David W. Taylor - Publications, H-index & Citations

David W. Taylor

University of Texas at Austin

45H指数

219论文数

9.3K被引数

收录论文 70

发表时间

A cryptic binding pocket regulates the metal-dependent activity of Cas9 一个隐藏的结合口袋调控Cas9的金属依赖性活性

Nature Communications

IF15.7

2026-10-09

OAAI

Mohd Ahsan; Alexa L. Knight; Aakash Saha; Delisa Ramos; Isabel Strohkendl; Erin Skeens; Madeline S. West; Jinping Luo; Charlotte S. Dresser; David W. Taylor; George P. Lisi; Giulia Palermo

Architecture of a DNA-guided Cas12a DNA引导的Cas12a结构

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2026-09-09

OAAI

Rodrigo Fregoso Ocampo; Carlos Orosco; Boyu Huang; Madeline S. West; Bay Parker; Piyush K. Jain; David W. Taylor

Molecular mechanisms and biotechnology applications of CRISPR–Cas12a CRISPR–Cas12a的分子机制与生物技术应用

Nature Reviews Molecular Cell Biology

IF90.2

2026-04-27

PREAI

Aakash Saha; Rodrigo Fregoso Ocampo; Jacquelyn T. Wright; David W. Taylor; Giulia Palermo

Comparative characterization of Cas12f orthologs reveals mechanistic features underlying enhanced genome editing efficiency Cas12f直系同源物的比较表征揭示了增强基因组编辑效率的机制特征

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2026-04-13

OAAI

Kaoling Guan; Rodrigo Fregoso Ocampo; Paula B. Matheus Carnevali; Cindy J. Castelle; Liliana Gonzalez-Osorio; Dominic T. Castanzo; Nicole C. Thomas; Molly Brothers; Tyler L. Dangerfield; Matthew M. Hooper; Madeline S. West; Nathan M. Appleby; Isabella Krudop; Rebecca C. Lamothe; Daniela S. Aliaga Goltsman; Lisa M. Alexander; Cristina N. Butterfield; Kenneth A. Johnson; Christopher T. Brown; David W. Taylor

Kiwa is a membrane-embedded defense supercomplex activated at phage attachment sites Kiwa是一种嵌入膜中的防御超复合物，在噬菌体附着位点被激活。

Cell

IF42.5

2025-07-28

OAAI

Zhiying Zhang; Thomas C. Todeschini; Yi Wu; Roman Kogay; Ameena Naji; Joaquin Cardenas Rodriguez; Rupavidhya Mondi; Daniel Kaganovich; David W. Taylor; Jack P.K. Bravo; Marianna Teplova; Triana Amen; Eugene V. Koonin; Dinshaw J. Patel; Franklin L. Nobrega

The assembly factor Reh1 is released from the ribosome during its initial round of translation 组装因子Reh1在其翻译初始轮次期间从核糖体释放。

NATURE COMMUNICATIONS

IF15.7

2025-02-03

OAAI

Musalgaonkar, Sharmishtha; Yelland, James N.; Chitale, Ruta; Rao, Shilpa; Ozadam, Hakan; Taylor, David W.; Cenik, Can; Johnson, Arlen W.

DNA targeting by compact Cas9d and its resurrected ancestor 紧凑型Cas9d的DNA靶向作用及其复活祖先

NATURE COMMUNICATIONS

IF15.7

2025-01-07

OAAI

Ocampo, Rodrigo Fregoso; Bravo, Jack P. K.; Dangerfield, Tyler L.; Nocedal, Isabel; Jirde, Samatar A.; Alexander, Lisa M.; Thomas, Nicole C.; Das, Anjali; Nielson, Sarah; Johnson, Kenneth A.; Brown, Christopher T.; Butterfield, Cristina N.; Goltsman, Daniela S. A.; Taylor, David W.

Cas12a domain flexibility guides R-loop formation and forces RuvC resetting

MOLECULAR CELL

IF16.6

2024-07-01

OAAI

Strohkendl, Isabel; Saha, Aakash; Moy, Catherine; Nguyen, Alexander-Hoi; Ahsan, Mohd; Russell, Rick; Palermo, Giulia; Taylor, David W.

Lipid droplets as substrates for protein phase separation

BIOPHYSICAL JOURNAL

IF3.1

2024-06-01

OAAI

Kamatar, Advika; Bravo, Jack P. K.; Yuan, Feng; Wang, Liping; Lafer, Eileen M.; Taylor, David W.; Stachowiak, Jeanne C.; Parekh, Sapun H.

Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9

NATURE COMMUNICATIONS

IF15.7

2024-04-30

OAAI

Hibshman, Grace N.; Bravo, Jack P. K.; Hooper, Matthew M.; Dangerfield, Tyler L.; Zhang, Hongshan; Finkelstein, Ilya J.; Johnson, Kenneth A.; Taylor, David W.

RNA targeting and cleavage by the type III-Dv CRISPR effector complex

NATURE COMMUNICATIONS

IF15.7

2024-04-18

OAAI

Schwartz, Evan A.; Bravo, Jack P. K.; Ahsan, Mohd; Macias, Luis A.; Mccafferty, Caitlyn L.; Dangerfield, Tyler L.; Walker, Jada N.; Brodbelt, Jennifer S.; Palermo, Giulia; Fineran, Peter C.; Fagerlund, Robert D.; Taylor, David W.

Structural biology of an organ

CELL REPORTS

IF6.9

2023-06-01

OAAI

Taylor, David W.

Does AlphaFold2 model proteins' intracellular conformations? An experimental test using cross-linking mass spectrometry of endogenous ciliary proteins AlphaFold2是否模拟蛋白质的细胞内构象？使用内源性睫状蛋白的交联质谱进行的实验测试

COMMUNICATIONS BIOLOGY

IF5.1

2023-04-15

OAAI

McCafferty, Caitlyn L.; Pennington, Erin L.; Papoulas, Ophelia; Taylor, David W.; Marcotte, Edward M.

Structural snapshots of R-loop formation by a type I-C CRISPR Cascade

MOLECULAR CELL

IF16.6

2023-03-01

OAAI

O'Brien, Roisin E.; Bravo, Jack P. K.; Ramos, Delisa; Hibshman, Grace N.; Wright, Jacquelyn T.; Taylor, David W.

A single 2'-O-methylation of ribosomal RNA gates assembly of a functional ribosome

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2022-12-19

OAAI

Yelland, James N.; Bravo, Jack P. K.; Black, Joshua J.; Taylor, David W.; Johnson, Arlen W.

Constructing next-generation CRISPR-Cas tools from structural blueprints 从结构蓝图构建下一代crispr-cas工具

CURRENT OPINION IN BIOTECHNOLOGY

IF7

2022-12-01

PREAI

Bravo, Jack P. K.; Hibshman, Grace N.; Taylor, David W.

Integrative modeling reveals the molecular architecture of the intraflagellar transport A (IFT-A) complex 整合模型揭示了鞭毛内运输A (ift-a) 复合物的分子结构

ELIFE

IF0

2022-11-08

OAAI

McCafferty, Caitlyn L.; Papoulas, Ophelia; Jordan, Mareike A.; Hoogerbrugge, Gabriel; Nichols, Candice; Pigino, Gaia; Taylor, David W.; Wallingford, John B.; Marcotte, Edward M.

The protein organization of a red blood cell 红细胞的蛋白质组织

CELL REPORTS

IF6.9

2022-07-01

OAAI

Sae-Lee, Wisath; McCafferty, Caitlyn L.; Verbeke, Eric J.; Havugimana, Pierre C.; Papoulas, Ophelia; McWhite, Claire D.; Houser, John R.; Vanuytsel, Kim; Murphy, George J.; Drew, Kevin; Emili, Andrew; Taylor, David W.; Marcotte, Edward M.

Structural basis for broad anti-phage immunity by DISARM

NATURE COMMUNICATIONS

IF15.7

2022-05-27

OAAI

Bravo, Jack P. K.; Aparicio-Maldonado, Cristian; Nobrega, Franklin L.; Brouns, Stan J. J.; Taylor, David W.

Structural rearrangements allow nucleic acid discrimination by type I-D Cascade

NATURE COMMUNICATIONS

IF15.7

2022-05-20

OAAI

Schwartz, Evan A.; McBride, Tess M.; Bravo, Jack P. K.; Wrapp, Daniel; Fineran, Peter C.; Fagerlund, Robert D.; Taylor, David W.

研究方向