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E

Edward V. Prochownik

upmc children's hospital of pittsburgh

59H指数
277论文数
1.1W被引数
收录论文 105
发表时间
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Reversible dissociation of mitochondrial Complex V balances anabolic and energy-generating needs in cancer线粒体复合物V的可逆解离平衡了癌症中的合成代谢和能量生成需求
erriScience
IF4.1
err2026-02-02
err0
errOAAI
errHuabo Wang; Jie Lu; Colin Henchy; Steven J. Mullett; Adam C. Richert; Eric S. Goetzman; Ahmet Toksoz; Leonardo Hale; Brandon B. Wang; Nelli Mnatsakanyan; Edward V. Prochownik
err分享
err收藏
Derivation of Genetically Defined Murine Hepatoblastoma Cell Lines with Angiogenic Potential构建具有促血管生成潜能的基因定义性小鼠肝胚细胞瘤细胞系
errCancers 2025, Vol. 17, Page 3002
IF0
err2025-09-23
err0
errOAAI
errKeyao Chen; Ahmet Toksoz; Colin Henchy; Jessica Knapp; Jie Lu; Sarangarajan Ranganathan; Huabo Wang; Edward V. Prochownik
err分享
err收藏
SLC6A8-mediated creatine uptake suppresses ERK2-FSP1 signaling and induces ferroptosis in colorectal cancerSLC6A8介导的肌酸摄取抑制ERK2-FSP1信号通路并诱导结直肠癌的铁死亡。
errCell Reports
IF6.9
err2025-09-01
err0
errOAAI
errXiaojun Zhou; Genxin Wang; Yuhang Wu; Mingzhi Wu; Xiang Zhai; Chenhui Tian; Edward V. Prochownik; Congqing Jiang; Youjun Li
err分享
err收藏
Efficient derivation of immortalized, isogenic cell lines from genetically defined murine hepatoblastomas从基因定义的鼠肝母细胞瘤中高效衍生永生化和同源细胞系
errBiochemical and Biophysical Research Communications
IF2.2
err2025-08-13
err0
errOAAI
errHuabo Wang; Jie Lu; Keyao Chen; Bingwei Ma; Colin Henchy; Jessica Knapp; Sarangarajan Ranganathan; Edward V. Prochownik
err分享
err收藏
MYC Binding Near Transcriptional End Sites Regulates Basal Gene Expression, Read-Through Transcription, and Intragenic ContactsMYC结合在转录终止位点附近调节基础基因表达、转录穿透和基因内接触
errAdvanced Science
IF14.1
err2025-05-30
err0
errOAAI
errHuabo Wang; Bingwei Ma; Taylor Stevens; Jessica Knapp; Jie Lu; Edward V. Prochownik
err分享
err收藏
Gast-Mediated Suppression of Hepatoblastoma TumorigenesisGast介导的肝母细胞瘤肿瘤发生抑制
errAMERICAN JOURNAL OF PATHOLOGY
IF3.6
err2025-01-01
err0
errOAAI
errChen, KY; Wang, HB; Ma, BW; Knapp, J; Henchy, C; Lu, J; Stevens, T; Ranganathan, S; Prochownik, EV
err分享
err收藏
ZDHHC3-mediated SCAP S-acylation promotes cholesterol biosynthesis and tumor immune escape in hepatocellular carcinoma
errCELL REPORTS
IF6.9
err2024-11-01
err0
errOAAI
errWu, Mingzhi; Zhou, Xiaojun; Zhou, Xinyi; Wang, Genxin; Zeng, Yiqun; Li, Jun; Prochownik, V. Edward; Wang, Fubing; Li, Youjun
err分享
err收藏
Increases in 4-Acetaminobutyric Acid Generated by Phosphomevalonate Kinase Suppress CD8+ T Cell Activation and Allow Tumor Immune Escape
errADVANCED SCIENCE
IF14.1
err2024-09-26
err0
errOAAI
errZhou, Xinyi; Chen, Zhiqiang; Yu, Yijiang; Li, Mengjiao; Cao, Yu; Prochownik, Edward V.; Li, Youjun
err分享
err收藏
Inhibition of DUSP18 impairs cholesterol biosynthesis and promotes anti-tumor immunity in colorectal cancer
errNATURE COMMUNICATIONS
IF15.7
err2024-07-12
err4
errOAAI
errZhou, Xiaojun; Wang, Genxin; Tian, Chenhui; Du, Lin; Prochownik, Edward V.; Li, Youjun
err分享
err收藏
Body-Wide Inactivation of the Myc-Like Mlx Transcription Factor Network Accelerates Aging and Increases the Lifetime Cancer Incidence
errADVANCED SCIENCE
IF14.1
err2024-07-08
err0
errOAAI
errWang, Huabo; Stevens, Taylor; Lu, Jie; Roberts, Alexander; Van't Land, Clinton; Muzumdar, Radhika; Gong, Zhenwei; Vockley, Jerry; Prochownik, Edward V.
err分享
err收藏
Premature aging and reduced cancer incidence associated with near-complete body-wide Myc inactivation
errCELL REPORTS
IF6.9
err2023-08-01
err11
errOAAI
errWang, Huabo; Lu, Jie; Stevens, Taylor; Roberts, Alexander; Mandel, Jordan; Avula, Raghunandan; Ma, Bingwei; Wu, Yijen; Wang, Jinglin; Van't Land, Clinton; Finkel, Toren; Vockley, Jerry E.; Airik, Merlin; Airik, Rannar; Muzumdar, Radhika; Gong, Zhenwei; Torbenson, Michel S.; Prochownik, Edward V.
err分享
err收藏
P53 deficiency affects cholesterol esterification to exacerbate hepatocarcinogenesisP53缺乏症影响胆固醇酯化加剧肝癌
errHEPATOLOGY
IF15.8
err2023-04-17
err37
errOAAI
errZhu, Yahui; Gu, Li; Lin, Xi; Zhou, Xinyi; Lu, Bingjun; Liu, Cheng; Li, Yajun; Prochownik, Edward V.; Karin, Michael; Wang, Fubing; Li, Youjun
err分享
err收藏
The negative c-Myc target onzin affects proliferation and apoptosis via its obligate interaction with phospholipid scramblase I
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err53
errOAAI
errLi, YJ; Rogulski, K; Zhou, QS; Sims, PJ; Prochownik, EV
err分享
err收藏
Phosphomevalonate Kinase Controls β-Catenin Signaling via the Metabolite 5-Diphosphomevalonate磷酸甲基戊酸激酶通过代谢产物5-二磷酸甲基戊酸控制 β-连环蛋白信号传导
errADVANCED SCIENCE
IF14.1
err2023-02-21
err4
errOAAI
errChen, Zhiqiang; Zhou, Xinyi; Zhou, Xiaojun; Tang, Yi; Lu, Mingzhu; Zhao, Jianhong; Tian, Chenhui; Wu, Mingzhi; Liu, Yanliang; Prochownik, Edward V.; Wang, Fubing; Li, Youjun
err分享
err收藏
p53 promotes peroxisomal fatty acid β-oxidation to repress purine biosynthesis and mediate tumor suppressionp53促进过氧化物酶体脂肪酸 β-氧化抑制嘌呤生物合成并介导肿瘤抑制
errCELL DEATH & DISEASE
IF9.6
err2023-02-07
err8
errOAAI
errZhao, Jianhong; Zhou, Xiaojun; Chen, Baoxiang; Lu, Mingzhu; Wang, Genxin; Elumalai, Nagarajan; Tian, Chenhui; Zhang, Jinmiao; Liu, Yanliang; Chen, Zhiqiang; Zhou, Xinyi; Wu, Mingzhi; Li, Mengjiao; Prochownik, Edward V.; Tavassoli, Ali; Jiang, Congqing; Li, Youjun
err分享
err收藏
Disruption of Multiple Overlapping Functions Following Stepwise Inactivation of the Extended Myc Network
errCELLS
IF5.2
err2022-12-16
err3
errOAAI
errWang, Huabo; Stevens, Taylor; Lu, Jie; Airik, Merlin; Airik, Rannar; Prochownik, Edward V.
err分享
err收藏
Regulation of Normal and Neoplastic Proliferation and Metabolism by the Extended Myc Network
errCELLS
IF5.2
err2022-12-08
err8
errOAAI
errProchownik, Edward V.
err分享
err收藏
Posttranslational control of lipogenesis in the tumor microenvironment肿瘤微环境中脂肪生成的翻译后控制
errJOURNAL OF HEMATOLOGY & ONCOLOGY
IF40.4
err2022-08-29
err18
errOAAI
errZhu, Yahui; Lin, Xingrong; Zhou, Xiaojun; Prochownik, Edward, V; Wang, Fubing; Li, Youjun
err分享
err收藏
Normal and Neoplastic Growth Suppression by the Extended Myc Network
errCELLS
IF5.2
err2022-02-21
err13
errOAAI
errProchownik, Edward V.; Wang, Huabo
err分享
err收藏
Ceramide-mediated gut dysbiosis enhances cholesterol esterification and promotes colorectal tumorigenesis in mice
errJCI INSIGHT
IF6.1
err2022-02-08
err27
errOAAI
errZhu, Yahui; Gu, Li; Lin, Xi; Zhang, Jinmiao; Tang, Yi; Zhou, Xinyi; Lu, Bingjun; Lin, Xingrong; Liu, Cheng; Prochownik, Edward, V; Li, Youjun
err分享
err收藏

研究方向

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合作学者
合作期刊
M
Michael Karin
H 指数: 254 · 论文数: 904
D
Donna Neuberg
H 指数: 155 · 论文数: 1.7K
S
Simon C. Watkins
H 指数: 147 · 论文数: 1.1K
A
Arnold Münnich
H 指数: 129 · 论文数: 960
F
Fadlo R. Khuri
H 指数: 122 · 论文数: 1.1K
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