Elizabeth K. Speliotes - Publications, H-index & Citations

Elizabeth K. Speliotes

university of michigan

64H指数

189论文数

3.9W被引数

收录论文 79

发表时间

LYPLAL1 Rare Loss-of-Function Variants in Humans and Deletion in Human Hepatoma Cells Protect Against MASLD LYPLAL1 在人类中罕见的失活功能变异体以及在人肝癌细胞中的缺失可抵抗 MASLD

Journal of Lipid Research

IF4.1

2026-03-03

OAAI

Rawdat Hussain; Chinmay Raut; Ponnandy Prabhu; Akram Irshaid; Yash Hegde; Yue Chen; Asmita Pant; Antonino Oliveri; Xiaochao Wei; Lishi Yin; Tiffany L. Russell; Brian Halligan; Clay F. Semenkovich; Elizabeth K. Speliotes

Anthropometric Measures and Mortality Risk in Individuals With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Population-Based Cohort Study 人体测量指标与代谢功能障碍相关脂肪性肝病（MASLD）患者死亡风险：一项基于人群的队列研究

ALIMENTARY PHARMACOLOGY & THERAPEUTICS

IF6.7

2025-05-14

PREAI

Yeo, YH; Zhu, YX; Gao, JL; Liu, SH; Ni, WJ; Rui, FJ; Bai, X; Geng, N; Jin, R; Speliotes, EK; Wu, C; Shi, JP; Qi, XL; Chen, VL; Newsome, PN; Li, J

Functional interrogation of cellular Lp(a) uptake by genome-scale CRISPR screening 通过全基因组CRISPR筛选对细胞Lp(a)摄取的功能性探究

ATHEROSCLEROSIS

IF5.7

2025-04-01

OAAI

Khan, Taslima G.; Cunha, Juliana Bragazzi; Raut, Chinmay; Burroughs, Michael; Vyas, Hitarthi S.; Leix, Kyle; Goonewardena, Sascha N.; Smrcka, Alan V.; Speliotes, Elizabeth K.; Emmer, Brian T.

Genetic insight into the relationship between inflammatory bowel disease and Clostridioides difficile infection

MSPHERE

IF3.1

2024-11-21

OAAI

Cushing-Damm, Kelly C.; Chen, Yanhua; Du, Xiaomeng; Kuppa, Annapurna; Raut, Chinmay; Oliveri, Antonino; Chen, Vincent L.; Vanderwerff, Brett; Zawistowski, Matt; Rao, Krishna; Higgins, Peter; Speliotes, Elizabeth K.

PNPLA3 I148M Interacts With Environmental Triggers to Cause Human Disease PNPLA3 I148M与环境触发因素相互作用，导致人类疾病

LIVER INTERNATIONAL

IF5.2

2024-11-19

PREAI

Speliotes, Elizabeth K.; Schneider, Carolin Victoria

Genetic risk accentuates dietary effects on hepatic steatosis, inflammation and fibrosis in a population-based cohort 在基于人群的队列中，遗传风险加剧了饮食对肝脂肪变性，炎症和纤维化的影响

JOURNAL OF HEPATOLOGY

IF33

2024-09-01

OAAI

Chen, Vincent L.; Du, Xiaomeng; Oliveri, Antonino; Chen, Yanhua; Kuppa, Annapurna; Halligan, Brian D.; Province, Michael A.; Speliotes, Elizabeth K.

Human Genetic Study of Triglyceride to HDL-C Ratio Adjusted for BMI Identifies New Insulin Resistance-Associated Loci, Genes, Pathways, and Disease Subtypes

DIABETES

IF7.5

2024-06-14

PREAI

Oliveri, Antonino; Rebernick, Ryan; Speliotes, Elizabeth K.

Multiancestry Whole Genome Sequencing (WGS) Metaanalysis to Identify Loci Associated with Imaging-Measured Hepatic Steatosis

DIABETES

IF7.5

2024-06-14

PREAI

Allred, Nicholette; Raut, Chinmay; Chen, Yanhua; Oliveri, Antonino; O'Connell, Jeffrey; Ryan, Kathleen; Rotter, Jerome I.; Rich, Stephen S.; Hakim, Aaron; Peyser, Patricia; Bielak, Lawrence F.; Liu, Ching-Ti; Terry, James G.; Fornage, Myriam; Wagenknecht, Lynne E.; Speliotes, Elizabeth K.

PNPLA3 Risk Allele Association With ALT Response to Semaglutide Treatment PNPLA3风险等位基因与对somaglutide治疗的ALT反应的关联

GASTROENTEROLOGY

IF25.1

2024-03-01

OAAI

Urias, Esteban; Tedesco, Nicholas R.; Oliveri, Antonino; Raut, Chinmay; Speliotes, Elizabeth K.; Chen, Vincent L.

Comprehensive genetic study of the insulin resistance marker TG:HDL-C in the UK Biobank 英国生物银行对胰岛素抵抗标志物TG: hdl-c的综合遗传研究

NATURE GENETICS

IF31.8

2024-01-10

OAAI

Oliveri, Antonino; Rebernick, Ryan J.; Kuppa, Annapurna; Pant, Asmita; Chen, Yanhua; Du, Xiaomeng; Cushing, Kelly C.; Bell, Hannah N.; Raut, Chinmay; Prabhu, Ponnandy; Chen, Vincent L.; Halligan, Brian D.; Speliotes, Elizabeth K.

A common variant that alters SUN1 degradation associates with hepatic steatosis and metabolic traits in multiple cohorts

JOURNAL OF HEPATOLOGY

IF33

2023-11-01

OAAI

Upadhyay, Kapil K.; Du, Xiaomeng; Chen, Yanhua; Buscher, Brandon; Chen, Vincent L.; Oliveri, Antonino; Zhao, Raymond; Speliotes, Elizabeth K.; Brady, Graham F.

Genome-wide association meta-analysis identifies 17 loci associated with nonalcoholic fatty liver disease 全基因组关联荟萃分析确定了17个与非酒精性脂肪性肝病相关的基因座

NATURE GENETICS

IF31.8

2023-09-14

OAAI

Chen, Yanhua; Du, Xiaomeng; Kuppa, Annapurna; Feitosa, Mary F.; Bielak, Lawrence F.; O'Connell, Jeffrey R.; Musani, Solomon K.; Guo, Xiuqing; Kahali, Bratati; Chen, Vincent L.; Smith, Albert V.; Ryan, Kathleen A.; Eirksdottir, Gudny; Allison, Matthew A.; Bowden, Donald W.; Budoff, Matthew J.; Carr, John Jeffrey; Chen, Yii-Der I.; Taylor, Kent D.; Oliveri, Antonino; Correa, Adolfo; Crudup, Breland F.; Kardia, Sharon L. R.; Mosley, Thomas H.; Norris, Jill M.; Terry, James G.; Rotter, Jerome I.; Wagenknecht, Lynne E.; Halligan, Brian D.; Young, Kendra A.; Hokanson, John E.; Washko, George R.; Gudnason, Vilmundur; Province, Michael A.; Peyser, Patricia A.; Palmer, Nicholette D.; Speliotes, Elizabeth K.

Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology (vol 12, 816, 2021)

NATURE COMMUNICATIONS

IF15.7

2023-06-08

OAAI

Chen, Vincent L.; Du, Xiaomeng; Chen, Yanhua; Kuppa, Annapurna; Handelman, Samuel K.; Vohnoutka, Rishel B.; Peyser, Patricia A.; Palmer, Nicholette D.; Bielak, Lawrence F.; Halligan, Brian; Speliotes, Elizabeth K.

PNPLA3 eGenotype and Diabetes Identify Patients With Nonalcoholic Fatty Liver Disease at High Risk of Incident Cirrhosis PNPLA3 e基因型和糖尿病确定非酒精性脂肪性肝病患者发生肝硬化的高风险

GASTROENTEROLOGY

IF25.1

2023-05-01

PREAI

Chen, Vincent L.; Oliveri, Antonino; Miller, Matthew J.; Wijarnpreecha, Karn; Du, Xiaomeng; Chen, Yanhua; Cushing, Kelly C.; Lok, Anna S.; Speliotes, Elizabeth K.

Non-Alcoholic Fatty Liver Disease and Vitamin D in the UK Biobank: A Two-Sample Bidirectional Mendelian Randomisation Study

NUTRIENTS

IF5

2023-03-16

OAAI

Zhang, Zixuan; Burrows, Kimberley; Fuller, Harriett; Speliotes, Elizabeth K.; Abeysekera, Kushala W. M.; Thorne, James L.; Lewis, Sarah J.; Zulyniak, Michael A.; Moore, J. Bernadette

Knockout of murine Lyplal1 confers sex-specific protection against diet-induced obesity

JOURNAL OF MOLECULAR ENDOCRINOLOGY

IF3.8

2023-02-07

OAAI

Vohnoutka, Rishel B.; Kuppa, Annapurna; Hegde, Yash; Chen, Yue; Pant, Asmita; Tohme, Maurice E.; Choi, Eun-Young (Karen); McCarty, Sean M.; Bagchi, Devika P.; Du, Xiaomeng; Chen, Yanhua; Chen, Vincent L.; Mori, Hiroyuki; Bielak, Lawrence F.; Maguire, Lillias H.; Handelman, Samuel K.; Sexton, Jonathan Z.; Saunders, Thomas L.; Halligan, Brian D.; Speliotes, Elizabeth K.

ALDH1A1 Expression Is Enriched in Early-Onset Colorectal Cancers

GASTROENTEROLOGY

IF25.1

2022-12-01

OAAI

Venugopal, Anand; Koi, Minoru; Choi, Chan; Kim, Hyeong-Rok; Speliotes, Elizabeth K.; Carethers, John M.

Population-based meta-analysis and gene-set enrichment identifies FXR/RXR pathway as common to fatty liver disease and serum lipids

HEPATOLOGY COMMUNICATIONS

IF4.6

2022-09-13

OAAI

Handelman, Samuel K.; Puentes, Yindra M.; Kuppa, Annapurna; Chen, Yanhua; Du, Xiaomeng; Feitosa, Mary F.; Palmer, Nicholette D.; Speliotes, Elizabeth K.

Polygenic Risk Prediction in Diverticulitis

ANNALS OF SURGERY

IF6.4

2022-07-25

PREAI

De Roo, Ana C.; Chen, Yanhua; Du, Xiaomeng; Handelman, Samuel; Byrnes, Mary; Regenbogen, Scott E.; Speliotes, Elizabeth K.; Maguire, Lillias H.

Hepatic decompensation is accelerated in patients with cirrhosis and alpha-1 antitrypsin Pi*MZ genotype

JHEP REPORTS

IF7.5

2022-06-01

OAAI

Chen, Vincent L.; Burkholder, Daniel A.; Moran, Isabel J.; V. DiBattista, Jacob; Miller, Matthew J.; Chen, Yanhua; Du, Xiaomeng; Oliveri, Antonino; Cushing, Kelly C.; Lok, Anna S.; Speliotes, Elizabeth K.

研究方向