未登录TIME-VARYING MEDIATION ANALYSIS FOR INCOMPLETE DATA WITH APPLICATION TO DNA METHYLATION STUDY FOR PTSD针对不完整数据的时变中介分析及其在PTSD DNA甲基化研究中的应用
Wei, Kecheng; Xue, Fei; Xu, Qi; Yuan, Yubai; Zhang, Yuexia; Qin, Guoyou; Wani, Agaz H.; Aiello, Allison E.; Wildman, Derek E.; Uddin, Monica; Qu, Annie .png)
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收藏分享 收藏 Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder全基因组关联分析确定了95个风险位点，并提供了创伤后应激障碍的神经生物学见解Nievergelt, Caroline M.; Maihofer, Adam X.; Atkinson, Elizabeth G.; Chen, Chia-Yen; Choi, Karmel W.; Coleman, Jonathan R. I.; Daskalakis, Nikolaos P.; Duncan, Laramie E.; Polimanti, Renato; Aaronson, Cindy; Amstadter, Ananda B.; Andersen, Soren B.; Andreassen, Ole A.; Arbisi, Paul A.; Ashley-Koch, Allison E.; Austin, S. Bryn; Avdibegovic, Esmina; Babic, Dragan; Bacanu, Silviu-Alin; Baker, Dewleen G.; Batzler, Anthony; Beckham, Jean C.; Belangero, Sintia; Benjet, Corina; Bergner, Carisa; Bierer, Linda M.; Biernacka, Joanna M.; Bierut, Laura J.; Bisson, Jonathan I.; Boks, Marco P.; Bolger, Elizabeth A.; Brandolino, Amber; Breen, Gerome; Bressan, Rodrigo Affonseca; Bryant, Richard A.; Bustamante, Angela C.; Bybjerg-Grauholm, Jonas; Baekvad-Hansen, Marie; Borglum, Anders D.; Borte, Sigrid; Cahn, Leah; Calabrese, Joseph R.; Caldas-de-Almeida, Jose Miguel; Chatzinakos, Chris; Cheema, Sheraz; Clouston, Sean A. P.; Colodro-Conde, Lucia; Coombes, Brandon J.; Cruz-Fuentes, Carlos S.; Dale, Anders M.; Dalvie, Shareefa; Davis, Lea K.; Deckert, Jurgen; Delahanty, Douglas L.; Dennis, Michelle F.; Desarnaud, Frank; DiPietro, Christopher P.; Disner, Seth G.; Docherty, Anna R.; Domschke, Katharina; Dyb, Grete; Kulenovic, Alma Dzubur; Edenberg, Howard J.; Evans, Alexandra; Fabbri, Chiara; Fani, Negar; Farrer, Lindsay A.; Feder, Adriana; Feeny, Norah C.; Flory, Janine D.; Forbes, David; Franz, Carol E.; Galea, Sandro; Garrett, Melanie E.; Gelaye, Bizu; Gelernter, Joel; Geuze, Elbert; Gillespie, Charles F.; Goleva, Slavina B.; Gordon, Scott D.; Goci, Aferdita; Grasser, Lana Ruvolo; Guindalini, Camila; Haas, Magali; Hagenaars, Saskia; Hauser, Michael A.; Heath, Andrew C.; Hemmings, Sian M. J.; Hesselbrock, Victor; Hickie, Ian B.; Hogan, Kelleigh; Hougaard, David Michael; Huang, Hailiang; Huckins, Laura M.; Hveem, Kristian; Jakovljevic, Miro; Javanbakht, Arash; Jenkins, Gregory D.; Johnson, Jessica; Jones, Ian; Jovanovic, Tanja; Karstoft, Karen-Inge; Kaufman, Milissa L.; Kennedy, James L.; Kessler, Ronald C.; Khan, Alaptagin; Kimbrel, Nathan A.; King, Anthony P.; Koen, Nastassja; Kotov, Roman; Kranzler, Henry R.; Krebs, Kristi; Kremen, William S.; Kuan, Pei-Fen; Lawford, Bruce R.; Lebois, Lauren A. M.; Lehto, Kelli; Levey, Daniel F.; Lewis, Catrin; Liberzon, Israel; Linnstaedt, Sarah D.; Logue, Mark W.; Lori, Adriana; Lu, Yi; Luft, Benjamin J.; Lupton, Michelle K.; Luykx, Jurjen J.; Makotkine, Iouri; Maples-Keller, Jessica L.; Marchese, Shelby; Marmar, Charles; Martin, Nicholas G.; Martinez-Levy, Gabriela A.; McAloney, Kerrie; McFarlane, Alexander; McLaughlin, Katie A.; McLean, Samuel A.; Medland, Sarah E.; Mehta, Divya; Meyers, Jacquelyn; Michopoulos, Vasiliki; Mikita, Elizabeth A.; Milani, Lili; Milberg, William; Miller, Mark W.; Morey, Rajendra A.; Morris, Charles Phillip; Mors, Ole; Mortensen, Preben Bo; Mufford, Mary S.; Nelson, Elliot C.; Nordentoft, Merete; Norman, Sonya B.; Nugent, Nicole R.; O'Donnell, Meaghan; Orcutt, Holly K.; Pan, Pedro M.; Panizzon, Matthew S.; Pathak, Gita A.; Peters, Edward S.; Peterson, Alan L.; Peverill, Matthew; Pietrzak, Robert H.; Polusny, Melissa A.; Porjesz, Bernice; Powers, Abigail; Qin, Xue-Jun; Ratanatharathorn, Andrew; Risbrough, Victoria B.; Roberts, Andrea L.; Rothbaum, Alex O.; Rothbaum, Barbara O.; Roy-Byrne, Peter; Ruggiero, Kenneth J.; Rung, Ariane; Runz, Heiko; Rutten, Bart P. F.; de Viteri, Stacey Saenz; Salum, Giovanni Abrahao; Sampson, Laura; Sanchez, Sixto E.; Santoro, Marcos; Seah, Carina; Seedat, Soraya; Seng, Julia S.; Shabalin, Andrey; Sheerin, Christina M.; Silove, Derrick; Smith, Alicia K.; Smoller, Jordan W.; Sponheim, Scott R.; Stein, Dan J.; Stensland, Synne; Stevens, Jennifer S.; Sumner, Jennifer A.; Teicher, Martin H.; Thompson, Wesley K.; Tiwari, Arun K.; Trapido, Edward; Uddin, Monica; Ursano, Robert J.; Valdimarsdottir, Unnur; Van Hooff, Miranda; Vermetten, Eric; Vinkers, Christiaan H.; Voisey, Joanne; Wang, Yunpeng; Wang, Zhewu; Waszczuk, Monika; Weber, Heike; Wendt, Frank R.; Werge, Thomas; Williams, Michelle A.; Williamson, Douglas E.; Winsvold, Bendik S.; Winternitz, Sherry; Wolf, Christiane; Wolf, Erika J.; Xia, Yan; Xiong, Ying; Yehuda, Rachel; Young, Keith A.; Young, Ross Mcd; Zai, Clement C.; Zai, Gwyneth C.; Zervas, Mark; Zhao, Hongyu; Zoellner, Lori A.; Zwart, John-Anker; DeRoon-Cassini, Terri; Van Rooij, Sanne J. H.; van den Heuvel, Leigh L.; Stein, Murray B.; Ressler, Kerry J.; Koenen, Karestan C. 分享 收藏 Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference抑郁症的多血统全基因组关联研究艾滋病基因座发现，精细定位，基因优先排序和因果推断Meng, Xiangrui; Navoly, Georgina; Giannakopoulou, Olga; Levey, Daniel F.; Koller, Dora; Pathak, Gita A.; Koen, Nastassja; Lin, Kuang; Adams, Mark J.; Renteria, Miguel E.; Feng, Yanzhe; Gaziano, J. Michael; Stein, Dan J.; Zar, Heather J.; Campbell, Megan L.; van Heel, David A.; Trivedi, Bhavi; Finer, Sarah; McQuillin, Andrew; Bass, Nick; Chundru, V. Kartik; Martin, Hilary C.; Huang, Qin Qin; Valkovskaya, Maria; Chu, Chia-Yi; Kanjira, Susan; Kuo, Po-Hsiu; Chen, Hsi-Chung; Tsai, Shih-Jen; Liu, Yu-Li; Kendler, Kenneth S.; Peterson, Roseann E.; Cai, Na; Fang, Yu; Sen, Srijan; Scott, Laura J.; Burmeister, Margit; Loos, Ruth J. F.; Preuss, Michael H.; Actkins, Ky'Era V.; Davis, Lea K.; Uddin, Monica; Wani, Agaz H.; Wildman, Derek E.; Aiello, Allison E.; Ursano, Robert J.; Kessler, Ronald C.; Kanai, Masahiro; Okada, Yukinori; Sakaue, Saori; Rabinowitz, Jill A.; Maher, Brion S.; Uhl, George; Eaton, William; Cruz-Fuentes, Carlos S.; Martinez-Levy, Gabriela A.; Campos, Adrian I.; Millwood, Iona Y.; Chen, Zhengming; Li, Liming; Wassertheil-Smoller, Sylvia; Jiang, Yunxuan; Tian, Chao; Martin, Nicholas G.; Mitchell, Brittany L.; Byrne, Enda M.; Awasthi, Swapnil; Coleman, Jonathan R. I.; Ripke, Stephan; Sofer, Tamar; Walters, Robin G.; McIntosh, Andrew M.; Polimanti, Renato; Dunn, Erin C.; Stein, Murray B.; Gelernter, Joel; Lewis, Cathryn M.; Kuchenbaecker, Karoline 分享 收藏 Does biological age mediate the relationship between childhood adversity and depression? Insights from the Detroit Neighborhood Health StudyMartinez, Rae Anne M.; Howard, Annie Green; Fernandez-Rhodes, Lindsay; Maselko, Joanna; Pence, Brian W.; Dhingra, Radhika; Galea, Sandro; Uddin, Monica; Wildman, Derek E.; Aiello, Allison E. 分享 收藏 LEVERAGING MULTI-OMIC DATA TO INTERPRET AN EPIGENOME-WIDE META-ANALYSIS OF PTSD IN 23 MILITARY AND CIVILIAN COHORTSSmith, Alicia; Katrinli, Seyma; Wani, Agaz H.; Maihofer, Adam X.; Zannas, Anthony S.; Nugent, Nicole; Xhao, Xiang; Nievergelt, Caroline M.; Uddin, Monica; Logue, Mark 分享 收藏 EPIGENOME-WIDE META-ANALYSIS OF > 3200 MILITARY AND CIVILIAN PARTICIPANTS IDENTIFIES CELL-TYPE SPECIFIC DNA METHYLATION SIGNALS ASSOCIATED WITH PTSDKatrinli, Seyma; Wani, Agaz H.; Zhao, Xiang; Maihofer, Adam X.; Zhao, Ying; Nunez, Diana; Montalvo-Ortiz, Janitza; Zannas, Anthony S.; Logue, Mark; Nievergelt, Caroline M.; Uddin, Monica; Smith, Alicia K. 分享 收藏 A Mendelian randomization study of genetic liability to post-traumatic stress disorder and risk of ischemic strokeSoremekun, Opeyemi; Musanabaganwa, Clarisse; Uwineza, Annette; Ardissino, Maddalena; Rajasundaram, Skanda; Wani, Agaz H.; Jansen, Stefan; Mutabaruka, Jean; Rutembesa, Eugene; Soremekun, Chisom; Cheickna, Cisse; Wele, Mamadou; Mugisha, Joseph; Nash, Oyekanmi; Kinyanda, Eugene; Nitsch, Dorothea; Fornage, Myriam; Chikowore, Tinashe; Gill, Dipender; Wildman, Derek E.; Mutesa, Leon; Uddin, Monica; Fatumo, Segun 分享 收藏 分享 收藏 分享 收藏 Rare copy number variation in posttraumatic stress disorder创伤后应激障碍中罕见的拷贝数变异Maihofer, Adam X.; Engchuan, Worrawat; Huguet, Guillaume; Klein, Marieke; MacDonald, Jeffrey R.; Shanta, Omar; Thiruvahindrapuram, Bhooma; Jean-louis, Martineau; Saci, Zohra; Jacquemont, Sebastien; Scherer, Stephen W.; Ketema, Elizabeth; Aiello, Allison E.; Amstadter, Ananda B.; Avdibegovic, Esmina; Babic, Dragan; Baker, Dewleen G.; Bisson, Jonathan, I; Boks, Marco P.; Bolger, Elizabeth A.; Bryant, Richard A.; Bustamante, Angela C.; Caldas-de-Almeida, Jose Miguel; Cardoso, Graca; Deckert, Jurgen; Delahanty, Douglas L.; Domschke, Katharina; Dunlop, Boadie W.; Dzubur-Kulenovic, Alma; Evans, Alexandra; Feeny, Norah C.; Franz, Carol E.; Gautam, Aarti; Geuze, Elbert; Goci, Aferdita; Hammamieh, Rasha; Jakovljevic, Miro; Jett, Marti; Jones, Ian; Kaufman, Milissa L.; Kessler, Ronald C.; King, Anthony P.; Kremen, William S.; Lawford, Bruce R.; Lebois, Lauren A. M.; Lewis, Catrin; Liberzon, Israel; Linnstaedt, Sarah D.; Lugonja, Bozo; Luykx, Jurjen J.; Lyons, Michael J.; Mavissakalian, Matig R.; McLaughlin, Katie A.; McLean, Samuel A.; Mehta, Divya; Mellor, Rebecca; Morris, Charles Phillip; Muhie, Seid; Orcutt, Holly K.; Peverill, Matthew; Ratanatharathorn, Andrew; Risbrough, Victoria B.; Rizzo, Albert; Roberts, Andrea L.; Rothbaum, Alex O.; Rothbaum, Barbara O.; Roy-Byrne, Peter; Ruggiero, Kenneth J.; Rutten, Bart P. F.; Schijven, Dick; Seng, Julia S.; Sheerin, Christina M.; Sorenson, Michael A.; Teicher, Martin H.; Uddin, Monica; Ursano, Robert J.; Vinkers, Christiaan H.; Voisey, Joanne; Weber, Heike; Winternitz, Sherry; Xavier, Miguel; Yang, Ruoting; Young, Ross McD; Zoellner, Lori A.; Salem, Rany M.; Shaffer, Richard A.; Wu, Tianying; Ressler, Kerry J.; Stein, Murray B.; Koenen, Karestan C.; Sebat, Jonathan; Nievergelt, Caroline M. 分享 收藏 Community engagement in epigenomic and neurocognitive research on post-traumatic stress disorder in Rwandans exposed to the 1994 genocide against the Tutsi: lessons learned社区参与针对图西族的1994种族灭绝的卢旺达人的创伤后应激障碍的表观基因组学和神经认知研究: 经验教训Musanabaganwa, Clarisse; Jansen, Stefan; Wani, Agaz; Rugamba, Alex; Mutabaruka, Jean; Rutembesa, Eugene; Uwineza, Annette; Fatumo, Segun; Hermans, Erno J.; Souopgui, Jacob; Wildman, Derek E.; Uddin, Monica; Roozendaal, Benno; Njemini, Rose; Mutesa, Leon 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information通过整合定量表型和创伤暴露信息来增强创伤后应激障碍的遗传变异发现Maihofer, Adam X.; Choi, Karmel W.; Coleman, Jonathan R., I; Daskalakis, Nikolaos P.; Denckla, Christy A.; Ketema, Elizabeth; Morey, Rajendra A.; Polimanti, Renato; Ratanatharathorn, Andrew; Torres, Katy; Wingo, Aliza P.; Zai, Clement C.; Aiello, Allison E.; Almli, Lynn M.; Amstadter, Ananda B.; Andersen, Soren B.; Andreassen, Ole A.; Arbisi, Paul A.; Ashley-Koch, Allison E.; Austin, S. Bryn; Avdibegovic, Esmina; Borglum, Anders D.; Babic, Dragan; Baekvad-Hansen, Marie; Baker, Dewleen G.; Beckham, Jean C.; Bierut, Laura J.; Bisson, Jonathan, I; Boks, Marco P.; Bolger, Elizabeth A.; Bradley, Bekh; Brashear, Meghan; Breen, Gerome; Bryant, Richard A.; Bustamante, Angela C.; Bybjerg-Grauholm, Jonas; Calabrese, Joseph R.; Caldas-de-Almeida, Jose M.; Chen, Chia-Yen; Dale, Anders M.; Dalvie, Shareefa; Deckert, Jurgen; Delahanty, Douglas L.; Dennis, Michelle F.; Disner, Seth G.; Domschke, Katharina; Duncan, Laramie E.; Kulenovic, Alma Dzubur; Erbes, Christopher R.; Evans, Alexandra; Farrer, Lindsay A.; Feeny, Norah C.; Flory, Janine D.; Forbes, David; Franz, Carol E.; Galea, Sandro; Garrett, Melanie E.; Gautam, Aarti; Gelaye, Bizu; Gelernter, Joel; Geuze, Elbert; Gillespie, Charles F.; Goci, Aferdita; Gordon, Scott D.; Guffanti, Guia; Hammamieh, Rasha; Hauser, Michael A.; Heath, Andrew C.; Hemmings, Sian M. J.; Hougaard, David Michael; Jakovljevic, Miro; Jett, Marti; Johnson, Eric Otto; Jones, Ian; Jovanovic, Tanja; Qin, Xue-Jun; Karstoft, Karen-Inge; Kaufman, Milissa L.; Kessler, Ronald C.; Khan, Alaptagin; Kimbrel, Nathan A.; King, Anthony P.; Koen, Nastassja; Kranzler, Henry R.; Kremen, William S.; Lawford, Bruce R.; Lebois, Lauren A. M.; Lewis, Catrin; Liberzon, Israel; Linnstaedt, Sarah D.; Logue, Mark W.; Lori, Adriana; Lugonja, Bozo; Luykx, Jurjen J.; Lyons, Michael J.; Maples-Keller, Jessica L.; Marmar, Charles; Martin, Nicholas G.; Maurer, Douglas; Mavissakalian, Matig R.; McFarlane, Alexander; McGlinchey, Regina E.; McLaughlin, Katie A.; McLean, Samuel A.; Mehta, Divya; Mellor, Rebecca; Michopoulos, Vasiliki; Milberg, William; Miller, Mark W.; Morris, Charles Phillip; Mors, Ole; Mortensen, Preben B.; Nelson, Elliot C.; Nordentoft, Merete; Norman, Sonya B.; O'Donnell, Meaghan; Orcutt, Holly K.; Panizzon, Matthew S.; Peters, Edward S.; Peterson, Alan L.; Peverill, Matthew; Pietrzak, Robert H.; Polusny, Melissa A.; Rice, John P.; Risbrough, Victoria B.; Roberts, Andrea L.; Rothbaum, Alex O.; Rothbaum, Barbara O.; Roy-Byrne, Peter; Ruggiero, Kenneth J.; Rung, Ariane; Rutten, Bart P. F.; Saccone, Nancy L.; Sanchez, Sixto E.; Schijven, Dick; Seedat, Soraya; Seligowski, Antonia, V; Seng, Julia S.; Sheerin, Christina M.; Silove, Derrick; Smith, Alicia K.; Smoller, Jordan W.; Sponheim, Scott R.; Stein, Dan J.; Stevens, Jennifer S.; Teicher, Martin H.; Thompson, Wesley K.; Trapido, Edward; Uddin, Monica; Ursano, Robert J.; van den Heuvel, Leigh Luella; Van Hooff, Miranda; Vermetten, Eric; Vinkers, Christiaan H.; Voisey, Joanne; Wang, Yunpeng; Wang, Zhewu; Werge, Thomas; Williams, Michelle A.; Williamson, Douglas E.; Winternitz, Sherry; Wolf, Christiane; Wolf, Erika J.; Yehuda, Rachel; Young, Keith A.; Young, Ross McD; Zhao, Hongyu; Zoellner, Lori A.; Haas, Magali; Lasseter, Heather; Provost, Allison C.; Salem, Rany M.; Sebat, Jonathan; Shaffer, Richard A.; Wu, Tianying; Ripke, Stephan; Daly, Mark J.; Ressler, Kerry J.; Koenen, Karestan C.; Stein, Murray B.; Nievergelt, Caroline M. 分享 收藏 Epigenome-wide meta-analysis of PTSD symptom severity in three military cohorts implicates DNA methylation changes in genes involved in immune system and oxidative stress三个军事队列中PTSD症状严重程度的表观基因组范围荟萃分析涉及免疫系统和氧化应激相关基因的DNA甲基化变化Katrinli, Seyma; Maihofer, Adam X.; Wani, Agaz H.; Pfeiffer, John R.; Ketema, Elizabeth; Ratanatharathorn, Andrew; Baker, Dewleen G.; Boks, Marco P.; Geuze, Elbert; Kessler, Ronald C.; Risbrough, Victoria B.; Rutten, Bart P. F.; Stein, Murray B.; Ursano, Robert J.; Vermetten, Eric; Logue, Mark W.; Nievergelt, Caroline M.; Smith, Alicia K.; Uddin, Monica 分享 收藏 Dysregulated TP53 Among PTSD Patients Leads to Downregulation of miRNA let-7a and Promotes an Inflammatory Th17 PhenotypeBusbee, Philip B.; Bam, Marpe; Yang, Xiaoming; Abdulla, Osama A.; Zhou, Juhua; Ginsberg, Jay Paul (Jack); Aiello, Allison E.; Uddin, Monica; Nagarkatti, Mitzi; Nagarkatti, Prakash S. 分享 收藏 Leukocyte methylomic imprints of exposure to the genocide against the Tutsi in Rwanda: a pilot epigenome-wide analysisMusanabaganwa, Clarisse; Wani, Agaz H.; Donglasan, Janelle; Fatumo, Segun; Jansen, Stefan; Mutabaruka, Jean; Rutembesa, Eugene; Uwineza, Annette; Hermans, Erno J.; Roozendaal, Benno; Wildman, Derek E.; Mutesa, Leon; Uddin, Monica 分享 收藏 
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