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S

Sibylle Madlener

department of pediatrics
H指数:30
被引数:3,531

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Nanopore-based liquid biopsy analysis enables preoperative tumor classification in pediatric brain tumors

基于纳米孔的液体活检分析能够实现儿童脑肿瘤的术前肿瘤分类

Acta Neuropathologica Communications
IF5.7
2026-08-010
OA
Natalia Stepien; Dagmar Al Tukmachi; Maciej Balura; Petra Pokorna; Katharina Bruckner; Anna Laemmerer; Julia Freund; Sarah Machreich; Bernhard Robl; Amedeo A. Azizi; Andreas Peyrl; Lisa Mayr; Jaroslav Sterba; Bernhard Hennebichler; Christine Haberler; Leonhard Müllauer; Gregor Kasprian; Christian Dorfer; Daniel Senfter; Sibylle Madlener; Johannes Gojo
Co-targeting CDK4/6 and MEK reverses mesenchymal transition in therapy-refractory BRAF-altered pediatric high-grade glioma

联合靶向CDK4/6和MEK逆转治疗耐药型BRAF突变型儿童高级别胶质瘤的间充质转化

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
IF12.8
2026-05-160
OAAI
Lisa Mayr; Leah Mager; Lisa Gabler-Pamer; Dominik Kirchhofer; Julia Freund; Kallen Schwark; Benison Lau; Sarah Machreich; Daniel Senfter; Mia Neumüller; Alexandra Lang; Sibylle Madlener; Anna Laemmerer; Katharina Bruckner; Carola N. Jaunecker; Bernhard Robl; Romina Walter; Julia Schueler; Andreas Peyrl; Amedeo A. Azizi; Christian Dorfer; Karl Roessler; Sabine Spiegl-Kreinecker; Christine Haberler; Aniello Federico; Apurva Gopisetty; Gudrun Schleiermacher; Stefan M. Pfister; Birgit Geoerger; Louis Chesler; Gilles Vassal; Marcel Kool; Leonhard Müllauer; Carl Koschmann; Walter Berger; Johannes Gojo; Daniela Lötsch
Tumor-suppressive role of miR-216b impacts cell cycle regulation in high-grade glioma

miR-216b的肿瘤抑制角色影响高级别胶质瘤中的细胞周期调控

Acta Neuropathologica Communications
IF5.7
2026-04-060
OAAI
Alexandra Lang; Sabine Buerger; Leah Mager; Lea Erjavc; Barbara Kiesel; Sibylle Madlener; Carola Nadine Jaunecker; Linda Pacher; Finn Christopher Robert; Leonie Krausgruber; Andrezza Nascimento; Sarah Machreich; Gerda Ricken; Lisa Gabler-Pamer; Anna Laemmerer; Sabine Spiegl-Kreinecker; Matthias Hackl; Marianne Pultar; Johannes Reisecker; Katharina Bruckner; Barbara Neudert; Leonhard Muellauer; Dominik Kirchhofer; Mario Mischkulnig; Anna Sophie Berghoff; Adelheid Woehrer; Daniel Senfter; Karl Roessler; Thomas Roetzer-Pejrimovsky; Walter Berger; Johannes Andreas Hainfellner; Romana Hoeftberger; Georg Widhalm; Friedrich Erhart; Daniela Lötsch-Gojo
M-PACT leverages cell-free DNA methylomes to achieve robust classification of pediatric brain tumors
Nature Cancer
IF28.5
2026-02-014
PRE
Smith, Kyle S.; Fischer, Tom T.; Han, Katie; Kostecka, Anna; Lin, Hong; Senfter, Daniel; Soliman, Taha; Stepien, Natalia; Volz, Stefanie; Schwarz, Nathalie; Wedig, Tatjana; Madlener, Sibylle; Haberler, Christine; Dhanda, Sandeep K.; Upadhyaya, Santhosh A.; Blackburn, Patrick R.; Schmook, Maria T.; De Bont, Judith; Haapasalo, Hannu; Dargvainiene, Justina; Leypoldt, Frank; Pfister, Stefan M.; Hulleman, Esther; Orr, Brent A.; Gajjar, Amar; Robinson, Giles W.; Haapasalo, Joonas; Nordfors, Kristiina; Gojo, Johannes; Pajtler, Kristian W.; Maass, Kendra K.; Northcott, Paul A.
Robust classification of pediatric brain tumors from cell-free DNA methylomes

基于游离细胞DNA甲基组的儿童脑肿瘤鲁棒性分类

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Smith, Kyle; Fischer, Tom; Han, Katie; Kostecka, Anna; Lin, Hong; Senfter, Daniel; Stepien, Natalia; Volz, Stefanie; Schwarz, Nathalie; Wedig, Tatjana; Madlener, Sibylle; Haberler, Christine; Dhanda, Sandeep; Upadhyaya, Santhosh; Schmook, Maria; De Bont, Judith; Haapasalo, Hannu; Dargvainiene, Justina; Leypoldt, Frank; Pfister, Stefan; Hulleman, Esther; Gajjar, Amar; Robinson, Giles; Haapasalo, Joonas; Nordfors, Kristiina; Gojo, Johannes; Maass, Kendra; Pajtler, Kristian; Northcott, Paul
Cellular hierarchies of embryonal tumors with multilayered rosettes are shaped by oncogenic microRNAs and receptor-ligand interactions

胚胎性多分层菊形团肿瘤的细胞层次结构由致癌microRNAs和受体-配体相互作用塑造。

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Gabler-Pamer, Lisa; Beck, Alexander; Cruzeiro, Gustavo Alencastro Veiga; Lambo, Sander; Shaw, Mckenzie L.; Hack, Olivia A.; Nascimento, Andrezza; Madlener, Sibylle; Lotsch, Daniela; Slavc, Irene; Dorfer, Christian; Haberler, Christine; Baird, Lissa; Chi, Susan N.; Alexandrescu, Sanda; Gojo, Johannes; Marcel, Kool; Hovestadt, Volker; Filbin, Mariella G.
UNCOVERING THERAPEUTIC VULNERABILITIES IN PEDIATRIC BCOR/L1-DRIVEN CNS TUMORS THROUGH MULTI-OMICS PROFILING

通过多组学分析揭示儿科BCOR/L1驱动的CNS肿瘤的治疗易感性

NEURO-ONCOLOGY
IF13.4
2025-10-010
OAAI
Lotsch-Gojo, D.; Gabler-Pamer, L.; Bruckner, K.; Kirchhofer, D.; LaBelle, J.; Beck, A.; Wang, S.; Al Tukmachi, D.; Quack, J.; Madlener, S.; Senfter, D.; Federico, A.; Dorfer, C.; Eder, T.; Grebien, F.; Tauziede-Espariat, A.; Pahnke, J.; Bunt, J.; Hovestadt, V; Schueler, J.; Haberler, C.; Filbin, M. G.; Kool, M.; Berger, W.; Gojo, J.
Cellular hierarchies of embryonal tumors with multilayered rosettes are shaped by oncogenic microRNAs and receptor-ligand interactions

胚胎性多层层状-rosettes肿瘤的细胞层次结构由致癌microRNAs和受体-配体相互作用塑造。

NATURE CANCER
IF28.5
2025-05-260
OA
Beck, Alexander; Gabler-Pamer, Lisa; Alencastro Veiga Cruzeiro, Gustavo; Lambo, Sander; Englinger, Bernhard; Shaw, McKenzie L.; Hack, Olivia A.; Liu, Ilon; Haase, Rebecca D.; de Biagi Jr, Carlos A. O.; Baumgartner, Alicia; Nascimento Silva, Andrezza Do; Klenner, Marbod; Freidel, Pia S.; Herms, Jochen; von Baumgarten, Louisa; Tonn, Joerg C.; Thon, Niklas; Bruckner, Katharina; Madlener, Sibylle; Mayr, Lisa; Senfter, Daniel; Peyrl, Andreas; Slavc, Irene; Loetsch, Daniela; Dorfer, Christian; Geyregger, Rene; Amberg, Nicole; Haberler, Christine; Mack, Norman; Schwalm, Benjamin; Pfister, Stefan M.; Korshunov, Andrey; Baird, Lissa C.; Yang, Edward; Chi, Susan N.; Alexandrescu, Sanda; Gojo, Johannes; Kool, Marcel; Hovestadt, Volker; Filbin, Mariella G.
Detection of H3F3A K27M or BRAF V600E in liquid biopsies of brain tumor patients as diagnostic and monitoring biomarker: impact of tumor localization and sampling method

脑肿瘤患者液体活检中H3F3A K27M或BRAF V600E的检测作为诊断和监测生物标志物：肿瘤定位和采样方法的影响

ACTA NEUROPATHOLOGICA
IF9.3
2025-01-030
OA
Madlener, S; Stepien, N; Senfter, D; Mayr, L; Laemmerer, A; Hedrich, C; Baumgartner, A; Lötsch-Gojo, D; Sterba, J; Pokorna, P; Kiesel, B; Widhalm, G; Eckert, F; Preusser, M; Rössler, K; Azizi, A; Peyrl, A; Czech, T; Haberler, C; Slavc, I; Kasprian, G; Dorfer, C; Furtner, J; Gojo, J
Real-World Performance of Integrative Clinical Genomics in Pediatric Precision Oncology

综合临床基因组学在儿科精准肿瘤学中的真实表现

LABORATORY INVESTIGATION
IF4.2
2024-12-010
OAAI
Pokorna, Petra; Palova, Hana; Adamcova, Sona; Jugas, Robin; Al Tukmachi, Dagmar; Kyr, Michal; Knoflickova, Dana; Kozelkova, Katerina; Bystry, Vojtech; Mejstrikova, Sona; Merta, Tomas; Trachtova, Karolina; Podlipna, Eliska; Mudry, Peter; Pavelka, Zdenek; Bajciova, Viera; Tinka, Pavel; Jarosova, Marie; Ivkovic, Tina Catela; Madlener, Sibylle; Pal, Karol; Stepien, Natalia; Mayr, Lisa; Tichy, Boris; Drabova, Klara; Jezova, Marta; Kozakova, Sarka; Vanackova, Jitka; Radova, Lenka; Steininger, Karin; Haberler, Christine; Gojo, Johannes; Sterba, Jaroslav; Slaby, Ondrej
Alternative lengthening of telomere-based immortalization renders H3G34R-mutant diffuse hemispheric glioma hypersensitive to PARP inhibitor combination regimens
NEURO-ONCOLOGY
IF13.4
2024-11-180
PRE
Laemmerer, Anna; Lehmann, Christian; Mayr, Lisa; Bruckner, Katharina; Gabler, Lisa; Senfter, Daniel; Meyer, Philipp; Balber, Theresa; Pirker, Christine; Jaunecker, Carola N.; Kirchhofer, Dominik; Vician, Petra; Griesser, Michelle; Spiegl-Kreinecker, Sabine; Schmook, Maria T.; Traub-Weidinger, Tatjana; Kuess, Peter; Eckert, Franziska; Federico, Aniello; Madlener, Sibylle; Stepien, Natalia; Robl, Bernhard; Baumgartner, Alicia; Hainfellner, Johannes A.; Dieckmann, Karin; Dorfer, Christian; Roessler, Karl; Corsini, Nina S.; Holzmann, Klaus; Schmidt, Wolfgang M.; Peyrl, Andreas; Azizi, Amedeo A.; Haberler, Christine; Beck, Alexander; Pfister, Stefan M.; Schueler, Julia; Loetsch-Gojo, Daniela; Knoblich, Juergen A.; Berger, Walter; Gojo, Johannes
THE MIRNA 216B-5P ACTS AS A PROMISING TUMOR-SUPPRESSOR BY MANIPULATING CELL CYCLE PROGRESSION IN HIGH-GRADE GLIOMA CELLS
NEURO-ONCOLOGY
IF13.4
2024-10-170
PRE
Lang, A.; Buerger, S.; Mager, L.; Kiesel, B.; Madlener, S.; Ricken, G.; Laemmerer, A.; Spiegl-Kreinecker, S.; Hackl, M.; Pultar, M.; Reisecker, J.; Kirchhofer, D.; Mischkulnig, M.; Berghoff, A. S.; Woehrer, A.; Roessler, K.; Roetzer-Pejrimovsky, T.; Berger, W.; Jaunecker, C. N.; Hainfellner, J. A.; Hoeftberger, R.; Widhalm, G.; Erhart, F.; Loetsch-Gojo, D.
ROBUST CELL-FREE DNA METHYLATION-BASED CLASSIFICATION OF PEDIATRIC BRAIN TUMOR LIQUID BIOPSIES
NEURO-ONCOLOGY
IF13.4
2024-06-180
OAAI
Smith, Kyle S.; Fischer, Tom T.; Lin, Hong; Senfter, Daniel; Wedig, Tatjana; Schwarz, Nathalie; Stepien, Natalia; Madlener, Sibylle; Haberler, Christine; Hulleman, Esther; Atkinson, Natasha; Dhanda, Sandeep K.; Pfister, Stefan; Upadhyaya, Santhosh; Gajjar, Amar; Robinson, Giles W.; Haapasalo, Joonas; Haapasalo, Hannu; Nordfors, Kristiina; Gojo, Johannes; Maass, Kendra K.; Pajtler, Kristian W.; Northcott, Paul A.

研究方向

暂未获取到该数据
J
Johannes Gojo
H 指数:30论文数:301被引数:7,087
C
Christine Haberler
H 指数:50论文数:324被引数:1.6万
D
Daniel Senfter
H 指数:12论文数:56被引数:656
C
Christian Dorfer
H 指数:33论文数:287被引数:4,447
L
Lisa Mayr
H 指数:19论文数:108被引数:4,208
N
Natalia Stepien
H 指数:9论文数:49被引数:275
A
Andreas Peyrl
H 指数:29论文数:175被引数:3,450
D
Daniela Lötsch-Gojo
H 指数:9论文数:102被引数:230
I
Irene Slavc
H 指数:44论文数:310被引数:1.1万
A
Amedeo A. Azizi
H 指数:32论文数:244被引数:4,396