未登录 Disruption of the TP53 locus in osteosarcoma leads to TP53 promoter gene fusions and restoration of parts of the TP53 signalling pathway 骨肉瘤中TP53基因座的破坏导致TP53启动子基因融合和部分TP53信号通路的恢复 Saba, Karim H.; Difilippo, Valeria; Kovac, Michal; Cornmark, Louise; Magnusson, Linda; Nilsson, Jenny; van den Bos, Hilda; Spierings, Diana C. J.; Bidgoli, Mahtab; Jonson, Tord; Sumathi, Vaiyapuri P.; Brosjoe, Otte; Staaf, Johan; Foijer, Floris; Styring, Emelie; Nathrath, Michaela; Baumhoer, Daniel; Nord, Karolin H. 分享 收藏
Expression of OCT4 isoforms is reduced in primary colorectal cancer Turyova, Eva; Mikolajcik, Peter; Grendar, Marian; Kudelova, Eva; Holubekova, Veronika; Kalman, Michal; Marcinek, Juraj; Hrnciar, Matej; Kovac, Michal; Miklusica, Juraj; Laca, Ludovit; Lasabova, Zora 分享 收藏
The early evolutionary landscape of osteosarcoma provides clues for targeted treatment strategies Kovac, Michal; Ameline, Baptiste; Ribi, Sebastian; Kovacova, Monika; Cross, William; Barenboim, Maxim; Witt, Olaf; Bielack, Stefan; Krieg, Andreas; Hartmann, Wolfgang; Nathrath, Michaela; Baumhoer, Daniel 分享 收藏
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Loss ofNF2defines a genetic subgroup ofnon-FOS-rearranged osteoblastoma Saba, Karim H.; Cornmark, Louise; Hofvander, Jakob; Magnusson, Linda; Nilsson, Jenny; van den Bos, Hilda; Spierings, Diana C. J.; Foijer, Floris; Staaf, Johan; Brosjo, Otte; Sumathi, Vaiyapuri P.; Lam, Suk Wai; Szuhai, Karoly; Bovee, Judith V. M. G.; Kovac, Michal; Baumhoer, Daniel; Styring, Emelie; Nord, Karolin H. 分享 收藏
Germline RET variants underlie a subset of paediatric osteosarcoma Kovac, Michal; Woolley, Connor; Ribi, Sebastian; Blattmann, Claudia; Roth, Eva; Morini, Marco; Kovacova, Monika; Ameline, Baptiste; Kulozik, Andreas; Bielack, Stefan; Hartmann, Wolfgang; Ballinger, Mandy L.; Thomas, David M.; Tomlinson, Ian; Nathrath, Michaela; Heinimann, Karl; Baumhoer, Daniel 分享 收藏
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Prexasertib (LY2606368) reduces clonogenic survival by inducing apoptosis in primary patient-derived osteosarcoma cells and synergizes with cisplatin and talazoparib Heidler, Christopher L.; Roth, Eva K.; Thiemann, Markus; Blattmann, Claudia; Perez, Ramon L.; Huber, Peter E.; Kovac, Michal; Amthor, Beate; Neu-Yilik, Gabriele; Kulozik, Andreas E. 分享 收藏
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Convergent Evolution of Copy Number Alterations in Multi-Centric Hepatocellular Carcinoma Lackner, Carolin; Quagliata, Luca; Cross, William; Ribi, Sebastian; Heinimann, Karl; Paradiso, Viola; Quintavalle, Cristina; Kovacova, Monika; Baumhoer, Daniel; Piscuoglio, Salvatore; Terracciano, Luigi; Kovac, Michal 分享 收藏
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Activating mutations in the MAP-kinase pathway define non-ossifying fibroma of bone MAP-激酶途径中的激活突变定义了骨的非骨化性纤维瘤 Baumhoer, Daniel; Kovac, Michal; Sperveslage, Jan; Ameline, Baptiste; Strobl, Anna-Christina; Krause, Arthur; Trautmann, Marcel; Wardelmann, Eva; Nathrath, Michaela; Hoeller, Sylvia; Hardes, Jendrik; Gosheger, Georg; Krieg, Andreas H.; Vieth, Volker; Tirabosco, Roberto; Amary, Fernanda; Flanagan, Adrienne M.; Hartmann, Wolfgang 分享 收藏
The evolutionary landscape of colorectal tumorigenesis 结直肠肿瘤发生的进化景观 Cross, William; Kovac, Michal; Mustonen, Ville; Temko, Daniel; Davis, Hayley; Baker, Ann-Marie; Biswas, Sujata; Arnold, Roland; Chegwidden, Laura; Gatenbee, Chandler; Anderson, Alexander R.; Koelzer, Viktor H.; Martinez, Pierre; Jiang, Xiaowei; Domingo, Enric; Woodcock, Dan J.; Feng, Yun; Kovacova, Monika; Maughan, Tim; Jansen, Marnix; Rodriguez-Justo, Manuel; Ashraf, Shazad; Guy, Richard; Cunningham, Christopher; East, James E.; Wedge, David C.; Wang, Lai Mun; Palles, Claire; Heinimann, Karl; Sottoriva, Andrea; Leedham, Simon J.; Graham, Trevor A.; Tomlinson, Ian P. M. 分享 收藏
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Genome-wide analysis of somatic copy number alterations and chromosomal breakages in osteosarcoma Smida, Jan; Xu, Hongen; Zhang, Yanping; Baumhoer, Daniel; Ribi, Sebastian; Kovac, Michal; von Luettichau, Irene; Bielack, Stefan; O'Leary, Valerie B.; Leib-Moesch, Christine; Frishman, Dmitrij; Nathrath, Michaela 分享 收藏
Differential clonal evolution in oesophageal cancers in response to neo-adjuvant chemotherapy Findlay, John M.; Castro-Giner, Francesc; Makino, Seiko; Rayner, Emily; Kartsonaki, Christiana; Cross, William; Kovac, Michal; Ulahannan, Danny; Palles, Claire; Gillies, Richard S.; MacGregor, Thomas P.; Church, David; Maynard, Nicholas D.; Buffa, Francesca; Cazier, Jean-Baptiste; Graham, Trevor A.; Wang, Lai-Mun; Sharma, Ricky A.; Middleton, Mark; Tomlinson, Ian 分享 收藏
Exome sequencing of osteosarcoma reveals mutation signatures reminiscent of BRCA deficiency Kovac, Michal; Blattmann, Claudia; Ribi, Sebastian; Smida, Jan; Mueller, Nikola S.; Engert, Florian; Castro-Giner, Francesc; Weischenfeldt, Joachim; Kovacova, Monika; Krieg, Andreas; Andreou, Dimosthenis; Tunn, Per-Ulf; Duerr, Hans Roland; Rechl, Hans; Schaser, Klaus-Dieter; Melcher, Ingo; Burdach, Stefan; Kulozik, Andreas; Specht, Katja; Heinimann, Karl; Fulda, Simone; Bielack, Stefan; Jundt, Gernot; Tomlinson, Ian; Korbel, Jan O.; Nathrath, Michaela; Baumhoer, Daniel 分享 收藏
GNAS mutations are not detected in parosteal and low-grade central osteosarcomas Salinas-Souza, Carolina; De Andrea, Carlos; Bihl, Michel; Kovac, Michal; Pillay, Nischalan; Forshew, Tim; Gutteridge, Alice; Ye, Hongtao; Amary, M. Fernanda; Tirabosco, Roberto; Toledo, Silvia Regina Caminada; Baumhoer, Daniel; Flanagan, Adrienne M. 分享 收藏
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