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收藏分享 收藏 JALSG Ph (-) B-ALL213 Study: Pediatric-Type Chemotherapy Improves Prognosis in Adult Ph-Negative Acute Lymphoblastic Leukemia Patients, Including Older AdultsJALSG Ph (-) B-ALL213研究：儿科型化疗可改善成人Ph阴性急性淋巴细胞白血病患者的预后，包括老年患者。
Hatta, Yoshihiro; Hayakawa, Fumihiko; Yamazaki, Etsuko; Murayama, Tohru; Saito, Takeshi; Tanaka, Masatsugu; Doki, Noriko; Nishida, Tetsuya; Katsuoka, Yuna; Takada, Satoru; Sakamoto, Tatsuhiro; Sato, Shinya; Atsuta, Yoshiko; Ohtake, Shigeki; Sakaida, Emiko; Maeda, Yoshinobu; Yamauchi, Takahiro; Matsumura, Itaru; Miyazaki, Yasushi; Kiyoi, Hitoshi 分享 收藏 分享 收藏 BCL6 inhibition ameliorates resistance to ruxolitinib in CRLF2-rearranged acute lymphoblastic leukemiaTsuzuki, Shinobu; Yasuda, Takahiko; Goto, Hiroaki; Maeda, Naoko; Akahane, Koshi; Inukai, Takeshi; Yamamoto, Hideyuki; Karnan, Sivasundaram; Ota, Akinobu; Hyodo, Toshinori; Konishi, Hiroyuki; Hosokawa, Yoshitaka; Kiyoi, Hitoshi; Hayakawa, Fumihiko 分享 收藏 VWF-Gly2752Ser, a novel non-cysteine substitution variant in the CK domain, exhibits severe secretory impairment by hampering C-terminal dimer formationOkamoto, Shuichi; Tamura, Shogo; Sanda, Naomi; Odaira, Koya; Hayakawa, Yuri; Mukaide, Masato; Suzuki, Atsuo; Kanematsu, Takeshi; Hayakawa, Fumihiko; Katsumi, Akira; Kiyoi, Hitoshi; Kojima, Tetsuhito; Matsushita, Tadashi; Suzuki, Nobuaki 分享 收藏 F9mRNA splicing aberration due to a deep Intronic structural variation in a patient with moderate hemophilia BOdaira, Koya; Kawashima, Fumika; Tamura, Shogo; Suzuki, Nobuaki; Tokoro, Mahiru; Hayakawa, Yuri; Suzuki, Atsuo; Kanematsu, Takeshi; Okamoto, Shuichi; Takagi, Akira; Katsumi, Akira; Matsushita, Tadashi; Shima, Midori; Nogami, Keiji; Kojima, Tetsuhito; Hayakawa, Fumihiko 分享 收藏 Periosteum-derived podoplanin-expressing stromal cells regulate nascent vascularization during epiphyseal marrow developmentTamura, Shogo; Mukaide, Masato; Katsuragi, Yumi; Fujii, Wataru; Odaira, Koya; Suzuki, Nobuaki; Tsukiji, Nagaharu; Okamoto, Shuichi; Suzuki, Atsuo; Kanematsu, Takeshi; Katsumi, Akira; Takagi, Akira; Ikeda, Katsuhide; Ueyama, Jun; Hirayama, Masaaki; Suzuki-Inoue, Katsue; Matsushita, Tadashi; Kojima, Tetsuhito; Hayakawa, Fumihiko 分享 收藏 Transcriptome-wide subtyping of pediatric and adult T cell acute lymphoblastic leukemia in an international study of 707 casesDai, Yu-Ting; Zhang, Fan; Fang, Hai; Li, Jian-Feng; Lu, Gang; Jiang, Lu; Chen, Bing; Mao, Dong-Dong; Liu, Yuan-Fang; Wang, Jin; Peng, Li-Jun; Feng, Chong; Chen, Hai-Feng; Mu, Jun-Xi; Zhang, Qun-Ling; Wang, Hao; Ariffin, Hany; Moy, Tan Ah; Wang, Jing-Han; Lou, Yin-Jun; Chen, Su-Ning; Wang, Qian; Liu, Hong; Shan, Zhe; Matsumura, Itaru; Miyazaki, Yasushi; Yasuda, Takahiko; Dou, Li-Ping; Yan, Xiao-jing; Yan, Jin-Song; Yeoh, Allen Eng-Juh; Wu, De-Pei; Kiyoi, Hitoshi; Hayakawa, Fumihiko; Jin, Jie; Wang, Sheng-Yue; Sun, Xiao-Jian; Mi, Jian-Qing; Chen, Zhu; Huang, Jin-Yan; Chen, Sai-Juan 分享 收藏 Decision Analysis for Unrelated Bone Marrow Transplantation or Immediate Cord Blood Transplantation for Patients with Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia in First RemissionKako, Shinichi; Hayakawa, Fumihiko; Miyamura, Koichi; Tanaka, Junji; Imai, Kiyotoshi; Kanda, Junya; Morishima, Satoko; Uchida, Naoyuki; Doki, Noriko; Ikegame, Kazuhiro; Ozawa, Yukiyasu; Takada, Satoru; Usui, Noriko; Ohtake, Shigeki; Kiyoi, Hitoshi; Matsumura, Itaru; Miyazaki, Yasushi; Ichinohe, Tatsuo; Fukuda, Takahiro; Atsuta, Yoshiko; Kanda, Yoshinobu 分享 收藏 Protein S-Leu17Pro disrupts the hydrophobicity of its signal peptide causing a proteasome-dependent degradation蛋白质S-Leu17Pro破坏其信号肽的疏水性，导致蛋白酶体依赖性降解Okada, Kentaro; Tamura, Shogo; Suzuki, Nobuaki; Odaira, Koya; Mukaide, Masato; Fujii, Wataru; Katsuragi, Yumi; Suzuki, Atsuo; Kanematsu, Takeshi; Okamoto, Shuichi; Suzuki, Naruko; Katsumi, Akira; Matsushita, Tadashi; Kojima, Tetsuhito; Hayakawa, Fumihiko 分享 收藏 Dasatinib-based 2-step induction for adults with Philadelphia chromosome-positive acute lymphoblastic leukemiaSugiura, Isamu; Doki, Noriko; Hata, Tomoko; Cho, Ryuko; Ito, Toshiro; Suehiro, Youko; Tanaka, Masatsugu; Kako, Shinichi; Matsuda, Mitsuhiro; Yokoyama, Hisayuki; Ishikawa, Yuichi; Taniguchi, Yasuhiro; Hagihara, Maki; Ozawa, Yukiyasu; Ueda, Yasunori; Hirano, Daiki; Sakura, Toru; Tsuji, Masaaki; Kamae, Tsuyoshi; Fujita, Hiroyuki; Hiramoto, Nobuhiro; Onoda, Masahiro; Fujisawa, Shin; Hatta, Yoshihiro; Dobashi, Nobuaki; Nishiwaki, Satoshi; Atsuta, Yoshiko; Kobayashi, Yukio; Hayakawa, Fumihiko; Ohtake, Shigeki; Naoe, Tomoki; Miyazaki, Yasushi 分享 收藏 Exosomes secreted from cancer-associated fibroblasts elicit anti-pyrimidine drug resistance through modulation of its transporter in malignant lymphoma恶性淋巴瘤中肿瘤相关成纤维细胞分泌的外泌体通过调节其转运体引起抗嘧啶耐药性Kunou, Shunsuke; Shimada, Kazuyuki; Takai, Mika; Sakamoto, Akihiko; Aoki, Tomohiro; Hikita, Tomoya; Kagaya, Yusuke; Iwamoto, Eisuke; Sanada, Masashi; Shimada, Satoko; Hayakawa, Fumihiko; Oneyama, Chitose; Kiyoi, Hitoshi 分享 收藏 Essential role of a carboxyl-terminal α-helix motif in the secretion of coagulation factor XIHayakawa, Yuri; Tamura, Shogo; Suzuki, Nobuaki; Odaira, Koya; Tokoro, Mahiru; Kawashima, Fumika; Hayakawa, Fumihiko; Takagi, Akira; Katsumi, Akira; Suzuki, Atsuo; Okamoto, Shuichi; Kanematsu, Takeshi; Matsushita, Tadashi; Kojima, Tetsuhito 分享 收藏 Staurosporine and venetoclax induce the caspase-dependent proteolysis of MEF2D-fusion proteins and apoptosis in MEF2D-fusion (+) ALL cellsTange, Naoyuki; Hayakawa, Fumihiko; Yasuda, Takahiko; Odaira, Koya; Yamamoto, Hideyuki; Hirano, Daiki; Sakai, Toshiyasu; Terakura, Seitaro; Tsuzuki, Shinobu; Kiyoi, Hitoshi 分享 收藏 Targeting MEF2D-fusion Oncogenic Transcriptional Circuitries in B-cell Precursor Acute Lymphoblastic LeukemiaTsuzuki, Shinobu; Yasuda, Takahiko; Kojima, Shinya; Kawazu, Masahito; Akahane, Koshi; Inukai, Takeshi; Imaizumi, Masue; Morishita, Takanobu; Miyamura, Koichi; Ueno, Toshihide; Karnan, Sivasundaram; Ota, Akinobu; Hyodo, Toshinori; Konishi, Hiroyuki; Sanada, Masashi; Nagai, Hirokazu; Horibe, Keizo; Tomita, Akihiro; Suzuki, Kyogo; Muramatsu, Hideki; Takahashi, Yoshiyuki; Miyazaki, Yasushi; Matsumura, Itaru; Kiyoi, Hitoshi; Hosokawa, Yoshitaka; Mano, Hiroyuki; Hayakawa, Fumihiko 分享 收藏 High prevalence ofMEF2Dfusion in human B-cell precursor acute lymphoblastic leukemia cell lines人b细胞前体急性淋巴细胞白血病细胞系中mef2d融合的高患病率Akahane, Koshi; Yasuda, Takahiko; Tsuzuki, Shinobu; Hayakawa, Fumihiko; Kiyokawa, Nobutaka; Somazu, Shinpei; Watanabe, Atsushi; Kagami, Keiko; Abe, Masako; Harama, Daisuke; Goi, Kumiko; Kawazu, Masahito; Kojima, Shinya; Imamura, Toshihiko; Goto, Hiroaki; Iwamoto, Shotaro; Minegishi, Masayoshi; Abe, Masafumi; Hojo, Hiroshi; Inaba, Toshiya; Mano, Hiroyuki; Sugita, Kanji; Inukai, Takeshi 分享 收藏 Higher FVIII:C measured by chromogenic substrate assay than by one-stage assay is associated with silent hemophilic arthropathy通过显色底物测定法测得的FVIII:C高于通过一阶段测定法测得的FVIII:C与沉默的血友病性关节炎有关Ogawa, Mika; Suzuki, Nobuaki; Takahashi, Nobunori; Tamura, Shogo; Suzuki, Atsuo; Suzuki, Sachiko; Hattori, Yuua; Kakihara, Misaki; Kanematsu, Takeshi; Kojima, Toshihisa; Katsumi, Akira; Hayakawa, Fumihiko; Kojima, Tetsuhito; Ishiguro, Naoki; Kiyoi, Hitoshi; Matsushita, Tadashi 分享 收藏 ZNF384-fusion proteins have high affinity for the transcriptional coactivator EP300 and aberrant transcriptional activitiesYamamoto, Hideyuki; Hayakawa, Fumihiko; Yasuda, Takahiko; Odaira, Koya; Minamikawa, Yuka; Tange, Naoyuki; Hirano, Daiki; Kojima, Yuki; Morishita, Takanobu; Tsuzuki, Shinobu; Naoe, Tomoki; Kiyoi, Hitoshi 分享 收藏 Apparent synonymous mutation F9 c.87A > G causes secretion failure by in-frame mutation with aberrant splicingOdaira, Koya; Tamura, Shogo; Suzuki, Nobuaki; Kakihara, Misaki; Hattori, Yuna; Tokoro, Mahiru; Suzuki, Sachiko; Takagi, Akira; Katsumi, Akira; Hayakawa, Fumihiko; Okamoto, Shuichi; Suzuki, Atsuo; Kanematsu, Takeshi; Matsushita, Tadashi; Kojima, Tetsuhito 分享 收藏 
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