C.M. Dunham - Publications, H-index & Citations

C.M. Dunham

emory university

31H指数

182论文数

4.5K被引数

收录论文 48

发表时间

Ribosomal protein bL27 protects translating ribosomes from tmRNA-SmpB 核糖体蛋白bL27保护翻译中的核糖体免受tmRNA-SmpB的影响

Science Advances

IF12.5

2026-08-07

OAAI

Divyasorubini Seerpatham; George Wanes; Chathuri Pathirage; Mynthia Cabrera; Edu Usoro; Kristin S. Koutmou; Christine M. Dunham; Paul C. Whitford; Kenneth C. Keiler

An RNA modification prevents extended codon-anticodon interactions from facilitating +1 frameshifting 一种RNA修饰可阻止扩展的密码子-反密码子相互作用促进+1移码。

Nature Communications

IF15.7

2025-08-11

OAAI

Evelyn M. Kimbrough; Ha An Nguyen; Haixing Li; Jacob M. Mattingly; Nevette A. Bailey; Wei Ning; Howard Gamper; Ya-Ming Hou; Ruben L. Gonzalez; Christine M. Dunham

Distant ribose 2′-O-methylation of 23S rRNA helix 69 pre-orders the capreomycin drug binding pocket at the ribosome subunit interface 23S rRNA远端核糖2′-O-甲基化预构象了放线菌素药物结合口袋，位于核糖体亚基界面处。

NUCLEIC ACIDS RESEARCH

IF13.1

2025-07-22

OAAI

Nandi, Suparno; Dey, Debayan; Srinivas, Pooja; Dunham, Christine M.; Conn, Graeme L.

Antitoxin control of optimal transcriptional repression in the atypical HigB-HigA toxin-antitoxin system from Proteus vulgaris 普罗威斯登菌中非典型HigB-HigA毒素-抗毒素系统的抗毒素对最佳转录抑制的控制

NUCLEIC ACIDS RESEARCH

IF13.1

2025-07-22

OAAI

Pavelich, Ian J.; Schureck, Marc A.; Srinivas, Pooja; Blackburn, Taylor M.; Wang, Dongxue; Hoffer, Eric D.; Boamah, Michelle; Zaldana, Kimberly; Onuoha, Nina; Miles, Stacey J.; Grabowicz, Marcin; Okafor, C. Denise; Dunham, Christine M.

The Escherichia coli RelB antitoxin C terminus is essential for RelE toxin suppression and transcriptional repression 大肠杆菌(Escherichia coli) RelB抗毒素的C末端对于RelE毒素的抑制和转录抑制至关重要。

Journal of Biological Chemistry

IF3.9

2025-06-18

OAAI

Julia Tanquary; Ian J. Pavelich; Marcin Grabowicz; Christine M. Dunham

Regulation, structure, and activity of the Pseudomonas aeruginosa MexXY efflux system

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2025-04-01

OAAI

Kavanaugh, Logan G.; Hinrichsen, Megan E.; Dunham, Christine M.; Conn, Graeme L.

N1-Methylpseudouridine and pseudouridine modifications modulate mRNA decoding during translation

NATURE COMMUNICATIONS

IF15.7

2024-09-16

OAAI

Monroe, Jeremy; Eyler, Daniel E.; Mitchell, Lili; Deb, Indrajit; Bojanowski, Abigail; Srinivas, Pooja; Dunham, Christine M.; Roy, Bijoyita; Frank, Aaron T.; Koutmou, Kristin S.

Antibiotic that inhibits trans-translation blocks binding of EF-Tu to tmRNA but not to tRNA

MBIO

IF4.7

2023-10-31

OAAI

Marathe, Neeraja; Nguyen, Ha An; Alumasa, John N.; Kuzmishin Nagy, Alexandra B.; Vazquez, Michael; Dunham, Christine M.; Keiler, Kenneth C.

30S subunit recognition and G1405 modification by the aminoglycoside- resistance 16S ribosomal RNA methyltransferase RmtC

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-06-12

OAAI

Srinivas, Pooja; Nosrati, Meisam; Zelinskaya, Natalia; Dey, Debayan; Comstock, Lindsay R.; Dunham, Christine M.; Conn, Graeme L.

Ratchet, swivel, tilt and roll: a complete description of subunit rotation in the ribosome

NUCLEIC ACIDS RESEARCH

IF13.1

2022-12-30

OAAI

Hassan, Asem; Byju, Sandra; Freitas, Frederico Campos; Roc, Claude; Pender, Nisaa; Nguyen, Kien; Kimbrough, Evelyn M.; Mattingly, Jacob M.; Gonzalez, Ruben L.; de Oliveira, Ronaldo Junio; Dunham, Christine M.; Whitford, Paul C.

Druggable differences: Targeting mechanistic differences between trans-translation and translation for selective antibiotic action

BIOESSAYS

IF2.7

2022-06-19

OAAI

Srinivas, Pooja; Keiler, Kenneth C.; Dunham, Christine M.

50S subunit recognition and modification by the Mycobacterium tuberculosis ribosomal RNA methyltransferase TlyA

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-03-31

OAAI

Laughlin, Zane T.; Nandi, Suparno; Dey, Debayan; Zelinskaya, Natalia; Witek, Marta A.; Srinivas, Pooja; Nguyen, Ha An; Kuiper, Emily G.; Comstock, Lindsay R.; Dunham, Christine M.; Conn, Graeme L.

ESKAPE velocity: total synthesis platforms promise to increase the pace and diversity of antibiotic development

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2021-12-27

PREAI

Mattingly, Jacob M.; Dunham, Christine M.

Oxidation alters the architecture of the phenylalanyl-tRNA synthetase editing domain to confer hyperaccuracy

NUCLEIC ACIDS RESEARCH

IF13.1

2021-09-28

OAAI

Srinivas, Pooja; Steiner, Rebecca E.; Pavelich, Ian J.; Guerrero-Ferreira, Ricardo; Juneja, Puneet; Ibba, Michael; Dunham, Christine M.

trans-Translation inhibitors bind to a novel site on the ribosome and clear Neisseria gonorrhoeae in vivo

NATURE COMMUNICATIONS

IF15.7

2021-03-19

OAAI

Aron, Zachary D.; Mehrani, Atousa; Hoffer, Eric D.; Connolly, Kristie L.; Srinivas, Pooja; Torhan, Matthew C.; Alumasa, John N.; Cabrera, Mynthia; Hosangadi, Divya; Barbor, Jay S.; Cardinale, Steven C.; Kwasny, Steven M.; Morin, Lucas R.; Butler, Michelle M.; Opperman, Timothy J.; Bowlin, Terry L.; Jerse, Ann; Stagg, Scott M.; Dunham, Christine M.; Keiler, Kenneth C.

Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing

ELIFE

IF0

2020-10-05

OAAI

Hoffer, Eric D.; Hong, Samuel; Sunita, S.; Maehigashi, Tatsuya; Gonzalez, Ruben L., Jr.; Whitford, Paul C.; Dunham, Christine M.

Disruption of evolutionarily correlated tRNA elements impairs accurate decoding

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-06-29

OAAI

Nguyen, Ha An; Sunita, S.; Dunham, Christine M.

Aminoglycoside conformation and ring substituents dictate evasion from bacterial resistance mechanisms

FASEB JOURNAL

IF4.2

2020-04-18

OAAI

Dey, Debayan; Hoffer, Eric; Francis, Dillion; Dunham, Christine; Conn, Graeme

Editorial: Ribosome survey and summary collection 2020

NUCLEIC ACIDS RESEARCH

IF13.1

2020-02-09

OAAI

Dunham, Christine M.; Dynan, William S.; Mankin, Alexander

Functionally critical residues in the aminoglycoside resistance-associated methyltransferase RmtC play distinct roles in 30S substrate recognition

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-11-01

OAAI

Nosrati, Meisam; Dey, Debayan; Mehrani, Atousa; Strassler, Sarah E.; Zelinskaya, Natalia; Hoffer, Eric D.; Stagg, Scott M.; Dunham, Christine M.; Conn, Graeme L.

研究方向