey, Rounak; Somineni, Hari; Amar, David; Mukherjee, Sumit; Sandor, Kaitlin; Karaletsos, Theofanis; Koller, Daphne; Aschard, Hugues; Smith, George Davey; Macarthur, Daniel; O'Dushlaine, Colm; Soare, Thomas W.

Identifying chronic obstructive pulmonary disease subtypes using multi-trait genetics 利用多性状遗传学识别慢性阻塞性肺疾病亚型

EBIOMEDICINE

IF10.8

2025-03-01

PREAI

Ziyatdinov, Andrey; Hobbs, Brian D.; Kanaan-Izquierdo, Samir; Moll, Matthew; Sakornsakolpat, Phuwanat; Shrine, Nick; Chen, Jing; Song, Kijoung; Bowler, Russell P.; Castaldi, Peter J.; Tobin, Martin D.; Kraft, Peter; Silverman, Edwin K.; Julienne, Hanna; Cho, Michael H.; Aschard, Hugues

Does Age Modify the Relation Between Genetic Predisposition to Glaucoma and Various Glaucoma Traits in the UK Biobank?

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2025-02-21

OAAI

Kim, Jihye; Kang, Jae H.; Wiggs, Janey L.; Zhao, Hetince; Li, Keva; Zebardast, Nazlee; Segre, Ayellet; Friedman, David S.; Do, Ron; Khawaja, Anthony P.; Aschard, Hugues; Pasquale, Louis R.

Multitrait Analysis to Decipher the Intertwined Genetic Architecture of Neuroanatomical Phenotypes and Psychiatric Disorders 多性状分析以阐明神经解剖表型与精神障碍错综复杂的遗传结构

biological psychiatry cognitive neuroscience and neuroimaging

IF0

2024-09-10

OAAI

Antoine Auvergne; Nicolas Traut; Léo Henches; Lucie Troubat; Arthur Frouin; Christophe Boetto; Sayeh Kazem; Hanna Julienne; Roberto Toro; Hugues Aschard

Genome-wide discovery for biomarkers using quantile regression at biobank scale

NATURE COMMUNICATIONS

IF15.7

2024-07-31

OAAI

Wang, Chen; Wang, Tianying; Kiryluk, Krzysztof; Wei, Ying; Aschard, Hugues; Ionita-Laza, Iuliana

Trait selection strategy in multi-trait GWAS: Boosting SNP discoverability

HUMAN GENETICS AND GENOMICS ADVANCES

IF3.6

2024-07-01

OAAI

Suzuki, Yuka; Menagar, Herve; Brancotte, Bryan; Vernet, Raphael; Nerin, Cyril; Boetto, Christophe; Auvergne, Antoine; Linhard, Christophe; Torchet, Rachel; Lechat, Pierre; Troubat, Lucie; Cho, Michael H.; Bouzigon, Emmanuelle; Aschard, Hugues; Julienne, Hanna

MANOCCA: a robust and computationally efficient test of covariance in high-dimension multivariate omics data

BRIEFINGS IN BIOINFORMATICS

IF7.7

2024-06-10

OAAI

Boetto, Christophe; Frouin, Arthur; Henches, Leo; Auvergne, Antoine; Suzuki, Yuka; Patin, Etienne; Bredon, Marius; Chiu, Alec; Sankararaman, Sriram; Zaitlen, Noah; Kennedy, Sean P.; Quintana-Murci, Lluis; Duffy, Darragh; Sokol, Harry; Aschard, Hugues

An approach to identify gene-environment interactions and reveal new biological insight in complex traits

NATURE COMMUNICATIONS

IF15.7

2024-04-22

OAAI

Zhu, Xiaofeng; Yang, Yihe; Lorincz-Comi, Noah; Li, Gen; Bentley, Amy R.; de Vries, Paul S.; Brown, Michael; Morrison, Alanna C.; Rotimi, Charles N.; Gauderman, W. James; Rao, Dabeeru C.; Aschard, Hugues

Multi-trait GWAS for diverse ancestries: mapping the knowledge gap 针对不同祖先的多特征gis: 绘制知识差距

BMC GENOMICS

IF3.7

2024-04-17

OAAI

Troubat, Lucie; Fettahoglu, Deniz; Henches, Leo; Aschard, Hugues; Julienne, Hanna

Polygenic risk scores identify heterogeneity in asthma and chronic obstructive pulmonary disease 多基因风险评分确定哮喘和慢性阻塞性肺疾病的异质性

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IF11.2

2023-12-01

PREAI

Moll, Matthew; Sordillo, Joanne E.; Ghosh, Auyon J.; Hayden, Lystra P.; McDermott, Gregory; McGeachie, Michael J.; Dahlin, Amber; Tiwari, Anshul; Manmadkar, Monica G.; Abston, Eric D.; Pavuluri, Chandan; Saferali, Aabida; Begum, Sofina; Ziniti, John P.; Gulsvik, Amund; Bakke, Per S.; Aschard, Hugues; Iribarren, Carlos; Hersh, Craig P.; Sparks, Jeffrey A.; Hobbs, Brian D.; Lasky-Su, Jessica A.; Silverman, Edwin K.; Weiss, Scott T.; Wu, Ann Chen; Cho, Michael H.

The Association of Physical Activity with Glaucoma and Related Traits in the UK Biobank 英国生物库中体力活动与青光眼及相关特征的关联

OPHTHALMOLOGY

IF9.5

2023-10-01

OAAI

Madjedi, Kian M.; Stuart, Kelsey V.; Chua, Sharon Y. L.; Ramulu, Pradeep Y.; Warwick, Alasdair; Luben, Robert N.; Sun, Zihan; Chia, Mark A.; Aschard, Hugues; Wiggs, Janey L.; Kang, Jae H.; Pasquale, Louis R.; Foster, Paul J.; Khawaja, Anthony P.

Multi-PGS enhances polygenic prediction by combining 937 polygenic scores 多PGS通过组合937多基因得分来增强多基因预测

NATURE COMMUNICATIONS

IF15.7

2023-08-05

OAAI

Albinana, Clara; Zhu, Zhihong; Schork, Andrew J.; Ingason, Andres; Aschard, Hugues; Brikell, Isabell; Bulik, Cynthia M.; Petersen, Liselotte V.; Agerbo, Esben; Grove, Jakob; Nordentoft, Merete; Hougaard, David M.; Werge, Thomas; Borglum, Anders D.; Mortensen, Preben Bo; McGrath, John J.; Neale, Benjamin M.; Prive, Florian; Vilhjalmsson, Bjarni J.

A high-throughput sequencing approach identifies immunotherapeutic targets for bacterial meningitis in neonates

EBIOMEDICINE

IF10.8

2023-02-01

OAAI

Pons, Stephanie; Frapy, Eric; Sereme, Youssouf; Gaultier, Charlotte; Lebreton, Francois; Kropec, Andrea; Danilchanka, Olga; Schlemmer, Laura; Schrimpf, Cecile; Allain, Margaux; Angoulvant, Francois; Lecuyer, Herve; Bonacorsi, Stephane; Aschard, Hugues; Sokol, Harry; Cywes-Bentley, Colette; Mekalanos, John J.; Guillard, Thomas; Pier, Gerald B.; Roux, Damien; Skurnik, David

Identifying and correcting for misspecifications in GWAS summary statistics and polygenic scores

HUMAN GENETICS AND GENOMICS ADVANCES

IF3.6

2022-10-01

OAAI

Prive, Florian; Arbel, Julyan; Aschard, Hugues; Vilhjalmsson, Bjarni J.

Cytokine Profiling of Amniotic Fluid from Congenital Cytomegalovirus Infection

VIRUSES-BASEL

IF3.5

2022-09-28

OAAI

Bourgon, Nicolas; Fitzgerald, Wendy; Aschard, Hugues; Magny, Jean-Francois; Guilleminot, Tiffany; Stirnemann, Julien; Romero, Roberto; Ville, Yves; Margolis, Leonid; Leruez-Ville, Marianne

The Association between Serum Lipids and Intraocular Pressure in 2 Large United Kingdom Cohorts

OPHTHALMOLOGY

IF9.5

2022-09-01

OAAI

Madjedi, Kian M.; Stuart, Kelsey, V; Chua, Sharon Y. L.; Luben, Robert N.; Warwick, Alasdair; Pasquale, Louis R.; Kang, Jae H.; Wiggs, Janey L.; Lentjes, Marleen A. H.; Aschard, Hugues; Sattar, Naveed; Foster, Paul J.; Khawaja, Anthony P.

研究方向