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A gut microbiota rheostat forecasts responsiveness to PD-L1 and VEGF blockade in mesothelioma Zhang, Min; Bzura, Aleksandra; Baitei, Essa Y.; Zhou, Zisen; Spicer, Jake B.; Poile, Charlotte; Rogel, Jan; Branson, Amy; King, Amy; Barber, Shaun; Kamata, Tamihiro; Dzialo, Joanna; Harber, James; Greystoke, Alastair; Nusrat, Nada; Faulkner, Daniel; Sun, Qianqian; Nolan, Luke; Hahne, Jens C.; Scotland, Molly; Walter, Harriet; Darlison, Liz; Morgan, Bruno; Bajaj, Amrita; Brookes, Cassandra; Hollox, Edward J.; Lubawska, Dominika; Jama, Maymun; Griffiths, Gareth; Nakas, Apostolos; Kutywayo, Kudzayi; Luo, Jin-Li; Klampatsa, Astero; Cooper, Andrea; Halder, Koirobi; Wells-Jordan, Peter; Zhou, Huiyu; Dudbridge, Frank; Thomas, Anne; Richards, Catherine Jane; Pritchard, Catrin; Yang, Hongji; Barer, Michael; Fennell, Dean A. 分享 收藏
An optimised patient-derived explant platform for breast cancer reflects clinical responses to chemotherapy and antibody-directed therapy Demetriou, Constantinos; Abid, Naila; Butterworth, Michael; Lezina, Larissa; Sandhu, Pavandeep; Howells, Lynne; Powley, Ian R.; Pringle, James H.; Sidat, Zahirah; Qassid, Omar; Purnell, Dave; Kaushik, Monika; Duckworth, Kaitlin; Hartshorn, Helen; Thomas, Anne; Shaw, Jacqui A.; MacFarlane, Marion; Pritchard, Catrin; Miles, Gareth J. 分享 收藏
BRAFV600E-mutated serrated colorectal neoplasia drives transcriptional activation of cholesterol metabolism Rzasa, Paulina; Whelan, Sarah; Farahmand, Pooyeh; Cai, Hong; Guterman, Inna; Palacios-Gallego, Raquel; Undru, Shanthi S.; Sandford, Lauren; Green, Caleb; Andreadi, Catherine; Mintseva, Maria; Parrott, Emma; Jin, Hong; Hey, Fiona; Giblett, Susan; Sylvius, Nicolas B.; Allcock, Natalie S.; Straatman-Iwanowska, Anna; Feuda, Roberto; Tufarelli, Cristina; Brown, Karen; Pritchard, Catrin; Rufini, Alessandro 分享 收藏
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Clonal architecture in mesothelioma is prognostic and shapes the tumour microenvironment (vol 12, 1751, 2021) Zhang, Min; Luo, Jin-Li; Sun, Qianqian; Harber, James; Dawson, Alan G.; Nakas, Apostolos; Busacca, Sara; Sharkey, Annabel J.; Waller, David; Sheaff, Michael T.; Richards, Cathy; Wells-Jordan, Peter; Gaba, Aarti; Poile, Charlotte; Baitei, Essa Y.; Bzura, Aleksandra; Dzialo, Joanna; Jama, Maymun; Le Quesne, John; Bajaj, Amrita; Martinson, Luke; Shaw, Jacqui A.; Pritchard, Catrin; Kamata, Tamihiro; Kuse, Nathaniel; Brannan, Lee; De Philip Zhang, Pan; Yang, Hongji; Griffiths, Gareth; Wilson, Gareth; Swanton, Charles; Dudbridge, Frank; Hollox, Edward J.; Fennell, Dean A. 分享 收藏
Clonal architecture in mesothelioma is prognostic and shapes the tumour microenvironment Zhang, Min; Luo, Jin-Li; Sun, Qianqian; Harber, James; Dawson, Alan G.; Nakas, Apostolos; Busacca, Sara; Sharkey, Annabel J.; Waller, David; Sheaff, Michael T.; Richards, Cathy; Wells-Jordan, Peter; Gaba, Aarti; Poile, Charlotte; Baitei, Essa Y.; Bzura, Aleksandra; Dzialo, Joanna; Jama, Maymun; Le Quesne, John; Bajaj, Amrita; Martison, Luke; Shaw, Jacqui A.; Pritchard, Catrin; Kamata, Tamihiro; Kuse, Nathaniel; Brannan, Lee; Zhang, Pan De Philip; Yang, Hongji; Griffiths, Gareth; Wilson, Gareth; Swanton, Charles; Dudbridge, Frank; Hollox, Edward J. 分享 收藏
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Digoxin treatment reactivates in vivo radioactive iodide uptake and correlates with favorable clinical outcome in non-medullary thyroid cancer Crezee, Thomas; Tesselaar, Marika H.; Nagarajah, James; Corver, Willem E.; Morreau, Johannes; Pritchard, Catrin; Kimura, Shioko; Kuiper, Josephina G.; van Engen-van Grunsven, Ilse; Smit, Jan W. A.; Netea-Maier, Romana T.; Plantinga, Theo S. 分享 收藏
Exploration of Matrix Effects in Laser Ablation Inductively Coupled Plasma Mass Spectrometry Imaging of Cisplatin-Treated Tumors Greenhalgh, Calum J.; Karekla, Ellie; Miles, Gareth J.; Powley, Ian R.; Costa, Catia; de Jesus, Janella; Bailey, Melanie J.; Pritchard, Catrin; MacFarlane, Marion; Pringle, J. Howard; Managh, Amy J. 分享 收藏
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Patient-derived explants (PDEs) as a powerful preclinical platform for anti-cancer drug and biomarker discovery Powley, Ian R.; Patel, Meeta; Miles, Gareth; Pringle, Howard; Howells, Lynne; Thomas, Anne; Kettleborough, Catherine; Bryans, Justin; Hammonds, Tim; MacFarlane, Marion; Pritchard, Catrin 分享 收藏
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Ex Vivo Explant Cultures of Non-Small Cell Lung Carcinoma Enable Evaluation of Primary Tumor Responses to Anticancer Therapy Karekla, Ellie; Liao, Wen-Jing; Sharp, Barry; Pugh, John; Reid, Helen; Le Quesne, John; Moore, David; Pritchard, Catrin; MacFarlane, Marion; Pringle, James Howard 分享 收藏
Cyp24a1 Attenuation Limits Progression of BrafV600E-Induced Papillary Thyroid Cancer Cells and Sensitizes Them to BRAFV600E Inhibitor PLX4720 Zou, Minjing; Baitei, Essa Y.; BinEssa, Huda A.; Al-Mohanna, Futwan A.; Parhar, Ranjit S.; St-Arnaud, Rene; Kimura, Shioko; Pritchard, Catrin; Alzahrani, Ali S.; Assiri, Abdullah M.; Meyer, Brian F.; Shi, Yufei 分享 收藏
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Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma Cammareri, Patrizia; Rose, Aidan M.; Vincent, David F.; Wang, Jun; Nagano, Ai; Libertini, Silvana; Ridgway, Rachel A.; Athineos, Dimitris; Coates, Philip J.; McHugh, Angela; Pourreyron, Celine; Dayal, Jasbani H. S.; Larsson, Jonas; Weidlich, Simone; Spender, Lindsay C.; Sapkota, Gopal P.; Purdie, Karin J.; Proby, Charlotte M.; Harwood, Catherine A.; Leigh, Irene M.; Clevers, Hans; Barker, Nick; Karlsson, Stefan; Pritchard, Catrin; Marais, Richard; Chelala, Claude; South, Andrew P.; Sansom, Owen J.; Inman, Gareth J. 分享 收藏