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GWAS Identifies Pharmacogenetic Markers Associated with Premedication-Related Pegaspargase Hypersensitivity and Toxicities in Pediatric and Adolescent Young Adults (AYAs) with Acute Lymphoblastic Leukemia or Lymphoma 全基因组关联研究(GWAS)确定了与急性淋巴细胞白血病或淋巴瘤患儿及青少年年轻成人(AYAs)预用药相关培门冬酶超敏反应和毒性的药物遗传学标志物。 Shastri, Vivek M.; Ahmed, Jennifer; Spin, Eva; Morales, Sonia; Agrawal, Anurag K.; Phillips, Christine L.; August, Keith J.; Guest, Erin M.; Lin, Carol Hwang; Winger, Beth Apsel; Aftandilian, Catherine; Huynh, Van Thu; Lamba, Jatinder K. 分享 收藏
Phase 1/1b Dose Escalation and Expansion of CPX-351 in Combination with Gemtuzumab Ozogamicin in Newly Diagnosed Acute Myeloid Leukemia I期/II期剂量递增和扩展研究:CPX-351联合Gemtuzumab Ozogamicin治疗新诊断急性髓性白血病 Chan, Onyee; Sweet, Kendra L.; Talati, Chetasi; Zahra, Fatima Tuz; Nardelli, Lisa Ann; Lamba, Jatinder K.; Kim, Jongphil; Song, Jinming; Xie, Zhuoer; Yun, Seongseok; Kuykendall, Andrew T.; Padron, Eric; Walker, Alison R.; Komrokji, Rami S.; Lancet, Jeffrey E.; Sallman, David 分享 收藏
Rapid Long-Read Epigenomic Diagnosis and Prognosis of Acute Myeloid Leukemia 快速长读长表观基因组学对急性髓系白血病的诊断与预后 Marchi, Francisco; Schade, Ann-Kathrin; Shastri, Vivek M.; Cao, Xueyuan; Ribeiro, Raul C.; Rubnitz, Jeffrey E.; Klco, Jeffery M.; Gamis, Alan S.; Ries, Rhonda E.; Kolb, Anders; Aplenc, Richard; Alonzo, Todd A.; Pounds, Stanley; Meshinchi, Soheil; Lamba, Jatinder K. 分享 收藏
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Integrated drug resistance and leukemic stemness gene-expression scores predict outcomes in large cohort of over 3500 AML patients from 10 trials Elsayed, Abdelrahman H.; Cao, Xueyuan; Marrero, Richard J.; Nguyen, Nam H. K.; Wu, Huiyun; Ni, Yonhui; Ribeiro, Raul C.; Tobias, Herold; Valk, Peter J.; Beliveau, Francois; Richard-Carpentier, Guillaume; Hebert, Josee; Zwaan, C. Michel; Gamis, Alan; Kolb, Edward Anders; Aplenc, Richard; Alonzo, Todd A.; Meshinchi, Soheil; Rubnitz, Jeffrey; Pounds, Stanley; Lamba, Jatinder K. 分享 收藏
SAMHD1 single nucleotide polymorphisms impact outcome in children with newly diagnosed acute myeloid leukemia SAMHD1单核苷酸多态性对初诊急性髓系白血病患儿预后的影响 Marrero, Richard J.; Cao, Xueyuan; Wu, Huiyun; Elsayed, Abdelrahman H.; Klco, Jeffery M.; Ribeiro, Raul C.; Rubnitz, Jeffrey E.; Ma, Xiaotu; Meshinchi, Soheil; Aplenc, Richard; Kolb, E. Anders; Ries, Rhonda E.; Alonzo, Todd A.; Pounds, Stanley B.; Lamba, Jatinder K. 分享 收藏
Genome-wide CRISPR/Cas9 screen identifies etoposide response modulators associated with clinical outcomes in pediatric AML Nguyen, Nam H. K.; Rafiee, Roya; Tagmount, Abderrahmane; Sobh, Amin; Loguinov, Alex; Sosa, Angelica K. de Jesus; Elsayed, Abdelrahman H.; Gbadamosi, Mohammed; Seligson, Nathan; Cogle, Christopher R.; Rubnitz, Jeffery; Ribeiro, Raul; Downing, James; Cao, Xueyuan; Pounds, Stanley B.; Vulpe, Christopher D.; Lamba, Jatinder K. 分享 收藏
PARP1 and POLD2 as prognostic biomarkers for multiple myeloma in autologous stem cell transplant Thomas, Melissa; Li, Junan; King, Kevan; Persaud, Avinash K.; Duah, Ernest; Vangundy, Zachary; Hofmeister, Craig C.; Lamba, Jatinder K.; Tan, Aik Choon; Fridley, Brooke L.; Poi, Ming J.; Seligson, Nathan D. 分享 收藏
Prospective Validation and Refinement of a Population Pharmacokinetic Model of Fludarabine in Children and Young Adults Undergoing Hematopoietic Cell Transplantation Brooks, Jordan T.; Solans, Belen P.; Lu, Ying; Kharbanda, Sandhya; Dvorak, Christopher C.; Lalefar, Nahal; Long, Susie; Gupta, Ashish O.; Horn, Biljana; Lamba, Jatinder K.; Huang, Liusheng; Apsel-Winger, Beth; Keizer, Ron J.; Savic, Rada; Long-Boyle, Janel 分享 收藏
Total marrow irradiation reduces organ damage and enhances tissue repair with the potential to increase the targeted dose of bone marrow in both young and old mice Lim, Ji Eun; Madabushi, Srideshikan Sargur; Vishwasrao, Paresh; Song, Joo Y.; Abdelhamid, Amr M. H.; Ghimire, Hemendra; Vanishree, V. L.; Lamba, Jatinder K.; Dandapani, Savita; Salhotra, Amandeep; Lemecha, Mengistu; Pierini, Antonio; Zhao, Daohong; Storme, Guy; Holtan, Shernan; Aristei, Cynthia; Schaue, Dorthe; Al Malki, Monzr; Hui, Susanta K. 分享 收藏