Jean‐Yves Masson - Publications, H-index & Citations

Jean‐Yves Masson

Leiden University

61H指数

290论文数

1.3W被引数

收录论文 136

发表时间

ZIPPing the gaps: A new class of zinc finger proteins orchestrates the DNA damage response ZIPPing the gaps: 一类新的锌指蛋白调控DNA损伤应答

DNA Repair

IF2.7

2026-09-14

PREAI

Louis Nonfoux; Jean-Philippe Gagné; Bong Gu Kang; Sung-Ung Kang; Michael J. Hendzel; Ted M. Dawson; Valina L. Dawson; Jean-Yves Masson; Guy G. Poirier

PARP1 and PARylation facilitate transcription-coupled DNA repair by stabilizing the CSB-RNAPII complex PARP1和PARylation通过稳定CSB-RNAPII复合物来促进转录偶联的DNA修复。

NUCLEIC ACIDS RESEARCH

IF13.1

2025-12-11

OAAI

Robu, Mihaela; Shah, Rashmi G.; Van den heuvel, Diana; Coulombe, Yan; Bazin, Marc; Van der woude, Melanie; Kragten, Angela; Lans, Hannes; Pascal, John M.; Masson, Jean-Yves; Luijsterburg, Martijn S.; Shah, Girish M.

PALB2 and 53BP1 govern post-resection homologous recombination DNA repair PALB2和53BP1调控切除后的同源重组DNA修复

Molecular Cell

IF16.6

2025-10-15

PREAI

Yifan Wang; Yan Coulombe; Wei-Ting Yueh; Gregory D. Conway; Larissa Milano; David J. Glass; Mélissa Thomas; Amélie Rodrigue; Joseph Nacson; Dongbo Lu; Andrea J. Bernhardy; Robert G. Betsch; Alyssa I. Russo; Gamal A. Elfar; Kathy Q. Cai; Joseph R. Testa; Mark Andrake; Roland Dunbrack; Gaorav P. Gupta; Bing Xia; Eloise Dray; Jean-Yves Masson; Neil Johnson

Specifications of the ACMG/AMP variant curation guidelines for the analysis of germline PALB2 sequence variants ACMG/AMP变异整理指南中关于体细胞PALB2序列变异分析的规定

american journal of human genetics

IF0

2025-09-17

OAAI

Marcy E. Richardson; Megan F.H. Bishop; Megan A. Holdren; Miguel de la Hoya; Amanda B. Spurdle; Sean V. Tavtigian; Terra Brannan; Colin C. Young; Lauren Zec; Susan Hiraki; Clare Turnbull; Marc Tischkowitz; Kara A. Bernstein; Jean-Yves Masson; Shannon M. McNulty; Tina Pesaran; Alvaro N. Monteiro; Logan C. Walker; William D. Foulkes; Fergus J. Couch

Pathogenic variants in MAEA disrupt DNA replication fork stability and are associated with developmental abnormalities in humans MAEA基因中的致病性变异会破坏DNA复制叉的稳定性，并与人类发育异常相关。

Science Advances

IF12.5

2025-08-29

OAAI

Elham Zeinali; Fatemeh Mashayekhi; Rabih Abou Farraj; Talah Hasanni; Marie-Christine Caron; Yan Coulombe; Amira Fitieh; J. N. Mark Glover; Jean-Yves Masson; Ismail Hassan Ismail

Ubiquitination of the histone variant mH2A1.2 prevents toxic RAD18 accumulation at a subset of genomic loci upon replication stress 组蛋白变体mH2A1.2的泛素化在复制应激时阻止了RAD18在部分基因组位点的毒性积聚

Molecular Cell

IF16.6

2025-08-13

PREAI

Maxime Galloy; Andréanne Blondeau; Élodie Vion; Daein Kim; Collin A. Bakker; Vincent Gaggioli; Mélissa Thomas; Élise G. Lavoie; Isabelle Marois; Alberto David Delgado Monterroso; Jean-Yves Masson; Nitika Taneja; Kyle M. Miller; Alexandre Maréchal; Amélie Fradet-Turcotte

PALB2 and 53BP1 govern post-resection homologous recombination DNA repair PALB2和53BP1调控切除后的同源重组DNA修复

Molecular Cell

IF16.6

2025-07-31

PREAI

HMCES corrupts replication fork stability during base excision repair in homologous recombination-deficient cells HMCES 在同源重组缺陷细胞中破坏碱基切除修复期间的复制叉稳定性

SCIENCE ADVANCES

IF12.5

2025-03-28

PREAI

Pena-Gomez, Maria Jose; Rodriguez-Martin, Yaiza; del Rio Oliva, Marta; Wijesekara Hanthi, Yodhara; Berrada, Sara; Freire, Raimundo; Masson, Jean Yves; Reyes, Jose Carlos; Costanzo, Vincenzo; Rosado, Ivan V.

PNKP safeguards stalled replication forks from nuclease-dependent degradation stress

CELL REPORTS

IF6.9

2024-12-01

OAAI

Mashayekhi, Fatemeh; Ganje, Cassandra; Caron, Marie-Christine; Heyza, Joshua R.; Gao, Yuandi; Zeinali, Elham; Fanta, Mesfin; Li, Lei; Ali, Jana; Mersaoui, Sofiane Yacine; Schmidt, Jens C.; Godbout, Roseline; Masson, Jean-Yves; Weinfeld, Michael; Ismail, Ismail Hassan

Inhibition of nicotinamide adenine dinucleotide (NAD) production is a potent therapeutic strategy to inactivate homologous recombination in cancer cells

MOLECULAR CANCER THERAPEUTICS

IF5.5

2024-06-10

PREAI

Sheida, Sadaf Valeh; Peterlini, Thibaut; Thomas, Melissa; Poirier, Guy; Masson, Jean-Yves

Cell-type-specific CAG repeat expansions and toxicity of mutant Huntingtin in human striatum and cerebellum

NATURE GENETICS

IF31.8

2024-01-30

OAAI

Matlik, Kert; Baffuto, Matthew; Kus, Laura; Deshmukh, Amit Laxmikant; Davis, David A.; Paul, Matthew R.; Carroll, Thomas S.; Caron, Marie-Christine; Masson, Jean-Yves; Pearson, Christopher E.; Heintz, Nathaniel

The protein phosphatase EYA4 promotes homologous recombination (HR) through dephosphorylation of tyrosine 315 on RAD51 蛋白磷酸酶EYA4通过RAD51上酪氨酸315的去磷酸化促进同源重组 (HR)

NUCLEIC ACIDS RESEARCH

IF13.1

2023-12-12

OAAI

de la Pena Avalos, Barbara; Paquet, Nicolas; Tropee, Romain; Coulombe, Yan; Palacios, Hannah; Leung, Justin W.; Masson, Jean-Yves; Duijf, Pascal H. G.; Dray, Eloise

Human RAD52 stimulates the RAD51-mediated homology search

LIFE SCIENCE ALLIANCE

IF2.9

2023-12-11

OAAI

Muhammad, Ali Akbar; Basto, Clara; Peterlini, Thibaut; Guirouilh-Barbat, Jos ee; Thomas, Melissa; Veaute, Xavier; Busso, Didier; Lopez, Bernard; Mazon, Gerard; Le Cam, Eric; Masson, Jean-Yves; Dupaigne, Pauline

ZNF432 stimulates PARylation and inhibits DNA resection to balance PARPi sensitivity and resistance

NUCLEIC ACIDS RESEARCH

IF13.1

2023-10-12

OAAI

O'Sullivan, Julia; Kothari, Charu; Caron, Marie-Christine; Gagne, Jean-Philippe; Jin, Zhigang; Nonfoux, Louis; Beneyton, Adele; Coulombe, Yan; Thomas, Melissa; Atalay, Nurgul; Meng, X. Wei; Milano, Larissa; Jean, Dominique; Boisvert, Francois-Michel; Kaufmann, Scott H.; Hendzel, Michael J.; Masson, Jean-Yves; Poirier, Guy G.

RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells XRN2的RNF8泛素化促进R环解析并抑制BRCA1突变细胞中的基因组不稳定性

NUCLEIC ACIDS RESEARCH

IF13.1

2023-09-11

OAAI

Krishnan, Rehna; Lapierre, Mariah; Gautreau, Brandon; Nixon, Kevin C. J.; El Ghamrasni, Samah; Patel, Parasvi S.; Hao, Jun; Yerlici, V. Talya; Guturi, Kiran Kumar Naidu; St-Germain, Jonathan; Mateo, Francesca; Saad, Amine; Algouneh, Arash; Earnshaw, Rebecca; Shili, Duan; Seitova, Alma; Miller, Joshua; Khosraviani, Negin; Penn, Adam; Ho, Brandon; Sanchez, Otto; Hande, M. Prakash; Masson, Jean-Yves; Brown, Grant W.; Alaoui-Jamali, Moulay; Reynolds, John J.; Arrowsmith, Cheryl; Raught, Brian; Pujana, Miguel A.; Mekhail, Karim; Stewart, Grant S.; Hakem, Anne; Hakem, Razqallah

The dynamic process of covalent and non-covalent PARylation in the maintenance of genome integrity: a focus on PARP inhibitors

NAR CANCER

IF3.2

2023-08-21

OAAI

Beneyton, Adele; Nonfoux, Louis; Gagne, Jean-Philippe; Rodrigue, Amelie; Kothari, Charu; Atalay, Nurgul; Hendzel, Michael J.; Poirier, Guy G.; Masson, Jean-Yves

FIRRM cooperates with FIGNL1 to promote RAD51 disassembly during DNA repair

SCIENCE ADVANCES

IF12.5

2023-08-11

OAAI

Pinedo-Carpio, Edgar; Dessapt, Julien; Beneyton, Adele; Sacre, Lauralicia; Berube, Marie-Anne; Villot, Romain; Lavoie, Elise G.; Coulombe, Yan; Blondeau, Andreanne; Boulais, Jonathan; Malina, Abba; Luo, Vincent M.; Lazaratos, Anna-Maria; Cote, Jean-Francois; Mallette, Frederick A.; Guarne, Alba; Masson, Jean-Yves; Fradet-Turcotte, Amelie; Orthwein, Alexandre

FANCD2 and RAD51 recombinase directly inhibit DNA2 nuclease at stalled replication forks and FANCD2 acts as a novel RAD51 mediator in strand exchange to promote genome stability

NUCLEIC ACIDS RESEARCH

IF13.1

2023-08-01

OAAI

Liu, Wenpeng; Polaczek, Piotr; Roubal, Ivan; Meng, Yuan; Choe, Won-chae; Caron, Marie-Christine; Sedgeman, Carl A.; Xi, Yu; Liu, Changwei; Wu, Qiong; Zheng, Li; Masson, Jean-Yves; Shen, Binghui; Campbell, Judith L.

Functional and Clinical Characterization of Variants of Uncertain Significance Identifies a Hotspot for Inactivating Missense Variants in RAD51C 意义不确定的变体的功能和临床表征确定了RAD51C中失活错义变体的热点

CANCER RESEARCH

IF16.6

2023-05-30

OAAI

Hu, Chunling; Nagaraj, Anil Belur; Shimelis, Hermela; Montalban, Gemma; Lee, Kun Y.; Huang, Huaizhi; Lumby, Carolyn A.; Na, Jie; Susswein, Lisa R.; Roberts, Maegan E.; Marshall, Megan L.; Hiraki, Susan; LaDuca, Holly; Chao, Elizabeth; Yussuf, Amal; Pesaran, Tina; Neuhausen, Susan L.; Haiman, Christopher A.; Kraft, Peter; Lindstrom, Sara; Palmer, Julie R.; Teras, Lauren R.; Vachon, Celine M.; Yao, Song; Ong, Irene; Nathanson, Katherine L.; Weitzel, Jeffrey N.; Boddicker, Nicholas; Gnanaolivu, Rohan; Polley, Eric C.; Mer, Georges; Cui, Gaofeng; Karam, Rachid; Richardson, Marcy E.; Domchek, Susan M.; Yadav, Siddhartha; Hruska, Kathleen S.; Dolinsky, Jill; Weroha, S. John; Hart, Steven N.; Simard, Jacques; Masson, Jean Yves; Pang, Yuan-Ping; Couch, Fergus J.

Variants in ATRIP are associated with breast cancer susceptibility in the Polish population and UK Biobank

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2023-04-01

OAAI

Cybulski, Cezary; Zamani, Neda; Kluzniak, Wojciech; Milano, Larissa; Wokolorczyk, Dominika; Stempa, Klaudia; Rudnicka, Helena; Zhang, Shiyu; Zadeh, Maryam; Huzarski, Tomasz; Jakubowska, Anna; Debniak, Tadeusz; Lener, Marcin; Szwiec, Marek; Domagala, Pawel; Samani, Amir Abbas; Narod, Steven; Gronwald, Jacek; Masson, Jean-Yves; Lubnski, Jan; Akbari, Mohammad R.

研究方向