未登录 EphA2-targeting bicycle toxin conjugate (BTC) BT5528 in patients (pts) with advanced solid tumors: A phase I/II study EphA2靶向环形分子毒素偶联物（BTC）BT5528在晚期实体瘤患者（pts）中的I/II期研究 Fontana, E.; Wang, J. S.; Mckean, M.; Aljumaily, R.; Machiels, J-P.; Doger de Speville, B.; Vieito, M.; Carter, L.; Prenen, H.; Falchook, G. S.; Greystoke, A.; Feliu, W. I. Ortuzar; De, A.; Gu, X.; Li, M.; de Rienzo, A.; Bashir, B. 分享 收藏
Characterization of Nectin-4 protein expression in non-small cell lung cancer patients Santos, Sean M.; Darlington, Emma; Woodhouse, Laura; Peters, Niamh; Peat, Erin; De Rienzo, Assunta; Smale, Rob; Watson, Shawn; Blakemore, Stephen; Carter, Louise; Campbell, Carly 分享 收藏
Trial in progress: First-in-human phase I dose-escalation study of a novel Bicycle toxin conjugate (BT5528) targeting EphA2 in patients with advanced solid tumors Fontana, Elisa; Bashir, Babar; Wang, Judy S.; Aljumaily, Raid; Machiels, Jean-Pascal; Vieito, Maria; Falchook, Gerald; Carter, Louise; de Speville, Bernard Doger; Greystoke, Alastair; Kim, Sang Wun; Kotecki, Nuria; Spira, Alexander I.; Candilejo, Irene Moreno; Basu, Bristi; Prenen, Hans; Bessudo, Alberto; Nagasaka, Misako; Ahnert, Jordi Rodon; Park, Joo-Hwan; Teo, Min-Yuen; Rotow, Julia; Liu, Jie; De Rienzo, Assunta; Li, Mengyao; Domingo, Adriana; Orr, Hanna; Bennett, Gavin; Sharma, Rajiv; McKean, Meredith 分享 收藏
Uncommitted cells and phenotypic plasticity elucidate the complexity of the epithelial-mesenchymal molecular gradient of pleural mesothelioma Severson, David T.; Freyaldenhoven, Samuel; Wadowski, Benjamin; Hughes, Travis; Hung, Yin P.; Jensen, Roderick V.; Richards, William G.; Gustafson, Corinne E.; Vermilya, Kimberly; Innocenti, Simona; Barlow, Julianne S.; Cougar, Matthew B.; Anderson, Jamie; Wang, Vivian; Dao, Mary N.; Shalek, Alex K.; De Rienzo, Assunta; Bueno, Raphael 分享 收藏
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Identification of a targetable KRAS-mutant epithelial population in non-small cell lung cancer Maroni, Giorgia; Bassal, Mahmoud A.; Krishnan, Indira; Fhu, Chee Wai; Savova, Virginia; Zilionis, Rapolas; Maymi, Valerie A.; Pandell, Nicole; Csizmadia, Eva; Zhang, Junyan; Storti, Barbara; Castano, Julio; Panella, Riccardo; Li, Jia; Gustafson, Corinne E.; Fox, Sam; Levy, Rachel D.; Meyerovitz, Claire, V; Tramontozzi, Peter J.; Vermilya, Kimberly; De Rienzo, Assunta; Crucitta, Stefania; Basseres, Daniela S.; Weetall, Marla; Branstrom, Art; Giorgetti, Alessandra; Ciampi, Raffaele; Del Re, Marzia; Danesi, Romano; Bizzarri, Ranieri; Yang, Henry; Kocher, Olivier; Klein, Allon M.; Welner, Robert S.; Bueno, Raphael; Magli, Maria Cristina; Clohessy, John G.; Ali, Azhar; Tenen, Daniel G.; Levantini, Elena 分享 收藏
Large-scale analysis ofBAP1expression reveals novel associations with clinical and molecular features of malignant pleural mesothelioma De Rienzo, Assunta; Chirieac, Lucian R.; Hung, Yin P.; Severson, David T.; Freyaldenhoven, Samuel; Gustafson, Corinne E.; Dao, Nhien T.; Meyerovitz, Claire, V; Oster, Michela E.; Jensen, Roderick, V; Yeap, Beow Y.; Bueno, Raphael; Richards, William G. 分享 收藏
Single-Cell Transcriptomics of Human and Mouse Lung Cancers Reveals Conserved Myeloid Populations across Individuals and Species 人类和小鼠肺癌的单细胞转录组学揭示了跨个人和物种的保守骨髓群 Zilionis, Rapolas; Engblom, Camilla; Pfirschke, Christina; Savova, Virginia; Zemmour, David; Saatcioglu, Hatice D.; Krishnan, Indira; Maroni, Giorgia; Meyerovitz, Claire V.; Kerwin, Clara M.; Choi, Sun; Richards, William G.; De Rienzo, Assunta; Tenen, Daniel G.; Bueno, Raphael; Levantini, Elena; Pittet, Mikael J.; Klein, Allon M. 分享 收藏
Antigen identification for cancer immunotherapy by deep learning on tumor HLA peptides Bulik-Sullivan, Brendan; Busby, Jennifer; Davis, Matthew; Young, Lauren; Murphy, Tyler; Clark, Andrew; Duke, Fujiko; Busby, Michele; Derti, Adnan; Skoberne, Mojca; Jooss, Karin; Gustafson, Corinne E.; De Rienzo, Assunta; Richards, William G.; Dao, Nhien T.; Kim, Hyeong R.; Anderson, Jamie E.; Choi, Chang-Min; De Montpreville, Vincent; Jang, Se Jin; Mercier, Olaf; Bueno, Raphael; Fadel, Elie; Francis, Joshua; Yelensky, Roman 分享 收藏
Validation of a Gene Expression Test for Mesothelioma Prognosis in Formalin-Fixed Paraffin-Embedded Tissues De Rienzo, Assunta; Cook, Robert W.; Wilkinson, Jeff; Gustafson, Corinne E.; Amin, Waqas; Johnson, Clare E.; Oelschlager, Kristen M.; MaetzoLd, Derek J.; Stone, John F.; Feldman, Michael D.; Becich, Michael J.; Yeap, Beow Y.; Richards, William G.; Bueno, Raphael 分享 收藏
Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations Seshagiri, Somasekar; Stawiski, Eric; Goldstein, Leonard; Durinck, Steffen; Modrusan, Zora; Gnad, Florian; Nguyen, Thong T.; Jaiswal, Bijay; De Rienzo, Assunta; Richards, William; Bueno, Raphael 分享 收藏
Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations Bueno, Raphael; Stawiski, Eric W.; Goldstein, Leonard D.; Durinck, Steffen; De Rienzo, Assunta; Modrusan, Zora; Gnad, Florian; Nguyen, Thong T.; Jaiswal, Bijay S.; Chirieac, Lucian R.; Sciaranghella, Daniele; Dao, Nhien; Gustafson, Corinne E.; Munir, Kiara J.; Hackney, Jason A.; Chaudhuri, Amitabha; Gupta, Ravi; Guillory, Joseph; Toy, Karen; Ha, Connie; Chen, Ying-Jiun; Stinson, Jeremy; Chaudhuri, Subhra; Zhang, Na; Wu, Thomas D.; Sugarbaker, David J.; de Sauvage, Frederic J.; Richards, William G.; Seshagiri, Somasekar 分享 收藏
Gender-Specific Molecular and Clinical Features Underlie Malignant Pleural Mesothelioma De Rienzo, Assunta; Archer, Michael A.; Yeap, Beow Y.; Dao, Nhien; Sciaranghella, Daniele; Sideris, Antonios C.; Zheng, Yifan; Holman, Alexander G.; Wang, Yaoyu E.; Dal Cin, Paola S.; Fletcher, Jonathan A.; Rubio, Renee; Croft, Larry; Quackenbush, John; Sugarbaker, Peter E.; Munir, Kiara J.; Battilana, Jesse R.; Gustafson, Corinne E.; Chirieac, Lucian R.; Ching, Soo Meng; Wong, James; Tay, Liang Chung; Rudd, Stephen; Hercus, Robert; Sugarbaker, David J.; Richards, William G.; Bueno, Raphael 分享 收藏
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Transcriptome sequencing of malignant pleural mesothelioma tumors Sugarbaker, David J.; Richards, William G.; Gordon, Gavin J.; Dong, Lingsheng; De Rienzo, Assunta; Maulik, Gautam; Glickman, Jonathan N.; Chirieac, Lucian R.; Hartman, Mor-Li; Taillon, Bruce E.; Du, Lei; Bouffard, Pascal; Kingsmore, Stephen F.; Miller, Neil A.; Farmer, Andrew D.; Jensen, Roderick V.; Gullans, Steven R.; Bueno, Raphael 分享 收藏
RETRACTED: Potentiation of paclitaxel activity by the HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin in human ovarian carcinoma cell lines with high levels of activated AKT (Retracted article. See vol. 17, pg. 2075, 2018) Sain, Nivedita; Krishnan, Bhavani; Ormerod, Michael G.; De Rienzo, Assunta; Liu, Wai M.; Kaye, Stanley B.; Workman, Paul; Jackman, Ann L. 分享 收藏
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Human and mouse mesotheliomas exhibit elevated AKT/PKB activity, which can be targeted pharmacologically to inhibit tumor cell growth Altomare, DA; You, HH; Xiao, GH; Ramos-Nino, ME; Skele, KL; De Rienzo, A; Jhanwar, SC; Mossman, BT; Kane, AB; Testa, JR 分享 收藏
Replacement of K-Ras with H-Ras supports normal embryonic development despite inducing cardiovascular pathology in adult mice Potenza, N; Vecchione, C; Notte, A; De Rienzo, A; Rosica, A; Bauer, L; Affuso, A; De Felice, M; Russo, T; Poulet, R; Cifelli, G; De Vita, G; Lembo, G; Di Lauro, R 分享 收藏
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