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S227928: A Novel Anti-CD74 ADC with MCL-1 Inhibitor Payload for the Treatment of Acute Myeloid Leukemia (AML) and Other Hematologic Malignancies S227928：一种新型的抗CD74抗体药物偶联物（ADC），其载药为MCL-1抑制剂，用于治疗急性髓系白血病（AML）及其他血液系统恶性肿瘤 Maragno, Ana-Leticia; Seiss, Katherine; Newcombe, Rick; Mistry, Prakash; Schnell, Christian R.; Von Arx, Fabian; Koenig, Julie; Malamas, Anthony S.; Le Toumelin-Braizat, Gaetane; Bresson, Laura; Rocchetti, Francesca; Demarles, Didier; Kurth, Esther; Renteria, Lorena; Hainzl, Dominik; Engelhardt, Volker; Liot, Caroline; Madelain, Vincent; Kostova, Vesela; Starck, Jerome-Benoit; Valour, Damien; Franzetti, Georges-Alain; Colland, Frederic; Vostiarova, Helena; Tschantz, William R.; Bachmann, Nicholas; Palacio-Ramirez, Sebastian; Burger, Matthew; Campbell, Jennifer M.; Chen, Zhuoliang; Koenig, Robert; Mcneill, Eric; Mo, Ruowei; Nakajima, Katsumasa; Palermo, Mark; Shen, Yiping; Yu, Bing; Zambrowski, Mark; Zhang, Alan; Zecri, Frederic; Broniscer, Alberto; Geneste, Olivier; Horton, Kristin; D'Alessio, Joseph A. 分享 收藏
High-grade glioma in infants and young children is histologically, molecularly, and clinically diverse: Results from the SJYC07 trial and institutional experience Chiang, Jason; Bagchi, Aditi; Li, Xiaoyu; Dhanda, Sandeep K.; Huang, Jie; Pinto, Soniya N.; Sioson, Edgar; Dalton, James; Tatevossian, Ruth G.; Jia, Sujuan; Partap, Sonia; Fisher, Paul G.; Bowers, Daniel C.; Hassall, Timothy E. G.; Lu, Congyu; Zaldivar-Peraza, Airen; Wright, Karen D.; Broniscer, Alberto; Qaddoumi, Ibrahim; Upadhyaya, Santhosh A.; Vinitsky, Anna; Sabin, Noah D.; Orr, Brent A.; Klimo Jr, Paul; Boop, Frederick A.; Ashford, Jason M.; Conklin, Heather M.; Onar-Thomas, Arzu; Zhou, Xin; Ellison, David W.; Gajjar, Amar; Robinson, Giles W. 分享 收藏
A neurodevelopmental epigenetic programme mediated by SMARCD3-DAB1-Reelin signalling is hijacked to promote medulloblastoma metastasis Zou, Han; Poore, Bradley; Brown, Emily E.; Qian, Jieqi; Xie, Bin; Asimakidou, Evridiki; Razskazovskiy, Vladislav; Ayrapetian, Deanna; Sharma, Vaibhav; Xia, Shunjin; Liu, Fei; Chen, Apeng; Guan, Yongchang; Li, Zhengwei; Wanggou, Siyi; Saulnier, Olivier; Ly, Michelle; Fellows-Mayle, Wendy; Xi, Guifa; Tomita, Tadanori; Resnick, Adam C.; Mack, Stephen C.; Raabe, Eric H.; Eberhart, Charles G.; Sun, Dandan; Stronach, Beth E.; Agnihotri, Sameer; Kohanbash, Gary; Lu, Songjian; Herrup, Karl; Rich, Jeremy N.; Gittes, George K.; Broniscer, Alberto; Hu, Zhongliang; Li, Xuejun; Pollack, Ian F.; Friedlander, Robert M.; Hainer, Sarah J.; Taylor, Michael D.; Hu, Baoli 分享 收藏
Molecular classification and outcome of children with rare CNS embryonal tumors: results from St. Jude Children's Research Hospital including the multi-center SJYC07 and SJMB03 clinical trials Liu, Anthony P. Y.; Dhanda, Sandeep K.; Lin, Tong; Sioson, Edgar; Vasilyeva, Aksana; Gudenas, Brian; Tatevossian, Ruth G.; Jia, Sujuan; Neale, Geoffrey; Bowers, Daniel C.; Hassall, Tim; Partap, Sonia; Crawford, John R.; Chintagumpala, Murali; Bouffet, Eric; McCowage, Geoff; Broniscer, Alberto; Qaddoumi, Ibrahim; Armstrong, Greg; Wright, Karen D.; Upadhyaya, Santhosh A.; Vinitsky, Anna; Tinkle, Christopher L.; Lucas, John; Chiang, Jason; Indelicato, Daniel J.; Sanders, Robert; Klimo, Paul, Jr.; Boop, Frederick A.; Merchant, Thomas E.; Ellison, David W.; Northcott, Paul A.; Orr, Brent A.; Zhou, Xin; Onar-Thomas, Arzu; Gajjar, Amar; Robinson, Giles W. 分享 收藏
Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome (vol 3, pg 629, 2022) Golbourn, Brian J.; Halbert, Matthew E.; Halligan, Katharine; Varadharajan, Srinidhi; Krug, Brian; Mbah, Nneka E.; Kabir, Nisha; Stanton, Ann-Catherine J.; Locke, Abigail L.; Casillo, Stephanie M.; Zhao, Yanhua; Sanders, Lauren M.; Cheney, Allison; Mullett, Steven J.; Chen, Apeng; Wassell, Michelle; Andren, Anthony; Perez, Jennifer; Jane, Esther P.; Premkumar, Daniel R. David; Koncar, Robert F.; Mirhadi, Shideh; McCarl, Lauren H.; Chang, Yue-Fang; Wu, Yijen L.; Gatesman, Taylor A.; Cruz, Andrea F.; Zapotocky, Michal; Hu, Baoli; Kohanbash, Gary; Wang, Xiuxing; Vartanian, Alenoush; Moran, Michael F.; Lieberman, Frank; Amankulor, Nduka M.; Wendell, Stacy G.; Vaske, Olena M.; Panigrahy, Ashok; Felker, James; Bertrand, Kelsey C.; Kleinman, Claudia L.; Rich, Jeremy N.; Friedlander, Robert M.; Broniscer, Alberto; Lyssiotis, Costas; Jabado, Nada; Pollack, Ian F.; Mack, Stephen C.; Agnihotri, Sameer 分享 收藏
Phase II study of alisertib as a single agent for treating recurrent or progressive atypical teratoid/rhabdoid tumor Upadhyaya, Santhosh A.; Campagne, Olivia; Billups, Catherine A.; Orr, Brent A.; Onar-Thomas, Arzu; Tatevossian, Ruth G.; Mostafavi, Roya; Myers, Jason R.; Vinitsky, Anna; Moreira, Daniel C.; Lindsay, Holly B.; Kilburn, Lindsay; Baxter, Patricia; Smith, Amy; Crawford, John R.; Partap, Sonia; Bendel, Anne E.; Aguilera, Dolly G.; Nichols, Kim E.; Rampersaud, Evadnie; Ellison, David W.; Klimo, Paul, Jr.; Patay, Zoltan; Robinson, Giles W.; Broniscer, Alberto; Stewart, Clinton F.; Wetmore, Cynthia; Gajjar, Amar 分享 收藏
Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome Golbourn, Brian J.; Halbert, Matthew E.; Halligan, Katharine; Varadharajan, Srinidhi; Krug, Brian; Mbah, Nneka E.; Kabir, Nisha; Stanton, Ann-Catherine J.; Locke, Abigail L.; Casillo, Stephanie M.; Zhao, Yanhua; Sanders, Lauren M.; Cheney, Allison; Mullett, Steven J.; Chen, Apeng; Wassell, Michelle; Andren, Anthony; Perez, Jennifer; Jane, Esther P.; Premkumar, Daniel R. David; Koncar, Robert F.; Mirhadi, Shideh; McCarl, Lauren H.; Chang, Yue-Fang; Wu, Yijen L.; Gatesman, Taylor A.; Cruz, Andrea F.; Zapotocky, Michal; Hu, Baoli; Kohanbash, Gary; Wang, Xiuxing; Vartanian, Alenoush; Moran, Michael F.; Lieberman, Frank; Amankulor, Nduka M.; Wendell, Stacy G.; Vaske, Olena M.; Panigrahy, Ashok; Felker, James; Bertrand, Kelsey C.; Kleinman, Claudia L.; Rich, Jeremy N.; Friedlander, Robert M.; Broniscer, Alberto; Lyssiotis, Costas; Jabado, Nada; Pollack, Ian F.; Mack, Stephen C.; Agnihotri, Sameer 分享 收藏
Phase I study using crenolanib to target PDGFR kinase in children and young adults with newly diagnosed DIPG or recurrent high-grade glioma, including DIPG Tinkle, Christopher L.; Broniscer, Alberto; Chiang, Jason; Campagne, Olivia; Huang, Jie; Orr, Brent A.; Li, Xiaoyu; Patay, Zoltan; Zhang, Jinghui; Baker, Suzanne J.; Merchant, Thomas E.; Jain, Vinay; Onar-Thomas, Arzu; Stewart, Clinton F.; Wetmore, Cynthia; Gajjar, Amar 分享 收藏
11C-Methionine PET for Identification of Pediatric High-Grade Glioma Recurrence 11c-蛋氨酸PET鉴别小儿高级别胶质瘤复发 Bag, Asim K.; Wing, Melissa N.; Sabin, Noah D.; Hwang, Scott N.; Armstrong, Gregory T.; Han, Yuanyuan; Li, Yimei; Snyder, Scott E.; Robinson, Giles W.; Qaddoumi, Ibrahim; Broniscer, Alberto; Lucas, John T.; Shulkin, Barry L. 分享 收藏
Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma He, Chen; Xu, Ke; Zhu, Xiaoyan; Dunphy, Paige S.; Gudenas, Brian; Lin, Wenwei; Twarog, Nathaniel; Hover, Laura D.; Kwon, Chang-Hyuk; Kasper, Lawryn H.; Zhang, Junyuan; Li, Xiaoyu; Dalton, James; Jonchere, Barbara; Mercer, Kimberly S.; Currier, Duane G.; Caufield, William; Wang, Yingzhe; Xie, Jia; Broniscer, Alberto; Wetmore, Cynthia; Upadhyaya, Santhosh A.; Qaddoumi, Ibrahim; Klimo, Paul; Boop, Frederick; Gajjar, Amar; Zhang, Jinghui; Orr, Brent A.; Robinson, Giles W.; Monje, Michelle; Freeman, Burgess B., III; Roussel, Martine F.; Northcott, Paul A.; Chen, Taosheng; Rankovic, Zoran; Wu, Gang; Chiang, Jason; Tinkle, Christopher L.; Shelat, Anang A.; Baker, Suzanne J. 分享 收藏
Characteristics of patients ≥10 years of age with diffuse intrinsic pontine glioma: a report from the International DIPG/DMG Registry Erker, Craig; Lane, Adam; Chaney, Brooklyn; Leary, Sarah; Minturn, Jane E.; Bartels, Ute; Packer, Roger J.; Dorris, Kathleen; Gottardo, Nicholas G.; Warren, Katherine E.; Broniscer, Alberto; Kieran, Mark W.; Zhu, Xiaoting; White, Peter; Dexheimer, Phillip J.; Black, Katie; Asher, Anthony; DeWire, Mariko; Hansford, Jordan R.; Gururangan, Sridharan; Nazarian, Javad; Ziegler, David S.; Sandler, Eric; Bartlett, Allison; Goldman, Stewart; Shih, Chie-Schin; Hassall, Tim; Dholaria, Hetal; Bandopadhayay, Pratiti; Samson, Yvan; Monje, Michelle; Fisher, Paul G.; Dodgshun, Andrew; Parkin, Sarah; Chintagumpala, Murali; Tsui, Karen; Gass, David; Larouche, Valerie; Broxson, Emmett; Lombardi, Mercedes Garcia; Wang, Stacie Shiqi; Ma, Jie; Hawkins, Cynthia; Hamideh, Dima; Wagner, Lars; Koschmann, Carl; Fuller, Christine; Drissi, Rachid; Jones, Blaise, V; Leach, James; Fouladi, Maryam 分享 收藏
TIGIT and PD-1 Immune Checkpoint Pathways Are Associated With Patient Outcome and Anti-Tumor Immunity in Glioblastoma Raphael, Itay; Kumar, Rajeev; McCarl, Lauren H.; Shoger, Karsen; Wang, Lin; Sandlesh, Poorva; Sneiderman, Chaim T.; Allen, Jordan; Zhai, Shuyan; Campagna, Marissa Lynn; Foster, Alexandra; Bruno, Tullia C.; Agnihotri, Sameer; Hu, Baoli; Castro, Brandyn A.; Lieberman, Frank S.; Broniscer, Alberto; Diaz, Aaron A.; Amankulor, Nduka M.; Rajasundaram, Dhivyaa; Pollack, Ian F.; Kohanbash, Gary 分享 收藏
The spectrum of rare central nervous system (CNS) tumors with EWSR1-non-ETS fusions: experience from three pediatric institutions with review of the literature 罕见的中枢神经系统 (CNS) 肿瘤与EWSR1-non-ETS融合的频谱: 来自三个儿科机构的经验与文献回顾 Lopez-Nunez, Oscar; Cafferata, Barbara; Santi, Mariarita; Ranganathan, Sarangarajan; Pearce, Thomas M.; Kulich, Scott M.; Bailey, Kelly M.; Broniscer, Alberto; Rossi, Sabrina; Zin, Angelica; Nasrallah, MacLean P.; Li, Marilyn M.; Zhong, Yiming; Miele, Evelina; Alaggio, Rita; Surrey, Lea F. 分享 收藏
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Phase II study of peginterferon alpha-2b for patients with unresectable or recurrent craniopharyngiomas: a Pediatric Brain Tumor Consortium report Goldman, Stewart; Pollack, Ian F.; Jakacki, Regina, I; Billups, Catherine A.; Poussaint, Tina Y.; Adesina, Adekunle M.; Panigrahy, Ashok; Parsons, Donald W.; Broniscer, Alberto; Robinson, Giles W.; Robison, Nathan J.; Partap, Sonia; Kilburn, Lindsay B.; Onar-Thomas, Arzu; Dunkel, Ira J.; Fouladi, Maryam 分享 收藏
Clinical, imaging, and molecular analysis of pediatric pontine tumors lacking characteristic imaging features of DIPG Chiang, Jason; Diaz, Alexander K.; Makepeace, Lydia; Li, Xiaoyu; Han, Yuanyuan; Li, Yimei; Klimo, Paul, Jr.; Boop, Frederick A.; Baker, Suzanne J.; Gajjar, Amar; Merchant, Thomas E.; Ellison, David W.; Broniscer, Alberto; Patay, Zoltan; Tinkle, Christopher L. 分享 收藏
Pediatric bithalamic gliomas have a distinct epigenetic signature and frequent EGFR exon 20 insertions resulting in potential sensitivity to targeted kinase inhibition Monday, Gourish; Lee, Julieann C.; Ravindranathan, Ajay; Villanueva-Meyer, Javier E.; Tran, Quynh T.; Allen, Sariah J.; Barreto, Jairo; Gupta, Rohit; Doo, Pamela; Van Ziftle, Jessica; Onodera, Courtney; Devine, Patrick; Grenert, James P.; Samuel, David; Li, Rong; Metrock, Laura K.; Jin, Lee-way; Antony, Reuben; Alashari, Mouied; Cheshier, Samuel; Whipple, Nicholas S.; Bruggers, Carol; Raffel, Corey; Gupta, Nalin; Kline, Cassie N.; Reddy, Alyssa; Banerjee, Anu; Hall, Matthew D.; Mehta, Minesh P.; Khatib, Ziad; Maher, Ossama M.; Brathwaite, Carole; Pekmezci, Melike; Phillips, Joanna J.; Bollen, Andrew W.; Tihan, Tarik; Lucas, John T., Jr.; Broniscer, Alberto; Berger, Mitchel S.; Perry, Arie; Orr, Brent A.; Solomon, David A. 分享 收藏
Defining Optimal Target Volumes of Conformal Radiation Therapy for Diffuse Intrinsic Pontine Glioma Tinkle, Christopher L.; Simone, Brittany; Chiang, Jason; Li, Xiaoyu; Campbell, Kristen; Han, Yuanyuan; Li, Yimei; Hover, Laura D.; Molitoris, Jason K.; Becksfort, Jared; Lucas, John T., Jr.; Patay, Zoltan; Baker, Suzanne J.; Broniscer, Alberto; Merchant, Thomas E. 分享 收藏
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