Robert L. Walker - Publications, H-index & Citations

Robert L. Walker

national institutes of health (nih) - usa

60H指数

556论文数

1.4W被引数

收录论文 97

发表时间

Cancer-Associated DAXX Mutations Reveal a Critical Role for ATRX Localization in ALT Suppression

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2025-12-01

PREAI

Soper, Sarah F. Clatterbuck; Walker, Robert L.; Pineda, Marbin A.; Zhu, Yuelin J.; Dalgleish, James L. T.; Wang, Jasmine; Meltzer, Paul S.

Disruption of normal stem cell function and transmission of myelodysplastic syndrome by self-renewal of committed myeloid lineage cells 通过定向髓系谱系细胞的自我更新，破坏正常干细胞功能并传播骨髓增生异常综合征

Stem Cell Reports

IF5.1

2025-07-03

OAAI

Yang Jo Chung; Ryan Bertoli; Dengchao Cao; Robert L. Walker; Yuelin Jack Zhu; Paul Meltzer; Peter D. Aplan

Inhibition of discoidin domain receptor 1 as a new therapeutic strategy for osteosarcoma

FASEB JOURNAL

IF4.2

2024-12-06

PREAI

Wang, Jinglu; Walker, Robert L.; Hornicek, Francis J.; Shi, Huirong; Duan, Zhenfeng

Transcriptional regulation and therapeutic potential of cyclin-dependent kinase 9 (CDK9) in sarcoma 细胞周期蛋白依赖性激酶9 (CDK9) 在肉瘤中的转录调控和治疗潜力

BIOCHEMICAL PHARMACOLOGY

IF5.6

2024-08-01

PREAI

Walker, Robert L.; Hornicek, Francis J.; Duan, Zhenfeng

The DNA Methyltransferase Inhibitor 5-Aza-4′-thio-2′-Deoxycytidine Induces C>G Transversions and Acute Lymphoid Leukemia Development

CANCER RESEARCH

IF16.6

2024-06-04

PREAI

Bertoli, Ryan M.; Chung, Yang Jo; Difilippantonio, Michael J.; Wokasch, Anthony; Marasco, Madison R. B.; Klimaszewski, Haley; Gammell, Susannah; Zhu, Yuelin J.; Walker, Robert L.; Cao, Dengchao; Khanna, Ajay; Walter, Matthew J.; Doroshow, James H.; Meltzer, Paul S.; Aplan, Peter D.

Native nanopore sequencing of multiple tumor sites reveals genetic and epigenetic intra-tumor heterogeneity in canine osteosarcoma

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Keskus, Ayse; Aganezov, Sergey; Ahmad, Tanveer; Dai, Xiaoguang; Walker, Robert; Beaulaurier, John; Hickey, Scott; Juul, Sissel; LeBlanc, Amy Kathleen; Meltzer, Paul S.; Kolmogorov, Mikhail

5-Aza-4'-thio-2'-deoxycytidine induces C to G transversions in a specific trinucleotide context and leads to acute lymphoid leukemia

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Bertoli, Ryan Matthew; Chung, Yang Jo; Difilippantonio, Michael; Wokasch, Anthony; Marasco, Madison R.; Klimaszewski, Haley; Garber, Susannah; Zhu, Yuelin Jack; Walker, Robert L.; Cao, Dengchao; Doroshow, James; Meltzer, Paul; Aplan, Peter D.

Conical drill bit for optimized external ventricular drain placement: a proof-of-concept study

JOURNAL OF NEUROSURGERY

IF3.6

2023-09-01

PREAI

Ravina, Kristine; Yang, Natalia; Brocoum, Sophia; Pasco-Anderson, Julia; Walker, Robert L.; Khan, Marina; Cabodi, Mario; Holsapple, James

NUP98::Nsd1 and FLT3-ITD collaborate to generate acute myeloid leukemia

LEUKEMIA

IF13.4

2023-05-05

OAAI

Matsukawa, Toshihiro; Yin, Mianmian; Nigam, Nupur; Negi, Vijay; Li, Li; Small, Donald; Zhu, Yuelin J.; Walker, Robert L.; Meltzer, Paul S.; Aplan, Peter D.

Loss of LRRC15 in osteosarcoma cells disrupts extracellular matrix integration, intercellular communication, and differentiation

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Mukherjee, Sanjit; Jajoo, Ankit; Zhu, Jack; Pineda, Marbin; Walker, Robert; Purcell, James; Helman, Lee J.; Meltzer, Paul S.

An unliganded thyroid hormone p receptor activates the cyclin D1/cyclin-dependent kinase/retinoblastoma/E2F pathway and induces pituitary tumorigenesis

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

105

OAAI

Furumoto, H; Ying, H; Chandramouli, GVR; Zhao, L; Walker, RL; Meltzer, PS; Willingham, MC; Cheng, SY

A p21-ZEB1 Complex Inhibits Epithelial-Mesenchymal Transition through the MicroRNA 183-96-182 Cluster

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

OAAI

Li, Xiao Ling; Hara, Toshifumi; Choi, Youngeun; Subramanian, Murugan; Francis, Princy; Bilke, Sven; Walker, Robert L.; Pineda, Marbin; Zhu, Yuelin; Yang, Yuan; Luo, Ji; Wakefield, Lalage M.; Brabletz, Thomas; Park, Ben Ho; Sharma, Sudha; Chowdhury, Dipanjan; Meltzer, Paul S.; Lal, Ashish

Genome-Wide Analysis of the FOXA1 Transcriptional Network Identifies Novel Protein-Coding and Long Noncoding RNA Targets in Colorectal Cancer Cells

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-03

OAAI

Lazar, Sarah B.; Pongor, Lorinc; Li, Xiao Ling; Grammatikakis, Ioannis; Muys, Bruna R.; Dangelmaier, Emily A.; Redon, Christophe E.; Jang, Sang-Min; Walker, Robert L.; Tang, Wei; Ambs, Stefan; Harris, Curtis C.; Meltzer, Paul S.; Aladjem, Mirit, I; Lal, Ashish

Advances in the development of chordoma models for drug discovery and precision medicine 用于药物发现和精准医学的脊索瘤模型的开发进展

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

IF8.3

2022-11-01

PREAI

Walker, Robert L.; Hornicek, Francis J.; Duan, Zhenfeng

Mcm2 hypomorph leads to acute leukemia or hematopoietic stem cell failure, dependent on genetic context

FASEB JOURNAL

IF4.2

2022-08-03

OAAI

Matsukawa, Toshihiro; Yin, Mianmian; Baslan, Timour; Chung, Yang Jo; Cao, Dengchao; Bertoli, Ryan; Zhu, Yuelin J.; Walker, Robert L.; Freeland, Amy; Knudsen, Erik; Lowe, Scott W.; Meltzer, Paul S.; Aplan, Peter D.

Mutant Idh2 Cooperates with a NUP98-HOXD13 Fusion to Induce Early Immature Thymocyte Precursor ALL

CANCER RESEARCH

IF16.6

2021-07-28

OAAI

Goldberg, Liat; Negi, Vijay; Chung, Yang Jo; Onozawa, Masahiro; Zhu, Yuelin J.; Walker, Robert L.; Pierce, Rachel; Patel, Daxesh P.; Krausz, Kristopher W.; Gonzalez, Frank J.; Goodell, Margaret A.; Rodriguez, Benjamin A. T.; Meltzer, Paul S.; Aplan, Peter D.

A small protein encoded by a putative lncRNA regulates apoptosis and tumorigenicity in human colorectal cancer cells

ELIFE

IF0

2020-10-28

OAAI

Li, Xiao Ling; Pongor, Lorinc; Tang, Wei; Das, Sudipto; Muys, Bruna R.; Jones, Matthew F.; Lazar, Sarah B.; Dangelmaier, Emily A.; Hartford, Corrine C. R.; Grammatikakis, Ioannis; Hao, Qinyu; Sun, Qinyu; Schetter, Aaron; Martindale, Jennifer L.; Tang, BinWu; Jenkins, Lisa M.; Robles, Ana, I; Walker, Robert L.; Ambs, Stefan; Chari, Raj; Shabalina, Svetlana A.; Gorospe, Myriam; Hussain, S. Perwez; Harris, Curtis C.; Meltzer, Paul S.; Prasanth, Kannanganattu, V; Aladjem, Mirit, I; Andresson, Thorkell; Lal, Ashish

Distinct DNA Methylation Signatures in Neuroendocrine Tumors Specific for Primary Site and Inherited Predisposition 神经内分泌肿瘤中独特的DNA甲基化特征特异于原发部位和遗传易感性

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

IF5.1

2020-07-24

OAAI

Tirosh, Amit; Killian, Jonathan Keith; Petersen, David; Zhu, Yuelin Jack; Walker, Robert L.; Blau, Jenny E.; Nilubol, Naris; Patel, Dhaval; Agarwal, Sunita K.; Weinstein, Lee Scott; Meltzer, Paul; Kebebew, Electron

Deposition of Centromeric Histone H3 Variant CENP-A/Cse4 into Chromatin Is Facilitated by Its C-Terminal Sumoylation

GENETICS

IF5.1

2020-04-01

OAAI

Ohkuni, Kentaro; Suva, Evelyn; Au, Wei-Chun; Walker, Robert L.; Levy-Myers, Reuben; Meltzer, Paul S.; Baker, Richard E.; Basrai, Munira A.

A unique mutator phenotype reveals complementary oncogenic lesions leading to acute leukemia

JCI INSIGHT

IF6.1

2019-12-05

OAAI

Yin, Mianmian; Baslan, Timour; Walker, Robert L.; Zhu, Yuelin J.; Freeland, Amy; Matsukawa, Toshihiro; Sridharan, Sriram; Nussenzweig, Andre; Pruitt, Steven C.; Lowe, Scott W.; Meltzer, Paul S.; Aplan, Peter D.

研究方向