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J

John C. Williams

city of hope national medical center

38H指数
189论文数
6.1K被引数
收录论文 66
发表时间
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Generation of mixed-valency, modular multispecific antibodies using disulfide-linked Fc–FcγR complexes利用二硫键连接的Fc–FcγR复合物生成混合价态、模块化多特异性抗体
errNature Communications
IF15.7
err2026-04-28
err0
errOAAI
errMiso Park; Kevin Ly; Bea Parcutela; Hyeran Choi; Carmina Ladra; Asaul Gonzalez; Yead Jewel; Hyunjun Kang; Melissa Valerio; Aparna Krishnan; Timothy W. Synold; Le Xuan Truong Nguyen; Guido Marcucci; John C. Williams
err分享
err收藏
Comment: Leber's Hereditary Optic Neuropathy in a Nonagenarian评论：Leber's Hereditary Optic Neuropathy在一位九旬老人中
errJOURNAL OF NEURO-OPHTHALMOLOGY
IF2
err2025-12-01
err0
PREAI
errWilliams, John J.; Swan, Robert T.; Naum, Allayna M.; Mejico, Luis J.
err分享
err收藏
MicroRNA-142 improves IL1RAP CAR-T cell activity in acute myeloid leukemiaMicroRNA-142改善急性髓系白血病IL1RAP car-t细胞活性
errJournal of Hematology & Oncology
IF40.4
err2025-11-17
err0
errOAAI
errKaito Harada; Dandan Zhao; Miso Park; Fang Chen; Yongfang Xu; Yi Zhang; Yile Zhou; Bea Parcutela; Yead Jewel; Ashlie Munoz; Idoroenyi Amanam; Le Xuan Truong Nguyen; Jianjun Chen; Lucy Ghoda; Stephen J. Forman; John C. Williams; Bin Zhang; Guido Marcucci
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err收藏
Development of EGFR/IL13Ra2 bispecific CAR T cells to overcome heterogeneous glioblastomaEGFR/IL13Ra2双特异性CAR T细胞的开发以克服异质性胶质母细胞瘤
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errDu, Kaixin; Villasenor, Yolanda; Machuca, Robert; Trac, Candi; Park, Miso; Ma, Eric; Masia, Christian; Rothe, Michael; Jewel, Yead; Williams, John; Brown, Christine
err分享
err收藏
Single-residue engineering of lambda (λ) antibody light chains reduces conformational flexibility and enhances thermal stability单残基工程改造λ抗体轻链可降低构象灵活性并提高热稳定性
errComputational and Structural Biotechnology Journal
IF4.1
err2025-10-24
err0
errOAAI
errYead Jewel; Tynan Young; Miso Park; Kevin Ly; Asaul Gonzalez; T Conn Mallett; John C. Williams
err分享
err收藏
Development of an ultrahigh affinity, trimeric ACE2 biologic as a universal SARS-CoV-2 antagonist一种具有超高效力、三聚体ACE2生物制剂的开发，作为通用SARS-CoV-2拮抗剂
errCommunications Biology
IF5.1
err2025-10-06
err0
errOAAI
errJuliet Gonzales; Tynan Young; Hyeran Choi; Miso Park; Yead Jewel; Chengcheng Fan; Rahul Purohit; Pamela J. Bjorkman; John C. Williams
err分享
err收藏
Genetic protection from type 1 diabetes resulting from accelerated insulin mRNA decay由加速的胰岛素mRNA降解引起的1型糖尿病的遗传保护
errCELL
IF42.5
err2025-05-01
err1
errOAAI
errvan Tienhoven, Rene; O'Meally, Denis; Scott, Tristan A.; Morris, Kevin V.; Williams, John C.; Kaddis, John S.; Zaldumbide, Arnaud; Roep, Bart O.
err分享
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Utility of binding protein fusions to immunoglobulin heavy chain constant regions from mammalian and avian species
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2025-02-01
err0
errOAAI
errZhu, Ningyu; Smallwood, Philip M.; Williams, John; Wang, Yanshu; Nathans, Jeremy H.
err分享
err收藏
IL1RAP-specific T cell engager depletes acute myeloid leukemia stem cellsIL1RAP-specific T细胞衔接器耗尽急性髓性白血病干细胞
errJOURNAL OF HEMATOLOGY & ONCOLOGY
IF40.4
err2024-08-14
err2
errOAAI
errZhang, Yi; Park, Miso; Ghoda, Lucy Y.; Zhao, Dandan; Valerio, Melissa; Nafie, Ebtesam; Gonzalez, Asaul; Ly, Kevin; Parcutela, Bea; Choi, Hyeran; Gong, Xubo; Chen, Fang; Harada, Kaito; Chen, Zhenhua; Nguyen, Le Xuan Truong; Pichiorri, Flavia; Chen, Jianjun; Song, Joo; Forman, Stephen J.; Amanam, Idoroenyi; Zhang, Bin; Jin, Jie; Williams, John C.; Marcucci, Guido
err分享
err收藏
Utility of protein-protein binding surfaces composed of anti-parallel alpha-helices and beta-sheets selected by phage display
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-05-01
err0
errOAAI
errZhu, Ningyu; Smallwood, Philip M.; Rattner, Amir; Chang, Tao-Hsin; Williams, John; Wang, Yanshu; Nathans, Jeremy
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err收藏
Induction of islet autoimmunity to defective ribosomal product of the insulin gene as neoantigen after anti-cancer immunotherapy leading to autoimmune diabetes在导致自身免疫性糖尿病的抗癌免疫疗法后，胰岛自身免疫对胰岛素基因缺陷核糖体产物作为新抗原的诱导
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2024-03-26
err1
errOAAI
errvan Tienhoven, Rene; Jansen, Diahann T. S. L.; Park, Miso; Williams, John C.; Larkin, James; Quezada, Sergio A.; Roep, Bart O.
err分享
err收藏
XTX101, a tumor-activated, Fc-enhanced anti-CTLA-4 monoclonal antibody, demonstrates tumor-growth inhibition and tumor-selective pharmacodynamics in mouse models of cancerXTX101是一种肿瘤激活的Fc增强anti-CTLA-4单克隆抗体，在小鼠癌症模型中表现出肿瘤生长抑制和肿瘤选择性药效学
errJOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
err2023-12-12
err3
errOAAI
errJenkins, Kurt A.; Park, Miso; Pederzoli-Ribeil, Magali; Eskiocak, Ugur; Johnson, Parker; Guzman, Wilson; Mclaughlin, Megan; Moore-Lai, Deborah; O'Toole, Caitlin; Liu, Zhen; Nicholson, Benjamin; Flesch, Veronica; Qiu, Huawei; Clackson, Tim; O'Hagan, Ronan C.; Rodeck, Ulrich; Karow, Margaret; O'Neil, Jennifer; Williams, John C.
err分享
err收藏
Mass Spectrometric Detection of Formaldehyde-Crosslinked PBMC Proteins in Cell-Free DNA Blood Collection Tubes
errMOLECULES
IF4.6
err2023-11-30
err1
errOAAI
errRoth, Daniel; Molina-Franky, Jessica; Williams, John C.; Kalkum, Markus
err分享
err收藏
Using quantitative single molecule localization microscopy to optimize multivalent HER2-targeting ligands
errFRONTIERS IN MEDICINE
IF3
err2023-04-17
err1
errOAAI
errWakefield, Devin L.; Golfetto, Ottavia; Jorand, Raphael; Biswas, Sunetra; Meyer, Kassondra; Avery, Kendra N.; Zer, Cindy; Cacao, Eliedonna E.; Tobin, Steven J.; Talisman, Ian J.; Williams, John C.; Jovanovic-Talisman, Tijana
err分享
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Normal light response, photoreceptor integrity, and rhodopsin dephosphorylation in mice lacking both protein phosphatases with EF hands (PPEF-1 and PPEF-2)
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err28
errOAAI
errRamulu, P; Kennedy, M; Xiong, WH; Williams, J; Cowan, M; Blesh, D; Yau, KW; Hurley, JB; Nathans, J
err分享
err收藏
Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes
errIMMUNITY
IF26.3
err2022-12-01
err25
errOAAI
errFan, Chengcheng; Cohen, Alexander A.; Park, Miso; Hung, Alfur Fu-Hsin; Keeffe, Jennifer R.; Gnanapragasam, Priyanthi N. P.; Lee, Yu E.; Gao, Han; Kakutani, Leesa M.; Wu, Ziyan; Kleanthous, Harry; Malecek, Kathryn E.; Williams, John C.; Bjorkman, Pamela J.
err分享
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Magic-angle-spinning NMR structure of the kinesin-1 motor domain assembled with microtubules reveals the elusive neck linker orientation
errNATURE COMMUNICATIONS
IF15.7
err2022-11-10
err8
errOAAI
errZhang, Chunting; Guo, Changmiao; Russell, Ryan W.; Quinn, Caitlin M.; Li, Mingyue; Williams, John C.; Gronenborn, Angela M.; Polenova, Tatyana
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err收藏
Antibody-based redirection of meditope-CAR T cells selectively kill antigen bearing tumor cells
errCANCER RESEARCH
IF16.6
err2020-08-15
err0
PREAI
errKuo, Yi-Chiu; King, Jeremy D.; Kuo, Cheng-Fu; Kenyon, Victor; Park, Miso; Chang, Wen-Chung; Stern, Lawrence; Brown, Christine E.; Williams, John C.
err分享
err收藏
Comprehensive analysis of a mouse model of spontaneous uveoretinitis using single-cell RNA sequencing
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2019-12-16
err43
errOAAI
errHeng, Jacob S.; Hackett, Sean F.; Stein-O'Brien, Genevieve L.; Winer, Briana L.; Williams, John; Goff, Loyal A.; Nathans, Jeremy
err分享
err收藏
Conformational Flexibility of p150Glued (1-191) Subunit of Dynactin Assembled with Microtubules
errBIOPHYSICAL JOURNAL
IF3.1
err2019-09-01
err5
errOAAI
errGuo, Changmiao; Williams, John C.; Polenova, Tatyana
err分享
err收藏

研究方向

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合作学者
合作期刊
H
Hideo Yagita∥
H 指数: 144 · 论文数: 1.3K
M
Makoto M. Taketo
H 指数: 128 · 论文数: 688
J
James Larkin
H 指数: 128 · 论文数: 1.3K
S
Stephen J. Forman
H 指数: 127 · 论文数: 1.8K
A
Angela M. Gronenborn
H 指数: 119 · 论文数: 798
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