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Thiyagaraj Mayuranathan

department of hematology
H指数:11
被引数:1,110

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Preclinical development of lentiviral vector gene therapy for Diamond-Blackfan anemia syndrome

lentiviral vector gene therapy for Diamond-Blackfan anemia syndrome的preclinical development

Molecular Therapy
IF12
2024-12-120
OA
Senthil Velan Bhoopalan; Thiyagaraj Mayuranathan; Nana Liu; Kalin Mayberry; Yu Yao; Jingjing Zhang; Jean-Yves Métais; Koon-Kiu Yan; Robert E. Throm; Steven R. Ellis; Yan Ju; Lei Han; Shruthi Suryaprakash; Lance E. Palmer; Sheng Zhou; Jiyang Yu; Yong Cheng; Jonathan S. Yen; Stephen Gottschalk; Mitchell J. Weiss
Development and IND-enabling studies of a novel Cas9 genome-edited autologous CD34+cell therapy to induce fetal hemoglobin for sickle cell disease

新型Cas9基因组编辑的自体CD34细胞疗法诱导胎儿血红蛋白治疗镰状细胞病的开发和IND支持研究

MOLECULAR THERAPY
IF12
2024-10-010
OAAI
Katta, Varun; O'Keefe, Kiera; Li, Yichao; Mayuranathan, Thiyagaraj; Lazzarotto, Cicera R.; Wood, Rachael K.; Levine, Rachel M.; Powers, Alicia; Mayberry, Kalin; Manquen, Garret; Yao, Yu; Zhang, Jingjing; Jang, Yoonjeong; Nimmagadda, Nikitha; Dempsey, Erin A.; Lee, GaHyun; Uchida, Naoya; Cheng, Yong; Fazio, Frank; Lockey, Tim; Meagher, Mike; Sharma, Akshay; Tisdale, John F.; Zhou, Sheng; Yen, Jonathan S.; Weiss, Mitchell J.; Tsai, Shengdar Q.
Potent and uniform fetal hemoglobin induction via base editing
NATURE GENETICS
IF31.8
2023-07-0325
OAAI
Mayuranathan, Thiyagaraj; Newby, Gregory A.; Feng, Ruopeng; Yao, Yu; Mayberry, Kalin D.; Lazzarotto, Cicera R.; Li, Yichao; Levine, Rachel M.; Nimmagadda, Nikitha; Dempsey, Erin; Kang, Guolian; Porter, Shaina N.; Doerfler, Phillip A.; Zhang, Jingjing; Jang, Yoonjeong; Chen, Jingjing; Bell, Henry W.; Crossley, Merlin; Bhoopalan, Senthil Velan; Sharma, Akshay; Tisdale, John F.; Pruett-Miller, Shondra M.; Cheng, Yong; Tsai, Shengdar Q.; Liu, David R.; Weiss, Mitchell J.; Yen, Jonathan S.
Ex vivo prime editing of patient haematopoietic stem cells rescues sickle-cell disease phenotypes after engraftment in mice
NATURE BIOMEDICAL ENGINEERING
IF26.6
2023-04-1756
OAAI
Everette, Kelcee A.; Newby, Gregory A.; Levine, Rachel M.; Mayberry, Kalin; Jang, Yoonjeong; Mayuranathan, Thiyagaraj; Nimmagadda, Nikitha; Dempsey, Erin; Li, Yichao; Bhoopalan, Senthil Velan; Liu, Xiong; Davis, Jessie R.; Nelson, Andrew T.; Chen, Peter J.; Sousa, Alexander A.; Cheng, Yong; Tisdale, John F.; Weiss, Mitchell J.; Yen, Jonathan S.; Liu, David R.
Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells

双重功能NFI因子控制成人红系细胞中的胎儿血红蛋白沉默

NATURE GENETICS
IF31.8
2022-05-2619
OAAI
Qin, Kunhua; Huang, Peng; Feng, Ruopeng; Keller, Cheryl A.; Peslak, Scott A.; Khandros, Eugene; Saari, Megan S.; Lan, Xianjiang; Mayuranathan, Thiyagaraj; Doerfler, Phillip A.; Abdulmalik, Osheiza; Giardine, Belinda; Chou, Stella T.; Shi, Junwei; Hardison, Ross C.; Weiss, Mitchell J.; Blobel, Gerd A.
ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression

ZNF410独特地激活NuRD组分CHD4以沉默胎儿血红蛋白表达

MOLECULAR CELL
IF16.6
2021-01-0149
OAAI
Lan, Xianjiang; Ren, Ren; Feng, Ruopeng; Ly, Lana C.; Lan, Yemin; Zhang, Zhe; Aboreden, Nicholas; Qin, Kunhua; Horton, John R.; Grevet, Jeremy D.; Mayuranathan, Thiyagaraj; Abdulmalik, Osheiza; Keller, Cheryl A.; Giardine, Belinda; Hardison, Ross C.; Crossley, Merlin; Weiss, Mitchell J.; Cheng, Xiaodong; Shi, Junwei; Blobel, Gerd A.
Genome editing of HBG1 and HBG2 to induce fetal hemoglobin
BLOOD ADVANCES
IF7.1
2019-11-06132
OA
Metais, Jean-Yves; Doerfler, Phillip A.; Mayuranathan, Thiyagaraj; Bauer, Daniel E.; Fowler, Stephanie C.; Hsieh, Matthew M.; Katta, Varun; Keriwala, Sagar; Lazzarotto, Cicera R.; Luk, Kevin; Neel, Michael D.; Perry, S. Scott; Peters, Samuel T.; Porter, Shaina N.; Ryu, Byoung Y.; Sharma, Akshay; Shea, Devlin; Tisdale, John F.; Uchida, Naoya; Wolfe, Scot A.; Woodard, Kaitly J.; Wu, Yuxuan; Yao, Yu; Zeng, Jing; Pruett-Miller, Shondra; Tsai, Shengdar Q.; Weiss, Mitchell J.

研究方向

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M
Mitchell J. Weiss
H 指数:87论文数:451被引数:2.7万
K
Kalin Mayberry
H 指数:11论文数:27被引数:1,009
Y
Yong Cheng
H 指数:41论文数:129被引数:1.9万
P
Phillip A. Doerfler
H 指数:15论文数:34被引数:1,411
Y
Yu Yao
H 指数:33论文数:139被引数:4,538
Y
Yichao Li
H 指数:27论文数:143被引数:2,734
J
Jonathan Yen
H 指数:21论文数:60被引数:2,996
R
Ruopeng Feng
H 指数:17论文数:64被引数:1,233
J
John F. Tisdale
H 指数:62论文数:436被引数:1.6万
S
Senthil Velan Bhoopalan
H 指数:11论文数:72被引数:629