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A chromatin-focused CRISPR screen identifies USP22 as a barrier to somatic cell reprogramming 以染色质为重点的CRISPR筛选鉴定USP22为体细胞重编程的障碍 Gurhan, Gulben; Sevinc, Kenan; Aztekin, Can; Gayretli, Mert; Yilmaz, Alperen; Yildiz, Abdullah Burak; Ervatan, Elif Naz; Morova, Tunc; Datli, Elif; Coleman, Oliver D.; Kawamura, Akane; Lack, Nathan A.; Syed, Hamzah; Onder, Tamer 分享 收藏
Identification of selective SWI/SNF dependencies in enzalutamide-resistant prostate cancer Gokbayrak, Bengul; Altintas, Umut Berkay; Lingadahalli, Shreyas; Morova, Tunc; Huang, Chia-Chi Flora; Fazlioglu, Betul Ersoy; Yu, Ivan Pak Lok; Kalkan, Batuhan M.; Cejas, Paloma; Kung, Sonia H. Y.; Fazli, Ladan; Kawamura, Akane; Long, Henry W.; Acilan, Ceyda; Onder, Tamer T.; Bagci-Onder, Tugba; Lynch, James T.; Lack, Nathan A. 分享 收藏
Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival Ozyerli-Goknar, Ezgi; Kala, Ezgi Yagmur; Aksu, Ali Cenk; Bulut, Ipek; Cingoz, Ahmet; Nizamuddin, Sheikh; Biniossek, Martin; Seker-Polat, Fidan; Morova, Tunc; Aztekin, Can; Kung, Sonia H. Y.; Syed, Hamzah; Tuncbag, Nurcan; Gonen, Mehmet; Philpott, Martin; Cribbs, Adam P.; Acilan, Ceyda; Lack, Nathan A.; Onder, Tamer T.; Timmers, H. T. Marc; Bagci-Onder, Tugba 分享 收藏
BRD9-containing non-canonical BAF complex maintains somatic cell transcriptome and acts as a barrier to human reprogramming Sevinc, Kenan; Cavga, Derya; Philpott, Martin; Kelekci, Simge; Can, Hazal; Cribbs, Adam P.; Yildiz, Abdullah Burak; Yilmaz, Alperen; Ayar, Enes Sefa; Dunford, James E.; Ata, Deniz; Sigua, Logan H.; Qi, Jun; Oppermann, Udo; Onder, Tamer T. 分享 收藏
EPIKOL, a chromatin-focused CRISPR/Cas9-based screening platform, to identify cancer-specific epigenetic vulnerabilities Yedier-Bayram, Ozlem; Gokbayrak, Bengul; Kayabolen, Alisan; Aksu, Ali Cenk; Cavga, Ayse Derya; Cingoz, Ahmet; Kala, Ezgi Yagmur; Karabiyik, Goktug; Gunsay, Rauf; Esin, Beril; Morova, Tunc; Uyulur, Firat; Syed, Hamzah; Philpott, Martin; Cribbs, Adam P.; Kung, Sonia H. Y.; Lack, Nathan A.; Onder, Tamer T.; Bagci-Onder, Tugba 分享 收藏
Genome-wide CRISPR screen identifies PRC2 and KMT2D-COMPASS as regulators of distinct EMT trajectories that contribute differentially to metastasis Zhang, Yun; Donaher, Joana Liu; Das, Sunny; Li, Xin; Reinhardt, Ferenc; Krall, Jordan A.; Lambert, Arthur W.; Thiru, Prathapan; Keys, Heather R.; Khan, Mehreen; Hofree, Matan; Wilson, Molly M.; Yedier-Bayram, Ozlem; Lack, Nathan A.; Onder, Tamer T.; Bagci-Onder, Tugba; Tyler, Michael; Tirosh, Itay; Regev, Aviv; Lees, Jacqueline A.; Weinberg, Robert A. 分享 收藏
AF10 (MLLT10) prevents somatic cell reprogramming through regulation of DOT1L-mediated H3K79 methylation AF10 (MLLT10) 通过调节DOT1L-mediated H3K79甲基化阻止体细胞重编程 Ugurlu-Cimen, Deniz; Odluyurt, Deniz; Sevinc, Kenan; Ozkan-Kucuk, Nazli Ezgi; Ozcimen, Burcu; Demirtas, Deniz; Enustun, Eray; Aztekin, Can; Philpott, Martin; Oppermann, Udo; Ozlu, Nurhan; Onder, Tamer T. 分享 收藏
Development, characterization, and hematopoietic differentiation of Griscelli syndrome type 2 induced pluripotent stem cells Guney-Esken, Gulen; Erol, Ozgur Dogus; Pervin, Burcu; Sevinc, Gulben Gurhan; Onder, Tamer; Bilgic, Elif; Korkusuz, Petek; Gunel-Ozcan, Aysen; Uckan-Cetinkaya, Duygu; Aerts-Kaya, Fatima 分享 收藏
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Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function (vol 47, pg 183, 2017) Takata, Kazuyuki; Kozaki, Tatsuya; Lee, Christopher Zhe Wei; Thion, Morgane Sonia; Otsuka, Masayuki; Lim, Shawn; Utami, Kagistia Hana; Fidan, Kerem; Park, Dong Shin; Malleret, Benoit; Chakarov, Svetoslav; See, Peter; Low, Donovan; Low, Gillian; Garcia-Miralles, Marta; Zeng, Ruizhu; Zhang, Jinqiu; Goh, Chi Ching; Gul, Ahmet; Hubert, Sandra; Lee, Bernett; Chen, Jinmiao; Low, Ivy; Shadan, Nurhidaya Binte; Lum, Josephine; Wei, Tay Seok; Mok, Esther; Kawanishi, Shohei; Kitamura, Yoshihisa; Larbi, Anis; Poidinger, Michael; Renia, Laurent; Ng, Lai Guan; Wolf, Yochai; Jung, Steffen; Onder, Tamer; Newell, Evan; Huber, Tara; Ashihara, Eishi; Garel, Sonia; Pouladi, Mahmoud A.; Ginhoux, Florent 分享 收藏
Systematic characterization of chromatin modifying enzymes identifies KDM3B as a critical regulator in castration resistant prostate cancer Sarac, Hilal; Morova, Tunc; Pires, Elisabete; McCullagh, James; Kaplan, Anil; Cingoz, Ahmet; Bagci-Onder, Tugba; onder, Tamer; Kawamura, Akane; Lack, Nathan A. 分享 收藏
Robust, Long-Term Culture of Endoderm-Derived Hepatic Organoids for Disease Modeling Akbari, Soheil; Sevinc, Gulben Gurhan; Ersoy, Nevin; Basak, Onur; Kaplan, Kubra; Sevinc, Kenan; Ozel, Erkin; Sengun, Berke; Enustun, Eray; Ozcimen, Burcu; Bagriyanik, Alper; Arslan, Nur; Onder, Tamer Tevfik; Erdal, Esra 分享 收藏
Systems-level Analysis Reveals Multiple Modulators of Epithelial-mesenchymal Transition and Identifies DNAJB4 and CD81 as Novel Metastasis Inducers in Breast Cancer Kagiali, Zeynep Cansu Uretmen; Sanal, Erdem; Karayel, Ozge; Polat, Ayse Nur; Saatci, Ozge; Ersan, Pelin Gulizar; Trappe, Kathrin; Renard, Bernhard Y.; Onder, Tamer T.; Tuncbag, Nurcan; Sahin, Ozgur; Ozlu, Nurhan 分享 收藏
Bromodomain inhibition of the coactivators CBP/EP300 facilitate cellular reprogramming Ebrahimi, Ayyub; Sevinc, Kenan; Sevinc, Gulben Gurhan; Cribbs, Adam P.; Philpott, Martin; Uyulur, Firat; Morova, Tunc; Dunford, James E.; Goklemez, Sencer; Ari, Sule; Oppermann, Udo; Onder, Tamer T. 分享 收藏
Epigenetic Reprogramming of Lineage-Committed Human Mammary Epithelial Cells Requires DNMT3A and Loss of DOT1L Breindel, Jerrica L.; Skibinski, Adam; Sedic, Maja; Wronski-Campos, Ania; Zhou, Wenhui; Keller, Patricia J.; Mills, Joslyn; Bradner, James; Onder, Tamer; Kuperwasser, Charlotte 分享 收藏
Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function Takata, Kazuyuki; Kozaki, Tatsuya; Lee, Christopher Zhe Wei; Thion, Morgane Sonia; Otsuka, Masayuki; Lim, Shawn; Utami, Kagistia Hana; Fidan, Kerem; Park, Dong Shin; Malleret, Benoit; Chakarov, Svetoslav; See, Peter; Low, Donovan; Low, Gillian; Garcia-Miralles, Marta; Zeng, Ruizhu; Zhang, Jinqiu; Goh, Chi Ching; Gul, Ahmet; Hubert, Sandra; Lee, Bernett; Chen, Jinmiao; Low, Ivy; Shadan, Nurhidaya Binte; Lum, Josephine; Wei, Tay Seok; Mok, Esther; Kawanishi, Shohei; Kitamura, Yoshihisa; Larbi, Anis; Poidinger, Michael; Renia, Laurent; Ng, Lai Guan; Wolf, Yochai; Jung, Steffen; Onder, Tamer; Newell, Evan; Huber, Tara; Ashihara, Eishi; Garel, Sonia; Pouladi, Mahmoud A.; Ginhoux, Florent 分享 收藏
KDM2B, an H3K36-specific demethylase, regulates apoptotic response of GBM cells to TRAIL Kurt, Ibrahim Cagri; Sur, Ilknur; Kaya, Ezgi; Cingoz, Ahmet; Kazancioglu, Selena; Kahya, Zeynep; Toparlak, Omer Duhan; Senbabaoglu, Filiz; Kaya, Zeynep; Ozyerli, Ezgi; Karahseyinoglu, Sercin; Lack, Nathan A.; Gumus, Zeynep H.; Onder, Tamer T.; Bagci-Onder, Tugba 分享 收藏
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