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巩

巩长旸 (Changyang Gong)

sichuan university

52H指数
185论文数
1.0W被引数
收录论文 128
发表时间
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Metalloimmunological hydrogel-based cancer vaccine potentiates postoperative tumor immunotherapy金属免疫学水凝胶基癌症疫苗增强术后肿瘤免疫治疗
errNature Communications
IF15.7
err2026-08-20
err0
errOAAI
errTao He; Xiaorong Kou; Ye Sang; Duo Sun; Rui Luo; Liping Bai; Shuqin Wang; Jiayi Cao; Huile Gao; Zichao Luo; Changyang Gong
err分享
err收藏
Hydrated microRNA-regulating nanoplatform for synergistic lubrication and anti-inflammation to alleviate osteoarthritis水合microRNA调控纳米平台通过协同润滑和抗炎作用缓解骨关节炎
errActa Pharmaceutica Sinica B
IF14.6
err2026-07-09
err0
errOAAI
errLimin Wu; Chunqing Ou; Mingyang Li; Dongxue Huang; Xingyu Gou; Qiwei Li; Meiling Shen; Changyang Gong; Qinjie Wu; Bin Shen
err分享
err收藏
Programmable Tumor-Activated NanoCRISPR Platform Synergizes cGAS-STING Activation With PD-L1 Blockade for Potentiated Antitumor Immunity可编程肿瘤激活的NanoCRISPR平台协同cGAS-STING激活与PD-L1阻断以增强抗肿瘤免疫
errAdvanced Functional Materials
IF19
err2026-06-17
err0
PREAI
errLiping Bai; Xinyue Wu; Xiaorong Kou; Miaomiao Zhang; Xinchao Li; Ning Wang; Xue Wu; Qinjie Wu; Changyang Gong
err分享
err收藏
Multistage Responsive NanoCRISPR Unleashes Cascade Amplified Endogenous Apoptosis and Inhibits Epithelial-Mesenchymal Transition Simultaneously for Suppressing Tumor Growth and Metastasis多阶段响应型NanoCRISPR同时释放级联放大的内源性凋亡并抑制上皮-间质转化以抑制肿瘤生长和转移
errACS Nano
IF16
err2026-05-13
err0
PREAI
errLi Wang; Chao Liu; Jin Yang; Xiaowei Liu; Ruiping Huai; Xinxin Wang; Linjiang Song; Zhike Li; Qinjie Wu; Changyang Gong
err分享
err收藏
A hierarchical self-adjuvanted nanoCRISPR-based vaccine restores endogenous immune recognition and surveillance to amplify adaptive immune responses基于分级自佐剂纳米CRISPR的疫苗恢复内源性免疫识别和监视以放大适应性免疫应答
errBiomaterials
IF12.9
err2026-05-09
err0
PREAI
errDongxue Huang; Duo Sun; Chunqing Ou; Xiaoli Zhang; Rui Luo; Xiaorong Kou; Xinchao Li; Yingjie Li; Hao Le; Wenmei Li; Yanjie You; Changyang Gong
err分享
err收藏
A harmless-to-harmful switchable and spatiotemporally activated nano-CRISPR hierarchically amplifies ferroptosis in melanoma一种无害至有害可切换且时空激活的纳米CRISPR分级放大黑色素瘤中的铁死亡
errCell Reports Medicine
IF10.6
err2026-03-31
err0
errOAAI
errChunqing Ou; Xianzhou Huang; Dongxue Huang; Rui Luo; Ruhan Chen; Xinchao Li; Xinyue Wu; Qinjie Wu; Changyang Gong
err分享
err收藏
Bladder adaptive hydrogel scaffold with dual release, antimicrobial, immunomodulatory, and repair: DRIVER for urinary tract infections具有双重释放、抗菌、免疫调节和修复功能的膀胱适应性水凝胶支架：泌尿道感染的驱动因素
errActa Pharmaceutica Sinica B
IF14.6
err2026-01-06
err0
errOAAI
errZhimin Tan; Yu Liu; Xinchao Li; Qiyu He; Tao He; Qian Li; Changyang Gong
err分享
err收藏
Limitation-circumventing and strength-capitalizing hydrogel potentiates durable antitumor immunity and robust abscopal effect in radiotherapy克服限制并利用强度的水凝胶可增强放疗的持久抗肿瘤免疫和显著远隔效应
errTheranostics
IF13.3
err2026-01-01
err0
PREAI
errLi, Haijun; Huang, Xianzhou; Yang, Jin; Bai, Liping; Shen, Meiling; Zhao, Yaqin; Gong, Changyang; You, Yanjie; Wu, Qinjie
err分享
err收藏
ROS-sensitive nanocarriers for synergistic X-PDT/chemo/immunotherapy of triple-negative breast cancer and metastasisROS敏感型纳米载体用于三阴性乳腺癌及其转移的协同X-PDT/化疗/免疫治疗
errActa Biomaterialia
IF9.6
err2025-12-16
err0
PREAI
errChaorong Wei; Lingke Feng; Jing Liu; Mingxia Xu; Yongsheng Cui; Fengyi Lin; Honglian Yu; Zhanzhan Feng; Hong Zhang; Changyang Gong; Peng Mi
err分享
err收藏
A HO-1 gene knockout using a NanoCRISPR scaffold suppresses metastasis in mouse models使用NanoCRISPR支架进行的HO-1基因敲除在 mouse 模型中抑制了转移。
errNature Biomedical Engineering
IF26.6
err2025-10-22
err0
PREAI
errNing Wang; Zichao Luo; Chao Liu; Jialin Ma; Xinyue Wu; Qinjie Wu; Xiaogang Liu; Changyang Gong
err分享
err收藏
Cholesterol modified defense peptide as an EMP2-siRNA delivery system for synergistic immunogene therapy against breast cancer胆固醇修饰的防御肽作为EMP2-siRNA递送系统，用于协同免疫基因治疗对抗乳腺癌
errMaterials Today Bio
IF10.2
err2025-09-18
err0
errOAAI
errXiaoyun Wang; Siliang Chen; Gu He; Yanghui Zhu; Nan Zhang; Changyang Gong; Xiang Li; Yujuan Chen
err分享
err收藏
A self-cascade nanoCRISPR prompts transcellular penetration to potentiate gene editing and tumor killing自级联纳米CRISPR促进跨细胞穿透以增强基因编辑和肿瘤杀伤
errActa Pharmaceutica Sinica B
IF14.6
err2025-09-08
err0
errOAAI
errChao Liu; Yangsong Xu; Ning Wang; Hongyu Liu; Xi Yang; Shiyao Zhou; Dongxue Huang; Yingjie Li; Yanjie You; Qinjie Wu; Changyang Gong
err分享
err收藏
Hypoxia-activated and status-reversing hydrogel platform initiates potent systemic immunity against triple-negative breast cancer低氧激活和状态逆转的水凝胶平台可诱导三阴性乳腺癌的强效系统性免疫。
errCHEMICAL ENGINEERING JOURNAL
IF13.2
err2025-07-01
err0
PREAI
errLi, Zhike; Huang, Xianzhou; Yang, Jin; Shen, Meiling; You, Yanjie; Wu, Qinjie; Gong, Changyang
err分享
err收藏
Advancements in CRISPR/Cas systems for disease treatmentCRISPR/Cas系统在疾病治疗方面的进展
errActa Pharmaceutica Sinica B
IF14.6
err2025-05-17
err0
errOAAI
errYangsong Xu; Hao Le; Qinjie Wu; Ning Wang; Changyang Gong
err分享
err收藏
Implantable Immunostimulant Microneedle Patch for Post-Surgical Prevention of Cancer Recurrence and Distant Tumor Inhibition可植入免疫刺激微针贴片用于术后预防癌症复发和远处肿瘤抑制
errACS APPLIED MATERIALS & INTERFACES
IF8.2
err2025-04-07
err0
PREAI
errLuo, ZC; Li, XC; Zhu, DD; Fu, WX; Liu, YX; Zheng, LW; Chen, P; Gong, CY; Liu, XG
err分享
err收藏
Icaritin Represses Autophagy to Promote Colorectal Cancer Cell Apoptosis and Sensitized Low-Temperature Photothermal Therapy via Targeting HSP90-TXNDC9 Interactions伊卡替芬通过靶向HSP90-TXNDC9相互作用来抑制自噬，促进结直肠癌细胞凋亡，并增强低温光热疗法的敏感性。
errADVANCED SCIENCE
IF14.1
err2025-04-04
err1
errOAAI
errHe, D; Chen, SL; Wang, XY; Wen, X; Gong, CY; Liu, L; He, G
err分享
err收藏
Glucocorticoid pre-administration improves LNP-mRNA mediated protein replacement and genome editing therapies
errINTERNATIONAL JOURNAL OF PHARMACEUTICS
IF5.2
err2025-03-01
err0
PREAI
errLi, Li; Luo, Mei; Zhou, Lifang; Wang, Yanhong; Jiao, Yaoge; Wang, Chunting; Gong, Changyang; Cen, Xiaobo; Yao, Shaohua
err分享
err收藏
A Radiation-Activated and Self-Cascade Nano-Immunostimulator Triggers a Potent Abscopal Effect Against Distant Tumors一种辐射激活的自级联纳米免疫刺激剂可触发对远处肿瘤的强效远隔效应
errADVANCED FUNCTIONAL MATERIALS
IF19
err2025-02-19
err0
PREAI
errShao, BF; Liang, XQ; Xiang, ZZ; Liu, F; Zeng, YY; He, T; Zhu, SY; Li, XC; Gao, HL; Mi, P; Liu, L; Gong, CY
err分享
err收藏
Nanovesicles for Lipid Metabolism Reprogram-Enhanced Ferroptosis and Magnetotherapy of Refractory Tumors and Inhibiting Metastasis with Activated Innate Immunity纳米囊泡用于脂质代谢重编程增强的难治性肿瘤的铁死亡与磁疗及激活固有免疫抑制转移
errACS NANO
IF16
err2025-02-10
err1
PREAI
errCheng, XQ; Xu, JS; Cui, YS; Liu, J; Chen, YT; He, CS; Cui, LL; Liu, YY; Song, B; Gong, CY; Mi, P
err分享
err收藏
Fisetin micelles precisely exhibit a radiosensitization effect by inhibiting PDGFR β/STAT1/STAT3/Bcl-2 signaling pathway in tumor
errCHINESE CHEMICAL LETTERS
IF8.9
err2025-02-01
err0
PREAI
errZeng, Yuanyuan; Liu, Fang; Wang, Jun; Shao, Bianfei; He, Tao; Xiang, Zhongzheng; Wang, Yan; Zhu, Shunyao; Yang, Tian; Yu, Siting; Gong, Changyang; Liu, Lei
err分享
err收藏

研究方向

主要研究领域为针对肿瘤治疗的新型自组装基因疫苗和药物递送系统新型免疫佐剂纳米生物技术医用生物材料
合作学者
合作期刊
陈豪 封面图
陈豪 (Hao Chen)
H 指数: 139 · 论文数: 5.6K
刘晓刚 封面图
刘晓刚 (Xiaogang Liu)
H 指数: 117 · 论文数: 739
J
Jiahuai Han
H 指数: 117 · 论文数: 397
Y
Yuquan Wei
H 指数: 111 · 论文数: 1.2K
X
Xian Jun Loh
H 指数: 110 · 论文数: 643
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