未登录 Effect of chronic mucus hypersecretion on treatment responses to inhaled therapies in patients with chronic obstructive pulmonary disease: Post hoc analysis of the IMPACT trial 慢性黏液高分泌对慢性阻塞性肺疾病患者吸入治疗反应的影响: IMPACT试验的事后分析 Thompson, Philip J.; Criner, Gerard J.; Dransfield, Mark T.; Halpin, David M. G.; Han, MeiLan K.; Lipson, David A.; Maghzal, Ghassan J.; Martinez, Fernando J.; Midwinter, Dawn; Singh, Dave; Tombs, Lee; Wise, Robert A. 分享 收藏
Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4 Grosche, Sarah; Marenholz, Ingo; Esparza-Gordillo, Jorge; Arnau-Soler, Aleix; Pairo-Castineira, Erola; Rueschendorf, Franz; Ahluwalia, Tarunveer S.; Almqvist, Catarina; Arnold, Andreas; Baurecht, Hansjoerg; Bisgaard, Hans; Bonnelykke, Klaus; Brown, Sara J.; Bustamante, Mariona; Curtin, John A.; Custovic, Adnan; Dharmage, Shyamali C.; Esplugues, Ana; Falchi, Mario; Fernandez-Orth, Dietmar; Ferreira, Manuel A. R.; Franke, Andre; Gerdes, Sascha; Gieger, Christian; Hakonarson, Hakon; Holt, Patrick G.; Homuth, Georg; Hubner, Norbert; Hysi, Pirro G.; Jarvelin, Marjo-Riitta; Karlsson, Robert; Koppelman, Gerard H.; Lau, Susanne; Lutz, Manuel; Magnusson, Patrik K. E.; Marks, Guy B.; Mueller-Nurasyid, Martina; Noethen, Markus M.; Paternoster, Lavinia; Pennell, Craig E.; Peters, Annette; Rawlik, Konrad; Robertson, Colin F.; Rodriguez, Elke; Sebert, Sylvain; Simpson, Angela; Sleiman, Patrick M. A.; Standl, Marie; Stoelzl, Dora; Strauch, Konstantin; Szwajda, Agnieszka; Tenesa, Albert; Thompson, Philip J.; Ullemar, Vilhelmina; Visconti, Alessia; Vonk, Judith M.; Wang, Carol A.; Weidinger, Stephan; Wielscher, Matthias; Worth, Catherine L.; Xu, Chen-Jian; Lee, Young-Ae 分享 收藏
Reduced SOCS1 Expression in Lung Fibroblasts from Patients with IPF Is Not Mediated by Promoter Methylation or Mir155 Prele, Cecilia M.; Iosifidis, Thomas; McAnulty, Robin J.; Pearce, David R.; Badrian, Bahareh; Miles, Tylah; Jamieson, Sarra E.; Ernst, Matthias; Thompson, Philip J.; Laurent, Geoffrey J.; Knight, Darryl A.; Mutsaers, Steven E. 分享 收藏
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Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis (vol 50, pg 1072, 2018) 全基因组关联和HLA精细定位研究确定了过敏性鼻炎的风险位点和遗传途径 (第50卷，1072页，2018) Waage, Johannes; Standl, Marie; Curtin, John A.; Jessen, Leon E.; Thorsen, Jonathan; Tian, Chao; Schoettler, Nathan; Flores, Carlos; Abdellaoui, Abdel; Ahluwalia, Tarunveer S.; Alves, Alexessander C.; Amaral, Andre F. S.; Anto, Josep M.; Arnold, Andreas; Barreto-Luis, Amalia; Baurecht, Hansjorg; van Beijsterveldt, Catharina E. M.; Bleecker, Eugene R.; Bonas-Guarch, Silvia; Boomsma, Dorret I.; Brix, Susanne; Bunyavanich, Supinda; Burchard, Esteban G.; Chen, Zhanghua; Curjuric, Ivan; Custovic, Adnan; den Dekker, Herman T.; Dharmage, Shyamali C.; Dmitrieva, Julia; Duijts, Liesbeth; Ege, Markus J.; Gauderman, W. James; Georges, Michel; Gieger, Christian; Gilliland, Frank; Granell, Raquel; Gui, Hongsheng; Hansen, Torben; Heinrich, Joachim; Henderson, John; Hernandez-Pacheco, Natalia; Holt, Patrick; Imboden, Medea; Jaddoe, Vincent W. V.; Jarvelin, Marjo-Riitta; Jarvis, Deborah L.; Jensen, Kamilla K.; Jonsdottir, Ingileif; Kabesch, Michael; Kaprio, Jaakko; Kumar, Ashish; Lee, Young-Ae; Levin, Albert M.; Li, Xingnan; Lorenzo-Diaz, Fabian; Melen, Erik; Mercader, Josep M.; Meyers, Deborah A.; Myers, Rachel; Nicolae, Dan L.; Nohr, Ellen A.; Palviainen, Teemu; Paternoster, Lavinia; Pennell, Craig E.; Pershagen, Goran; Pino-Yanes, Maria; Probst-Hensch, Nicole M.; Ruschendorf, Franz; Simpson, Angela; Stefansson, Kari; Sunyer, Jordi; Sveinbjornsson, Gardar; Thiering, Elisabeth; Thompson, Philip J.; Torrent, Maties; Torrents, David; Tung, Joyce Y.; Wang, Carol A.; Weidinger, Stephan; Weiss, Scott; Willemsen, Gonneke; Williams, L. Keoki; Ober, Carole; Hinds, David A.; Ferreira, Manuel A.; Bisgaard, Hans; Strachan, David P.; Bonnelykke, Klaus 分享 收藏
Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis 全基因组关联和HLA精细定位研究确定了变应性鼻炎的风险位点和遗传途径 Waage, Johannes; Standl, Marie; Curtin, John A.; Jessen, Leon E.; Thorsen, Jonathan; Tian, Chao; Schoettler, Nathan; Flores, Carlos; Abdellaoui, Abdel; Ahluwalia, Tarunveer S.; Alves, Alexessander C.; Amaral, Andre F. S.; Anto, Josep M.; Arnold, Andreas; Barreto-Luis, Amalia; Baurecht, Hansjoerg; van Beijsterveldt, Catharina E. M.; Bleecker, Eugene R.; Bonas-Guarch, Silvia; Boomsman, Dorret I.; Brix, Susanne; Bunyavanich, Supinda; Burchard, Esteban G.; Chen, Zhanghua; Curjuric, Ivan; Custovic, Adnan; den Dekker, Herman T.; Dharmage, Shyamali C.; Dmitrieva, Julia; Duijts, Liesbeth; Ege, Markus J.; Gauderman, W. James; Georges, Michel; Gieger, Christian; Gilliland, Frank; Granell, Raquel; Gui, Hongsheng; Hansen, Torben; Heinrich, Joachim; Henderson, John; Hernandez-Pacheco, Natalia; Holt, Patrick; Imboden, Medea; Jaddoe, Vincent W. V.; Jarvelin, Marjo-Riitta; Jarvis, Deborah L.; Jensen, Kamilla K.; Jonsdottir, Ingileif; Kabesch, Michael; Kaprio, Jaakko; Kumar, Ashish; Lee, Young-Ae; Levin, Albert M.; Li, Xingnan; Lorenzo-Diaz, Fabian; Melen, Erik; Mercader, Josep M.; Meyers, Deborah A.; Myers, Rachel; Nicolae, Dan L.; Nohr, Ellen A.; Palviainen, Teemu; Paternoster, Lavinia; Pennell, Craig E.; Pershagen, Goran; Pino-Yanes, Maria; Probst-Hensch, Nicole M.; Ruschendorf, Franz; Simpson, Angela; Stefansson, Kari; Sunyer, Jordi; Sveinbjornsson, Gardar; Thiering, Elisabeth; Thompson, Philip J.; Torrent, Maties; Torrents, David; Tung, Joyce Y.; Wang, Carol A.; Weidinger, Stephan; Weiss, Scott; Willemsen, Gonneke; Williams, L. Keoki; Ober, Carole; Hinds, David A.; Ferreira, Manuel A.; Bisgaard, Hans; Strachan, David P.; Bonnelykke, Klaus 分享 收藏
Airway Interleukin-33 and type 2 cytokines in adult patients with acute asthma Poulsen, Nadia Nicholine; Bjerregaard, Asger; Khoo, Siew-Kim; Laing, Ingrid A.; Le Souef, Peter; Backer, Vibeke; Rapley, Laura; Cohen, Suzanne E.; Barrett, Lucy; Thompson, Philip; Baltic, Svetlana; Porsbjerg, Celeste 分享 收藏
Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks Demenais, Florence; Margaritte-Jeannin, Patricia; Barnes, Kathleen C.; Cookson, William O. C.; Altmueller, Janine; Ang, Wei; Barr, R. Graham; Beaty, Terri H.; Becker, Allan B.; Beilby, John; Bisgaard, Hans; Bjornsdottir, Unnur Steina; Bleecker, Eugene; Bonnelykke, Klaus; Boomsma, Dorret I.; Bouzigon, Emmanuelle; Brightling, Christopher E.; Brossard, Myriam; Brusselle, Guy G.; Burchard, Esteban; Burkart, Kristin M.; Bush, Andrew; Chan-Yeung, Moira; Chung, Kian Fan; Alves, Alexessander Couto; Curtin, John A.; Custovic, Adnan; Daley, Denise; de Jongste, Johan C.; Del-Rio-Navarro, Blanca E.; Donohue, Kathleen M.; Duijts, Liesbeth; Eng, Celeste; Eriksson, Johan G.; Farrall, Martin; Fedorova, Yuliya; Feenstra, Bjarke; Ferreira, Manuel A.; Freidin, Maxim B.; Gajdos, Zofia; Gauderman, Jim; Gehring, Ulrike; Geller, Frank; Genuneit, Jon; Gharib, Sina A.; Gilliland, Frank; Granell, Raquel; Graves, Penelope E.; Gudbjartsson, Daniel F.; Haahtela, Tari; Heckbert, Susan R.; Heederik, Dick; Heinrich, Joachim; Heliovaara, Markku; Henderson, John; Himes, Blanca E.; Hirose, Hiroshi; Hirschhorn, Joel N.; Hofman, Albert; Holt, Patrick; Hottenga, Jouke; Hudson, Thomas J.; Hui, Jennie; Imboden, Medea; Ivanov, Vladimir; Jaddoe, Vincent W. V.; James, Alan; Janson, Christer; Jarvelin, Marjo-Riitta; Jarvis, Deborah; Jones, Graham; Jonsdottir, Ingileif; Jousilahti, Pekka; Kabesch, Michael; Kahonen, Mika; Kantor, David B.; Karunas, Alexandra S.; Khusnutdinova, Elza; Koppelman, Gerard H.; Kozyrskyj, Anita L.; Kreiner, Eskil; Kubo, Michiaki; Kumar, Rajesh; Kumar, Ashish; Kuokkanen, Mikko; Lahousse, Lies; Laitinen, Tarja; Laprise, Catherine; Lathrop, Mark; Lau, Susanne; Lee, Young-Ae; Lehtimaki, Terho; Letort, Sebastien; Levin, Albert M.; Li, Guo; Liang, Liming; Loehr, Laura R.; London, Stephanie J.; Loth, Daan W.; Manichaikul, Ani; Marenholz, Ingo; Martinez, Fernando J.; Matheson, Melanie C.; Mathias, Rasika A.; Matsumoto, Kenji; Mbarek, Hamdi; McArdle, Wendy L.; Melbye, Mads; Melen, Erik; Meyers, Deborah; Michel, Sven; Mohamdi, Hamida; Musk, Arthur W.; Myers, Rachel A.; Nieuwenhuis, Maartje A. E.; Noguchi, Emiko; O'Connor, George T.; Ogorodova, Ludmila M.; Palmer, Cameron D.; Palotie, Aarno; Park, Julie E.; Pennell, Craig E.; Pershagen, Goran; Polonikov, Alexey; Postma, Dirkje S.; Probst-Hensch, Nicole; Puzyrev, Valery P.; Raby, Benjamin A.; Raitakari, Olli T.; Ramasamy, Adaikalavan; Rich, Stephen S.; Robertson, Colin F.; Romieu, Isabelle; Salam, Muhammad T.; Salomaa, Veikko; Schlunssen, Vivi; Scott, Robert; Selivanova, Polina A.; Sigsgaard, Torben; Simpson, Angela; Siroux, Valerie; Smith, Lewis J.; Solodilova, Maria; Standl, Marie; Stefansson, Kari; Strachan, David P.; Stricker, Bruno H.; Takahashi, Atsushi; Thompson, Philip J.; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Tiesler, Carla M. T.; Torgerson, Dara G.; Tsunoda, Tatsuhiko; Uitterlinden, Andre G.; van der Valk, Ralf J. P.; Vaysse, Amaury; Vedantam, Sailaja; von Berg, Andrea; von Mutius, Erika; Vonk, Judith M.; Waage, Johannes; Wareham, Nick J.; Weiss, Scott T.; White, Wendy B.; Wickman, Magnus; Widen, Elisabeth; Willemsen, Gonneke; Williams, L. Keoki; Wouters, Inge M.; Yang, James J.; Zhao, Jing Hua; Moffatt, Miriam F.; Ober, Carole; Nicolae, Dan L. 分享 收藏
No genetic association detected with mepolizumab efficacy in severe asthma Condreay, Lynn; Chiano, Mathias; Ortega, Hector; Buchan, Natalie; Harris, Elizabeth; Bleecker, Eugene R.; Thompson, Philip J.; Humbert, Marc; Gibson, Peter; Yancey, Steven; Ghosh, Soumitra 分享 收藏
Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology Ferreira, Manuel A.; Vonk, Judith M.; Baurecht, Hansjorg; Marenholz, Ingo; Tian, Chao; Hoffman, Joshua D.; Helmer, Quinta; Tillander, Annika; Ullemar, Vilhelmina; van Dongen, Jenny; Lu, Yi; Rueschendorf, Franz; Esparza-Gordillo, Jorge; Medway, Chris W.; Mountjoy, Edward; Burrows, Kimberley; Hummel, Oliver; Grosche, Sarah; Brumpton, Ben M.; Witte, John S.; Hottenga, Jouke-Jan; Willemsen, Gonneke; Zheng, Jie; Rodriguez, Elke; Hotze, Melanie; Franke, Andre; Revez, Joana A.; Beesley, Jonathan; Matheson, Melanie C.; Dharmage, Shyamali C.; Bain, Lisa M.; Fritsche, Lars G.; Gabrielsen, Maiken E.; Balliu, Brunilda; Nielsen, Jonas B.; Zhou, Wei; Hveem, Kristian; Langhammer, Arnulf; Holmen, Oddgeir L.; Loset, Mari; Abecasis, Goncalo R.; Willer, Cristen J.; Arnold, Andreas; Homuth, Georg; Schmidt, Carsten O.; Thompson, Philip J.; Martin, Nicholas G.; Duffy, David L.; Novak, Natalija; Schulz, Holger; Karrasch, Stefan; Gieger, Christian; Strauch, Konstantin; Melles, Ronald B.; Hinds, David A.; Huebner, Norbert; Weidinger, Stephan; Magnusson, Patrik K. E.; Jansen, Rick; Jorgenson, Eric; Lee, Young-Ae; Boomsma, Dorret I.; Almqvist, Catarina; Karlsson, Robert; Koppelman, Gerard H.; Paternoster, Lavinia 分享 收藏
Quantitative disease progression model of α-1 proteinase inhibitor therapy on computed tomography lung density in patients with α-1 antitrypsin deficiency Tortorici, Michael A.; Rogers, James A.; Vit, Oliver; Bexon, Martin; Sandhaus, Robert A.; Burdon, Jonathan; Chorostowska-Wynimko, Joanna; Thompson, Philip; Stocks, James; McElvaney, Noel G.; Chapman, Kenneth R.; Edelman, Jonathan M. 分享 收藏
Gene-based analysis of regulatory variants identifies 4 putative novel asthma risk genes related to nucleotide synthesis and signaling Ferreira, Manuel A. R.; Jansen, Rick; Willemsen, Gonneke; Penninx, Brenda; Bain, Lisa M.; Vicente, Cristina T.; Revez, Joana A.; Matheson, Melanie C.; Hui, Jennie; Tung, Joyce Y.; Baltic, Svetlana; Le Souef, Peter; Montgomery, Grant W.; Martin, Nicholas G.; Robertson, Colin F.; James, Alan; Thompson, Philip J.; Boomsma, Dorret I.; Hopper, John L.; Hinds, David A.; Werder, Rhiannon B.; Phipps, Simon 分享 收藏
Characteristics associated with clinical severity and inflammatory phenotype of naturally occurring virus-induced exacerbations of asthma in adults Bjerregaard, Asger; Laing, Ingrid A.; Poulsen, Nadia; Backer, Vibeke; Sverrild, Asger; Fally, Markus; Khoo, Siew-Kim; Barrett, Lucy; Baltic, Svetlana; Thompson, Philip J.; Chidlow, Glenys; Sikazwe, Chisha; Smith, David W.; Bochkov, Yury A.; Le Souef, Peter; Porsbjerg, Celeste 分享 收藏
Long-term efficacy and safety of α1 proteinase inhibitor treatment for emphysema caused by severe α1 antitrypsin deficiency: an open-label extension trial (RAPID-OLE) McElvaney, Noel G.; Burdon, Jonathan; Holmes, Mark; Glanville, Allan; Wark, Peter A. B.; Thompson, Philip J.; Hernandez, Paul; Chlumsky, Jan; Teschler, Helmut; Ficker, Joachim H.; Seersholm, Niels; Altraja, Alan; Makitaro, Riitta; Chorostowska-Wynimko, Joanna; Sanak, Marek; Stoicescu, Paul I.; Piitulainen, Eeva; Vit, Oliver; Wencker, Marion; Tortorici, Michael A.; Fries, Michael; Edelman, Jonathan M.; Chapman, Kenneth R. 分享 收藏
Signalling through the receptor for advanced glycation end products (RAGE) is increased in acute asthma and correlates with symptom severity Bjerregaard, Asger; Porsbjerg, Celeste; Barrett, Lucy; Laing, Ingrid; Khoo, Siew-Kim; Fally, Markus; Le Souef, Peter; Backer, Vibeke; Thompson, Philip; Baltic, Svetlana 分享 收藏
LSC Abstract - Investigating SOCS-mediated regulation of STAT signalling in idiopathic pulmonary fibrosis (IPF) Prele, Cecilia; Iosifidis, Thomas; McAnulty, Robin; Badrian, Bahareh; Jamieson, Sarra; Pearce, David; Ernst, Matthias; Thompson, Philip; Laurent, Geoffrey; Knight, Darryl; Mutsaers, Steven 分享 收藏
Identification of STOML2 as a putative novel asthma risk gene associated with IL6R Revez, J. A.; Matheson, M. C.; Hui, J.; Baltic, S.; James, A.; Upham, J. W.; Dharmage, S.; Thompson, P. J.; Martin, N. G.; Hopper, J. L.; Ferreira, M. A. R. 分享 收藏
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Meta-analysis identifies seven susceptibility loci involved in the atopic march Marenholz, Ingo; Esparza-Gordillo, Jorge; Rueschendorf, Franz; Bauerfeind, Anja; Strachan, David P.; Spycher, Ben D.; Baurecht, Hansjoerg; Margaritte-Jeannin, Patricia; Saaf, Annika; Kerkhof, Marjan; Ege, Markus; Baltic, Svetlana; Matheson, Melanie C.; Li, Jin; Michel, Sven; Ang, Wei Q.; McArdle, Wendy; Arnold, Andreas; Homuth, Georg; Demenais, Florence; Bouzigon, Emmanuelle; Soderhall, Cilla; Pershagen, Goran; de Jongste, Johan C.; Postma, Dirkje S.; Braun-Fahrlaender, Charlotte; Horak, Elisabeth; Ogorodova, Ludmila M.; Puzyrev, Valery P.; Bragina, Elena Yu; Hudson, Thomas J.; Morin, Charles; Duffy, David L.; Marks, Guy B.; Robertson, Colin F.; Montgomery, Grant W.; Musk, Bill; Thompson, Philip J.; Martin, Nicholas G.; James, Alan; Sleiman, Patrick; Toskala, Elina; Rodriguez, Elke; Foelster-Holst, Regina; Franke, Andre; Lieb, Wolfgang; Gieger, Christian; Heinzmann, Andrea; Rietschel, Ernst; Keil, Thomas; Cichon, Sven; Noethen, Markus M.; Pennell, Craig E.; Sly, Peter D.; Schmidt, Carsten O.; Matanovic, Anja; Schneider, Valentin; Heinig, Matthias; Huebner, Norbert; Holt, Patrick G.; Lau, Susanne; Kabesch, Michael; Weidinger, Stefan; Hakonarson, Hakon; Ferreira, Manuel A. R.; Laprise, Catherine; Freidin, Maxim B.; Genuneit, Jon; Koppelman, Gerard H.; Melen, Erik; Dizier, Marie-Helene; Henderson, A. John; Lee, Young Ae 分享 收藏
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