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D

David A. Jacobson

Vanderbilt University School of Medicine
H指数:38
被引数:3,535

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The diabetes-associated K+ channel TALK-2 controls human beta cell endoplasmic reticulum Ca2+ handling, which promotes basal insulin release and limits glucose-stimulated insulin secretion

糖尿病相关K+通道TALK-2调控人β细胞内质网Ca2+处理,这促进基础胰岛素释放并限制葡萄糖刺激的胰岛素分泌。

2026-02-250
OA
Glycolytic activation of β-cell Na+/K+-ATPases containing β1-subunits accelerates Na+ extrusion, prolonging the duration of Ca2+ oscillations but decreasing insulin secretion

含β1亚基的β细胞Na+/K+-ATP酶的糖酵解激活加速Na+外排,延长Ca2+振荡的持续时间,但降低胰岛素分泌。

2025-12-040
OAAI
Atf4 Protects Islet β-Cell Identity and Function Under Acute Glucose-Induced Stress but Promotes β-Cell Failure in the Presence of Free Fatty Acid

Atf4在急性葡萄糖诱导的应激条件下保护胰岛β细胞身份和功能,但在游离脂肪酸存在的情况下促进β细胞功能衰竭。

2025-02-030
PRE
Glucose-Dependent miR-125b Is a Negative Regulator of β-Cell Function

葡萄糖依赖性miR-125b是 β 细胞功能的负调节因子

2022-04-2714
OA