José Luis Gómez-Skármeta

CSIC and Universidad Pablo de Olavide and Junta de Andalucia

61H指数

235论文数

1.2W被引数

收录论文 93

发表时间

CTCF delimits a DNA methylation transition at the intergenic region between the embryonic and adult α-globin genes CTCF在胚胎和成人α-珠蛋白基因之间的基因间区域限定了DNA甲基化转变

Epigenetics

IF3.2

2026-08-03

OAAI

Gustavo Tapia-Urzúa; Hober Nelson Núñez-Martínez; Sylvia Garza-Manero; Martin Franke; Carlos Alberto Peralta-Alvarez; Ángel Josué Cerecedo-Castillo; Georgina Guerrero; José Luis Gómez-Skarmeta; Félix Recillas-Targa

Deep conservation of cis-regulatory elements and chromatin organization in echinoderms uncover ancestral regulatory features of animal genomes 棘皮动物中顺式调控元件和染色质组织的深度保守揭示了动物基因组祖先的调控特征

Nature Ecology & Evolution

IF14.5

2026-01-07

PREAI

Marta S. Magri; Danila Voronov; Saoirse Foley; Pedro Manuel Martínez-García; Martin Franke; Gregory A. Cary; José M. Santos-Pereira; Claudia Cuomo; Manuel Fernández-Moreno; Marta Portela; Alejandro Gil-Galvez; Rafael D. Acemel; Periklis Paganos; Carolyn Ku; Jovana Ranđelović; Maria Lorenza Rusciano; Panos N. Firbas; José Luis Gómez-Skarmeta; Veronica F. Hinman; Maria Ina Arnone; Ignacio Maeso

Hemichordate cis-regulatory genomics and the gene expression dynamics of deuterostomes

NATURE ECOLOGY & EVOLUTION

IF14.5

2024-10-18

OAAI

Perez-Posada, Alberto; Lin, Che-Yi; Fan, Tzu-Pei; Lin, Ching-Yi; Chen, Yi-Chih; Gomez-Skarmeta, Jose Luis; Yu, Jr-Kai; Su, Yi-Hsien; Tena, Juan J.

Integrative multi-omics increase resolution of the sea urchin posterior gut gene regulatory network at single-cell level

DEVELOPMENT

IF3.6

2024-08-29

OAAI

Voronov, Danila; Paganos, Periklis; Magri, Marta S.; Cuomo, Claudia; Maeso, Ignacio; Gomez-Skarmeta, Jose Luis; Arnone, Maria Ina

An amphioxus neurula stage cell atlas supports a complex scenario for the emergence of vertebrate head mesoderm

NATURE COMMUNICATIONS

IF15.7

2024-05-29

OAAI

Grau-Bove, Xavier; Subirana, Lucie; Meister, Lydvina; Soubigou, Anael; Neto, Ana; Elek, Anamaria; Naranjo, Silvia; Fornas, Oscar; Gomez-Skarmeta, Jose Luis; Tena, Juan J.; Irimia, Manuel; Bertrand, Stephanie; Sebe-Pedros, Arnau; Escriva, Hector

Comparative 3D genome analysis between neural retina and retinal pigment epithelium reveals differential cis-regulatory interactions at retinal disease loci

GENOME BIOLOGY

IF9.4

2024-05-17

OAAI

D'haene, Eva; Lopez-Soriano, Victor; Martinez-Garcia, Pedro Manuel; Kalayanamontri, Soraya; Rey, Alfredo Duenas; Sousa-Ortega, Ana; Naranjo, Silvia; Van de Sompele, Stijn; Vantomme, Lies; Mahieu, Quinten; Vergult, Sarah; Neto, Ana; Gomez-Skarmeta, Jose Luis; Martinez-Morales, Juan Ramon; Bauwens, Miriam; Tena, Juan Jesus; De Baere, Elfride

Wnt/β-catenin signalling is required for pole-specific chromatin remodeling during planarian regeneration

NATURE COMMUNICATIONS

IF15.7

2023-01-18

OAAI

Pascual-Carreras, Eudald; Marin-Barba, Marta; Castillo-Lara, Sergio; Coronel-Cordoba, Pablo; Magri, Marta Silvia; Wheeler, Grant N.; Gomez-Skarmeta, Jose Luis; Abril, Josep F.; Salo, Emili; Adell, Teresa

Active DNA demethylation of developmental cis-regulatory regions predates vertebrate origins

SCIENCE ADVANCES

IF12.5

2022-12-02

OAAI

Skvortsova, Ksenia; Bertrand, Stephanie; Voronov, Danila; Duckett, Paul E.; Ross, Samuel E.; Magri, Marta Silvia; Maeso, Ignacio; Weatheritt, Robert J.; Skarmeta, Jose Luis Gomez; Arnone, Maria Ina; Escriva, Hector; Bogdanovic, Ozren

Parallel evolution of amphioxus and vertebrate small-scale gene duplications

GENOME BIOLOGY

IF9.4

2022-11-18

OAAI

Braso-Vives, Marina; Marletaz, Ferdinand; Echchiki, Amina; Mantica, Federica; Acemel, Rafael D.; Gomez-Skarmeta, Jose L.; Hartasanchez, Diego A.; Le Targa, Lorlane; Pontarotti, Pierre; Tena, Juan J.; Maeso, Ignacio; Escriva, Hector; Irimia, Manuel; Robinson-Rechavi, Marc

Multi-omics approach dissects cis-regulatory mechanisms underlying North Carolina macular dystrophy, a retinal enhanceropathy

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2022-11-01

OAAI

van de Sompele, Stijn; Small, Kent W.; Cicekdal, Munevver Burcu; Soriano, Victor Lopez; D'haene, Eva; Shaya, Fadi S.; Agemy, Steven; van der Snickt, Thijs; Rey, Alfredo Duenas; Rosseel, Toon; Van Heetvelde, Mattias; Vergult, Sarah; Balikova, Irina; Bergen, Arthur A.; Boon, Camiel J. F.; De Zaeytijd, Julie; Inglehearn, Chris F.; Kousal, Bohdan; Leroy, Bart P.; Rivolta, Carlo; Vaclavik, Veronika; van den Ende, Jenneke; van Schooneveld, Mary J.; Gomez-Skarmeta, Jose Luis; Tena, Juan J.; Martinez-Morales, Juan R.; Liskova, Petra; Vleminckx, Kris; De Baere, Elfride

Pluripotency factors regulate the onset of Hox cluster activation in the early embryo

SCIENCE ADVANCES

IF12.5

2022-07-15

OAAI

Tiana, Maria; Lopez-Jimenez, Elena; Sainz de Aja, Julio; Barral, Antonio; Victorino, Jesus; Badia-Careaga, Claudio; Rollan, Isabel; Rouco, Raquel; Santos, Elisa; Sanchez-Iranzo, Hector; Acemel, Rafael D.; Torroja, Carlos; Adan, Javier; Andres-Leon, Eduardo; Luis Gomez-Skarmeta, Jose; Giovinazzo, Giovanna; Sanchez-Cabo, Fatima; Manzanares, Miguel

Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements

NATURE GENETICS

IF31.8

2022-07-04

OAAI

Baranasic, Damir; Hortenhuber, Matthias; Balwierz, Piotr J.; Zehnder, Tobias; Mukarram, Abdul Kadir; Nepal, Chirag; Varnai, Csilla; Hadzhiev, Yavor; Jimenez-Gonzalez, Ada; Li, Nan; Wragg, Joseph; D'Orazio, Fabio M.; Relic, Dorde; Pachkov, Mikhail; Diaz, Noelia; Hernandez-Rodriguez, Benjamin; Chen, Zelin; Stoiber, Marcus; Dong, Michael; Stevens, Irene; Ross, Samuel E.; Eagle, Anne; Martin, Ryan; Obasaju, Oluwapelumi; Rastegar, Sepand; McGarvey, Alison C.; Kopp, Wolfgang; Chambers, Emily; Wang, Dennis; Kim, Hyejeong R.; Acemel, Rafael D.; Naranjo, Silvia; Lapinski, Maciej; Chong, Vanessa; Mathavan, Sinnakaruppan; Peers, Bernard; Sauka-Spengler, Tatjana; Vingron, Martin; Carninci, Piero; Ohler, Uwe; Lacadie, Scott Allen; Burgess, Shawn M.; Winata, Cecilia; van Eeden, Freek; Vaquerizas, Juan M.; Luis Gomez-Skarmeta, Jose; Onichtchouk, Daria; Brown, Ben James; Bogdanovic, Ozren; van Nimwegen, Erik; Westerfield, Monte; Wardle, Fiona C.; Daub, Carsten O.; Lenhard, Boris; Muller, Ferenc

Regulatory Architecture of the RCA Gene Cluster Captures an Intragenic TAD Boundary, CTCF-Mediated Chromatin Looping and a Long-Range Intergenic Enhancer

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-06-13

OAAI

Cheng, Jessica; Clayton, Joshua S.; Acemel, Rafael D.; Zheng, Ye; Taylor, Rhonda L.; Keles, Sunduz; Franke, Martin; Boackle, Susan A.; Harley, John B.; Quail, Elizabeth; Gomez-Skarmeta, Jose Luis; Ulgiati, Daniela

MacroH2As regulate enhancer-promoter contacts affecting enhancer activity and sensitivity to inflammatory cytokines

CELL REPORTS

IF6.9

2022-06-01

OAAI

Corujo, David; Malinverni, Roberto; Carrillo-Reixach, Juan; Meers, Oliver; Garcia-Jaraquemada, Arce; Le Pannerer, Marguerite-Marie; Valero, Vanesa; Perez, Ainhoa; Del Rio-Alvarez, Alvaro; Royo, Laura; Perez-Gonzalez, Beatriz; Raurell, Helena; Acemel, Rafael D.; Santos-Pereira, Jose M.; Garrido-Pontnou, Marta; Luis Gomez-Skarmeta, Jose; Pasquali, Lorenzo; Manye, Josep; Armengol, Carolina; Buschbeck, Marcus

Multidimensional chromatin profiling of zebrafish pancreas to uncover and investigate disease-relevant enhancers

NATURE COMMUNICATIONS

IF15.7

2022-04-11

OAAI

Bordeira-Carrico, Renata; Teixeira, Joana; Duque, Marta; Galhardo, Mafalda; Ribeiro, Diogo; Acemel, Rafael D.; Firbas, Panos N.; Tena, Juan J.; Eufrasio, Ana; Marques, Joana; Ferreira, Fabio J.; Freitas, Telmo; Carneiro, Fatima; Gomez-Skarmeta, Jose Luis; Bessa, Jose

Duplications disrupt chromatin architecture and rewire GPR101-enhancer communication in X-linked acrogigantism

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2022-04-01

OAAI

Franke, Martin; Daly, Adrian F.; Palmeira, Leonor; Tirosh, Amit; Stigliano, Antonio; Trifan, Eszter; Faucz, Fabio R.; Abboud, Dayana; Petrossians, Patrick; Tena, Juan J.; Vitali, Eleonora; Lania, Andrea G.; Gomez-Skarmeta, Jose L.; Beckers, Albert; Stratakis, Constantine A.; Trivellin, Giampaolo

Gene Regulatory Networks of Epidermal and Neural Fate Choice in a Chordate

MOLECULAR BIOLOGY AND EVOLUTION

IF5.3

2022-03-11

OAAI

Leon, Anthony; Subirana, Lucie; Magre, Kevin; Cases, Ildefonso; Tena, Juan J.; Irimia, Manuel; Gomez-Skarmeta, Jose Luis; Escriva, Hector; Bertrand, Stephanie

Gain of gene regulatory network interconnectivity at the origin of vertebrates

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-03-09

OAAI

Gil-Galvez, Alejandro; Jimenez-Gancedo, Sandra; Perez-Posada, Alberto; Franke, Martin; Acemel, Rafael D.; Lin, Che-Yi; Chou, Cindy; Su, Yi-Hsien; Yu, Jr-Kai; Bertrand, Stephanie; Schubert, Michael; Escriva, Hector; Tena, Juan J.; Luis Gomez-Skarmeta, Jose

The Shh/Gli3 gene regulatory network precedes the origin of paired fins and reveals the deep homology between distal fins and digits

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-11-08

OAAI

Letelier, Joaquin; Naranjo, Silvia; Sospedra-Arrufat, Ismael; Ramon Martinez-Morales, Juan; Lopez-Rios, Javier; Shubin, Neil; Luis Gomez-Skarmeta, Jose

Asthma-associated genetic variants induce IL33 differential expression through an enhancer-blocking regulatory region

NATURE COMMUNICATIONS

IF15.7

2021-10-21

OAAI

Aneas, Ivy; Decker, Donna C.; Howard, Chanie L.; Sobreira, Debora R.; Sakabe, Noboru J.; Blaine, Kelly M.; Stein, Michelle M.; Hrusch, Cara L.; Montefiori, Lindsey E.; Tena, Juan; Magnaye, Kevin M.; Clay, Selene M.; Gern, James E.; Jackson, Daniel J.; Altman, Matthew C.; Naureckas, Edward T.; Hogarth, Douglas K.; White, Steven R.; Luis Gomez-Skarmeta, Jose; Schoetler, Nathan; Ober, Carole; Sperling, Anne, I; Nobrega, Marcelo A.

研究方向