Rik K. Wierenga - Publications, H-index & Citations

Rik K. Wierenga

University of Oulu

52H指数

192论文数

1.0W被引数

收录论文 52

发表时间

Binding Differences of the Peptide-Substrate-Binding Domain of Collagen Prolyl 4-Hydroxylases I and II for Proline- and Hydroxyproline-Rich Peptides I型和II型胶原蛋白脯氨酰4-羟化酶的肽-底物结合域对富含脯氨酸和羟脯氨酸的肽的结合差异

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2025-05-19

OAAI

M. Mubinur Rahman; Ramita Sulu; Bukunmi Adediran; Hongmin Tu; Antti M. Salo; Sudarshan Murthy; Johanna Myllyharju; Rik K. Wierenga; M. Kristian Koski

obituary Jan Drenth (1925-2025)讣告 Jan Drenth (1925-2025)

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY

IF3.8

2025-04-01

PREAI

Dijkstra, BW; Wierenga, RK; Schierbeek, AJ; Hol, WGJ

Enzymes of the crotonase superfamily: Diverse assembly and diverse function

CURRENT OPINION IN STRUCTURAL BIOLOGY

IF7

2023-10-01

OAAI

Dalwani, Subhadra; Wierenga, Rik K.

Thiolase: A Versatile Biocatalyst Employing Coenzyme A-Thioester Chemistry for Making and Breaking C-C Bonds

ANNUAL REVIEW OF BIOCHEMISTRY

IF20.5

2023-06-20

OAAI

Harijan, Rajesh K.; Dalwani, Subhadra; Kiema, Tiila-Riikka; Venkatesan, Rajaram; Wierenga, Rik K.

An engineered variant of MECR reductase reveals indispensability of long-chain acyl-ACPs for mitochondrial respiration

NATURE COMMUNICATIONS

IF15.7

2023-02-04

OAAI

Tanvir Rahman, M.; Kristian Koski, M.; Panecka-Hofman, Joanna; Schmitz, Werner; Kastaniotis, Alexander J.; Wade, Rebecca C.; Wierenga, Rik K.; Kalervo Hiltunen, J.; Autio, Kaija J.

Crystal structure of the collagen prolyl 4-hydroxylase (C-P4H) catalytic domain complexed with PDI: Toward a model of the C-P4H α2β2 tetramer

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-12-01

OAAI

Murthy, Abhinandan V.; Sulu, Ramita; Lebedev, Andrey; Salo, Antti M.; Korhonen, Kati; Venkatesan, Rajaram; Tu, Hongmin; Bergmann, Ulrich; Janis, Janne; Laitaoja, Mikko; Ruddock, Lloyd W.; Myllyharju, Johanna; Koski, M. Kristian; Wierenga, Rik K.

Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis β-oxidation trifunctional enzyme

JOURNAL OF STRUCTURAL BIOLOGY

IF5.1

2021-09-01

OAAI

Dalwani, Subhadra; Lampela, Outi; Leprovost, Pierre; Schmitz, Werner; Juffer, Andre H.; Wierenga, Rik K.; Venkatesan, Rajaram

Structure of transmembrane prolyl 4-hydroxylase reveals unique organization of EF and dioxygenase domains

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-01-01

OAAI

Myllykoski, Matti; Sutinen, Aleksi; Koski, M. Kristian; Kallio, Juha P.; Raasakka, Arne; Myllyharju, Johanna; Wierenga, Rik K.; Koivunen, Peppi

Insights into the stability and substrate specificity of the E. coli aerobic β-oxidation trifunctional enzyme complex

JOURNAL OF STRUCTURAL BIOLOGY

IF5.1

2020-06-01

OAAI

Sah-Teli, Shiv Kumar; Hynonen, Mikko; Sulu, Ramita; Dalwani, Subhadra; Schmitz, Werner; Wierenga, Rik; Venkatesan, Rajaram

Complementary substrate specificity and distinct quaternary assembly of the Escherichia coli aerobic and anaerobic β-oxidation trifunctional enzyme complexes

BIOCHEMICAL JOURNAL

IF4.3

2019-07-15

OAAI

Sah-Teli, Shiv K.; Hynonen, Mikko J.; Schmitz, Werner; Geraets, James A.; Seitsonen, Jani; Pedersen, Jan Skov; Butcher, Sarah J.; Wierenga, Rik K.; Venkatesan, Rajaram

The peroxisomal zebrafish SCP2-thiolase (type-1) is a weak transient dimer as revealed by crystal structures and native mass spectrometry

BIOCHEMICAL JOURNAL

IF4.3

2019-01-25

OAAI

Kiema, Tiila-Riikka; Thapa, Chandan J.; Laitaoja, Mikko; Schmitz, Werner; Maksimainen, Mirko M.; Fukao, Toshiyuki; Rouvinen, Juha; Janis, Janne; Wierenga, Rik K.

De novo biosynthesis of sterols and fatty acids in the Trypanosoma brucei procyclic form: Carbon source preferences and metabolic flux redistributions

PLOS PATHOGENS

IF4.9

2018-05-29

OAAI

Millerioux, Yoann; Mazet, Muriel; Bouyssou, Guillaume; Allmann, Stefan; Kiema, Tiila-Riikka; Bertiaux, Eloise; Fouillen, Laetitia; Thapa, Chandan; Biran, Marc; Plazolles, Nicolas; Dittrich-Domergue, Franziska; Crouzols, Aline; Wierenga, Rik K.; Rotureau, Brice; Moreau, Patrick; Bringaud, Frederic

Assembly of the elongated collagen prolyl 4-hydroxylase α2β2 heterotetramer around a central α2 dimer

BIOCHEMICAL JOURNAL

IF4.3

2017-02-20

OAAI

Koski, M. Kristian; Anantharajan, Jothi; Kursula, Petri; Dhavala, Prathusha; Murthy, Abhinandan V.; Bergmann, Ulrich; Myllyharju, Johanna; Wierenga, Rik K.

The SCP2-thiolase-like protein (SLP) of Trypanosoma brucei is an enzyme involved in lipid metabolism 布氏锥虫的SCP2-thiolase-like蛋白 (SLP) 是一种参与脂质代谢的酶

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2016-05-09

OAAI

Harijan, Rajesh K.; Mazet, Muriel; Kiema, Tiila R.; Bouyssou, Guillaume; Alexson, Stefan E. H.; Bergmann, Ulrich; Moreau, Patrick; Michels, Paul A. M.; Bringaud, Frederic; Wierenga, Rik K.

Human Δ3,Δ2-enoyl-CoA isomerase, type 2: a structural enzymology study on the catalytic role of its ACBP domain and helix-10

FEBS JOURNAL

IF4.2

2015-01-14

OAAI

Onwukwe, Goodluck U.; Kursula, Petri; Koski, M. Kristian; Schmitz, Werner; Wierenga, Rik K.

Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase

NATURE COMMUNICATIONS

IF15.7

2014-09-09

OAAI

Venkatesan, Rajaram; Sah-Teli, Shiv K.; Awoniyi, Luqman O.; Jiang, Guangyu; Prus, Piotr; Kastaniotis, Alexander J.; Hiltunen, J. Kalervo; Wierenga, Rik K.; Chen, Zhijun

Crystal structures of SCP2-thiolases of Trypanosomatidae, human pathogens causing widespread tropical diseases: the importance for catalysis of the cysteine of the unique HDCF loop

BIOCHEMICAL JOURNAL

IF4.3

2013-09-13

PREAI

Harijan, Rajesh K.; Kiema, Tiila R.; Karjalainen, Mikael P.; Janardan, Neelanjana; Murthy, M. R. N.; Weiss, Manfred S.; Michels, Paul A. M.; Wierenga, Rik K.

Structure of Mycobacterial β-Oxidation Trifunctional Enzyme Reveals Its Altered Assembly and Putative Substrate Channeling Pathway

ACS CHEMICAL BIOLOGY

IF3.8

2013-03-27

PREAI

Venkatesan, Rajaram; Wierenga, Rik K.

The isomerase and hydratase reaction mechanism of the crotonase active site of the multifunctional enzyme (type-1), as deduced from structures of complexes with 3S-hydroxy-acyl-CoA

FEBS JOURNAL

IF4.2

2013-02-15

OAAI

Kasaragod, Prasad; Schmitz, Werner; Hiltunen, Jukka K.; Wierenga, Rik K.

The characterization and evolutionary relationships of a trypanosomal thiolase

INTERNATIONAL JOURNAL FOR PARASITOLOGY

IF3.2

2011-10-01

PREAI

Mazet, Muriel; Harijan, Rajesh K.; Kiema, Tiila-Riika; Haapalainen, Antti M.; Morand, Pauline; Morales, Jorge; Bringaud, Frederic; Wierenga, Rik K.; Michels, Paul A. M.

研究方向