Gaoxingyu Huang - Publications, H-index & Citations

Gaoxingyu Huang

Westlake Laboratory of Life Science and Biomedicine

28H指数

50论文数

3.3K被引数

收录论文 20

发表时间

Structural basis of BAX pore formation BAX孔形成结构基础

Science

IF45.8

2025-06-26

PREAI

Ying Zhang; Lu Tian; Gaoxingyu Huang; Xiaofei Ge; Fang Kong; Pengqi Wang; Yige Xu; Yigong Shi

De novo design of transmembrane fluorescence-activating proteins 从头设计跨膜荧光激活蛋白

NATURE

IF48.5

2025-02-19

PREAI

Zhu, Jingyi; Liang, Mingfu; Sun, Ke; Wei, Yu; Guo, Ruiying; Zhang, Lijing; Shi, Junhui; Ma, Dan; Hu, Qi; Huang, Gaoxingyu; Lu, Peilong

CryoSeek: A strategy for bioentity discovery using cryoelectron microscopy

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-10-09

PREAI

Wang, Tongtong; Li, Zhangqiang; Xu, Kui; Huang, Wenze; Huang, Gaoxingyu; Zhang, Qiangfeng Cliff; Yan, Nieng

Structural basis for urate recognition and apigenin inhibition of human GLUT9

NATURE COMMUNICATIONS

IF15.7

2024-06-12

OAAI

Shen, Zilin; Xu, Li; Wu, Tong; Wang, Huan; Wang, Qifan; Ge, Xiaofei; Kong, Fang; Huang, Gaoxingyu; Pan, Xiaojing

Cryo-EM structures of apo and antagonist-bound human Cav3.1 (vol 576, pg 492, 2019)Cryo-EM结构：人源Cav3.1的 apo 状态和拮抗剂结合状态（vol 576, pg 492, 2019）

NATURE

IF48.5

2024-05-29

OAAI

Zhao, Yanyu; Huang, Gaoxingyu; Wu, Qiurong; Wu, Kun; Li, Ruiqi; Lei, Jianlin; Pan, Xiaojing; Yan, Nieng

Dissection of the structure-function relationship of Nav channels

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-02-21

OAAI

Li, Zhangqiang; Wu, Qiurong; Huang, Gaoxingyu; Jin, Xueqin; Li, Jiaao; Pan, Xiaojing; Yan, Nieng

Structure of the nuclear pore complex atomic

CURRENT OPINION IN STRUCTURAL BIOLOGY

IF7

2023-02-01

PREAI

Huang, Gaoxingyu; Zeng, Chao; Shi, Yigong

LilrB3 is a putative cell surface receptor of APOE4

CELL RESEARCH

IF25.9

2023-01-02

OAAI

Zhou, Jiayao; Wang, Yumeng; Huang, Gaoxingyu; Yang, Min; Zhu, Yumin; Jin, Chen; Jing, Dan; Ji, Kai; Shi, Yigong

Unwinding and spiral sliding of S4 and domain rotation of VSD during the electromechanical coupling in Nav1.7

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-07-25

OAAI

Huang, Gaoxingyu; Wu, Qiurong; Li, Zhangqiang; Jin, Xueqin; Huang, Xiaoshuang; Wu, Tong; Pan, Xiaojing; Yan, Nieng

Structural basis for high-voltage activation and subtype-specific inhibition of human Nav1.8 人Nav1.8的高电压激活和亚型特异性抑制的结构基础

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-07-19

OAAI

Huang, Xiaoshuang; Jin, Xueqin; Huang, Gaoxingyu; Huang, Jian; Wu, Tong; Li, Zhangqiang; Chen, Jiaofeng; Kong, Fang; Pan, Xiaojing; Yan, Nieng

High-resolution structures of human Nav1.7 reveal gating modulation through α-π helical transition of S6IV

CELL REPORTS

IF6.9

2022-04-01

OAAI

Huang, Gaoxingyu; Liu, Dongliang; Wang, Weipeng; Wu, Qiurong; Chen, Jiaofeng; Pan, Xiaojing; Shen, Huaizong; Yan, Nieng

Cryo-EM structure of the inner ring from the Xenopus laevis nuclear pore complex

CELL RESEARCH

IF25.9

2022-03-18

OAAI

Huang, Gaoxingyu; Zhan, Xiechao; Zeng, Chao; Liang, Ke; Zhu, Xuechen; Zhao, Yanyu; Wang, Pan; Wang, Qifan; Zhou, Qiang; Tao, Qinghua; Liu, Minhao; Lei, Jianlin; Yan, Chuangye; Shi, Yigong

Cryo-EM structure of the nuclear ring from Xenopus laevis nuclear pore complex

CELL RESEARCH

IF25.9

2022-02-17

OAAI

Huang, Gaoxingyu; Zhan, Xiechao; Zeng, Chao; Zhu, Xuechen; Liang, Ke; Zhao, Yanyu; Wang, Pan; Wang, Qifan; Zhou, Qiang; Tao, Qinghua; Liu, Minhao; Lei, Jianlin; Yan, Chuangye; Shi, Yigong

Cryo-EM structure of human Wntless in complex with Wnt3a

NATURE COMMUNICATIONS

IF15.7

2021-07-27

OAAI

Zhong, Qing; Zhao, Yanyu; Ye, Fangfei; Xiao, Zaiyu; Huang, Gaoxingyu; Xu, Meng; Zhang, Yuanyuan; Zhan, Xiechao; Sun, Ke; Wang, Zhizhi; Cheng, Shanshan; Feng, Shan; Zhao, Xiuxiu; Zhang, Jizhong; Lu, Peilong; Xu, Wenqing; Zhou, Qiang; Ma, Dan

Structural Basis for Pore Blockade of the Human Cardiac Sodium Channel Nav1.5 by the Antiarrhythmic Drug Quinidine**

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2021-04-06

OAAI

Li, Zhangqiang; Jin, Xueqin; Wu, Tong; Huang, Gaoxingyu; Wu, Kun; Lei, Jianlin; Pan, Xiaojing; Yan, Nieng

Comparative structural analysis of human Nav1.1 and Nav1.5 reveals mutational hotspots for sodium channelopathies

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-03-12

OAAI

Pan, Xiaojing; Li, Zhangqiang; Jin, Xueqin; Zhao, Yanyu; Huang, Gaoxingyu; Huang, Xiaoshuang; Shen, Zilin; Cao, Yong; Dong, Mengqiu; Lei, Jianlin; Yan, Nieng

Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex by cryo-electron microscopy single particle analysis

CELL RESEARCH

IF25.9

2020-05-06

OAAI

Huang, Gaoxingyu; Zhang, Yanqing; Zhu, Xuechen; Zeng, Chao; Wang, Qifan; Zhou, Qiang; Tao, Qinghua; Liu, Minhao; Lei, Jianlin; Yan, Chuangye; Shi, Yigong

Molecular architecture of the luminal ring of the Xenopus laevis nuclear pore complex

CELL RESEARCH

IF25.9

2020-05-04

OAAI

Zhang, Yanqing; Li, Sai; Zeng, Chao; Huang, Gaoxingyu; Zhu, Xuechen; Wang, Qifan; Wang, Kunpeng; Zhou, Qiang; Yan, Chuangye; Zhang, Wusheng; Yang, Guangwen; Liu, Minhao; Tao, Qinghua; Lei, Jianlin; Shi, Yigong

Molecular basis for allosteric regulation of the type 2 ryanodine receptor channel gating by key modulators

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-12-02

OAAI

Chi, Ximin; Gong, Deshun; Ren, Kang; Zhou, Gewei; Huang, Gaoxingyu; Lei, Jianlin; Zhou, Qiang; Yan, Nieng

Structure of the human plasma membrane Ca2+-ATPase 1 in complex with its obligatory subunit neuroplastin

NATURE COMMUNICATIONS

IF15.7

2018-09-06

OAAI

Gong, Deshun; Chi, Ximin; Ren, Kang; Huang, Gaoxingyu; Zhou, Gewei; Yan, Nieng; Lei, Jianlin; Zhou, Qiang

研究方向