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M

Martijn A. Huynen

Radboud University Nijmegen

81H指数
431论文数
2.2W被引数
收录论文 159
发表时间
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Mucosal immune responses to Bordetella pertussis in Gambian infants after maternal and primary vaccination: an immunological substudy of a single-centre, randomised, controlled, double-blind, phase 4 trial冈比亚婴儿在母体和基础疫苗接种后对百日咳博德特菌的黏膜免疫反应：一项单中心、随机、对照、双盲、IV期试验的免疫学亚组研究
errThe Lancet Microbe
IF0
err2026-01-07
err0
errOAAI
errAnja Saso; Janeri Fröberg; Haddijatou Jobe; Marc Eleveld; Michael Okoye; Ebrima Kanteh; Annemijn Arns; Fred van Opzeeland; Michelle Kumado; Amadou Faal; Elishia Roberts; Modou-Lamin Fofana; Aru-Kumba Baldeh; Karamo Conteh; Bram van Cranenbroek; Sophie Roetynck; Marien de Jonge; Thushan I de Silva; Martijn Huynen; Beate Kampmann
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err收藏
Functional characterization of a human epilepsy-associated gene network reveals metabolic regulation as a critical factor underlying seizure susceptibilities人类癫痫相关基因网络的功能表征揭示代谢调控是癫痫易感性的关键因素
errDisease Models & Mechanisms
IF3.3
err2026-01-01
err0
errOAAI
errLong, Jingyi; Jones, Spencer G.; Serna, Ana; van Reijmersdal, Boyd; Kampshoff, Franziska; Aibar, Sara; Verstreken, Patrik; Huynen, Martijn A.; Coll-Tane, Mireia; Schenck, Annette
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A recurrent adaptive mutation in the transmembrane 2B protein of an insect picorna-like virus in a nonnative host一种昆虫picorna-like病毒在非宿主中的跨膜2B蛋白的复现适应性突变
errJournal of Virology
IF3.8
err2025-12-01
err0
PREAI
errLezcano, Oscar M.; Fuhrmann, Lara; Bos, Reinder T.; Wang, Haitao; Stevens, Milou; Beerenwinkel, Niko; Huynen, Martijn A.; van Rij, Ronald P.
err分享
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Chromosome-scale genome assembly and gene annotation of the hydrothermal vent annelid Alvinella pompejana yield insight into animal evolution in extreme environments染色体水平基因组组装和基因注释揭示了极端环境中的动物进化，该研究以热液喷口环节动物Alvinella pompejana为研究对象。
errBMC Biology
IF4.5
err2025-10-03
err0
errOAAI
errSami El Hilali; Philippe Dru; Alan Le Moan; Yang I Li; Martijn A. Huynen; André Hoelz; Robert C. Robinson; José M. Martín-Durán; Didier Jollivet; Adam Claridge-Chang; Richard R. Copley
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Mesenchymal stem cells suppress NF-κB and ERK signalling while enhancing chemotaxis in CD4+ T cells间充质干细胞抑制CD4+ T细胞中NF-κB和ERK信号通路，同时增强其趋化性。
errScientific Reports
IF3.9
err2025-08-30
err0
errOAAI
errEzgi Sengun; Janeri Fröberg; Xuehui He; Marc Eleveld; Ruben L. Smeets; Hans J. P. M. Koenen; Katja Möller-Hackbarth; Tim G. A. M. Wolfs; Daan R. M. G. Ophelders; Martijn A. Huynen; Marien I. de Jonge; Renate G. van der Molen
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The use of knowledge graphs for drug repurposing: From classical machine learning algorithms to graph neural networks使用知识图进行药物再利用: 从经典的机器学习算法到图形神经网络
errComputers in Biology and Medicine
IF6.3
err2025-08-09
err0
errOAAI
errSiqi Wei; Christo Sasi; Jelle Piepenbrock; Martijn A. Huynen; Peter A.C. ’t Hoen
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Exome variant prioritization in a large cohort of hearing-impaired individuals indicates IKZF2 to be associated with non-syndromic hearing loss and guides future research of unsolved cases在一大批听力受损人群中，外显子组变体优先排序表明IKZF2与非综合征性听力损失有关，并指导未解决病例的未来研究
errHUMAN GENETICS
IF3.6
err2024-10-16
err1
errOAAI
errVelde, Hedwig M.; Vaseghi-Shanjani, Maryam; Smits, Jeroen J.; Ramakrishnan, Gayatri; Oostrik, Jaap; Wesdorp, Mieke; Astuti, Galuh; Yntema, Helger G.; Hoefsloot, Lies; Lanting, Cris P.; Huynen, Martijn A.; Lehman, Anna; Turvey, Stuart E.; Pennings, Ronald J. E.; Kremer, Hannie
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Structural basis of LRPPRC-SLIRP-dependent translation by the mitoribosome (Aug, 10.1038/s41594-024-01365-9, 2024)
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2024-09-19
err0
errOAAI
errSingh, Vivek; Moran, J. Conor; Itoh, Yuzuru; Soto, Iliana C.; Fontanesi, Flavia; Couvillion, Mary; Huynen, Martijn A.; Churchman, L. Stirling; Barrientos, Antoni; Amunts, Alexey
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Analysis of Complexome Profiles with the Gaussian Interaction Profiler (GIP) Reveals Novel Protein Complexes in Plasmodium falciparum
errJOURNAL OF PROTEOME RESEARCH
IF3.6
err2024-09-12
err0
errOAAI
errvan Strien, Joeri; Evers, Felix; Cabrera-Orefice, Alfredo; Delhez, Iris; Kooij, Taco W. A.; Huynen, Martijn A.
err分享
err收藏
Structural basis of LRPPRC-SLIRP-dependent translation by the mitoribosome线粒体体依赖lrpprc-slirp翻译的结构基础
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2024-08-12
err1
errOAAI
errSingh, Vivek; Moran, J. Conor; Itoh, Yuzuru; Soto, Iliana C.; Fontanesi, Flavia; Couvillion, Mary; Huynen, Martijn A.; Churchman, L. Stirling; Barrientos, Antoni; Amunts, Alexey
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Temporal composition of the cervicovaginal microbiome associates with hrHPV infection outcomes in a longitudinal study
errBMC INFECTIOUS DISEASES
IF3
err2024-06-03
err3
errOAAI
errMolina, Mariano A.; Leenders, William P. J.; Huynen, Martijn A.; Melchers, Willem J. G.; Andralojc, Karolina M.
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err收藏
Effect of age and season on respiratory mucosal immune marker profiles
errJOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
IF11.2
err2024-06-01
err1
PREAI
errvan Woudenbergh, Esther; van Rooijen, Debbie M.; Veldman-Wolf, Janine J.; Nicolaie, Mioara A.; Huynen, Martijn A.; van der Klis, Fiona R. M.; de Jonge, Marien I.; den Hartog, Gerco
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Antiviral responses induced by Tdap-IPV vaccination are associated with persistent humoral immunity to Bordetella pertussis
errNATURE COMMUNICATIONS
IF15.7
err2024-03-08
err2
errOAAI
errGillard, Joshua; Suffiotti, Madeleine; Brazda, Peter; Venkatasubramanian, Prashanna B.; Versteegen, Pauline; de Jonge, Marien I.; Kelly, Dominic; Bibi, Sagida; Pinto, Marta Valente; Simonetti, Elles; Babiceanu, Mihaela; Kettring, Andrew; Teodosio, Cristina; de Groot, Ronald; Berbers, Guy; Stunnenberg, Hendrik G.; Schanen, Brian; Fenwick, Craig; Huynen, Martijn A.; Diavatopoulos, Dimitri A.
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Parallel evolution and enhanced virulence upon in vivo passage of an RNA virus in Drosophila melanogaster
errVIRUS EVOLUTION
IF4
err2023-12-15
err2
errOAAI
errLezcano, Oscar M.; Fuhrmann, Lara; Ramakrishnan, Gayatri; Beerenwinkel, Niko; Huynen, Martijn A.; van Rij, Ronald P.
err分享
err收藏
Primary Exposure to SARS-CoV-2 via Infection or Vaccination Determines Mucosal Antibody-Dependent ACE2 Binding Inhibition
errJOURNAL OF INFECTIOUS DISEASES
IF4.5
err2023-09-07
err3
errOAAI
errFroberg, Janeri; Koomen, Vera J. C. H.; van der Gaast-de Jongh, Christa E.; Philipsen, Ria; Geurtsvankessel, Corine H.; de Vries, Rory D.; Baas, Marije C.; van der Molen, Renate G.; de Jonge, Marien, I; Hilbrands, Luuk B.; Huynen, Martijn A.; Diavatopoulos, Dimitri A.
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Understanding structure-guided variant effect predictions using 3D convolutional neural networks
errFRONTIERS IN MOLECULAR BIOSCIENCES
IF4
err2023-07-05
err4
errOAAI
errRamakrishnan, Gayatri; Baakman, Coos; Heijl, Stephan; Vroling, Bas; van Horck, Ragna; Hiraki, Jeffrey; Xue, Li C.; Huynen, Martijn A.
err分享
err收藏
Prior exposure to B. pertussis shapes the mucosal antibody response to acellular pertussis booster vaccination
errNATURE COMMUNICATIONS
IF15.7
err2022-12-02
err4
errOAAI
errvan Schuppen, Evi; Froberg, Janeri; Venkatasubramanian, Prashanna Balaji; Versteegen, Pauline; de Graaf, Hans; Holubova, Jana; Gillard, Joshua; van Gageldonk, Pieter G. M.; Joosten, Irma; de Groot, Ronald; Sebo, Peter; Berbers, Guy A. M.; Read, Robert C.; Huynen, Martijn A.; de Jonge, Marien, I; Diavatopoulos, Dimitri A.
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Assessing the Cervicovaginal Microbiota in the Context of hrHPV Infections: Temporal Dynamics and Therapeutic Strategies在hrHPV感染的背景下评估宫颈阴道微生物群: 时间动力学和治疗策略
errMBIO
IF4.7
err2022-10-26
err5
errOAAI
errMolina, Mariano A.; Coenen, Britt A.; Leenders, William P. J.; Andralojc, Karolina M.; Huynen, Martijn A.; Melchers, Willem J. G.
err分享
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In-depth insights into cervicovaginal microbial communities and hrHPV infections using high-resolution microbiome profiling使用高分辨率微生物组分析深入了解宫颈阴道微生物群落和hrHPV感染
errNPJ BIOFILMS AND MICROBIOMES
IF9.2
err2022-09-28
err11
errOAAI
errMolina, Mariano A.; Andralojc, Karolina M.; Huynen, Martijn A.; Leenders, William P. J.; Melchers, Willem J. G.
err分享
err收藏
Structural and functional comparison of magnesium transporters throughout evolution镁转运蛋白在整个进化过程中的结构和功能比较
errCELLULAR AND MOLECULAR LIFE SCIENCES
IF6.2
err2022-07-12
err30
errOAAI
errFranken, G. A. C.; Huynen, M. A.; Martinez-Cruz, L. A.; Bindels, R. J. M.; de Baaij, J. H. F.
err分享
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研究方向

暂无研究方向
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