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M

Margarida D. Amaral

University of Lisboa

49H指数
313论文数
8.8K被引数
收录论文 100
发表时间
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Combining Gene Therapy with Current Modulator Treatments for Cystic Fibrosis: A Promising Area of Research将基因治疗与囊性纤维化调节剂治疗相结合：一个有前景的研究领域
errPharmaceutics
IF5.5
err2026-08-27
err0
errOAAI
errXavier Buin; Rosy Ghanem; Ines Pankonien; Frédéric Becq; Margarida Amaral; Tristan Montier
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err收藏
A functional comparison of vanzacaftor/tezacaftor/deutivacaftor and elexacaftor/tezacaftor/ivacaftor in patient-derived intestinal organoids with rare CFTR variants功能性比较：在携带罕见CFTR变异的患者源性肠道类器官中，对vanzacaftor/tezacaftor/deutivacaftor和elexacaftor/tezacaftor/ivacaftor的比较
errJournal of Cystic Fibrosis
IF6
err2026-06-16
err0
errOAAI
errSuzanne Kroes; Lara Zaidi; Heleen N. Sonneveld-van Kooten; Lianne Winkel; Kris De Boeck; Margarida Amaral; Cornelis K van der Ent; Jeffrey M. Beekman; Sacha Spelier
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Investigation of HE4 expression concerning epithelial-mesenchymal transition (EMT) in cystic fibrosis epithelial cells关于囊性纤维化上皮细胞中HE4表达与上皮-间质转化（EMT）关系的研究
errJournal of Cystic Fibrosis
IF6
err2026-04-05
err0
errOAAI
errMarianna Pócsi; György Jázon Balla; Ferenc Fenyvesi; Ágnes Rusznyák; Zsolt Fejes; István Balogh; Milan Macek; Margarida D. Amaral; Béla Nagy
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Author’s Reply to Yang and Wang: “Personalized Medicine in Cystic Fibrosis: Characterization of Eight Rare CFTR Variants in Intestinal Organoids and Cellular Models”
errMolecular Diagnosis & Therapy
IF4.4
err2026-01-27
err0
PREAI
errMargarida D. Amaral; Ines Pankonien
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err收藏
Personalized Medicine in Cystic Fibrosis: Characterization of Eight Rare CFTR Variants in Intestinal Organoids and Cellular Models囊性纤维化中的个性化医学：在肠道类器官和细胞模型中对八种罕见CFTR变异的表征
errMolecular Diagnosis & Therapy
IF4.4
err2025-09-13
err0
errOAAI
errVioleta Railean; Cláudia S. Rodrigues; Ines Pankonien; Sofia S. Ramalho; Iris A. L. Silva; Tereza Doušová; Susana Castanhinha; Pilar Azevedo; Juliana Roda; Carlos M. Farinha; Margarida D. Amaral
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Comparison of the Effect of CFTR Modulators elexacaftor/tezacaftor/ivacaftor and lumacaftor/ivacaftor via Serum Human Epididymis Protein 4 Concentration in p.Phe508del-CFTR Homozygous Cystic Fibrosis Patients通过血清人附睾蛋白4浓度比较elexacaftor/tezacaftor/ivacaftor和lumacaftor/ivacaftor对p.Phe508del-CFTR纯合子囊性纤维化患者的影响
errJournal of Clinical Medicine 2025, Vol. 14, Page 6188
IF2.9
err2025-09-04
err0
errOAAI
errMarianna Pócsi; Libor Fila; Csaba Péterfia; Adrien Halász; Tibor G. Szanto; Beáta Mészáros; Judit Major; István Laki; Hajnalka Szabó; György Panyi; István Balogh; Margarida D. Amaral; Milan Macek Jr.; Béla Nagy Jr.
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CFTR ion transport deficiency primes the epithelium for partial epithelial-mesenchymal transition in cystic fibrosisCFTR离子转运缺陷可诱导囊性纤维化中上皮细胞发生部分上皮-间质转化。
errFrontiers in Pharmacology
IF4.8
err2025-08-20
err0
errOAAI
errCláudia S. Rodrigues; Matilde Canto; Raquel Torres; Violeta Railean; Sofia S. Ramalho; Carlos M. Farinha; Ines Pankonien†; Margarida D. Amaral†
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Cystic fibrosis as a paradigmatic disease in bringing science to the bedside囊性纤维化作为将科学带入临床的典范疾病
errFEBS Letters
IF3
err2025-06-26
err0
PREAI
errMargarida D. Amaral; Ines Pankonien
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CyFidb: A Molecular Atlas for Cystic FibrosisCyFidb：囊性纤维化的分子图谱
errJournal of Cystic Fibrosis
IF6
err2025-03-27
err0
errOAAI
errCatarina Pereira; Margarida D. Amaral; Andre O. Falcao
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Personalized therapy with CFTR modulators: Response of p.Ile148Asn variantCFTR调节剂个性化疗法：p.Ile148Asn变异体的应答
errJournal of Cystic Fibrosis
IF6
err2025-02-06
err0
errOAAI
errCláudia S Rodrigues; Violeta Railean; Sofia S Ramalho; Carlos M Farinha; Ines Pankonien; Margarida D Amaral
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Direct access of 4-acyl-1,2,3-triazoles from acetophenones: A synthetic shortcut for novel p.Phe508del-CFTR traffic correctors
errJOURNAL OF MOLECULAR STRUCTURE
IF4.7
err2025-02-01
err1
PREAI
errAzevedo, Marcelo Folhadella M. F.; Zeitune, David C.; de Farias, Renan L.; Eduardo Junior, N. C.; Bacalhau, Mafalda; Amaral, Margarida D.; Lopes-Pacheco, Miqueias; Buarque, Camilla D.
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Theranostics vs theratyping or theranostics plus theratyping?
errJOURNAL OF CYSTIC FIBROSIS
IF6
err2025-01-01
err0
errOAAI
errAmaral, Margarida D.; Pankonien, Ines
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The role of CFTR in the eye, and the effect of early highly effective modulator treatment for cystic fibrosis on eye health
errPROGRESS IN RETINAL AND EYE RESEARCH
IF14.7
err2024-11-01
err0
PREAI
errSchneider-Futschik, Elena K.; Zhu, Yimin; Li, Danni; Habgood, Mark D.; Nguyen, Bao N.; Pankonien, Ines; Amaral, Margarida D.; Downie, Laura E.; Chinnery, Holly R.
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Repeatability and reproducibility of the Forskolin-induced swelling (FIS) assay on intestinal organoids from people with Cystic Fibrosis
errJOURNAL OF CYSTIC FIBROSIS
IF6
err2024-07-01
err4
errOAAI
errBierlaagh, Marlou C.; Ramalho, Anabela S.; Silva, Iris A. L.; Vonk, Annelotte M.; van den Bor, Rutger M.; van Mourik, Peter; Pott, Johanna; Suen, Sylvia W. F.; Boj, Sylvia F.; Vries, Robert G. J.; Lammertyn, Elise; Vermeulen, Francois; Amaral, Margarida D.; de Boeck, Kris; van der Ent, Cornelis K.; Beekman, Jeffrey M.
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PTI-801 (posenacaftor) shares a common mechanism with VX-445 (elexacaftor) to rescue p.Phe508del-CFTR
errEUROPEAN JOURNAL OF PHARMACOLOGY
IF4.7
err2024-03-01
err5
errOAAI
errFerreira, Filipa C.; Amaral, Margarida D.; Bacalhau, Mafalda; Lopes-Pacheco, Miqueias
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Human epididymis protein 4 (HE4) plasma concentration inversely correlates with the improvement of cystic fibrosis lung disease in p.Phe508del-CFTR homozygous cases treated with the CFTR modulator lumacaftor/ivacaftor combination
errJOURNAL OF CYSTIC FIBROSIS
IF6
err2023-11-01
err1
errOAAI
errPocsi, Marianna; Fejes, Zsolt; Bene, Zsolt; Nagy, Attila; Balogh, Istvan; Amaral, Margarida D.; Macek Jr, Milan; Nagy Jr, Bela
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Educational level-dependent melanoma awareness in a high-risk population in Switzerland
errFRONTIERS IN ONCOLOGY
IF3.3
err2023-05-03
err5
errOAAI
errMueller, Alina Miriam; Goessinger, Elisabeth Victoria; Cerminara, Sara Elisa; Kostner, Lisa; Amaral, Margarida; Huber, Stephanie Marie; Passweg, Lea Pauline; Moreno, Laura Garcia; Bodenmann, Daniel; Kunz, Michael; Levesque, Mitchell Paul; Maul, Julia-Tatjana; Cheng, Phil Fang; Navarini, Alexander Andreas; Maul, Lara Valeska
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Antagonistic Regulation of Cystic Fibrosis Transmembrane Conductance Regulator Cell Surface Expression by Protein Kinases WNK4 and Spleen Tyrosine Kinase
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err42
errOAAI
errMendes, Ana Isabel; Matos, Paulo; Moniz, Sonia; Luz, Simao; Amaral, Margarida D.; Farinha, Carlos M.; Jordan, Peter
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Personalized medicine: Function of CFTR variant p.Arg334Trp is rescued by currently available CFTR modulators
errFRONTIERS IN MOLECULAR BIOSCIENCES
IF4
err2023-03-17
err6
errOAAI
errRailean, Violeta; Rodrigues, Claudia S.; Ramalho, Sofia S.; Silva, Iris A. L.; Bartosch, Jan; Farinha, Carlos M.; Pankonien, Ines; Amaral, Margarida D.
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Development of novel therapeutics for all individuals with CF (the future goes on)为所有CF患者开发新的治疗方法 (未来继续)
errJOURNAL OF CYSTIC FIBROSIS
IF6
err2023-03-01
err4
errOAAI
errAmaral, Margarida D.; Harrison, Patrick T.
err分享
err收藏

研究方向

暂无研究方向
合作学者
合作期刊
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