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Using gene-environment interactions to explore pathways for colorectal cancer risk 使用基因-环境相互作用探索结直肠癌风险的途径 Bouras, Emmanouil; Yu, Ren; Kim, Andre E.; Markozannes, Georgios; Murphy, Neil; Albanes, Demetrius; Anderson, Laura N.; Barry, Elizabeth L.; Berndt, Sonja I.; Bishop, D. Timothy; Brenner, Hermann; Burnett-Hartman, Andrea; Campbell, Peter T.; Carreras-Torres, Robert; Chan, Andrew T.; Cheng, Iona; Devall, Matthew A.; Diez-Obrero, Virginia; Dimou, Niki; Drew, David A.; Gruber, Stephen B.; Gsur, Andrea; Hoffmeister, Michael; Hsu, Li; Huyghe, Jeroen R.; Kawaguchi, Eric; Keku, Temitope O.; Kundaje, Anshul; Kury, Sebastien; Le Marchand, Loic; Lewinger, Juan Pablo; Li, Li; Lynch, Brigid M.; Moreno, Victor; Morrison, John L.; Newton, Christina C.; Obon-Santacana, Mireia; Palmer, Julie R.; Papadimitriou, Nikos; Pellatt, Andrew J.; Peoples, Anita R.; Pharoah, Paul D. P.; Platz, Elizabeth A.; Qu, Conghui; Ruiz-Narvaez, Edward; Mendez, Joel Sanchez; Schoen, Robert E.; Stern, Mariana C.; Thomas, Claire E.; Tian, Yu; Um, Caroline Y.; Visvanathan, Kala; Vodicka, Pavel; Vymetalkova, Veronika; White, Emily; Wolk, Alicja; Woods, Michael O.; Wu, Anna H.; Gunter, Marc J.; Gauderman, W. James; Peters, Ulrike; Evangelou, Marina; Tsilidis, Konstantinos K. 分享 收藏
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A comprehensive study of genetic regulation and disease associations of plasma circulatory microRNAs using population-level data 使用人群水平数据对血浆循环microRNAs的遗传调控和疾病关联进行综合研究 Mustafa, Rima; Mens, Michelle M. J.; van Hilten, Arno; Huang, Jian; Roshchupkin, Gennady; Huan, Tianxiao; Broer, Linda; van Meurs, Joyce B. J.; Elliott, Paul; Levy, Daniel; Ikram, M. Arfan; Evangelou, Marina; Dehghan, Abbas; Ghanbari, Mohsen 分享 收藏
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A Genetic Locus within the FMN1/GREM1 Gene Region Interacts with Body Mass Index in Colorectal Cancer Risk Aglago, Elom K.; Kim, Andre; Lin, Yi; Qu, Conghui; Evangelou, Marina; Ren, Yu; Morrison, John; Albanes, Demetrius; Arndt, Volker; Barry, Elizabeth L.; Baurley, James W.; Berndt, Sonja, I; Bien, Stephanie A.; Bishop, D. Timothy; Bouras, Emmanouil; Brenner, Hermann; Buchanan, Daniel D.; Budiarto, Ari; Carreras-Torres, Robert; Casey, Graham; Cenggoro, Tjeng Wawan; Chen, Andrew T.; Chang-Claude, Jenny; Chen, Xuechen; Conti, David, V; Devall, Matthew; Diez-Obrero, Virginia; Dimou, Niki; Drew, David; Figueiredo, Jane C.; Gallinger, Steven; Giles, Graham G.; Gruber, Stephen B.; Gsur, Andrea; Gunter, Marc J.; Hampel, Heather; Harlid, Sophia; Hidaka, Akihisa; Harrison, Tabitha A.; Hoffmeister, Michael; Huyghe, Jeroen R.; Jenkins, Mark A.; Jordahl, Kristina; Joshi, Amit D.; Kawaguchi, Eric S.; Keku, Temitope O.; Kundaje, Anshul; Larsson, Susanna C.; Le Marchand, Loic; Lewinger, Juan Pablo; Li, Li; Lynch, Brigid M.; Mahesworo, Bharuno; Mandic, Marko; Obon-Santacana, Mireia; Morento, Victor; Murphy, Neil; Men, Hongmei; Nassir, Rami; Newcomb, Polly A.; Ogino, Shuji; Ose, Jennifer; Pai, Rish K.; Palmer, Julie R.; Papadimitriou, Nikos; Pardamean, Bens; Peoples, Anita R.; Platz, Elizabeth A.; Potter, John D.; Prentice, Ross L.; Rennert, Gad; Ruiz-Narvaez, Edward; Sakoda, Lori C.; Scacheri, Peter C.; Schmit, Stephanie L.; Schoen, Robert E.; Shcherbina, Anna; Slattery, Martha L.; Stern, Mariana C.; Su, Yu-Ru; Tangen, Catherine M.; Thibodeau, Stephen N.; Thomas, Duncan C.; Tian, Yu; Ulrich, Cornelia M.; van Duijnhoven, Franzel J. B.; Van Guelpen, Bethany; Visvanathan, Kala; Vodicka, Pavel; Wang, Jun; White, Emily; Wolk, Alicja; Woods, Michael O.; Wu, Anna H.; Zemlianskaia, Natalia; Hsu, Li; Gauderman, W. James; Peters, Ulrike; Tsilidis, Konstantinos K.; Campbell, Peter T. 分享 收藏
Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling 较高的促甲状腺激素会导致不利的血脂状况和较高的心血管疾病风险: 来自多队列孟德尔随机化和代谢组学分析的证据 van Vliet, Nicolien A.; Bos, Maxime M.; Thesing, Carisha S.; Chaker, Layal; Pietzner, Maik; Houtman, Evelyn; Neville, Matt J.; Li-Gao, Ruifang; Trompet, Stella; Mustafa, Rima; Ahmadizar, Fariba; Beekman, Marian; Bot, Mariska; Budde, Kathrin; Christodoulides, Constantinos; Dehghan, Abbas; Delles, Christian; Elliott, Paul; Evangelou, Marina; Gao, He; Ghanbari, Mohsen; van Herwaarden, Antonius E.; Ikram, M. Arfan; Jaeger, Martin; Jukema, J. Wouter; Karaman, Ibrahim; Karpe, Fredrik; Kloppenburg, Margreet; Meessen, Jennifer M. T. A.; Meulenbelt, Ingrid; Milaneschi, Yuri; Mooijaart, Simon P.; Mook-Kanamori, Dennis O.; Netea, Mihai G.; Netea-Maier, Romana T.; Peeters, Robin P.; Penninx, Brenda W. J. H.; Sattar, Naveed; Slagboom, P. Eline; Suchiman, H. Eka D.; Volzke, Henry; Willems van Dijk, Ko; Noordam, Raymond; van Heemst, Diana 分享 收藏
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Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (vol 50, pg 1412, 2018) 超过100万人的遗传分析确定了535个与血压性状相关的新基因座 (第50卷，1412页，2018) Evangelou, Evangelos; Warren, Helen R.; Mosen-Ansorena, David; Mifsud, Borbala; Pazoki, Raha; Gao, He; Ntritsos, Georgios; Dimou, Niki; Cabrera, Claudia P.; Karaman, Ibrahim; Fu Liang Ng; Evangelou, Marina; Witkowska, Katarzyna; Tzanis, Evan; Hellwege, Jacklyn N.; Giri, Ayush; Edwards, Digna R. Velez; Sun, Yan V.; Cho, Kelly; Gaziano, J. Michael; Wilson, Peter W. F.; Tsao, Philip S.; Kovesdy, Csaba P.; Esko, Tonu; Magi, Reedik; Milani, Lili; Almgren, Peter; Boutin, Thibaud; Debette, Stephanie; Ding, Jun; Giulianini, Franco; Holliday, Elizabeth G.; Jackson, Anne U.; Li-Gao, Ruifang; Lin, Wei-Yu; Luan, Jian'an; Mangino, Massimo; Oldmeadow, Christopher; Prins, Bram Peter; Qian, Yong; Sargurupremraj, Muralidharan; Shah, Nabi; Surendran, Praveen; Theriault, Sebastien; Verweij, Niek; Willems, Sara M.; Zhao, Jing-Hua; Amouyel, Philippe; Connell, John; de Mutsert, Renee; Doney, Alex S. F.; Farrall, Martin; Menni, Cristina; Morris, Andrew D.; Noordam, Raymond; Pare, Guillaume; Poulter, Neil R.; Shields, Denis C.; Stanton, Alice; Thom, Simon; Abecasis, Goncalo; Amin, Najaf; Arking, Dan E.; Ayers, Kristin L.; Barbieri, Caterina M.; Batini, Chiara; Bis, Joshua C.; Blake, Tineka; Bochud, Murielle; Boehnke, Michael; Boerwinkle, Eric; Boomsma, Dorret I.; Bottinger, Erwin P.; Braund, Peter S.; Brumat, Marco; Campbell, Archie; Campbell, Harry; Chakravarti, Aravinda; Chambers, John C.; Chauhan, Ganesh; Ciullo, Marina; Cocca, Massimiliano; Collins, Francis; Cordell, Heather J.; Davies, Gail; de Borst, Martin H.; de Geus, Eco J.; Deary, Ian J.; Deelen, Joris; Del Greco, Fabiola M.; Demirkale, Cumhur Yusuf; Dorr, Marcus; Ehret, Georg B.; Elosua, Roberto; Enroth, Stefan; Erzurumluoglu, A. Mesut; Ferreira, Teresa; Franberg, Mattias; Franco, Oscar H.; Gandin, Ilaria; Gasparini, Paolo; Giedraitis, Vilmantas; Gieger, Christian; Girotto, Giorgia; Goel, Anuj; Gow, Alan J.; Gudnason, Vilmundur; Guo, Xiuqing; Gyllensten, Ulf; Hamsten, Anders; Harris, Tamara B.; Harris, Sarah E.; Hartman, Catharina A.; Havulinna, Aki S.; Hicks, Andrew A.; Hofer, Edith; Hofman, Albert; Hottenga, Jouke-Jan; Huffman, Jennifer E.; Hwang, Shih-Jen; Ingelsson, Erik; James, Alan; Jansen, Rick; Jarvelin, Marjo-Riitta; Joehanes, Roby; Johansson, Asa; Johnson, Andrew D.; Joshi, Peter K.; Jousilahti, Pekka; Jukema, J. Wouter; Jula, Antti; Kahonen, Mika; Kathiresan, Sekar; Keavney, Bernard D.; Khaw, Kay-Tee; Knekt, Paul; Knight, Joanne; Kolcic, Ivana; Kooner, Jaspal S.; Koskinen, Seppo; Kristiansson, Kati; Kutalik, Zoltan; Laan, Maris; Larson, Marty; Launer, Lenore J.; Lehne, Benjamin; Lehtimaki, Terho; Liewald, David C. M.; Lin, Li; Lind, Lars; Lindgren, Cecilia M.; Liu, YongMei; Loos, Ruth J. F.; Lopez, Lorna M.; Lu, Yingchang; Lyytikainen, Leo-Pekka; Mahajan, Anubha; Mamasoula, Chrysovalanto; Marrugat, Jaume; Marten, Jonathan; Milaneschi, Yuri; Morgan, Anna; Morris, Andrew P.; Morrison, Alanna C.; Munson, Peter J.; Nalls, Mike A.; Nandakumar, Priyanka; Nelson, Christopher P.; Niiranen, Teemu; Nolte, Ilja M.; Nutile, Teresa; Oldehinkel, Albertine J.; Oostra, Ben A.; O'Reilly, Paul F.; Org, Elin; Padmanabhan, Sandosh; Palmas, Walter; Palotie, Aarno; Pattie, Alison; Penninx, Brenda W. J. H.; Perola, Markus; Peters, Annette; Polasek, Ozren; Pramstaller, Peter P.; Quang Tri Nguyen; Raitakari, Olli T.; Ren, Meixia; Rettig, Rainer; Rice, Kenneth; Ridker, Paul M.; Ried, Janina S.; Riese, Harriette; Ripatti, Samuli; Robino, Antonietta; Rose, Lynda M.; Rotter, Jerome I.; Rudan, Igor; Ruggiero, Daniela; Saba, Yasaman; Sala, Cinzia F.; Salomaa, Veikko; Samani, Nilesh J.; Sarin, Antti-Pekka; Schmidt, Reinhold; Schmidt, Helena; Shrine, Nick; Siscovick, David; Smith, Albert V.; Snieder, Harold; Sober, Siim; Sorice, Rossella; Starr, John M.; Stott, David J.; Strachan, David P.; Strawbridge, Rona J.; Sundstrom, Johan; Swertz, Morris A.; Taylor, Kent D.; Teumer, Alexander; Tobin, Martin D.; Tomaszewski, Maciej; Toniolo, Daniela; Traglia, Michela; Trompet, Stella; Tuomilehto, Jaakko; Tzourio, Christophe; Uitterlinden, Andre G.; Vaez, Ahmad; van der Most, Peter J.; van Duijn, Cornelia M.; Vergnaud, Anne-Claire; Verwoert, Germaine C.; Vitart, Veronique; Volker, Uwe; Vollenweider, Peter; Vuckovic, Dragana; Watkins, Hugh; Wild, Sarah H.; Willemsen, Gonneke; Wilson, James F.; Wright, Alan F.; Yao, Jie; Zemunik, Tatijana; Zhang, Weihua; Attia, John R.; Butterworth, Adam S.; Chasman, Daniel I.; Conen, David; Cucca, Francesco; Danesh, John; Hayward, Caroline; Howson, Joanna M. M.; Laakso, Markku; Lakatta, Edward G.; Langenberg, Claudia; Melander, Olle; Mook-Kanamori, Dennis O.; Palmer, Colin N. A.; Risch, Lorenz; Scott, Robert A.; Scott, Rodney J.; Sever, Peter; Spector, Tim D.; van der Harst, Pim; Wareham, Nicholas J.; Zeggini, Eleftheria; Levy, Daniel; Munroe, Patricia B.; Newton-Cheh, Christopher; Brown, Morris J.; Metspalu, Andres; Hung, Adriana M.; O'Donnell, Christopher J.; Edwards, Todd L.; Psaty, Bruce M.; Tzoulaki, Ioanna; Barnes, Michael R.; Wain, Louise V.; Elliott, Paul; Caulfield, Mark J. 分享 收藏
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits 超过100万人的遗传分析确定了535个与血压特征相关的新基因座 Evangelou, Evangelos; Warren, Helen R.; Mosen-Ansorena, David; Mifsu, Borbala; Pazoki, Raha; Gao, He; Ntritsos, Georgios; Dimou, Niki; Cabrer, Claudia P.; Karaman, Ibrahim; Ng, FuLiang; Evangelou, Marina; Witkowska, Katarzyna; Tzanis, Evan; Hellwege, Jacklyn N.; Giri, Ayush; Edwards, Digna R. Velez; Sun, Yan, V; Cho, Kelly; Gaziano, J. Michael; Wilson, Peter W. F.; Tsao, Philip S.; Kovesdy, Csaba P.; Esko, Tonu; Magi, Reedik; Milani, Lili; Almgren, Peter; Boutin, Thibaud; Debette, Stephanie; Ding, Jun; Giulianini, Franco; Holliday, Elizabeth G.; Jackson, Anne U.; Li-Gao, Ruifang; Lin, Wei-Yu; Luan, Jian'an; Mangino, Massimo; Oldmeadow, Christopher; Prins, Bram Peter; Qian, Yong; Sargurupremraj, Muralidharan; Shah, Nabi; Surendran, Praveen; Theriault, Sebastien; Verweij, Niek; Willems, Sara M.; Zhao, Jing-Hua; Amouyel, Philippe; Connell, John; de Mutsert, Renee; Doney, Alex S. F.; Farrall, Martin; Menni, Cristina; Morris, Andrew D.; Noordam, Raymond; Pare, Guillaume; Poulter, Neil R.; Shields, Denis C.; Stanton, Alice; Thom, Simon; Abecasis, Goncalo; Amin, Najaf; Arking, Dan E.; Ayers, Kristin L.; Barbieri, Caterina M.; Batini, Chiara; Bis, Joshua C.; Blake, Tineka; Bochud, Murielle; Boehnke, Michael; Boerwinkle, Eric; Boomsma, Dorret, I; Bottinger, Erwin P.; Braund, Peter S.; Brumat, Marco; Campbell, Archie; Campbell, Harry; Chakravarti, Aravinda; Chambers, John C.; Chauhan, Ganesh; Ciullo, Marina; Cocca, Massimiliano; Collins, Francis; Cordell, Heather J.; Davies, Gail; de Borst, Martin H.; de Geus, Eco J.; Deary, Ian J.; Deelen, Joris; Del Greco, Fabiola M.; Demirkale, Cumhur Yusuf; Doerr, Marcus; Ehret, Georg B.; Elosua, Roberto; Enroth, Stefan; Erzurumluoglu, A. Mesut; Ferreira, Teresa; Franberg, Mattias; Franco, Oscar H.; Gandin, Ilaria; Gasparini, Paolo; Giedraitis, Vilmantas; Gieger, Christian; Girotto, Giorgia; Goel, Anuj; Gow, Alan J.; Gudnason, Vilmundur; Guo, Xiuqing; Gyllensten, Ulf; Hamsten, Anders; Harris, Tamara B.; Harris, Sarah E.; Hartman, Catharina A.; Havulinna, Aki S.; Hicks, Andrew A.; Hofer, Edith; Hofman, Albert; Hottenga, Jouke-Jan; Huffman, Jennifer E.; Hwang, Shih-Jen; Ingelsson, Erik; James, Alan; Jansen, Rick; Jarvelin, Marjo-Riitta; Joehanes, Roby; Johansson, Asa; Johnson, Andrew D.; Joshi, Peter K.; Jousilahti, Pekka; Jukema, J. Wouter; Jula, Antti; Kahonen, Mika; Kathiresan, Sekar; Keavney, Bernard D.; Khaw, Kay-Tee; Knekt, Paul; Knight, Joanne; Kolcic, Ivana; Kooner, Jaspal S.; Koskinen, Seppo; Kristiansson, Kati; Kutalik, Zoltan; Laan, Maris; Larson, Marty; Launer, Lenore J.; Lehne, Benjamin; Lehtimaki, Terho; Liewald, David C. M.; Lin, Li; Lind, Lars; Lindgren, Cecilia M.; Liu, YongMei; Loos, Ruth J. F.; Lopez, Lorna M.; Lu, Yingchang; Lyytikainen, Leo-Pekka; Mahajan, Anubha; Mamasoula, Chrysovalanto; Marrugat, Jaume; Marten, Jonathan; Milaneschi, Yuri; Morgan, Anna; Morris, Andrew P.; Morrison, Alanna C.; Munson, Peter J.; Nalls, Mike A.; Nandakumar, Priyanka; Nelson, Christopher P.; Niiranen, Teemu; Nolte, Ilja M.; Nutile, Teresa; Oldehinkel, Albertine J.; Oostra, Ben A.; O'Reilly, Paul F.; Org, Elin; Padmanabhan, Sandosh; Palmas, Walter; Palotie, Aarno; Pattie, Alison; Penninx, Brenda W. J. H.; Perola, Markus; Peters, Annette; Polasek, Ozren; Pramstaller, Peter P.; Nguyen, Quang Tri; Raitakari, Olli T.; Ren, Meixia; Rettig, Rainer; Rice, Kenneth; Ridker, Paul M.; Ried, Janina S.; Riese, Harriette; Ripatti, Samuli; Robino, Antonietta; Rose, Lynda M.; Rotter, Jerome, I; Rudan, Igor; Ruggiero, Daniela; Saba, Yasaman; Sala, Cinzia F.; Salomaa, Veikko; Samani, Nilesh J.; Sarin, Antti-Pekka; Schmidt, Reinhold; Schmidt, Helena; Shrine, Nick; Siscovick, David; Smith, Albert, V; Snieder, Harold; Sober, Siim; Sorice, Rossella; Starr, John M.; Stott, David J.; Strachan, David P.; Strawbridge, Rona J.; Sundstrom, Johan; Swertz, Morris A.; Taylor, Kent D.; Teumer, Alexander; Tobin, Martin D.; Tomaszewski, Maciej; Toniolo, Daniela; Traglia, Michela; Trompet, Stella; Tuomilehto, Jaakko; Tzourio, Christophe; Uitterlinden, Andre G.; Vaez, Ahmad; van der Most, Peter J.; van Duijn, Cornelia M.; Vergnaud, Anne-Claire; Verwoert, Germaine C.; Vitart, Veronique; Voelker, Uwe; Vollenweider, Peter; Vuckovic, Dragana; Watkins, Hugh; Wild, Sarah H.; Willemsen, Gonneke; Wilson, James F.; Wright, Alan F.; Yao, Jie; Zemunik, Tatijana; Zhang, Weihua; Attia, John R.; Butterworth, Adam S.; Chasman, Daniell; Conen, David; Cucca, Francesco; Danesh, John; Hayward, Caroline; Howson, Joanna M. M.; Laakso, Markku; Lakatta, Edward G.; Langenberg, Claudia; Melander, Olle; Mook-Kanamori, Dennis O.; Palmer, Colin N. A.; Risch, Lorenz; Scott, Robert A.; Scott, Rodney J.; Sever, Peter; Spector, Tim D.; van der Harst, Pim; Wareham, Nicholas J.; Zeggini, Eleftheria; Levy, Daniel; Munroe, Patricia B.; Newton-Cheh, Christopher; Brown, Morris J.; Metspalu, Andres; Hung, Adriana M.; O'Donnell, Christopherj; Edwards, Todd L.; Psaty, Bruce M.; Tzoulaki, Ioanna; Barnes, Michael R.; Wain, Louise, V; Elliott, Paul; Caulfield, Mark J. 分享 收藏
GENETIC ANALYSIS OF OVER ONE MILLION PEOPLE IDENTIFIES 535 NOVEL LOCI ASSOCIATED WITH BLOOD PRESSURE AND RISK OF CARDIOVASCULAR DISEASE Warren, H. R.; Evangelou, E.; Mosen, D.; Mifsud, B.; Pazoki, R.; Gao, H.; Ntritsos, G.; Dimou, N.; Evangelou, M.; Hellwege, J.; Giri, A.; Esko, T.; Metspalu, A.; Tzoulaki, I.; Barnes, M. R.; Wain, L. V.; Elliott, P.; Caulfield, M. J. 分享 收藏
Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial Todd, John A.; Evangelou, Marina; Cutler, Antony J.; Pekalski, Marcin L.; Walker, Neil M.; Stevens, Helen E.; Porter, Linsey; Smyth, Deborah J.; Rainbow, Daniel B.; Ferreira, Ricardo C.; Esposito, Laura; Hunter, Kara M. D.; Loudon, Kevin; Irons, Kathryn; Yang, Jennie H.; Bell, Charles J. M.; Schuilenburg, Helen; Heywood, James; Challis, Ben; Neupane, Sankalpa; Clarke, Pamela; Coleman, Gillian; Dawson, Sarah; Goymer, Donna; Anselmiova, Katerina; Kennet, Jane; Brown, Judy; Caddy, Sarah L.; Lu, Jia; Greatorex, Jane; Goodfellow, Ian; Wallace, Chris; Tree, Tim I.; Evans, Mark; Mander, Adrian P.; Bond, Simon; Wicker, Linda S.; Waldron-Lynch, Frank 分享 收藏
Widespread seasonal gene expression reveals annual differences in human immunity and physiology Dopico, Xaquin Castro; Evangelou, Marina; Ferreira, Ricardo C.; Guo, Hui; Pekalski, Marcin L.; Smyth, Deborah J.; Cooper, Nicholas; Burren, Oliver S.; Fulford, Anthony J.; Hennig, Branwen J.; Prentice, Andrew M.; Ziegler, Anette-G.; Bonifacio, Ezio; Wallace, Chris; Todd, John A. 分享 收藏
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