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Parkinson's disease mutant Miro1 causes mitochondrial dysfunction and dopaminergic neuron loss 帕金森病突变型Miro1导致线粒体功能障碍和多巴胺能神经元丢失 Chemla, Axel; Arena, Giuseppe; Sacripanti, Ginevra; Barmpa, Kyriaki; Zagare, Alise; Garcia, Pierre; Gorgogietas, Vyron; Antony, Paul; Ohnmacht, Jochen; Baron, Alexandre; Jung, Jaqueline; Mogensen, Frida Lind-Holm; Michelucci, Alessandro; Marzesco, Anne-Marie; Buttini, Manuel; Schmidt, Thorsten; Grunewald, Anne; Schwamborn, Jens C.; Kruger, Rejko; Saraiva, Claudia 分享 收藏
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Exploring environmental modifiers of LRRK2-associated Parkinson's disease penetrance: An exposomics and metagenomics pilot study on household dust Andujar, Begona Talavera; Pereira, Sandro L.; Busi, Susheel Bhanu; Usnich, Tatiana; Borsche, Max; Ertan, Sibel; Bauer, Peter; Rolfs, Arndt; Hezzaz, Soraya; Ghelfi, Jenny; Brueggemann, Norbert; Antony, Paul; Wilmes, Paul; Klein, Christine; Gruenewald, Anne; Schymanski, Emma L. 分享 收藏
Metformin impacts the differentiation of mouse bone marrow cells into macrophages affecting tumour immunity Scafidi, Andrea; Mogensen, Frida Lind-Holm; Campus, Eleonora; Pailas, Alexandros; Neumann, Katrin; Legrave, Nathalie; Bernardin, Francois; Pereira, Sandro L.; Antony, Paul M. A.; Nicot, Nathalie; Mittelbronn, Michel; Grunewald, Anne; Nazarov, Petr, V; Poli, Aurelie; Van Dyck, Eric; Michelucci, Alessandro 分享 收藏
PARK7/DJ-1 deficiency impairs microglial activation in response to LPS-induced inflammation Mogensen, Frida Lind-Holm; Sousa, Carole; Ameli, Corrado; Badanjak, Katja; Pereira, Sandro L.; Muller, Arnaud; Kaoma, Tony; Coowar, Djalil; Scafidi, Andrea; Poovathingal, Suresh K.; Tziortziou, Maria; Antony, Paul M. A.; Nicot, Nathalie; Ginolhac, Aurelien; Weisenhorn, Daniela M. Vogt; Wurst, Wolfgang; Poli, Aurelie; Nazarov, Petr V.; Skupin, Alexander; Gruenewald, Anne; Michelucci, Alessandro 分享 收藏
Polygenic Risk Scores Validated in Patient-Derived Cells Stratify for Mitochondrial Subtypes of Parkinson's Disease 在帕金森氏病线粒体亚型的患者衍生细胞中验证的多基因风险评分 Arena, Giuseppe; Landoulsi, Zied; Grossmann, Dajana; Payne, Thomas; Vitali, Armelle; Delcambre, Sylvie; Baron, Alexandre; Antony, Paul; Boussaad, Ibrahim; Bobbili, Dheeraj Reddy; Sreelatha, Ashwin Ashok Kumar; Pavelka, Lukas; Diederich, Nico; Klein, Christine; Seibler, Philip; Glaab, Enrico; Foltynie, Thomas; Bandmann, Oliver; Sharma, Manu; Kruger, Rejko; May, Patrick; Gruenewald, Anne 分享 收藏
Accurate long-read sequencing identified GBA1 as major risk factor in the Luxembourgish Parkinson's study 在卢森堡帕金森研究中，准确的长读测序将GBA1确定为主要危险因素 Pachchek, Sinthuja; Landoulsi, Zied; Pavelka, Lukas; Schulte, Claudia; Buena-Atienza, Elena; Gross, Caspar; Hauser, Ann-Kathrin; Reddy Bobbili, Dheeraj; Casadei, Nicolas; May, Patrick; Kruger, Rejko; Acharya, Geeta; Aguayo, Gloria; Alexandre, Myriam; Ali, Muhammad; Ammerlann, Wim; Arena, Giuseppe; Balling, Rudi; Bassis, Michele; Batutu, Roxane; Beaumont, Katy; Becker, Regina; Bellora, Camille; Berchem, Guy; Berg, Daniela; Bisdorff, Alexandre; Boussaad, Ibrahim; Bouvier, David; Brockmann, Kathrin; Calmes, Jessica; Castillo, Lorieza; Contesotto, Gessica; De Bremaeker, Nancy; Diederich, Nico; Dondelinger, Rene; E. Ramia, Nancy; Esteves, Daniela; Fagherazzi, Guy; Ferrand, Jean-Yves; Frauenknecht, Katrin; Gantenbein, Manon; Gasser, Thomas; Gawron, Piotr; Ghosh, Soumyabrata; Giraitis, Marijus; Glaab, Enrico; Goergen, Martine; Gomez De Lope, Elisa; Graas, Jerome; Graziano, Mariella; Groues, Valentin; Grunewald, Anne; Gu, Wei; Hammot, Gael; Hanff, Anne-Marie; Hansen, Linda; Heneka, Michael; Henry, Estelle; Herbrink, Sylvia; Herzinger, Sascha; Heymann, Michael; Hu, Michele; Hundt, Alexander; Jacoby, Nadine; Jaroslaw Lebioda, Jacek; Jarosz, Yohan; Jonsdottir, Sonja; Klopfenstein, Quentin; Klucken, Jochen; Lambert, Pauline; Lentz, Roseline; Liepelt, Inga; Liszka, Robert; Longhino, Laura; Lorentz, Victoria; Lupu, Paula Cristina; Marques, Taina M.; Mackay, Clare; Maetzler, Walter; Marcus, Katrin; Marques, Guilherme; Martins Conde, Patricia; Mcintyre, Deborah; Mediouni, Chouaib; Meisch, Francoise; Menster, Myriam; Minelli, Maura; Mittelbronn, Michel; Mollenhauer, Brit; Muhlschlegel, Friedrich; Nati, Romain; Nehrbass, Ulf; Nickels, Sarah; Nicolai, Beatrice; Nicolay, Jean-Paul; Noor, Fozia; Ostaszewski, Marek; P. C. Gomes, Clarissa; Pauly, Claire; Pauly, Laure; Perquin, Magali; Ramos Lima, Rosalina; Rauschenberger, Armin; Rawal, Rajesh; Roomp, Kirsten; Rosales, Eduardo; Rosety, Isabel; Sandt, Estelle; Sapienza, Stefano; Satagopam, Venkata; Schmitt, Margaux; Schmitz, Sabine; Schneider, Reinhard; Schwamborn, Jens; Severino, Raquel; Sharify, Amir; Soboleva, Ekaterina; Sokolowska, Kate; Thien, Hermann; Thiry, Elodie; Ting Jiin Loo, Rebecca; Trefois, Christophe; Trouet, Johanna; Tsurkalenko, Olena; Vaillant, Michel; Valenti, Mesele; Van Cutsem, Gilles; Vega, Carlos; Vilas Boas, Liliana; Vyas, Maharshi; Wade-Martins, Richard; Wilmes, Paul; Wollscheid-Lengeling, Evi; Zelimkhanov, Gelani 分享 收藏
Comparison of two protocols for the generation of iPSC-derived human astrocytes 两种用于产生iPSC衍生的人星形胶质细胞的方案的比较 Mulica, Patrycja; Venegas, Carmen; Landoulsi, Zied; Badanjak, Katja; Delcambre, Sylvie; Tziortziou, Maria; Hezzaz, Soraya; Ghelfi, Jenny; Smajic, Semra; Schwamborn, Jens; Krueger, Rejko; Antony, Paul; May, Patrick; Glaab, Enrico; Gruenewald, Anne; Pereira, Sandro L. 分享 收藏
Interaction of Mitochondrial Polygenic Score and Lifestyle Factors in LRRK2 p.Gly2019Ser Parkinsonism Lueth, Theresa; Gabbert, Carolin; Koch, Sebastian; Koenig, Inke R.; Caliebe, Amke; Laabs, Bjoern-Hergen; Hentati, Faycel; Ben Sassi, Samia; Amouri, Rim; Spielmann, Malte; Klein, Christine; Gruenewald, Anne; Farrer, Matthew J.; Trinh, Joanne 分享 收藏
Mitochondria-Endoplasmic Reticulum Contact Sites Dynamics and Calcium Homeostasis Are Differentially Disrupted in PINK1-PD or PRKN-PD Neurons Grossmann, Dajana; Malburg, Nina; Glass, Hannes; Weeren, Veronika; Sondermann, Verena; Pfeiffer, Julia F. F.; Petters, Janine; Lukas, Jan; Seibler, Philip; Klein, Christine; Gruenewald, Anne; Hermann, Andreas 分享 收藏
Genome-wide case-only analysis of gene-gene interactions with known Parkinson's disease risk variants reveals link between LRRK2 and SYT10 Aleknonyte-Resch, Milda; Trinh, Joanne; Leonard, Hampton; Delcambre, Sylvie; Leitao, Elsa; Lai, Dongbing; Smajic, Semra; Orr-Urtreger, Avi; Thaler, Avner; Blauwendraat, Cornelis; Sharma, Arunabh B.; Makarious, Mary B.; Kim, Jonggeol Jeff; Lake, Julie; Rahmati, Pegah; Freitag-Wolf, Sandra; Seibler, Philip; Foroud, Tatiana B.; Singleton, Andrew B.; Gruenewald, Anne; Kaiser, Frank; Klein, Christine; Krawczak, Michael; Dempfle, Astrid 分享 收藏
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From methylation to myelination: epigenomic and transcriptomic profiling of chronic inactive demyelinated multiple sclerosis lesions Tiane, Assia; Schepers, Melissa; Reijnders, Rick A.; van Veggel, Lieve; Chenine, Sarah; Rombaut, Ben; Dempster, Emma; Verfaillie, Catherine; Wasner, Kobi; Gruenewald, Anne; Prickaerts, Jos; Pishva, Ehsan; Hellings, Niels; van den Hove, Daniel; Vanmierlo, Tim 分享 收藏
Molecular phenotypes of mitochondrial dysfunction in clinically non-manifesting heterozygous PRKN variant carriers 临床上无杂合PRKN变异携带者线粒体功能障碍的分子表型 Rueda, Maria Paulina Castelo; Zanon, Alessandra; Gilmozzi, Valentina; Lavdas, Alexandros A.; Raftopoulou, Athina; Delcambre, Sylvie; Del Greco, Fabiola; Klein, Christine; Gruenewald, Anne; Pramstaller, Peter P.; Hicks, Andrew A.; Pichler, Irene 分享 收藏
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