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Mertk promotes early microglial-mediated synaptic engulfment in Alzheimer's disease Mertk促进阿尔茨海默病中早期小胶质细胞介导的突触吞噬 Wu, Yifan; Fan, Yuanteng; Bao, Shisan; Song, Yinghao; Wang, Ruizhu; Wu, Jiaxuan; Liu, Xuan; Jin, Jingwen; Kong, Lingchen; Hou, Baohua; Liang, Peiyu; Chen, Taoxiang; Liu, Wanhong; Peng, Biwen; He, Fanggang; Zhou, Ying; Xu, Jian; Chen, Yun; Han, Song; Yin, Jun; He, Xiaohua 分享 收藏
5-Methylcytosine Analysis of miRNAs in Minimal Change Disease 微小病变疾病中miRNAs的5-甲基胞嘧啶分析 Zeng, Huiyi; Li, Dandan; Li, Yunyi; Yun, Chen; Zhang, Xinzhou; Gong, Wenyu; Xiao, Mengyun; Li, Haitao; Zeng, Zhipeng; Tan, Ruqi; Yang, Yishen; Luan, Shaodong; Dai, Yong; Yin, Lianghong; Tang, Donge 分享 收藏
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Efficacy and safety of simenafil in men with erectile dysfunction: a multicenter, randomized, double-blind, placebo-controlled, fixed dose, parallel group, phase 3 trial 西美那非在男性勃起功能障碍中的疗效与安全性：一项多中心、随机、双盲、安慰剂对照、固定剂量、平行组、III期试验 Yang, Yuzhuo; Zhang, Xiansheng; Jiang, Tao; Zhao, Lianming; Li, Fubiao; Yao, Wenliang; Deng, Junhong; Zhang, Xiangsheng; Yang, Jin; Ji, Zhigang; Tong, Zhigang; Chen, Yun; Wang, Zhen; Juan, Jiaxiang; Duan, Huaqing; Jiang, Hui 分享 收藏
Lemborexant ameliorates tau-mediated sleep loss and neurodegeneration in males in a mouse model of tauopathy Lemborexant 缓解了雄性小鼠tau蛋白病模型中的tau介导的睡眠丧失和神经退行性变。 Parhizkar, Samira; Bao, Xin; Chen, Wei; Rensing, Nicholas; Chen, Yun; Kipnis, Michal; Song, Sihui; Gent, Grace; Tycksen, Eric; Manis, Melissa; Lee, Choonghee; Serrano, Javier Remolina; Bosch, Megan E.; Franke, Emily; Yuede, Carla M.; Landsness, Eric C.; Wong, Michael; Holtzman, David M. 分享 收藏
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Apolipoprotein E secreted by astrocytes forms antiparallel dimers in discoidal lipoproteins Strickland, Michael R.; Rau, Michael J.; Summers, Brock; Basore, Katherine; Wulf II, John; Jiang, Hong; Chen, Yun; Ulrich, Jason D.; Randolph, Gwendalyn J.; Zhang, Rui; Fitzpatrick, James A. J.; Cashikar, Anil G.; Holtzman, David M. 分享 收藏
Microglia at sites of atrophy restrict the progression of retinal degeneration via galectin-3 and Trem2 萎缩部位的小胶质细胞通过galectin-3和Trem2限制视网膜变性的进展 Yu, Chen; Lad, Eleonora M.; Mathew, Rose; Shiraki, Nobuhiko; Littleton, Sejiro; Chen, Yun; Hou, Jinchao; Schlepckow, Kai; Degan, Simone; Chew, Lindsey; Amason, Joshua; Kalnitsky, Joan; Bowes Rickman, Catherine; Proia, Alan D.; Colonna, Marco; Haass, Christian; Saban, Daniel R. 分享 收藏
Detecting host responses to microbial stimulation using primary epithelial organoids Bornholdt, Jette; Muller, Christina V.; Nielsen, Maria Juul; Strickertsson, Jesper; Rago, Daria; Chen, Yun; Maciag, Grzegorz; Skov, Jonathan; Wellejus, Anja; Schweiger, Pawel J.; Hansen, Stine L.; Broholm, Christa; Gogenur, Ismail; Maimets, Martti; Sloth, Stine; Hendel, Jakob; Baker, Adam; Sandelin, Albin; Jensen, Kim B. 分享 收藏
Transcriptional and epigenomic profiling identifies YAP signaling as a key regulator of intestinal epithelium maturation Pikkupeura, Laura M.; Bressan, Raul B.; Guiu, Jordi; Chen, Yun; Maimets, Martti; Mayer, Daniela; Schweiger, Pawel J.; Hansen, Stine L.; Maciag, Grzegorz J.; Larsen, Hjalte L.; Lohmussaar, Kadi; Pedersen, Marianne Terndrup; Teves, Joji M. Yap; Bornholdt, Jette; Benes, Vladimir; Sandelin, Albin; Jensen, Kim B. 分享 收藏
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TREM2 inhibition triggers antitumor cell activity of myeloid cells in glioblastoma TREM2抑制触发胶质母细胞瘤中髓样细胞的抗肿瘤细胞活性 Sun, Rui; Han, Rowland; McCornack, Colin; Khan, Saad; Tabor, G. Travis; Chen, Yun; Hou, Jinchao; Jiang, Haowu; Schoch, Kathleen M.; Mao, Diane D.; Cleary, Ryan; Yang, Alicia; Liu, Qin; Luo, Jingqin; Petti, Allegra; Miller, Timothy M.; Ulrich, Jason D.; Holtzman, David M.; Kim, Albert H. 分享 收藏
Skin basal cell carcinomas assemble a pro-tumorigenic spatially organized and self-propagating Trem2+myeloid niche Haensel, Daniel; Daniel, Bence; Gaddam, Sadhana; Pan, Cory; Fabo, Tania; Bjelajac, Jeremy; Jussila, Anna R.; Gonzalez, Fernanda; Li, Nancy Yanzhe; Chen, Yun; Hou, JinChao; Patel, Tiffany; Aasi, Sumaira; Satpathy, Ansuman T.; Oro, Anthony E. 分享 收藏
Sleep deprivation exacerbates microglial reactivity and AP deposition in a TREM2-dependent manner in mice 睡眠剥夺以TREM2-dependent方式加剧小鼠小胶质细胞反应性和AP沉积 Parhizkar, Samira; Gent, Grace; Chen, Yun; Rensing, Nicholas; Gratuze, Maud; Strout, Gregory; Sviben, Sanja; Tycksen, Eric; Zhang, Qiang; Gilmore, Petra Erdmann; Sprung, Robert; Malone, Jim; Chen, Wei; Serrano, Javier Remolina; Bao, Xin; Lee, Choonghee; Wang, Chanung; Landsness, Eric; Fitzpatrick, James; Wong, Michael; Townsend, Reid; Colonna, Marco; Schmidt, Robert E.; Holtzman, David M. 分享 收藏
Transcriptomic atlas and interaction networks of brain cells in mouse CNS demyelination and remyelination Hou, Jinchao; Zhou, Yingyue; Cai, Zhangying; Terekhova, Marina; Swain, Amanda; Andhey, Prabhakar S.; Guimaraes, Rafaela M.; Antonova, Alina Ulezko; Qiu, Tian; Sviben, Sanja; Strout, Gregory; Fitzpatrick, James A. J.; Chen, Yun; Gilfillan, Susan; Kim, Do-Hyun; Van Dyken, Steven J.; Artyomov, Maxim N.; Colonna, Marco 分享 收藏
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