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K

Keiko Hikino

riken center for integrative medical sciences
H指数:14
被引数:690

个人简介

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Decomposing population differences in type 2 diabetes through a high-resolution GWAS of ~600,000 individuals with East Asian ancestry

通过约60万具有东亚血统个体的超高分辨率全基因组关联研究分解2型糖尿病人群差异

Communications Biology
IF5.1
2026-09-300
OAAI
Kohei Saito; Hsing-Fang Lu; Tatsuhide Inoue; Takeshi Usui; Toshihiro Shirai; Tatsuo Ogawa; Rieko Kosugi; Chika Kyo; Keiko Hikino; Yun Li; Momoko Horikoshi; Hiroshi Itoh; Kaori Hayashi; Toshio Shimada; Koichi Ozaki; Issei Tanaka; Wen-Ling Liao; Yen-Ting Chang; Ting-Yuan Liu; Fuu-Jen Tsai; Chikashi Terao
Multi-population GWAS meta-analysis identifies bladder cancer susceptibility loci and highlights genetic regulation of smoking-related risk

多群体全基因组关联研究荟萃分析鉴定膀胱癌易感位点并突出吸烟相关风险的遗传调控

Nature Communications
IF15.7
2026-08-080
OA
Ludmila Prokunina-Olsson; Oscar Florez-Vargas; Michael G. Levin; Diptavo Dutta; Charles E. Breeze; Lauren M. Hurwitz; Wusheng Yan; Philippe Lamy; Brenen W. Papenberg; Kevin Wang; Chia-Han Lee; Roger L. Milne; Jian Gu; Caroline Y. Um; Vijai Joseph; Helena Furberg; Florence Le Calvez-Kelm; Adriana Lori; Parichoy Pal Choudhury; Nina Afshar; Manolis Kogevinas; Kenneth Offit; Sita H. Vermeulen; Evangelina López de Maturana; Demetrius Albanes; Mark P. Purdue; Victoria K. Cortessis; Margaret R. Karagas; Charles Kooperberg; Marc Bjurlin; Deborah A. Tadesse; Steven C. Moore; Wen-Yi Huang; Christopher A. Haiman; Mariana C. Stern; A. Heather Eliassen; Lorelei A. Mucci; Katja K. Aben; Tessel E. Galesloot; Anurag Verma; Soichiro Yoshino; Keiko Hikino; Chikashi Terao; Thorunn Rafnar; Koichi Matsuda; Taro Shuin; Montserrat Garcia-Closas; Francisco X. Real; Lambertus A. Kiemeney; Stephen J. Chanock; Núria Malats; Debra T. Silverman; Lars Dyrskjot; Nathaniel Rothman; Scott M. Damrauer; Stella Koutros; Jeffrey S. Damrauer
Publisher Correction: Multi-ancestry genome-wide association analyses of refractive error augment genetic discovery and polygenic prediction

出版商更正：多祖先基因组-wide关联分析增强了屈光不正的遗传发现和多基因预测

Nature Genetics
IF29
2026-06-010
OAAI
Fei-Fei Cheng; Xiaoxi Liu; Hao Mi; Lizhong Wang; Ruilei Ma; Yazhou Guo; Julia Sidorenko; Chen Jiang; Tania Islam; Akira Meguro; Keiko Hikino; Yuki Ishikawa; Senwei Tang; Teng Li; Ruoyan Chen; Likun Wang; Reedik Mägi; Andres Metspalu; Masaki Takeuchi; Nobuhisa Mizuki; Hélène Choquet; Zi-Bing Jin; Gang Chen; Kun Zhou; Chikashi Terao; Jian Zeng; Jian Yang
Multi-ancestry genome-wide association analyses of refractive error augment genetic discovery and polygenic prediction

屈光不正的多祖先全基因组关联分析增强遗传发现和多基因预测

Nature Genetics
IF29
2026-04-200
OAAI
Fei-Fei Cheng; Xiaoxi Liu; Hao Mi; Lizhong Wang; Ruilei Ma; Yazhou Guo; Julia Sidorenko; Chen Jiang; Tania Islam; Akira Meguro; Keiko Hikino; Yuki Ishikawa; Senwei Tang; Teng Li; Ruoyan Chen; Likun Wang; Reedik Mägi; Andres Metspalu; Masaki Takeuchi; Nobuhisa Mizuki; Hélène Choquet; Zi-Bing Jin; Gang Chen; Kun Zhou; Chikashi Terao; Jian Zeng; Jian Yang
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 Genotype and Use of 5-HT3 Receptor Antagonists: 2026 Update

CPIC临床药物基因组学实施联盟关于CYP2D6基因型与5-HT3受体拮抗剂使用的指南：2026年更新

CLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
2026-04-010
OAAI
Moore, Claire; Bourque, Melissa S.; Halman, Andreas; Agundez, Jose A. G.; Prows, Cynthia A.; Hikino, Keiko; Schwab, Matthias; Oxencis, Carolyn J.; Chauhan, Dharmisha; Diekstra, Meta H. M.; Long, Susie E.; Bell, Gillian C.; Gaedigk, Andrea; Whirl-Carrillo, Michelle; Klein, Teri E.; Caudle, Kelly E.; Conyers, Rachel
Author Correction: GWAS for systemic sclerosis identifies six novel susceptibility loci including one in the Fcγ receptor region

作者更正: 系统性硬化症的ghis确定了六个新的易感位点，包括fc γ 受体区域中的一个

Nature Communications
IF15.7
2026-01-190
OAAI
Yuki Ishikawa; Nao Tanaka; Yoshihide Asano; Masanari Kodera; Yuichiro Shirai; Mitsuteru Akahoshi; Minoru Hasegawa; Takashi Matsushita; Kazuyoshi Saito; Sei-ichiro Motegi; Hajime Yoshifuji; Ayumi Yoshizaki; Tomohiro Kohmoto; Kae Takagi; Akira Oka; Miho Kanda; Yoshihito Tanaka; Yumi Ito; Kazuhisa Nakano; Hiroshi Kasamatsu; Akira Utsunomiya; Akiko Sekiguchi; Hiroaki Niiro; Masatoshi Jinnin; Katsunari Makino; Takamitsu Makino; Hironobu Ihn; Motohisa Yamamoto; Chisako Suzuki; Hiroki Takahashi; Emi Nishida; Akimichi Morita; Toshiyuki Yamamoto; Manabu Fujimoto; Yuya Kondo; Daisuke Goto; Takayuki Sumida; Naho Ayuzawa; Hidetoshi Yanagida; Tetsuya Horita; Tatsuya Atsumi; Hirahito Endo; Yoshihito Shima; Atsushi Kumanogoh; Jun Hirata; Nao Otomo; Hiroyuki Suetsugu; Yoshinao Koike; Kohei Tomizuka; Soichiro Yoshino; Xiaoxi Liu; Shuji Ito; Keiko Hikino; Akari Suzuki; Yukihide Momozawa; Shiro Ikegawa; Yoshiya Tanaka; Osamu Ishikawa; Kazuhiko Takehara; Takeshi Torii; Shinichi Sato; Yukinori Okada; Tsuneyo Mimori; Fumihiko Matsuda; Koichi Matsuda; Tiffany Amariuta; Issei Imoto; Keitaro Matsuo; Masataka Kuwana; Yasushi Kawaguchi; Koichiro Ohmura; Chikashi Terao
Population-specific putative causal variants shape quantitative traits
NATURE GENETICS
IF31.8
2024-10-031
OAAI
Koyama, Satoshi; Liu, Xiaoxi; Koike, Yoshinao; Hikino, Keiko; Koido, Masaru; Li, Wei; Akaki, Kotaro; Tomizuka, Kohei; Ito, Shuji; Otomo, Nao; Suetsugu, Hiroyuki; Yoshino, Soichiro; Akiyama, Masato; Saito, Kohei; Ishikawa, Yuki; Benner, Christian; Natarajan, Pradeep; Ellinor, Patrick T.; Mushiroda, Taisei; Horikoshi, Momoko; Ikeda, Masashi; Iwata, Nakao; Matsuda, Koichi; Niida, Shumpei; Ozaki, Kouichi; Momozawa, Yukihide; Ikegawa, Shiro; Takeuchi, Osamu; Ito, Kaoru; Terao, Chikashi
A genome-wide association study identifies a locus associated with knee extension strength in older Japanese individuals
COMMUNICATIONS BIOLOGY
IF5.1
2024-05-201
OAAI
Ito, Shuji; Takuwa, Hiroshi; Kakehi, Saori; Someya, Yuki; Kaga, Hideyoshi; Kumahashi, Nobuyuki; Kuwata, Suguru; Wakatsuki, Takuya; Kadowaki, Masaru; Yamamoto, Soichiro; Abe, Takafumi; Takeda, Miwako; Ishikawa, Yuki; Liu, Xiaoxi; Otomo, Nao; Suetsugu, Hiroyuki; Koike, Yoshinao; Hikino, Keiko; Tomizuka, Kohei; Momozawa, Yukihide; Ozaki, Kouichi; Isomura, Minoru; Nabika, Toru; Kaneko, Haruka; Ishijima, Muneaki; Kawamori, Ryuzo; Watada, Hirotaka; Tamura, Yoshifumi; Uchio, Yuji; Ikegawa, Shiro; Terao, Chikashi
Multi-ancestry genome-wide association study of kidney cancer identifies 63 susceptibility regions

肾癌的多祖先全基因组关联研究确定了63个易感区域

NATURE GENETICS
IF31.8
2024-04-262
PRE
Purdue, Mark P.; Dutta, Diptavo; Machiela, Mitchell J.; Gorman, Bryan R.; Winter, Timothy; Okuhara, Dayne; Cleland, Sara; Ferreiro-Iglesias, Aida; Scheet, Paul; Liu, Aoxing; Wu, Chao; Antwi, Samuel O.; Larkin, James; Zequi, Stenio C.; Sun, Maxine; Hikino, Keiko; Hajiran, Ali; Lawson, Keith A.; Carcano, Flavio; Blanchet, Odile; Shuch, Brian; Nepple, Kenneth G.; Margue, Gaelle; Sundi, Debasish; Diver, W. Ryan; Folgueira, Maria A. A. K.; van Bokhoven, Adrie; Neffa, Florencia; Brown, Kevin M.; Hofmann, Jonathan N.; Rhee, Jongeun; Yeager, Meredith; Cole, Nathan R.; Hicks, Belynda D.; Manning, Michelle R.; Hutchinson, Amy A.; Rothman, Nathaniel; Huang, Wen-Yi; Linehan, W. Marston; Lori, Adriana; Ferragu, Matthieu; Zidane-Marinnes, Merzouka; Serrano, Sergio V.; Magnabosco, Wesley J.; Vilas, Ana; Decia, Ricardo; Carusso, Florencia; Graham, Laura S.; Anderson, Kyra; Bilen, Mehmet A.; Arciero, Cletus; Pellegrin, Isabelle; Ricard, Solene; Scelo, Ghislaine; Banks, Rosamonde E.; Vasudev, Naveen S.; Soomro, Naeem; Stewart, Grant D.; Adeyoju, Adebanji; Bromage, Stephen; Hrouda, David; Gibbons, Norma; Patel, Poulam; Sullivan, Mark; Protheroe, Andrew; Nugent, Francesca I.; Fournier, Michelle J.; Zhang, Xiaoyu; Martin, Lisa J.; Komisarenko, Maria; Eisen, Timothy; Cunningham, Sonia A.; Connolly, Denise C.; Uzzo, Robert G.; Zaridze, David; Mukeria, Anush; Holcatova, Ivana; Hornakova, Anna; Foretova, Lenka; Janout, Vladimir; Mates, Dana; Jinga, Viorel; Rascu, Stefan; Mijuskovic, Mirjana; Savic, Slavisa; Milosavljevic, Sasa; Gaborieau, Valerie; Abedi-Ardekani, Behnoush; Mckay, James; Johansson, Mattias; Phouthavongsy, Larry; Hayman, Lindsay; Li, Jason; Lungu, Ilinca; Bezerra, Stephania M.; Souza, Aline G.; Sares, Claudia T. G.; Reis, Rodolfo B.; Gallucci, Fabio P.; Cordeiro, Mauricio D.; Pomerantz, Mark; Lee, Gwo-Shu M.; Freedman, Matthew L.; Jeong, Anhyo; Greenberg, Samantha E.; Sanchez, Alejandro; Thompson, R. Houston; Sharma, Vidit; Thiel, David D.; Ball, Colleen T.; Abreu, Diego; Lam, Elaine T.; Nahas, William C.; Master, Viraj A.; Patel, Alpa V.; Bernhard, Jean-Christophe; Freedman, Neal D.; Bigot, Pierre; Reis, Rui M.; Colli, Leandro M.; Finelli, Antonio; Manley, Brandon J.; Terao, Chikashi; Choueiri, Toni K.; Carraro, Dirce M.; Houlston, Richard; Eckel-Passow, Jeanette E.; Abbosh, Philip H.; Ganna, Andrea; Brennan, Paul; Gu, Jian; Chanock, Stephen J.
GWAS for systemic sclerosis identifies six novel susceptibility loci including one in the Fcγ receptor region
NATURE COMMUNICATIONS
IF15.7
2024-01-314
OAAI
Ishikawa, Yuki; Tanaka, Nao; Asano, Yoshihide; Kodera, Masanari; Shirai, Yuichiro; Akahoshi, Mitsuteru; Hasegawa, Minoru; Matsushita, Takashi; Saito, Kazuyoshi; Motegi, Sei-ichiro; Yoshifuji, Hajime; Yoshizaki, Ayumi; Kohmoto, Tomohiro; Takagi, Kae; Oka, Akira; Kanda, Miho; Tanaka, Yoshihito; Ito, Yumi; Nakano, Kazuhisa; Kasamatsu, Hiroshi; Utsunomiya, Akira; Sekiguchi, Akiko; Niiro, Hiroaki; Jinnin, Masatoshi; Makino, Katsunari; Makino, Takamitsu; Ihn, Hironobu; Yamamoto, Motohisa; Suzuki, Chisako; Takahashi, Hiroki; Nishida, Emi; Morita, Akimichi; Yamamoto, Toshiyuki; Fujimoto, Manabu; Kondo, Yuya; Goto, Daisuke; Sumida, Takayuki; Ayuzawa, Naho; Yanagida, Hidetoshi; Horita, Tetsuya; Atsumi, Tatsuya; Endo, Hirahito; Shima, Yoshihito; Kumanogoh, Atsushi; Hirata, Jun; Otomo, Nao; Suetsugu, Hiroyuki; Koike, Yoshinao; Tomizuka, Kohei; Yoshino, Soichiro; Liu, Xiaoxi; Ito, Shuji; Hikino, Keiko; Suzuki, Akari; Momozawa, Yukihide; Ikegawa, Shiro; Tanaka, Yoshiya; Ishikawa, Osamu; Takehara, Kazuhiko; Torii, Takeshi; Sato, Shinichi; Okada, Yukinori; Mimori, Tsuneyo; Matsuda, Fumihiko; Matsuda, Koichi; Amariuta, Tiffany; Imoto, Issei; Matsuo, Keitaro; Kuwana, Masataka; Kawaguchi, Yasushi; Ohmura, Koichiro; Terao, Chikashi
Genetic insights into ossification of the posterior longitudinal ligament of the spine
ELIFE
IF0
2023-07-1812
OA
Koike, Yoshinao; Takahata, Masahiko; Nakajima, Masahiro; Otomo, Nao; Suetsugu, Hiroyuki; Liu, Xiaoxi; Endo, Tsutomu; Imagama, Shiro; Kobayashi, Kazuyoshi; Kaito, Takashi; Kato, Satoshi; Kawaguchi, Yoshiharu; Kanayama, Masahiro; Sakai, Hiroaki; Tsuji, Takashi; Miyamoto, Takeshi; Inose, Hiroyuki; Yoshii, Toshitaka; Kashii, Masafumi; Nakashima, Hiroaki; Ando, Kei; Taniguchi, Yuki; Takeuchi, Kazuhiro; Ito, Shuji; Tomizuka, Kohei; Hikino, Keiko; Iwasaki, Yusuke; Kamatani, Yoichiro; Maeda, Shingo; Nakajima, Hideaki; Mori, Kanji; Seichi, Atsushi; Fujibayashi, Shunsuke; Kanchiku, Tsukasa; Watanabe, Kei; Tanaka, Toshihiro; Kida, Kazunobu; Kobayashi, Sho; Takahashi, Masahito; Yamada, Kei; Takuwa, Hiroshi; Lu, Hsing-Fang; Niida, Shumpei; Ozaki, Kouichi; Momozawa, Yukihide; Yamazaki, Masashi; Okawa, Atsushi; Matsumoto, Morio; Iwasaki, Norimasa; Terao, Chikashi; Ikegawa, Shiro
Mobile element variation contributes to population-specific genome diversification, gene regulation and disease risk
NATURE GENETICS
IF31.8
2023-05-1118
OA
Kojima, Shohei; Koyama, Satoshi; Ka, Mirei; Saito, Yuka; Parrish, Erica; Endo, Mikiko; Takata, Sadaaki; Mizukoshi, Misaki; Hikino, Keiko; Takeda, Atsushi; Gelinas, Asami; Heaton, Steven; Koide, Rie; Kamada, Anselmo F.; Noguchi, Michiya; Hamada, Michiaki; Biobank Japan Project Consortium; Kamatani, Yoichiro; Murakawa, Yasuhiro; Ishigaki, Kazuyoshi; Nakamura, Yukio; Ito, Kaoru; Terao, Chikashi; Momozawa, Yukihide; Parrish, Nicholas F.

研究方向

暂未获取到该数据
C
Chikashi Terao
H 指数:61论文数:485被引数:2.3万
Y
Yuki Ishikawa
H 指数:19论文数:71被引数:1,622
K
Kohei Tomizuka
H 指数:13论文数:35被引数:661
X
Xiaoxi Liu
H 指数:42论文数:304被引数:8,378
T
Taisei Mushiroda
H 指数:55论文数:317被引数:1.0万
Y
Yoshinao Koike
H 指数:15论文数:79被引数:635
S
Shuji Ito
H 指数:16论文数:61被引数:1,144
M
Masaru Koido
H 指数:20论文数:87被引数:3,621
Y
Yukihide Momozawa
H 指数:65论文数:559被引数:1.8万
Y
Yoichiro Kamatani
H 指数:112论文数:556被引数:6.3万